keyword
https://read.qxmd.com/read/38536171/a-revised-definition-of-left-bundle-branch-block-using-time-to-notch-in-lead-i
#1
JOURNAL ARTICLE
Jeremy S Treger, Ahmad B Allaw, Pouyan Razminia, Dipayon Roy, Amulya Gampa, Swati Rao, Andrew D Beaser, Srinath Yeshwant, Zaid Aziz, Cevher Ozcan, Gaurav A Upadhyay
IMPORTANCE: Current left bundle branch block (LBBB) criteria are based on animal experiments or mathematical models of cardiac tissue conduction and may misclassify patients. Improved criteria would impact referral decisions and device type for cardiac resynchronization therapy. OBJECTIVE: To develop a simple new criterion for LBBB based on electrophysiological studies of human patients, and then to validate this criterion in an independent population. DESIGN, SETTING, AND PARTICIPANTS: In this diagnostic study, the derivation cohort was from a single-center, prospective study of patients undergoing electrophysiological study from March 2016 through November 2019...
March 27, 2024: JAMA Cardiology
https://read.qxmd.com/read/38529807/different-methods-of-3d-qrs-area-calculation-from-vectorcardiographic-x-y-and-z-leads
#2
JOURNAL ARTICLE
Amit Noheria, Christian Toquica, Uzair A Mahmood, Ashley DeBauge, Tucker Morey, Christopher J Harvey
3DQRSarea is a strong marker for cardiac resynchronization therapy and can be obtained by taking the (i) summation or the (ii) difference of the areas subtended by positive and negative deflections in X, Y, Z vectorcardiographic electrocardiogram (ECG) leads. We correlated both methods with the instantaneous-absolute-3D-voltage-time-integral (VTIQRS-3D ). 3DQRSarea consistently underestimated the VTIQRS -3D , but the summation method was a closer and more reliable approximation. The dissimilarity was less apparent in left bundle branch block (r2 summation ...
March 26, 2024: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/38527508/-diagnosis-and-treatment-of-arrhythmogenic-cardiomyopathy-in-children
#3
JOURNAL ARTICLE
W Q Ye, Y Y Xiao, X K Jiang, M Jin, X F Wang, W W Ding
Objective: To summarize the clinical manifestations, experiences in diagnosis and treatment of arrhythmogenic cardiomyopathy (ACM) in children. Methods: A retrospective analysis of the clinical manifestations, laboratory tests, radiological features, treatment and follow-up results was conducted in 11 children diagnosed with ACM at the center of congenital heart disease, Beijing anzhen hospital from May 2010 to March 2022. Results: A total of 11 patients aged 2 to 16 years, including 5 males and 6 females were diagnosed with ACM...
March 25, 2024: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/38524519/reversal-of-complete-atrioventricular-block-in-dialysis-patients-following-parathyroidectomy-a-case-report
#4
Shan-Shan Xu, Li-Hai Hao, Yan-Meng Guan
BACKGROUND: Refractory secondary hyperparathyroidism (SHPT) is a common complication observed in patients with end-stage renal disease and can result in ectopic calcification. Metastatic calcification involving the heart valves and the conduction system can easily lead to arrhythmias, including atrioventricular block. This case report describes a maintenance hemodialysis patient with refractory SHPT resulting in a complete atrioventricular block (CAVB), which was eventually reversed to a first-degree atrioventricular block...
March 6, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38524089/bradycardia-renal-failure-atrioventricular-block-shock-and-hyperkalemia-brash-syndrome-emergence-in-a-unique-intersection-of-covid-19-and-end-stage-renal-disease-a-case-report
#5
Tutul Chowdhury, Sindhu C Pokhriyal, Uma Gupta, Kalendra Kunwar, Kiran Hashmi, Sauraj Devkota, Morris Kopyt, Andleeb Sherazi
Bradycardia, renal failure, atrioventricular (AV) block, shock, and hyperkalemia (BRASH) syndrome is a rare clinical entity that poses challenges for healthcare practitioners. It is characterized by bradycardia, renal failure, atrioventricular (AV) obstruction, shock, and hyperkalemia. This case is an interesting instance of BRASH syndrome in the setting of COVID-19 infection and end-stage renal disease (ESRD). Initial laboratory results revealed macrocytic anemia, renal dysfunction, acidosis, and mild hyponatremia, along with hyperkalemia...
