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"Electrocardiogram" OR "ECG" OR "EKG" OR "12 Lead"

Fábio Leitão, Eurico Moreira, Filipe Alves, Mário Lourenço, Olga Azevedo, João Gaspar, Luis A Rocha
Several devices and measurement approaches have recently been developed to perform ballistocardiogram (BCG) and seismocardiogram (SCG) measurements. The development of a wireless acquisition system (hardware and software), incorporating a novel high-resolution micro-electro-mechanical system (MEMS) accelerometer for SCG and BCG signals acquisition and data treatment is presented in this paper. A small accelerometer, with a sensitivity of up to 0.164 µs/µg and a noise density below 6.5 µg/ Hz is presented and used in a wireless acquisition system for BCG and SCG measurement applications...
October 13, 2018: Sensors
Nigel Gebodh, Zeinab Esmaeilpour, Devin Adair, Kenneth Chelette, Jacek Dmochowski, Adam J Woods, Emily S Kappenman, Lucas C Parra, Marom Bikson
Online imaging and neuromodulation is invalid if stimulation distorts measurements beyond the point of accurate measurement. In theory, combining transcranial Direct Current Stimulation (tDCS) with electroencephalography (EEG) is compelling, as both use non-invasive electrodes and image-guided dose can be informed by the reciprocity principle. To distinguish real changes in EEG from stimulation artifacts, prior studies applied conventional signal processing techniques (e.g. high-pass filtering, ICA). Here, we address the assumptions underlying the suitability of these approaches...
October 12, 2018: NeuroImage
Kahina Ghanem, A L Johnson
In laying hens, pre-recruitment ovarian follicles (1-8 mm diameter) are arranged as a continuum of size and predicted maturity. Cyclic recruitment of a pre-recruitment follicle to the preovulatory stage begins, in part, by the ability of the granulosa cell (GC) layer to initiate responsiveness to follicle stimulating hormone- (FSH-) induced cyclic adenosine monophosphate. The objective of this study was to determine if increased circulating concentrations of FSH during the ovulatory cycle increase the number of recruited follicles, in a dose-dependent manner...
October 12, 2018: General and Comparative Endocrinology
Elisabeth Kaiser, Qinghai Tian, Michael Wagner, Monika Barth, Wenying Xian, Laura Schroeder, Sandra Ruppenthal, Lars Kaestner, Ulrich Boehm, Philipp Wartenberg, Huiyan Lu, Sara M McMillin, Derek B Bone, Jürgen Wess, Peter Lipp
Aims: Signaling via Gq-coupled receptors is of profound importance in many cardiac diseases such as hypertrophy and arrhythmia. Nevertheless, owing to their widespread expression and the inability to selectively stimulate such receptors in vivo, their relevance for cardiac function is not well understood. We here use DREADD technology to understand the role of Gq-coupled signaling in vivo in cardiac function. Methods and Results: We generated a novel transgenic mouse line that expresses a Gq-coupled DREADD (Dq) in striated muscle under the control of the MCK promotor...
October 13, 2018: Cardiovascular Research
Gianluigi Rellini, Rita Piazza, Elvira Loiudice, Matteo Cassin, Guglielmo Bernardi, Daniela Pavan, Eugenio Cervesato, Gian L Nicolosi
AIM: The aim of this study is to report the heterogeneity of clinical presentation in Tako-Tsubo syndrome (TTS), including a significant prevalence of normal ECG and echocardiographic patterns in a series of consecutive patients from a single center. METHODS AND RESULTS: From our database we selected a total of 168 cases of TTS. A total of 140 of these (Group A); 14 men (10%), mean age 60.3 years, range 39-87; 126 women (90%), mean age 66.1 years, range 43-93; matched the following reported criteria: typical stenocardic pain immediately following an emotional acute stress, or acute medical or surgical event within the preceding 12 h; acute rise and fall of troponin release; absence of significant coronary disease at coronary angiography...
