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https://www.readbyqxmd.com/read/30110060/cardioprotective-effect-of-preconditioning-is-more-efficient-than-postconditioning-in-rats-submitted-to-cardiac-ischemia-and-reperfusion1
#1
José Gustavo Padrão Tavares, Paolo Ruggero Errante, Tânia Carmem Peñaranda Govato, Ênio Rodrigues Vasques, Renato Ribeiro Nogueira Ferraz, Murched Omar Taha, Francisco Sandro Menezes-Rodrigues, Afonso Caricati-Neto
PURPOSE: To investigate the cardioprotective effects of ischemic preconditioning (preIC) and postconditioning (postIC) in animal model of cardiac ischemia/reperfusion. METHODS: Adult rats were submitted to protocol of cardiac ischemia/reperfusion (I/R) and randomized into three experimental groups: cardiac I/R (n=33), preCI + cardiac I/R (n=7) and postCI + cardiac I/R (n=8). After this I/R protocol, the incidence of ventricular arrhythmia (VA), atrioventricular block (AVB) and lethality (LET) was evaluated using the electrocardiogram (ECG) analysis...
July 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/30110049/carotid-sinus-massage-in-syncope-evaluation-a-nonspecific-and-dubious-diagnostic-method
#2
Tan Chen Wu, Denise T Hachul, Francisco Carlos da Costa Darrieux, Maurício I Scanavacca
BACKGROUND: Carotid sinus hypersensitivity (CSH) is a frequent finding in the evaluation of syncope. However, its significance in the clinical setting is still dubious. A new criterion was proposed by Solari et al. with a symptomatic systolic blood pressure (SBP) cut-off value of ≤ 85 mmHg to refine the vasodepressor (VD) response diagnosis. OBJECTIVE: To determine and compare the response to carotid sinus massage (CSM) in patients with and without syncope according to standard and proposed criteria...
July 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/30109991/pre-ejection-period-the-reason-why-the-electrocardiogram-q-wave-is-an-unreliable-indicator-of-pulse-wave-initialization
#3
Joel Cameron Balmer, Christopher G Pretty, Shaun Davidson, Thomas Desaive, Shun Kamoi, Antoine Pironet, Philippe Morimont, Nathalie Janssen, Bernard Lambermont, Geoffrey M Shaw, J Geoffrey Chase

 Pulse wave velocity measurements are an indicator of arterial stiffness and possible cardiovascular dysfunction. It is usually calculated by measuring the pulse transit time (PTT) over a known distance through the arteries. In animal studies, reliable PTT measures can be obtained using two pressure catheters. However, such direct, invasive methods are undesirable in clinical settings. A less invasive alternative measure of PTT is pulse arrival time (PAT), the time between the Q-wave of an electrocardiogram (ECG) and the arrival of the foot of the beats pressure waveform at one pressure catheter...
August 15, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/30109784/calcium-polystyrene-sulfonate-decreases-inter-dialytic-hyperkalemia-in-patients-undergoing-maintenance-hemodialysis-a-prospective-randomized-crossover-study
#4
Jing Wang, Meng-Meng Lv, Odeh Zach, Ling-Yu Wang, Meng-Ying Zhou, Gui-Rong Song, Xu Zhang, Hong-Li Lin
Hyperkalemia is a life-threatening emergency in maintenance hemodialysis (MHD) patients. This clinical trial investigated the efficacy and safety of calcium-polystyrene sulfonate (Ca-PS) in MHD patients with interdialytic hyperkalemia. A total of 58 hemodialysis patients with hyperkalemia (≥5.5 mol/L) were selected and administered either a 3-week Ca-PS (3 × 5 g/day) or a blank control following the model of a prospective, randomized, crossover clinical trial with a 1-week washout period. All patients were followed up for another 3 weeks for safety evaluations...
August 14, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/30109349/high-grade-atrioventricular-block
#5
Yinghao Lim, Devinder Singh, Kian Keong Poh
Atrioventricular (AV) block is an AV conduction disorder that can manifest in various settings, with varying symptomaticity and severity. The electrocardiogram is a key diagnostic tool for management, and careful interpretation is necessary to institute the correct management. We described two cases of patients with bradycardia due to AV blocks and discussed the electrocardiogram interpretation and management.
