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Keywords Hyaluronic and osteoarthritis ...

Hyaluronic and osteoarthritis or tendon

https://read.qxmd.com/read/37959358/rehabilitation-of-soccer-players-knee-injuries-cartilage-reconstruction-anterior-cruciate-ligament-surgery-and-intensive-recovery-a-pilot-study
#1
JOURNAL ARTICLE
Bartłomiej Kacprzak, Karolina Rosińska
Knee injuries, particularly anterior cruciate ligament (ACL) damage and cartilage defects, are highly prevalent among athletes and affect their sports performance and long-term joint function. The purpose of this research was to evaluate the effectiveness of a comprehensive combination therapy approach for individuals with ACL and cartilage injuries. Twelve professional soccer players aged 18 to 30 years underwent bone-tendon-bone ACL reconstruction, microfracture cartilage repair surgery, and hyaluronic acid scaffold treatment...
November 1, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37841358/bmp2-and-gdf5-for-compartmentalized-regeneration-of-the-scapholunate-ligament
#2
JOURNAL ARTICLE
Hayman Lui, Cedryck Vaquette, Janet M Denbeigh, Randy Bindra, Andre J van Wijnen, Sanjeev Kakar
Background  Chronic injuries to the scapholunate ligament (SLIL) alter carpal kinematics and may progress to early degenerative osteoarthritis. To date, there is no consensus for the best method for SLIL reconstruction. This study aims to assess the use of growth factors (bone morphogenetic protein [BMP]2 and growth and differentiation factor 5 [GDF5]) for compartmentalized regeneration of bone and ligament in this multiphasic scaffold in a rabbit knee model. Case Description  A total of 100 µg of BMP2 and 30 µg of GDF5 were encapsulated into a heparinized gelatin-hyaluronic acid hydrogel and loaded into the appropriate compartment of the multiphasic scaffold...
October 2023: Journal of Wrist Surgery
https://read.qxmd.com/read/37590853/joint-and-soft-tissue-injections
#3
JOURNAL ARTICLE
Julie A Creech-Organ, Sarah E Szybist, Jacqueline L Yurgil
Joint and soft tissue injections can be divided into two primary categories: diagnostic and therapeutic. Diagnostic injections facilitate a diagnosis by using a local anesthetic to identify the site of pain or through fluid aspiration for analysis. Therapeutic injections are categorized by the type of injectate and include corticosteroids, hyaluronic acid, dextrose prolotherapy, and platelet-rich plasma. Diagnostic and therapeutic injections are most accurate under direct visualization. Corticosteroid injections help treat adhesive capsulitis and tenosynovitis but are not recommended for intratendinous injections...
August 2023: American Family Physician
https://read.qxmd.com/read/36437323/comparative-efficacy-of-the-stromal-vascular-fraction-cells-of-lipoaspirate-and-hyaluronic-acid-in-the-treatment-of-gonarthrosis-results-of-an-interim-analysis
#4
JOURNAL ARTICLE
E Ya Shevela, T R Glebova, M A Kotova, N A Nitsa, Yu A Kozhevnikov, I V Meledina, A A Ostanin, E R Chernykh
The use of cell technologies, in particular the stromal-vascular fraction of adipose tissue, is a new direction in the treatment of osteoarthritis of the weight-bearing joints. Stromal-vascular fraction cells have anti-inflammatory and immunomodulatory effects and are able to differentiate into connective tissue cells, including cartilage, tendons, and ligaments. Our clinical study showed the safety and good tolerability of intra-articular administration of autologous stromal-vascular fraction cells in 16 patients with severe manifestations of osteoarthritis...
November 28, 2022: Bulletin of Experimental Biology and Medicine
https://read.qxmd.com/read/36077161/cross-linked-hyaluronate-and-corticosteroid-combination-ameliorate-the-rat-experimental-tendinopathy-through-anti-senescent-and-apoptotic-effects
#5
JOURNAL ARTICLE
Po-Yen Ko, Che-Chia Hsu, Shih-Yao Chen, Li-Chieh Kuo, Wei-Ren Su, I-Ming Jou, Fong-Chin Su, Po-Ting Wu
The combination of cross-linked hyaluronate (cHA) and corticosteroid showed more rapid pain or functional improvement in knee osteoarthritis and adhesive capsulitis. However, rare evidence of this combination in treating tendinopathy has been reported. We hypothesized that the specific formulations of cHA and dexamethasone (DEX) conferred amelioration of tendinopathy via anti-apoptosis and anti-senescence. In this controlled laboratory study, primary tenocytes from the human tendinopathic long head of biceps were treated with three cHA formulations (cHA:linealized HA = 80:20, 50:50, and 20:80) + DEX with or without IL-1β stimulation...