February 2024: Curēus
https://read.qxmd.com/read/38523980/myocardial-bridging-of-mid-left-anterior-descending-artery-lad-presenting-as-transient-left-bundle-branch-block-during-nuclear-stress-test
#6
Kai Shiang Lin, Adam Kurnick, Ridhima Goel, Igal Gorbut, Adam Friedman, Ezra Schrem, Samy I McFarlane, Inna Bukharovich
Transient left bundle branch block occurring during a nuclear stress test in the setting of myocardial bridging is a relatively rare finding. We report a case of a 75-year-old male who presented with typical stable angina. Serial troponins were negative, and the electrocardiogram revealed normal sinus rhythm with left ventricular hypertrophy and T-wave inversions in the lateral leads. The nuclear stress test was non-ischemic but showed a transient left bundle branch block associated with chest pain and shortness of breath that occurred right after the administration of regadenoson...
February 2024: Curēus
https://read.qxmd.com/read/38518637/exploring-the-role-and-mechanism-of-hyperoside-against-cardiomyocyte-injury-in-mice-with-myocardial-infarction-based-on-jak2-stat3-signaling-pathway
#7
JOURNAL ARTICLE
Tingcai Rao, Hua Tong, Jing Li, Jiahao Huang, Yanyan Yin, Junyan Zhang
BACKGROUND: Myocardial infarction (MI) is one of the most deadly diseases in the world. Hyperoside (Hyp) has been shown to have a protective effect on cardiovascular function through various signaling pathways, but whether it can protect myocardial infarction by regulating JAK2/STAT3 signaling pathway is unknown. AIM OF THE STUDY: To investigate whether Hyp could protect the heart against myocardial infarction injury in mice by modulating JAK2/STAT3 signaling pathway and its potential mechanism...
December 25, 2023: Phytomedicine
https://read.qxmd.com/read/38514200/twenty-four-hour-continuous-transvenous-temporary-right-ventricular-pacing-in-healthy-horses
#8
JOURNAL ARTICLE
Amanda Avison, Anna R Gelzer, Virginia B Reef, Kathryn B Wulster Bills, Cris Navas de Solis, Marc S Kraus, JoAnn Slack, Darko Stefanovski, Lindsay J Deacon, Claire Underwood
BACKGROUND: The ability to perform transvenous temporary cardiac pacing (TV-TP) is critical to stabilize horses with symptomatic bradyarrhythmias. Reports of successful TV-TP in horses are limited, and only briefly describe short-term pacing. OBJECTIVE: To describe temporary, medium-term (24 h) transvenous right ventricular pacing in awake horses using a bipolar torque-directed pacing catheter. ANIMALS: Six healthy adult institutional teaching horses...
March 21, 2024: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/38508296/predictors-of-pacemaker-requirement-in-patients-receiving-implantable-loop-recorders-for-unexplained-syncope-a-systematic-review-and-meta-analysis
#9
JOURNAL ARTICLE
Jeremy William, Shane Nanayakkara, David Chieng, Hariharan Sugumar, Liang-Han Ling, Hitesh Patel, Justin Mariani, Sandeep Prabhu, Peter M Kistler, Aleksandr Voskoboinik
BACKGROUND: Implantable loop recorders (ILR) are increasingly used to evaluate patients with unexplained syncope. Identification of all predictors of bradycardic syncope and consequent permanent pacemaker (PPM) insertion is of substantial clinical interest, as patients in the highest-risk category may benefit from upfront pacemaker insertion. OBJECTIVES: We performed a systematic review and meta-analysis to identify risk predictors for PPM insertion in ILR recipients with unexplained syncope...
March 18, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38506104/comparison-of-novel-telemonitoring-system-using-the-single-lead-electrocardiogram-patch-with-conventional-telemetry-system
#10
JOURNAL ARTICLE
Soonil Kwon, Eue-Keun Choi, So-Ryoung Lee, Seil Oh, Hee-Seok Song, Young-Shin Lee, Sang-Jin Han, Hong Euy Lim
BACKGROUND AND OBJECTIVES: Although a single-lead electrocardiogram (ECG) patch may provide advantages for detecting arrhythmias in outpatient settings owing to user convenience, its comparative effectiveness for real-time telemonitoring in inpatient settings remains unclear. We aimed to compare a novel telemonitoring system using a single-lead ECG patch with a conventional telemonitoring system in an inpatient setting. METHODS: This was a single-center, prospective cohort study...