July 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/30109157/construction-of-an-electrocardiogram-database-including-12-lead-waveforms
#6
Dahee Chung, Junggu Choi, Jong-Hwan Jang, Tae Young Kim, JungHyun Byun, Hojun Park, Hong-Seok Lim, Rae Woong Park, Dukyong Yoon
Objectives: Electrocardiogram (ECG) data are important for the study of cardiovascular disease and adverse drug reactions. Although the development of analytical techniques such as machine learning has improved our ability to extract useful information from ECGs, there is a lack of easily available ECG data for research purposes. We previously published an article on a database of ECG parameters and related clinical data (ECG-ViEW), which we have now updated with additional 12-lead waveform information...
July 2018: Healthcare Informatics Research
https://www.readbyqxmd.com/read/30109153/electrocardiogram-sampling-frequency-range-acceptable-for-heart-rate-variability-analysis
#7
Ohhwan Kwon, Jinwoo Jeong, Hyung Bin Kim, In Ho Kwon, Song Yi Park, Ji Eun Kim, Yuri Choi
Objectives: Heart rate variability (HRV) has gained recognition as a noninvasive marker of autonomic activity. HRV is considered a promising tool in various clinical scenarios. The optimal electrocardiogram (ECG) sampling frequency required to ensure sufficient precision of R-R intervals for HRV analysis has not yet been determined. Here, we aimed to determine the acceptable ECG sampling frequency range by analyzing ECG signals from patients who visited an emergency department with the chief complaint of acute intoxication or overdose...
July 2018: Healthcare Informatics Research
https://www.readbyqxmd.com/read/30109032/-balanced-ischaemia-on-ecg-in-dual-territory-stemi
#8
Iswaree Devi Balakrishnan, Chee Yang Chin, Louis Teo, Boon Yew Tan, Khung Keong Yeo
Culprit lesion identification in ST elevation myocardial infarction (STEMI) is often guided by electrocardiogram (ECG) changes. However, in the setting of multi-vessel coronary artery occlusion, this can be challenging. We describe an interesting case of dual territory STEMI with unanticipated ECG changes that bring forth the concept of 'balanced ischaemia'. These seemingly bizarre findings are well explained using the fundamentals of electrocardiography reinstating its relevance in modern day cardiology.
August 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/30108652/the-relationship-between-compound-danshen-dripping-pills-with-isosorbide-mononitrate-in-the-treatment-of-elderly-patients-with-unstable-angina-pectoris
#9
Yulin Liang, Junbo Zou, Xiaofei Zhang, Yu Wang, Jia Tai, Dongyan Guo, Chunli Cui, Jing Wang, Jiangxue Cheng, Yajun Shi
Objective: To evaluate the clinical efficacy and safety of Compound Danshen Dripping Pill (CDDP) and Isosorbide Mononitrate (ISMN) in the treatment of unstable angina pectoris (UAP) in the elderly. Materials and Methods: CNKI, Wanfang, VIP, CBM, and PubMed databases were searched for appropriate articles without language limitations on keywords. RevMan 5.3 software was used to perform the meta-analysis. Results: This analysis compared CDDP with ISMN of 21 randomized controlled trials (RCTs) that involved a total of 2356 patients with UAP...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/30108611/low-dose-oral-haloperidol-does-not-prolong-qtc-interval-in-older-acutely-hospitalised-adults-a-subanalysis-of-a-randomised-double-blind-placebo-controlled-study
#10
Edmée Jm Schrijver, Maaike Verstraaten, Peter M van de Ven, Pierre M Bet, Astrid M van Strien, Carel de Cock, Prabath Wb Nanayakkara
Background: Haloperidol is the most frequently prescribed antipsychotic for delirium symptoms. The risk of QTc prolongation often raises concerns, although the effect of haloperidol on QTc interval has not yet been investigated in a randomised placebo-controlled fixed-dose study. Methods: A subanalysis of a randomised double-blind placebo-controlled study was conducted to evaluate the effect of prophylactic haloperidol 1 mg or placebo 1 mg orally twice-daily (maximum of 14 doses) on QTc interval in patients aged 70 years and over...