August 28, 2022: International Journal of Molecular Sciences
https://read.qxmd.com/read/34353568/nonoperative-and-operative-soft-tissue-and-cartilage-regeneration-and-orthopaedic-biologics-of-the-knee-an-orthoregeneration-network-on-foundation-review
#6
JOURNAL ARTICLE
Derrick M Knapik, Aghogho Evuarherhe, Rachel M Frank, Matthias Steinwachs, Scott Rodeo, Marcus Mumme, Brian J Cole
Orthoregeneration is defined as a solution for orthopedic conditions that harnesses the benefits of biology to improve healing, reduce pain, improve function, and optimally, provide an environment for tissue regeneration. Options include: drugs, surgical intervention, scaffolds, biologics as a product of cells, and physical and electro-magnetic stimuli. The goal of regenerative medicine is to enhance the healing of tissue after musculoskeletal injuries as both isolated treatment and adjunct to surgical management, using novel therapies to improve recovery and outcomes...
August 2021: Arthroscopy
https://read.qxmd.com/read/33424096/mesenchymal-stem-cells-for-treatment-of-tendon-and-ligament-injuries-clinical-evidence
#7
JOURNAL ARTICLE
Suad Trebinjac, Mourad Gharairi
INTRODUCTION: Sport injuries, most of the time affect muscles, tendons, ligaments, cartilage and bones and range from very mild to severe, prompting different therapeutic approaches. Overuse is the most common cause of sports injuries and half of those injuries affect tendon, tendon sheet and tendon insertion to the bone. The number of ligament injuries, particularly anterior cruciate ligament (ACL) increasing. AIM: We were searching PubMed, Google Scholar and Medline focusing on human clinical studies related to stem cell therapy for tendinopathies and ligament injuries...
October 2020: Medical Archives
https://read.qxmd.com/read/32107725/injection-techniques-for-common-chronic-pain-conditions-of-the-foot-a-comprehensive-review
#8
REVIEW
Ivan Urits, Daniel Smoots, Henry Franscioni, Anjana Patel, Nathan Fackler, Seth Wiley, Amnon A Berger, Hisham Kassem, Richard D Urman, Laxmaiah Manchikanti, Alaa Abd-Elsayed, Alan D Kaye, Omar Viswanath
PURPOSE OF REVIEW: This is a comprehensive literature review of the available evidence and techniques of foot injections for chronic pain conditions. It briefly describes common foot chronic pain syndromes and then reviews available injection techniques for each of these syndromes, weighing the available evidence and comparing the available approaches. RECENT FINDINGS: Foot and ankle pain affects 20% of the population over 50 and significantly impairs mobility and ability to participate in activities of daily living (ADLs), as well as increases fall risk...
June 2020: Pain and Therapy
https://read.qxmd.com/read/30758709/the-use-of-prp-injections-in-the-management-of-knee-osteoarthritis
#9
REVIEW
Brendan O'Connell, Nicholas Martin Wragg, Samantha Louise Wilson
Osteoarthritis (OA) is a degenerative disease involving joint damage, an inadequate healing response and progressive deterioration of the joint architecture that commonly affects the knee and/or hip joints. It is a major world public health problem and is predicted to increase rapidly with an ageing population and escalating rate of obesity. Autologous blood-derived products possess much promise in the repair and regeneration of tissue and have important roles in inflammation, angiogenesis, cell migration and metabolism in pathological conditions, including OA...
May 2019: Cell and Tissue Research
https://read.qxmd.com/read/27790043/new-developments-in-the-treatment-of-osteoarthritis-focus-on-biologic-agents
#10
REVIEW
Jose Ignacio Torrero, Carlos Martínez
Osteoarthritis (OA) is one of the most common diseases around the world. Medical, social, and financial consequences oblige clinicians, surgeons, and researchers to focus on finding the best treatment option, to eradicate and stop this degenerative joint disease, in order to avoid surgical options which in many instances are over-indicated. Noninvasive treatments, such as anti-inflammatory drugs, physiotherapy, orthotic devices, dietary supplements, have demonstrated lack of effectiveness. The possibility to perform intra-articular injections with hyaluronic acid, corticosteroids, or the newest but criticized treatment based on platelet-rich plasma (PRP) has changed the management of OA disease...
