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"Nasogastric Tube" OR "Orogastric Tube"

E Daniel, M J Whitaker, B Keevil, J Wales, R J Ross
OBJECTIVE: Hydrocortisone via nasogastric (NG) tube is used in sick children with adrenal insufficiency; however, there is no licensed formulation for NG administration. METHODS: We investigated hydrocortisone recovery after passage through NG tubes in vitro for 3 formulations: liquid suspension, crushed tablets mixed with water, and hydrocortisone granules designed for oral administration to children. Cortisol was measured by LC-MS/MS. RESULTS: Hydrocortisone content was variable and recovery low after preparation in syringe and prior to passage through NG tubes...
October 12, 2018: Clinical Endocrinology
Gretchen Glaser, Sean C Dowdy, Abraham Peedicayil
Enhanced recovery protocols consist of a bundle of concepts including early feeding, opioid-sparing multimodal pain management, and euvolemia, with the overarching goal of hastening postoperative recovery. Enhanced recovery after surgery has been shown to reduce hospital length of stay, reduce costs, and decrease perioperative opioid requirements in benign and oncologic gynecologic surgery. Interventions without supporting evidence of benefit, such as the use of mechanical bowel preparation, routine use of nasogastric tubes and surgical drains, caloric restriction, routine use of intravenous opioid analgesics, and over-vigorous intravenous hydration should be discouraged to improve broader endpoints such as patient satisfaction and overall recovery...
October 2018: International Journal of Gynaecology and Obstetrics
Aurélien Venara, Pascal Alfonsi, Eddy Cotte, Jérôme Loriau, Jean-François Hamel, Karem Slim
PURPOSE: Postoperative ileus (POI) occurrence within enhanced recovery programs (ERPs) has decreased. Also, intra-abdominal complications (IAC) such as anastomotic leakage (AL) generally present late. The aim was to characterize the link between POI and the other complications occurring after surgery. METHODS: This retrospective analysis of a prospective database was conducted by the Francophone Group for Enhanced Recovery after Surgery. POI was considered to be present if gastrointestinal functions had not been recovered within 3 days following surgery or if a nasogastric tube replacement was required...
October 6, 2018: International Journal of Colorectal Disease
Jacopo Desiderio, Camille L Stewart, Virginia Sun, Laleh Melstrom, Susanne Warner, Byrne Lee, Hans F Schoellhammer, Vijay Trisal, Benjamin Paz, Yuman Fong, Yanghee Woo
Purpose: Enhanced recovery after surgery (ERAS) protocols for gastric cancer patients have shown improved outcomes in Asia. However, data on gastric cancer ERAS (GC-ERAS) programs in the United States are sparse. The purpose of this study was to compare perioperative outcomes before and after implementation of an GC-ERAS protocol at a National Comprehensive Cancer Center in the United States. Materials and Methods: We reviewed medical records of patients surgically treated for gastric cancer with curative intent from January 2012 to October 2016 and compared the GC-ERAS group (November 1, 2015-October 1, 2016) with the historical control (HC) group (January 1, 2012-October 31, 2015)...
September 2018: Journal of Gastric Cancer
Vittoria Espeli, Stephanie Vergotte, Pierre-Yves Dietrich, Claude Pichard, Marco Siano
To compare safety and effectiveness of prolonged (>28 days) versus short duration (≤28 days) use of nasogastric tube for enteral nutrition and weight loss prevention during curative radiotherapy with or without concurrent chemotherapy or cetuximab for head and neck cancer patients. We performed a retrospective study and database review of all patients at our center, treated with radiotherapy for head and neck cancer receiving enteral nutrition by nasogastric tube. Type of treatment, weight and body mass index changes, and related complications (gastroesophageal reflux, pneumonia, ulcer, feeding tube obstruction, or dislocation) were documented...
October 1, 2018: Nutrition and Cancer
Adam L Jones
This case study presents a patient who has undergone right carotid endarterectomy complicated by glossopharyngeal nerve (or cranial nerve (CN) IX) injury. The patient had one transient ischaemic attack (TIA) three weeks before admission. A computed tomography (CT) scan two days after admission illustrated a right-sided parietal infarct. The patient subsequently had a CT angiogram, which showed a large, calcified plaque in the right internal carotid artery. He then underwent a right carotid endarterectomy...