June 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/30107901/a-simplified-formula-discriminating-subtle-anterior-wall-myocardial-infarction-from-normal-variant-st-segment-elevation
#11
Emre Aslanger, Özlem Yıldırımtürk, Emrah Bozbeyoğlu, Barış Şimşek, Can Yücel Karabay, Ayça Türer Cabbar, Ömer Kozan, Muzaffer Değertekin
Benign variant (BV) ST-segment elevation (STE) is present in anterior chest leads in most individuals and may cause diagnostic confusion in patients presenting with chest pain. Recently, 2 regression formulas were proposed for differentiation of BV-STE from anterior ST-elevation myocardial infarction (MI) on the electrocardiogram, computation of which is heavily device-dependent. We hypothesized that a simpler visual-assessment-based formula, namely (R-wave amplitude in lead V4 + QRS amplitude in V2) - (QT interval in millimeters + STE60 in V3), will be noninferior to these formulas...
July 19, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30107540/thromboembolic-acute-myocardial-infarction-after-aortic-valve-replacement-using-the-freestyle-stentless-aortic-bioprosthesis-with-subcoronary-valve-replacement
#12
Yusuke Watanabe, Toru Naganuma, Yosuke Kitanaka, Sunao Nakamura
A 70-year-old woman with substernal chest pain lasting 2.5 h presented to the emergency department of our hospital. She had a history of aortic valve replacement with the Freestyle stentless aortic bioprosthesis for severe aortic regurgitation 7 years ago. The initial electrocardiogram showed sinus rhythm at a rate of 71 bpm with ST-segment slight elevation in leads II, III and aVF. She was diagnosed as having acute coronary syndrome and was referred for an urgent catheterization. Urgent coronary angiography revealed total occlusion in the distal segment of the right coronary artery...
August 10, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/30107511/diagnostic-performance-of-on-site-computed-ct-fractional-flow-reserve-based-on-fluid-structure-interactions-comparison-with-invasive-fractional-flow-reserve-and-instantaneous-wave-free-ratio
#13
Shinichiro Fujimoto, Tomonori Kawasaki, Kanako K Kumamaru, Yuko Kawaguchi, Tomotaka Dohi, Taichi Okonogi, Keiken Ri, Sou Yamada, Kazuhisa Takamura, Etsuro Kato, Yoshiteru Kato, Makoto Hiki, Shinya Okazaki, Shigeki Aoki, Dimitris Mitsouras, Frank J Rybicki, Hiroyuki Daida
Aims: We evaluated diagnostic accuracy of CT-fractional flow reserve (CT-FFR) computed on-site with a new vendor workstation, against invasive FFR as the reference standard. Methods and results: Retrospective analyses compared CT-FFR of 104 vessels with 30-90% diameter stenosis in 75 patients imaged using single-rotation 320 detector-row coronary CT angiography (CCTA) with invasive FFR performed within 90 days. Prospective ECG-gated CCTA included exposure of 70-99% of the R-R interval...
August 10, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/30107407/non-steroidal-anti-inflammatory-drugs-and-the-risk-of-out-of-hospital-cardiac-arrest-a-case-control-study
#14
Mohammad Bakhriansyah, Patrick C Souverein, Olaf H Klungel, Anthonius de Boer, Marieke T Blom, Hanno L Tan
Aims: Non-steroidal anti-inflammatory drugs (NSAIDs), particularly selective COX-2 inhibitors, are associated with an increased risk of cardiovascular adverse events. However, the association between these drugs and out-of-hospital cardiac arrest with electrocardiogram-documented ventricular tachycardia/ventricular fibrillation (VT/VF-OHCA) has not been studied yet. This study was aimed to evaluate the association between the use of selective COX-2 inhibitors or conventional NSAIDs and VT/VF-OHCA compared with non-use...
August 10, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/30107195/poincar%C3%A3-plot-indices-as-measures-of-sympathetic-cardiac-regulation-responses-to-psychological-stress-and-associations-with-pre-ejection-period
#15
Saif Rahman, Mathew Habel, Richard J Contrada
The Poincaré plot is a visual representation of the R-R time series within a Cartesian plane constructed by plotting each R-R interval as a function of the previous one. The plot can be characterized by parameters that quantify the standard deviation (SD) of short- and long-term R-R interval variability (SD1 and SD2, respectively). Claims regarding the use of Poincaré plot analysis as an alternative to conventional time-domain and spectral analytic measures of parasympathetic contributions to heart rate variability (HRV) have been evaluated somewhat extensively...