2015: Open Access Rheumatology: Research and Reviews
https://read.qxmd.com/read/27695880/-current-aspects-of-therapy-of-rhizoarthrosis
#11
REVIEW
T Lögters, S Gehrmann, J Windolf
In patients with carpometacarpal osteoarthritis of the thumb, treatment strategies should be based on functional impairment and pain. Although X‑ray imaging is an integral component of the diagnostics, it is of subordinate importance for the therapy algorithm. Conservative therapy is always the first step in the chain of treatment. The efficacy of non-operative treatment, including intermittent immobilization using splinting and the application of technical assist devices in the daily routine has been proven to achieve pain relief...
December 2016: Der Unfallchirurg
https://read.qxmd.com/read/26554281/nonsurgical-management-of-knee-pain-in-adults
#12
JOURNAL ARTICLE
Brandon Q Jones, Carlton J Covey, Marvin H Sineath
The role of the family physician in managing knee pain is expanding as recent literature supports nonsurgical management for many patients. Effective treatment depends on the etiology of knee pain. Oral analgesics-most commonly nonsteroidal anti-inflammatory drugs and acetaminophen-are used initially in combination with physical therapy to manage the most typical causes of chronic knee pain. The American Academy of Orthopaedic Surgeons recommends against glucosamine/chondroitin supplementation for osteoarthritis...
November 15, 2015: American Family Physician
https://read.qxmd.com/read/26444018/hyaluronic-acid-increases-tendon-derived-cell-viability-and-collagen-type-i-expression-in-vitro-comparative-study-of-four-different-hyaluronic-acid-preparations-by-molecular-weight
#13
COMPARATIVE STUDY
Leonardo Osti, Martina Berardocco, Viviana di Giacomo, Graziella Di Bernardo, Francesco Oliva, Anna C Berardi
BACKGROUND: Hyaluronic Acid (HA) has been already approved by Food and Drug Administration (FDA) for osteoarthritis (OA), while its use in the treatment of tendinopathy is still debated. The aim of this study was to evaluate in human rotator cuff tendon derived cells the effects of four different HA on cell viability, proliferation, apoptosis and the expression of collagen type I and collagen type III. METHODS: An in vitro model was developed on human tendon derived cells from rotator cuff tears to study the effects of four different HA preparations (Ps) (sodium hyaluronate MW: 500-730 KDa - Hyalgan®, 1000 kDa Artrosulfur HA®, 1600 KDa Hyalubrix® and 2200 KDa Synolis-VA®) at various concentrations...
October 6, 2015: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/26313499/ultrasound-guided-interventional-procedures-around-the-shoulder
#14
REVIEW
Carmelo Messina, Giuseppe Banfi, Davide Orlandi, Francesca Lacelli, Giovanni Serafini, Giovanni Mauri, Francesco Secchi, Enzo Silvestri, Luca Maria Sconfienza
Ultrasound is an established modality for shoulder evaluation, being accurate, low cost and radiation free. Different pathological conditions can be diagnosed using ultrasound and can be treated using ultrasound guidance, such as degenerative, traumatic or inflammatory diseases. Subacromial-subdeltoid bursitis is the most common finding on ultrasound evaluation for painful shoulder. Therapeutic injections of corticosteroids are helpful to reduce inflammation and pain. Calcific tendinopathy of rotator cuff affects up to 20% of painful shoulders...
2016: British Journal of Radiology
https://read.qxmd.com/read/25626796/thumb-carpometacarpal-arthritis
#15
REVIEW
Karim Bakri, Steven L Moran
Osteoarthritis of the thumb carpometacarpal joint has a reported radiographic prevalence of 7 percent in men and 15 percent in women. Many patients remain minimally symptomatic; however, a subset of patients develop debilitating pain, weakness, and instability that severely limit hand function. Treatment options have focused on removal of the diseased trapezium and stabilization of the metacarpal base. Newer options, including carpometacarpal arthroplasty, may have a role in some patients for improving function...