March 2024: Korean Circulation Journal
https://read.qxmd.com/read/38504714/mechanisms-of-torsades-de-pointes-an-update
#11
REVIEW
Yukiomi Tsuji, Masatoshi Yamazaki, Masafumi Shimojo, Satoshi Yanagisawa, Yasuya Inden, Toyoaki Murohara
Torsades de Pointes (TdP) refers to a polymorphic ventricular tachycardia (VT) with undulating QRS axis that occurs in long QT syndrome (LQTS), although the term has been used to describe polymorphic ventricular tachyarrhythmias in which QT intervals are not prolonged, such as short-coupled variant of TdP currently known as short-coupled ventricular fibrillation (VF) and Brugada syndrome. Extensive works on LQTS-related TdP over more than 50 years since it was first recognized by Dessertennes who coined the French term meaning "twisting of the points", have led to current understanding of the electrophysiological mechanism that TdP is initiated by triggered activity due to early afterdepolarization (EAD) and maintained by reentry within a substrate of inhomogeneous repolarization...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38503487/presence-and-utility-of-electrocardiographic-abnormalities-in-long-term-childhood-cancer-survivors
#12
JOURNAL ARTICLE
Esmée C de Baat, Remy Merkx, Jan M Leerink, Coen Boerhout, Heleen J H van der Pal, Elvira C van Dalen, Jacqueline Loonen, Dorine Bresters, Eline van Dulmen-den Broeder, Margriet van der Heiden-van der Loo, Marry M van den Heuvel, Judith L Kok, Marloes Louwerens, Sebastian J C M M Neggers, Cecline M Ronckers, Jop C Teepen, Wim J E Tissing, Andrica C de Vries, Livia Kapusta, Leontien C M Kremer, Annelies M C Mavinkurve-Groothuis, Wouter E M Kok, Elizabeth A M Feijen
BACKGROUND: We assessed the prevalence and diagnostic value of ECG abnormalities for cardiomyopathy surveillance in childhood cancer survivors. METHODS: In this cross-sectional study, 1381 survivors (≥5 years) from the Dutch Childhood Cancer Survivor Study part 2 and 272 siblings underwent a long-term follow-up ECG and echocardiography. We compared ECG abnormality prevalences using the Minnesota Code between survivors and siblings, and within biplane left ventricular ejection fraction (LVEF) categories...
March 19, 2024: Heart
https://read.qxmd.com/read/38500683/estimating-left-ventricular-mass-from-the-electrocardiogram-across-the-spectrum-of-lv-mass-from-normal-to-increased-lv-mass-in-an-older-age-group
#13
JOURNAL ARTICLE
Simon W Rabkin, Jeremy C J Zhou
OBJECTIVES: To examine the relationship of QRS voltages and left ventricular (LV) mass across the spectrum of individuals with different LV mass. METHODS: Twenty QRS voltage measurements or combinations were determined in a consecutive series of 159 adults with an ECG and echocardiogram without previous myocardial infarction, left or right bundle branch block, pre-excitation, or electronic pacemaker. RESULTS: The four strongest and significant correlations between QRS and LV mass were S in V4, deepest S wave in any precordial lead plus S in V4, S in V3, and S in V3 plus R in AVL times QRS duration...
2024: Cardiology Research and Practice
https://read.qxmd.com/read/38496176/unmasking-coronary-artery-disease-with-intermittent-left-bundle-branch-block-a-case-report
#14
Kawthar A Alabdrabalrasol, Amal S Al Sulaiman, Lama T Alkhunaizi, Sajedh N Al Kazim, Dunya Alfaraj
Intermittent left bundle branch block (LBBB) is an unusual phenomenon, with very few cases documented in the literature. It is often considered a reflection of underlying conditions known to increase the risk of cardiovascular morbidity and death, including coronary artery disease (CAD), cardiomyopathy, hypertensive heart disease, and aortic valve disease. In rare instances, coronary vasospasm is the sole underlying condition. It is typically diagnosed by ECG and managed according to the underlying cause. We describe a case of intermittent LBBB presenting with chest pain...
