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"Electrocardiogram" OR "ECG" OR "EKG" OR "12 Lead"

Alpha Oumar Diallo, Asha Krishnaswamy, Stuart K Shapira, Matthew E Oster, Mary G George, Jenna C Adams, Elizabeth R Walker, Paul Weiss, Mohammed K Ali, Wendy Book
Background: The prevalence of moderate or complex (moderate-complex) congenital heart defects (CHDs) among adults is increasing due to improved survival, but many patients experience lapses in specialty care or their CHDs are undocumented in the medical system. There is, to date, no efficient approach to identify this population. Objective: To develop and assess the performance of a risk score to identify adults aged 20-60 years with undocumented specific moderate-complex CHDs from electronic health records (EHR)...
December 1, 2018: Journal of the American Medical Informatics Association: JAMIA
Philippe Ariès, Kahina Bensafia, Ali Mansour, Benoît Clément, Jean-Louis Vincent, Ba Vinh Nguyen
BACKGROUND: Wired electrocardiogram monitors are an important component of current perioperative monitoring. Wireless monitoring units could help reduce the number of cables attached to patients and thus improve anesthesia ergonomics and patient management. However, there is concern that electromagnetic interference generated by electrosurgical units may prevent effective wireless signals in the operating room. To evaluate the extent of this problem, we developed a Bluetooth electrocardiogram prototype monitor and compared its electrocardiogram traces to those captured with a standard wired electrocardiogram monitor in our operating room...
December 11, 2018: Anesthesia and Analgesia
Davide Ippolito, Luca Riva, Cammillo R Talei Franzesi, Cecilia Cangiotti, Andrea De Vito, Filiberto Di Gennaro, Gabriele D'andrea, Andrea Crespi, Sandro Sironi
PURPOSE: To evaluate the image quality and radiation dose exposure of low-dose coronary CTA (cCTA) study, reconstructed with the new model-based iterative reconstruction algorithm (IMR), compared with standard hybrid-iterative reconstruction (iDose4 ) cCTA in patients with suspected coronary artery disease. MATERIALS AND METHODS: Ninety-eight patients with an indication for coronary CT study were prospectively enrolled. Fifty-two patients (study group) underwent 256-MDCT low-dose cCTA (80 kV; automated-mAs; 60 mL of CM, 350 mgL/mL) with prospective ECG-triggering acquisition and IMR...
December 11, 2018: La Radiologia Medica
David M Thomas, Patrick D McLaughlin, James P Nugent, Sarah A Barrett, John R Mayo, Ana-Maria Bilawich, Graham C Wong, Savvas Nicolaou
PURPOSE: This retrospective study reports the frequency and severity of coronary artery motion on dual-source high-pitch (DSHP), conventional pitch single-source (SS), and dual-source dual-energy (DE) CT pulmonary angiography (CTPA) studies. METHODS: Two hundred eighty-eight consecutive patients underwent CTPA scans for suspected pulmonary embolism between September 1, 2013 and January 31, 2014. One hundred ninety-four at DSHP scans, 57 SS scans, and 37 DE scans were analyzed...
December 12, 2018: Emergency Radiology
Eunice Yuen, Maria Posada, Claire Smith, Katharine Thorn, Dale Greenwood, Michelle Burgess, Karim A Benhadji, Demetrio Ortega, Louise Chinchen, Jeffrey Suico
PURPOSE: Crenigacestat (LY3039478) is a Notch inhibitor currently being investigated in advanced cancer patients. Conducting clinical pharmacology studies in healthy subjects avoids nonbeneficial drug exposures in cancer patients and mitigates confounding effects of disease state and concomitant medications. METHODS: Three studies were conducted in healthy subjects, assessing safety, pharmacokinetics, effect on QT interval, and relative and absolute bioavailability of crenigacestat...
December 11, 2018: Cancer Chemotherapy and Pharmacology
Matthew M Schubert, Amy Clark, Annie B De La Rosa
Purpose: Traditional heart-rate monitoring through the use of electrocardiograms or chest-worn heart rate sensors can be challenging in certain sports or in field settings. New technologies, such as photoplethysmography (PPG), have enabled heart-rate monitoring at alternate sites. However, to date, the accuracy and validity of various PPG sensors has not been examined in detail. The purpose of the present investigation was to determine the validity of an arm-worn PPG sensor during yoga sequences...
June 2018: Sports Med Int Open
Deandra H Luong, Po-Yin Cheung, Megan O'Reilly, Tze-Fun Lee, Georg M Schmolzer
Background: In 2015, the neonatal resuscitation guidelines incorporated the use of electrocardiography (ECG) to monitor heart rate of newborns. However, previous studies have indicated that cardiac arrest with pulseless electrical activity rhythm (PEA) may occur in the delivery room, rendering this method problematic. Objective: To evaluate the accuracy of ECG and auscultation to assess heart rate during PEA. Methods: A total of 45 piglets (age 1-3 days, weight 1.7-2.3 kg) were exposed to 30 min normocapnic alveolar hypoxia followed by asphyxia until asystole, achieved by disconnecting the ventilator and clamping the endotracheal tube...