October 12, 2018: Journal of Cardiovascular Medicine
M Reinthaler, F Jung, K Empen
BACKGROUND: Remote ischemic preconditioning (RIPC) has been demonstrated to induce potent cardioprotection in individuals experiencing coronary ischemia. A protocol combining limb ischemia and electronic muscle stimulation of the ischemic skeletal muscle (RIPC+), performed in advance of coronary artery occlusion, was superior in terms of infarct size reduction when compared to RIPC alone. METHODS: This study was performed to evaluate the benefit of RIPC + in humans compared to a standard RIPC protocol and a control group...
October 9, 2018: Clinical Hemorheology and Microcirculation
Iwona Grabowska, Neha Sharma, Alina Vasilescu, Madalina Iancu, Gabriela Badea, Rabah Boukherroub, Satishchandra Ogale, Sabine Szunerits
Rapid and accurate diagnostic technologies for early-state identification of cardiovascular abnormalities have become of high importance to prevent and attenuate their progression. The capability of biosensors to determine an increase in the concentration of cardiovascular protein biomarkers in circulating blood immediately after a myocardial infarction makes them ideal point-of-care platforms and alternative approaches to electrocardiograms, chest X-rays, and different laboratory-based immunoassays. We report here a generic approach toward multianalyte sensing platforms for cardiac biomarkers by developing aptamer-based electrochemical sensors for brain natriuretic peptide (BNP-32) and cardiac troponin I (cTnI)...
September 30, 2018: ACS Omega
Hamed Beyramienanlou, Nasser Lotfivand
Database: The efficiency and robustness of the proposed method has been tested on Fantasia Database (FTD), MIT-BIH Arrhythmia Database (MIT-AD), and MIT-BIH Normal Sinus Rhythm Database (MIT-NSD). Aim: Because of the importance of QRS complex in the diagnosis of cardiovascular diseases, improvement in accuracy of its measurement has been set as a target. The present study provides an algorithm for automatic detection of QRS complex on the ECG signal, with the benefit of energy and reduced impact of noise on the ECG signal...
2018: Journal of Healthcare Engineering
Behnaz Esmaeili, Farhad Kaffashi, Wanchat Theeranaew, Aman Dabir, Samden D Lhatoo, Kenneth A Loparo
Objective: Seizure-related autonomic dysregulation occurs in epilepsy patients and may contribute to Sudden Unexpected Death in Epilepsy (SUDEP). We tested how different types of seizures affect baroreflex sensitivity (BRS) and heart rate variability (HRV). We hypothesized that BRS and HRV would be reduced after bilateral convulsive seizures (BCS). Methods: We recorded blood pressure (BP), electrocardiogram (ECG) and oxygen saturation continuously in patients ( n = 18) with intractable epilepsy undergoing video-EEG monitoring...
2018: Frontiers in Neurology
Christopher Melinosky, Shiming Yang, Peter Hu, HsiaoChi Li, Catriona H T Miller, Imad Khan, Colin Mackenzie, Wan-Tsu Chang, Gunjan Parikh, Deborah Stein, Neeraj Badjatia
Background: In the acute resuscitation period after traumatic brain injury (TBI), one of the goals is to identify those at risk for secondary neurological decline (ND), represented by a constellation of clinical signs that can be identified as objective events related to secondary brain injury and independently impact outcome. We investigated whether continuous vital sign variability and waveform analysis of the electrocardiogram (ECG) or photoplethysmogram (PPG) within the first hour of resuscitation may enhance the ability to predict ND in the initial 48 hours after traumatic brain injury (TBI)...
2018: Frontiers in Neurology
Kyuichi Niizeki, Tadashi Saitoh
Phase coupling of respiratory sinus arrhythmia (RSA) has been proposed to be an alternative measure for evaluating autonomic nervous system (ANS) activity. The aim of this study was to analyze how phase coupling of RSA is altered during sleep, in order to explore whether this measure is a predictor of slow wave sleep (SWS). Overnight electroencephalograms (EEG), electrocardiograms (ECG), and breathing using inductance plethysmography were recorded from 30 healthy volunteers (six females, age range 21-64, 31...