February 2024: Curēus
https://read.qxmd.com/read/38495921/application-value-of-serum-cardiac-troponin-t-brain-natriuretic-peptide-levels-and-electrocardiogram-changes-in-the-treatment-and-prognosis-evaluation-of-severe-pneumonia-in-children
#15
JOURNAL ARTICLE
Liang Deng, Xiaojun Liu, Wei Liu
OBJECTIVE: To explore the application of serum cardiac troponin T (cTnT), brain natriuretic peptide (BNP) levels, and electrocardiogram changes in the treatment and prognosis evaluation of severe pneumonia in children. METHODS: 120 children with severe pneumonia (severe group) admitted to our hospital from June 2020 to December 2022 were selected as the study subjects with prospective study. They were divided into survival group (n=78) and death group (n=42) based on their survival status; 120 children with mild pneumonia were selected as the control group...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38495238/qualitative-and-quantitative-electrocardiogram-parameters-in-a-large-cohort-of-children-with-duchenne-muscle-dystrophy-in-comparison-with-age-matched-healthy-subjects-a-study-from-south-india
#16
JOURNAL ARTICLE
Manu S Girija, Deepak Menon, Kiran Polavarapu, Veeramani Preethish-Kumar, Seena Vengalil, Saraswati Nashi, Madassu Keertipriya, Mainak Bardhan, Priya T Thomas, Valasani R Kiran, Vikas Nishadham, Arun Sadasivan, Akshata Huddar, Gopi K Unnikrishnan, Ganagarajan Inbaraj, Arjun Krishnamurthy, Boris W Kramer, Talakad N Sathyaprabha, Atchayaram Nalini
BACKGROUND: Electrocardiography (ECG) remains an excellent screening tool for cardiac assessment in Duchenne muscular dystrophy (DMD), but an accurate interpretation requires comparison with age-matched healthy controls. OBJECTIVE: We examined various ECG parameters in children with DMD, in comparison with age-matched controls. METHODS: Standard 12-lead ECG tracings of serial patients were screened for quality and selected. Controls were healthy, age-matched school-going children...
2024: Annals of Indian Academy of Neurology
https://read.qxmd.com/read/38491719/discrimination-between-ventricular-tachycardia-and-wide-qrs-preexcited-tachycardia
#17
JOURNAL ARTICLE
Jae Hoon Lee
BACKGROUND: To develop a new algorithm to differentiate ventricular tachycardia (VT) from preexcited tachycardia (pre-ET) according to left bundle branch block (LBBB) and right bundle branch block (RBBB) patterns. METHODS: This study included 67 electrocardiograms (ECGs) with VT and 63 ECGs with pre-ET, collected from our hospital and through PubMed. Of those, 64 were allocated to the derivation cohort and the rest to the validation cohort. The diagnoses of the ECGs were confirmed using an electrophysiological study...
March 2024: Annals of Noninvasive Electrocardiology
https://read.qxmd.com/read/38490601/beyond-conduction-impairment-unveiling-the-profound-myocardial-injury-in-left-bundle-branch-block
#18
JOURNAL ARTICLE
Xiaoxian Wang, Beibei Ge, Changqing Miao, Christopher Lee, Jorge E Romero, Peng Li, Fang Wang, Di Xu, Minglong Chen, Dianfu Li, Dong Li, Mingxia Li, Fang Xu, Yan Li, Chanjuan Gong, Cynthia C Taub, Jing Yao
BACKGROUND: Left bundle branch block (LBBB) represents a frequently encountered conduction system disorder. Despite its widespread occurrence, a continual dilemma persists regarding its intricate association with underlying cardiomyopathy and its pivotal role in the initiation of dilated cardiomyopathy. The pathological alterations linked to LBBB-induced cardiomyopathy (LBBB-CM) have remained elusive. OBJECTIVE: This study sought to investigate the chronologic dynamics of LBBB to left ventricular dysfunction and pathological mechanism of LBBB-CM...
March 13, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38487120/hyperkalemia-induced-t-wave-oversensing-in-an-implantable-cardioverter-defibrillator
#19
Ariel Gonzalez, Hilton Franqui, Jose Lopez, Hector Banchs
A 66-year-old female with end-stage renal disease and heart failure with reduced ejection fraction, status post implantable cardioverter defibrillator (ICD) presented to the emergency department with dizziness and fatigue. An electrocardiogram showed sinus rhythm, complete atrioventricular block, and ventricular paced rhythm at 30 beats per minute (bpm). Device interrogation revealed a programmed VVI mode with a lower rate limit of 40 bpm and evidence of T wave oversensing. Serologic studies were remarkable for hyperkalemia (7...
February 2024: Curēus
https://read.qxmd.com/read/38487108/lyme-associated-pericarditis-a-case-report-and-literature-review
#20
Muhammad Atif Ameer, Sridhar Reddy Patlolla, Nimi Patel, Rahul Mehta, Maham Babar
Lyme disease is caused by  Borrelia burgdorferi (B. burgdorferi), which  is a spirochete transmitted by ticks of the genus  Ixodes . Complications related to the cardiovascular system usually occur in the early phase of infection, and the most common cardiovascular complication of Lyme disease is atrioventricular block, especially third-degree heart block. We report a case of a young Caucasian male patient who presented to the emergency department (ED) with complaints of chest pain and shortness of breath...
February 2024: Curēus
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