2018: Frontiers in Pediatrics
Beata Morawiec, Brygida Przywara-Chowaniec, Piotr Muzyk, Mariusz Opara, Lam Ho, Lui Chun Tat, Olivier Muller, Ewa Nowalany-Kozielska, Damian Kawecki
Background: Clinical short-term risk stratification is a recommended approach in patients with chest pain and possible acute myocardial infarction (AMI) to further improve high safety of biomarker-based rule-out algorithms. The study aim was to assess clinical performance of baseline concentrations of high-sensitivity cardiac troponin T (hs-TnT) and copeptin and the modified HEART score (mHS) in early presenters to the emergency department with chest pain. Methods: This cohort study included patients with chest pain with onset maximum of 6 h before admission and no persistent ST-segment elevation on electrocardiogram...
2018: Disease Markers
Syed Muhammad Anwar, Maheen Gul, Muhammad Majid, Majdi Alnowami
Automatic detection and classification of life-threatening arrhythmia plays an important part in dealing with various cardiac conditions. In this paper, a novel method for classification of various types of arrhythmia using morphological and dynamic features is presented. Discrete wavelet transform (DWT) is applied on each heart beat to obtain the morphological features. It provides better time and frequency resolution of the electrocardiogram (ECG) signal, which helps in decoding important information of a quasiperiodic ECG using variable window sizes...
2018: Computational and Mathematical Methods in Medicine
Elise Jortberg, Ikaro Silva, Viprali Bhatkar, Ryan S McGinnis, Ellora Sen-Gupta, Briana Morey, John A Wright, Jesus Pindado, Matt T Bianchi
Background: Although in-lab polysomnography (PSG) remains the gold standard for objective sleep monitoring, the use of at-home sensor systems has gained popularity in recent years. Two categories of monitoring, autonomic and limb movement physiology, are increasingly recognized as critical for sleep disorder phenotyping, yet at-home options remain limited outside of research protocols. The purpose of this study was to validate the BiostampRC® sensor system for respiration, electrocardiography (ECG), and leg electromyography (EMG) against gold standard PSG recordings...
2018: Nature and Science of Sleep
Catherine M Bulka, Martha L Daviglus, Victoria W Persky, Ramon A Durazo-Arvizu, James P Lash, Tali Elfassy, David J Lee, Alberto R Ramos, Wassim Tarraf, Maria Argos
OBJECTIVE: Cardiovascular disease (CVD) is a leading cause of mortality and morbidity in the USA. The role of occupational exposures to chemicals in the development of CVD has rarely been studied even though many agents possess cardiotoxic properties. We therefore evaluated associations of self-reported exposures to organic solvents, metals and pesticides in relation to CVD prevalence among diverse Hispanic/Latino workers. METHODS: Cross-sectional data from 7404 employed individuals, aged 18-74 years, enrolled in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) were analysed...
December 11, 2018: Heart: Official Journal of the British Cardiac Society
Attila Frigy, Irma Varga, Zoltán Fogarasi, Boglárka Belényi, Ildikó Kocsis
OBJECTIVE: To investigate the influence of sleep apnea on ECG and blood pressure monitoring parameters in patients with acute heart failure (AHF). METHODS: 51 hospitalized patients with AHF (13 women, 38 men, mean age 60.8 years) underwent 24-hour combined monitoring of ECG and blood pressure and sleep apnea testing before discharge. Heart rhythm (mean heart rate, arrhythmias, pauses, QT-interval, heart rate variability) and blood pressure (mean systolic and diastolic values, variability, Circadian variation) parameters were obtained for the whole day and for nighttime (22:00-06:00)...
December 11, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Ida T Fonkoue, Seth D Norrholm, Paul J Marvar, Yunxiao Li, Melanie L Kankam, Barbara O Rothbaum, Jeanie Park
Posttraumatic stress disorder (PTSD) is characterized by increased sympathetic nervous system (SNS) activity, blunted parasympathetic nervous system (PNS) activity, and impaired baroreflex sensitivity (BRS), which contribute to accelerated cardiovascular disease. Patients with PTSD also have chronic stress-related elevations in resting blood pressure (BP), often in the prehypertensive range; yet, it is unclear if elevated resting blood pressure (ERBP) augments these autonomic derangements in PTSD. We hypothesized that compared with normotensive PTSD (N-PTSD), those with ERBP (E-PTSD) have further increased SNS, decreased PNS activity, and impaired BRS at rest and exaggerated SNS reactivity, PNS withdrawal, and pressor responses during stress...