2018: Frontiers in Physiology
Paul Guedeney, Alaide Chieffo, Clayton Snyder, Julinda Mehilli, Anna Sonia Petronio, Bimmer E Claessen, Samantha Sartori, Thierry Lefèvre, Patrizia Presbitero, Piera Capranzano, Didier Tchétché, Alessandro Iadanza, Gennaro Sardella, Nicolas M Van Mieghem, Jaya Chandrasekhar, Birgit Vogel, Sabato Sorrentino, Deborah N Kalkman, Emanuele Meliga, Nicolas Dumonteil, Chiara Fraccaro, Daniela Trabattoni, Ghada Mikhail, Maria Cruz Ferrer, Christoph Naber, Peter Kievit, Usman Baber, Samin Sharma, Marie Claude Morice, Roxana Mehran
Pre-existing atrial fibrillation (AF) is common among patients who underwent transcatheter aortic valve implantation (TAVI) and has been associated with adverse outcomes. The specific impact of AF at baseline in women who underwent TAVI, however, remains unknown. The Women's International Transcatheter Aortic Valve Implantation is a prospective, multinational registry evaluating the safety and performance of contemporary TAVI in women in 19 centers between January 2013 and December 2015. Patients with available electrocardiogram at baseline were compared according to the presence of AF...
September 8, 2018: American Journal of Cardiology
Christopher J Hanrahan, Marc D Lindley, Michelle Mueller, Daniel Kim, Daniel Sommers, Glen Morrell, Andrew Redd, Kristi Carlston, Vivian S Lee
PURPOSE: To compare the diagnostic accuracy of established non-gadolinium (Gd)-enhanced magnetic resonance (MR) angiography protocols with Gd-enhanced MR angiography at 3T for evaluating lower extremity peripheral arterial disease (PAD). MATERIALS AND METHODS: From February 2014 to 2015, 20 patients with PAD and intermittent claudication (16 men; age range, 51-76 y; Fontaine stage II) underwent 3-station (abdominopelvic, thigh, and calf) non-Gd MR angiography and bolus-chase Gd MR angiography protocols performed at 3T (Siemens Tim Trio), including quiescent-interval single-shot (QISS) MR angiography for all 3 stations and a combination of quadruple inversion recovery (QIR) MR angiography for the abdominopelvic station and electrocardiogram-gated fast spin echo (ECG-FSE) MR angiography for the extremities...
October 11, 2018: Journal of Vascular and Interventional Radiology: JVIR
Leanne Jane Eveson, A Williams
We present the case of a 50-year-old, fit, asymptomatic gurkha officer. At a routine medical, an ECG showed T-wave inversion in the chest leads V3-6. Transthoracic echo showed left ventricular apical hypertrophy and cavity obliteration consistent with apical hypertrophic cardiomyopathy (ApHCM). Cardiac magnetic resonance imaging showed apical and inferior wall hypertrophy in the left ventricle with no aneurysm or scarring. A 24-hour monitor showed normal sinus rhythm with no evidence of non-sustained ventricular tachycardia...
October 12, 2018: Journal of the Royal Army Medical Corps
Min Ho Ju, Jin Hyung Huh, Chee-Hoon Lee, Ho Jin Kim, Hyung Gon Je, Joon Bum Kim, Sung-Ho Jung, Jae Won Lee
BACKGROUND: Data on robotic-assisted surgical atrial fibrillation (AF) ablation in patients undergoing mitral valve (MV) surgeries are lacking. This study aimed to evaluate early and late outcomes following robotic-assisted ablation of AF combined with MV surgery. METHODS: Between 2007 and 2017, this study enrolled 94 patients (53.9±12.7 years; 67 males) undergoing AF ablation using an argon-based flexible cryoablation system during robotic-assisted MV surgery...