August 11, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/30106744/finger-to-heart-f2h-authentication-for-wireless-implantable-medical-devices
#16
Guanglou Zheng, Wencheng Yang, Craig Valli, Li Qiao, Rajan Shankaran, Mehmet A Orgun, Subhas Chandra Mukhopadhyay
Any proposal to provide security for Implantable Medical Devices (IMDs), such as cardiac pacemakers and defibrillators, has to achieve a trade-off between security and accessibility for doctors to gain access to an IMD, especially in an emergency scenario. In this paper, we propose a Finger-to-Heart (F2H) IMD authentication scheme to address this trade-off between security and accessibility. This scheme utilizes a patient's fingerprint to perform authentication for gaining access to the IMD. Doctors can gain access to the IMD and perform emergency treatment by scanning the patient's finger tip instead of asking the patient for passwords/security tokens thereby achieving the necessary trade-off...
August 10, 2018: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/30106699/multi-scaled-fusion-of-deep-convolutional-neural-networks-for-screening-atrial-fibrillation-from-single-lead-short-ecg-recordings
#17
Xiaomao Fan, Qihang Yao, Yunpeng Cai, Fen Miao, Fangmin Sun, Ye Li
Atrial fibrillation (AF) is one of the most common sustained chronic cardiac arrhythmia in elderly population, associated with a high mortality and morbidity in stroke, heart failure, coronary artery disease, systemic thromboembolism, etc. The early detection of AF is necessary for averting the possibility of disability or mortality. However, AF detection remains problematic due to its episodic pattern. In this paper, a multi-scaled fusion of deep convolutional neural network (MSCNN) is proposed to screen out AF recordings from single lead short ECG recordings...
August 7, 2018: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/30106201/acute-inferior-myocardial-infarction-with-right-ventricular-involvement-and-several-clinical-electrocardiographic-markers-of-poor-prognosis
#18
Javier García-Niebla, Andrés Ricardo Pérez-Riera, Raimundo Barbosa-Barros, Jorge Díaz-Muñoz, Rodrigo Daminello-Raimundo, Luiz Carlos de Abreu, Kjell Nikus
Right ventricular involvement in inferior myocardial infarction is a marker of poor prognosis. We present a case of a 62-year-old man with very recent onset of acute chest pain and cardiac shock with the triad of elevated jugular venous pressure, distension of the jugular veins on inspiration, and clear lung fields. In addition, the admission electrocardiogram showed a slurring J wave or lambda-like wave and conspicuous ST segment depression in several leads, predominantly in the lateral precordial (V4-V6), all clinical-electrocardiographic features of ominous prognosis...
August 14, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/30105655/treatment-and-monitoring-patterns-among-premenopausal-women-with-hr-her2-advanced-breast-cancer
#19
Anand A Dalal, Geneviève Gauthier, Patrick Gagnon-Sanschagrin, Rebecca Burne, Annie Guérin, Polly Niravath, Tania Small
INTRODUCTION: Premenopausal women with hormone receptor positive (HR+) and human epidermal growth factor receptor-2-negative (HER2-) advanced breast cancer (aBC) often present with aggressive tumor types that lead to poor prognosis, high rates of recurrence, and mortality. Although clinical guidelines provide evidence-based recommendations for optimal treatment and monitoring, there is a dearth of information regarding treatment and monitoring patterns in clinical practice. In this study, we describe treatment and monitoring patterns among premenopausal women with HR+/HER2- aBC in real-world practice...
August 13, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/30105608/-noninvasive-mapping-for-catheter-ablation-of-arrhythmias-using-the-cardioinsight%C3%A2-ecg-vest
#20
REVIEW
Kay Weipert, Malte Kuniss, Thomas Neumann
BACKGROUND: CardioInsight™ is a noninvasive three-dimensional mapping system technology which offers a unique method for arrhythmia characterization and localization. With a 252-lead ECG vest on the patient's torso and a noncontrast CT scan, epicardial potentials are detected and by means of reconstruction algorithms activation and phase maps are created, offering a deeper understanding of localization and mechanisms of arrhythmias including atrial fibrillation without the need for an endocardial catheter...
August 13, 2018: Herzschrittmachertherapie & Elektrophysiologie
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