February 2015: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/25295767/the-use-of-platelet-rich-plasma-for-the-treatment-of-osteoarthritis
#16
REVIEW
Prakash Jayabalan, Sarah Hagerty, Megan Helen Cortazzo
Osteoarthritis (OA) is the most common cause of disability in the United States. With an aging population, its incidence is only likely to rise. Articular cartilage has a poor capacity to heal. The advent of regenerative medicine has heralded a new approach to early treatment of degenerative conditions such as osteoarthritis by focusing on regenerating damaged tissue rather than focusing on replacement. Platelet-rich plasma (PRP) is one such treatment that has received much recent attention and has been used particularly for tendon healing...
September 2014: Physician and Sportsmedicine
https://read.qxmd.com/read/25051787/-complex-outpatient-care-to-patients-with-osteoarthrosis-and-degenerative-dystrophic-diseases-of-juxtaarticular-soft-tissues
#17
JOURNAL ARTICLE
L A Saks
The aim of the article is an evaluation of effectiveness of the complex outpatient care to patients with osteoarthrosis and degenerative-dystrophic diseases ofjuxtaarticular soft tissues. Recent researches showed that the key factors of the pathogenesis of diseases were degenerative-dystrophic and inflammatory changes in the synovio-entheseal complex ofparaarticular muscles' tendon. 411 patients with osteoarthrosis of 531 synovial joints and degenerative-dystrophic diseases of periarticular soft tissues underwent sequential corticosteroid therapy combined with hyaluronic acid injections...
April 2014: Voenno-medit︠s︡inskiĭ Zhurnal
https://read.qxmd.com/read/24895610/the-use-of-hyaluronic-acid-after-tendon-surgery-and-in-tendinopathies
#18
REVIEW
Michele Abate, Cosima Schiavone, Vincenzo Salini
Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials. A search of English-language articles was performed using the key search terms "hyaluronic acid" or "viscosupplementation" combined with "tendon," "tendinopathy," "adhesions," or "gliding," independently. In quite all the experimental studies, performed after surgical procedures for tendon injuries or in the treatment of chronic tendinopathies, using different hyaluronic acid compounds, positive results (reduced formation of scars and granulation tissue after tendon repair, less adhesions and gliding resistance, and improved tissue healing) were observed...
2014: BioMed Research International
https://read.qxmd.com/read/24817495/the-short-term-effect-after-a-single-injection-of-high-molecular-weight-hyaluronic-acid-in-patients-with-enthesopathies-lateral-epicondylitis-patellar-tendinopathy-insertional-achilles-tendinopathy-and-plantar-fasciitis-a-preliminary-study
#19
MULTICENTER STUDY
Tsukasa Kumai, Takeshi Muneta, Akihiro Tsuchiya, Masaharu Shiraishi, Yoshitaka Ishizaki, Kazuya Sugimoto, Norihiro Samoto, Shinji Isomoto, Yasuhito Tanaka, Yoshinori Takakura
BACKGROUND: Hyaluronic acid (HA) with a high molecular weight of 2700 kDa is approved in Japan to treat osteoarthritis of the knee, periarthritis scapulohumeralis, and knee pain associated with rheumatoid arthritis. The purpose of this preliminary study was to investigate the short-term efficacy, safety, and injectable volume of HA in the treatment of enthesopathies. METHODS: A total of 61 patients (16 with lateral epicondylitis, 14 with patellar tendinopathy, 15 with insertional Achilles tendinopathy, and 16 with plantar fasciitis) were each administered a single injection of HA (up to 2...
July 2014: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://read.qxmd.com/read/23294647/the-effects-of-hylan-g-f-20-surface-modification-on-gliding-of-extrasynovial-canine-tendon-grafts-in-vitro
#20
COMPARATIVE STUDY
Michail N Kolodzinskyi, Chunfeng Zhao, Yu-Long Sun, Kai-Nan An, Andrew R Thoreson, Peter C Amadio, Steven L Moran
PURPOSE: Studies have shown that a lubricant exogenously applied on extrasynovial tendon surfaces can reduce the gliding resistance after flexor tendon repair; however, the reagents that have been tested are solely for experimental testing and are not available for clinical use. The purpose of this study was to investigate the effect of exogenously applied hylan G-F 20, a U.S. Food and Drug Administration-approved hyaluronic acid for the treatment of osteoarthritis, on extrasynovial tendon gliding resistance in an in vitro canine model...
February 2013: Journal of Hand Surgery
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