December 1, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Dafni Charisopoulou, George Koulaouzidis, Annika Rydberg, Henein Y Michael
BACKGROUND: Electromechanical (EM) coupling heterogeneity is significant in long QT syndrome (LQTS), particularly in symptomatic patients; EM window (EMW) has been proposed as an indicator of interaction and a better predictor of arrhythmia than QTc. AIM: To investigate the dynamic response of EMW to exercise in LQTS and its predictive value of arrhythmia. METHODS: Forty-seven LQTS carriers (45±15 years, 20 with arrhythmic events) and 35 controls underwent exercise echocardiogram...
December 9, 2018: Clinical Cardiology
Lena Klüser, Elizabeth T Maier, Gerhard Wess
BACKGROUND: Echocardiography and 24-hour ECG are the gold standard tests to diagnose dilated cardiomyopathy (DCM) in Doberman Pinschers (DP), but myocardial damage might be detected earlier using a high-sensitivity cardiac troponin I (hs-cTnI) assay. OBJECTIVE: To evaluate and compare an hs-cTnI assay (Advia Centaur TnI-Ultra assay) with a conventional cTnI assay in DP with different stages of DCM and in healthy DP. ANIMALS: Three hundred forty-five examinations from 162 DP with and 179 DP without DCM...
December 11, 2018: Journal of Veterinary Internal Medicine
Jennifer E Hibma, Hagop M Kantarjian, Daniel J DeAngelo, Joseph P Boni
AIM: To characterize the effect of inotuzumab ozogamicin on QT interval in patients with B-cell malignancies. METHODS: Data were pooled from three clinical studies including 250 patients (N=2743) who received inotuzumab ozogamicin monotherapy. Patients with relapsed/refractory acute lymphoblastic leukaemia (NCT01564784 and NCT01363297) received 1.8 mg m-2 per cycle in divided doses (mean Cmax 371 ng ml-1 ; considered therapeutic) and patients with relapsed/refractory non-Hodgkin lymphoma (NCT00868608) received 1...
December 8, 2018: British Journal of Clinical Pharmacology
Winnie Y Sohn, Anthony A Portale, Isidro B Salusky, Hao Zhang, Lucy L Yan, Bella Ertik, Shahnaz Shahinfar, Edward Lee, Bastian Dehmel, Bradley A Warady
The original version of this article unfortunately contained three mistakes. In Table 1, the last line under "Key Inclusion Criteria" should read "Normal or clinically acceptable ECGs at screening and at day - 1." In addition, the abbreviation "IP" in the legend to Table 1 stands for "investigational product."
December 7, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Stojan Peric, Bogdan Bjelica, Ksenija Aleksic, Masa Kovacevic, Edita Cvitan, Gorana Mandic Stojmenovic, Vidosava Rakocevic Stojanovic
Myotonic dystrophy type 2 (DM2) is a slowly progressive, autosomal-dominant disease. This is a multisystemic disorder that affects the heart, which is one of the main causes of morbidity and mortality in DM2. The aim of the study was to define cardiac impairments in patients with DM2 and its association with sociodemographic and clinical features of patients. This retrospective study comprised 62 adult patients with DM2 hospitalized at the Neurology Clinic, Clinical Center of Serbia from 2013 until 2018, who underwent electrocardiography (ECG) and echocardiography examinations...
December 7, 2018: Acta Neurologica Belgica
C G M J Eurlings, J J Boyne, R A de Boer, H P Brunner-La Rocca
Telemedicine in chronic diseases like heart failure is rapidly evolving and has two important goals: improving and individualising care as well as reducing costs. In this paper, we provide a critical and an updated review of the current evidence by discussing the most important trials, meta-analyses and systematic reviews. So far, evidence for the CardioMEMS device is most convincing. Other trials regarding invasive and non-invasive telemonitoring and telephone support show divergent results, but several meta-analyses and systematic reviews uniformly reported a beneficial effect...
December 10, 2018: Netherlands Heart Journal
F Daniel Ramirez, Mouhannad M Sadek, Isabelle Boileau, Mark Cleland, Pablo B Nery, Girish M Nair, Calum J Redpath, Martin S Green, Darryl R Davis, Karen Charron, Joshua Henne, Timothy Zakutney, Rob S B Beanlands, Benjamin Hibbert, George A Wells, David H Birnie
Aims: Electrical cardioversion is commonly performed to restore sinus rhythm in patients with atrial fibrillation (AF), but it is unsuccessful in 10-12% of attempts. We sought to evaluate the effectiveness and safety of a novel cardioversion protocol for this arrhythmia. Methods and results: Consecutive elective cardioversion attempts for AF between October 2012 and July 2017 at a tertiary cardiovascular centre before (Phase I) and after (Phase II) implementing the Ottawa AF cardioversion protocol (OAFCP) as an institutional initiative in July 2015 were evaluated...
December 7, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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