October 11, 2018: Annals of Thoracic Surgery
Carolyne Ghobrial, Rodina Sobhy, Engy Mogahed, Hala Abdullatif, Hanaa El-Karaksy
BACKGROUND: Symptomatic bradycardia has been reported in adults treated for chronic hepatitis C using sofosbuvir based regimens. AIM: We studied the cardiac safety of sofosbuvir/ledipasvir in Egyptian children, treated for chronic hepatitis C. METHODS: The study included 40 hepatitis C virus infected children and adolescents 12-17 years old, using the combination of sofosbuvir (400 mg)/ledipasvir (90 mg) in a single oral tablet (Harvoni) taken daily for 12 weeks...
September 21, 2018: Digestive and Liver Disease
Mariana Mirabel, Thibaud Damy, Erwan Donal, Olivier Huttin, Fabien Labombarda, Jean-Christophe Eicher, Claudio Cervino, Marianna Laurito, Lucile Offredo, Muriel Tafflet, Xavier Jouven, Geltrude Giura, Michel Desnos, Xavier Jeunemaître, Jean-Philippe Empana, Philippe Charron, Gilbert Habib, Patricia Réant, Albert Hagège
BACKGROUND: Our knowledge of hypertrophic cardiomyopathy (HCM) mainly originates from quarternary centres. The objective is to assess the current management of HCM patients in a large multicentre French register according to the level of expertise. METHODS AND RESULTS: A total of 1431 HCM patients were recruited across 26 (11 expert and 15 non-expert) centres in REMY, a prospective hospital-based register of adult HCM patients. A sarcomeric origin was suspected in 1284 (89...
September 28, 2018: International Journal of Cardiology
Tobias Traupe, Michael Stoller, Steffen Gloekler, Pascal Meier, Christian Seiler
OBJECTIVE: To test the effect of long-term pegfilgrastim on collateral function and myocardial ischemia in patients with chronic stable coronary artery disease (CAD). METHODS: This was a prospective clinical trial with randomized 2:1 allocation to pegfilgrastim or placebo for 6 months. The primary study endpoint was collateral flow index (CFI) as obtained during a 1-minute ostial coronary artery balloon occlusion. CFI is the ratio of mean coronary occlusive divided by mean aortic pressure both subtracted by central venous pressure (mmHg/mmHg)...
October 13, 2018: European Journal of Clinical Investigation
Mark Froats, Andrew Reed, Richard Dionne, Justin Maloney, Susan Duncan, Rob Burns, Julie Sinclair, Michael Austin
BACKGROUND: Most patients transferred from a non-percutaneous coronary intervention (PCI) facility for primary PCI do not meet target reperfusion times. Direct transportation of patients with ST-elevation myocardial infarction (STEMI) from the scene by advanced life support (ALS) paramedics has been shown to improve reperfusion times and outcomes. OBJECTIVE: The aim of this study was to determine whether it is safe to bypass the closest hospital and transport by basic life support (BLS) provider to a PCI facility...
October 9, 2018: Journal of Emergency Medicine
Victoria Strong, Torsten Möller, Ann-Sofie Tillman, Stefan Träff, Louise Guevara, Mike Martin, Sharon Redrobe, Kate White
OBJECTIVE: To characterize the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam ± medetomidine) and their suitability for the immobilization of healthy chimpanzees undergoing cardiac assessment. STUDY DESIGN: Prospective, clinical, longitudinal study. ANIMALS: Six chimpanzees (Pan troglodytes) aged 4-16 years weighing 19.5-78.5 kg were anaesthetized on two occasions. METHODS: Anaesthesia was induced with tiletamine/zolazepam (TZ) (3-4 mg kg-1 ) or tiletamine/zolazepam (2 mg kg-1 ) and medetomidine (0...
August 23, 2018: Veterinary Anaesthesia and Analgesia
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