July 25, 2018: Curēus
James Roger Mcilroy, Niharika Nalagatla, Richard Hansen, Ailsa Hart, Georgina Louise Hold
Background: Interest in the use of faecal microbiota transplantation (FMT) in inflammatory bowel disease (IBD) has increased following outcomes in patients with Clostridioides difficile infection (CDI). While research exploring clinician awareness and attitude towards the use of FMT in CDI has been carried out, data for IBD are currently lacking. Objective: To assess the perceptions of gastroenterologists and current practice relating to FMT as a treatment for IBD in the UK...
October 2018: Frontline Gastroenterology
Teresa K L Boitano, Haller J Smith, Tullia Rushton, Mary C Johnston, Prentiss Lawson, Charles A Leath, Anisa Xhaja, Meredith P Guthrie, J Michael Straughn
OBJECTIVE: To evaluate the impact of enhanced recovery after surgery (ERAS) on postoperative gastrointestinal function in gynecologic oncology patients. METHODS: This retrospective cohort study compared gynecology oncology patients undergoing non-emergent laparotomy from 10/2016 to 6/2017 managed on an ERAS protocol to a control cohort from the year prior to ERAS implementation. Major changes to postoperative care after ERAS implementation included multimodal analgesia, early feeding, goal-directed fluid resuscitation, and early ambulation...
September 20, 2018: Gynecologic Oncology
Sonja Axmann, Karin Hummel, Katharina Nöbauer, Ebrahim Razzazi-Fazeli, Karin Zitterl-Eglseer
Devil's claw is used for the treatment of inflammatory symptoms and degenerative disorders in horses since many years, but without the substantive pharmacokinetic data. The pharmacokinetic parameters of harpagoside, the main active constituent of Harpagophytum procumbens DC ex Meisn., were evaluated in equine plasma after administration of Harpagophytum extract FB 8858 in an open, single-dose, two-treatment, two-period, randomized cross-over design. Six horses received a single dose of Harpagophytum extract, corresponding to 5 mg/kg BM harpagoside, and after 7 days washout period, 10 mg/kg BM harpagoside via nasogastric tube...
September 22, 2018: Journal of Veterinary Pharmacology and Therapeutics
Valentina Decimi, Barbara Parma, Roberto Panceri, Chiara Fossati, Milena Mariani, Silvia Russo, Cristina C Gervasini, Maurizio Cheli, Anna Cereda, Angelo Selicorni
Cornelia de Lange syndrome (CdLS) is a genetic condition characterized by intellectual disability, peculiar facial dysmorphisms, multiorgan malformations, and growth problems. Majority cases of CdLS are caused by mutations in genes of Cohesin pathway. Although feeding problems are a well-known feature, no specific data have been published about the use of nutritional devices. We analyzed use, type, time of introduction, and duration of nutritional devices in 73 CdLS patients. In total, 29/73 (40%) used a device; nasogastric tube (NGT) in 28/73 (38%) and percutaneous endoscopic gastrostomy (PEG) in 7/73 (10%)...
September 2018: American Journal of Medical Genetics. Part A
Samer W El-Kadi, Claire Boutry, Agus Suryawan, Maria C Gazzaneo, Renán A Orellana, Neeraj Srivastava, Hanh V Nguyen, Scot R Kimball, Marta L Fiorotto, Teresa A Davis
Background: Orogastric tube feeding is indicated in neonates with an impaired ability to ingest food normally and can be administered with an intermittent bolus or continuous feeding schedule. Objectives: The objectives were to 1) compare the long-term effect of continuous with intermittent feeding on growth using the newborn pig as a model, 2) determine whether feeding frequency alters lean tissue and fat mass gain, and 3) identify the signaling mechanisms by which protein deposition is controlled in skeletal muscle in response to feeding frequency...
October 1, 2018: American Journal of Clinical Nutrition
Lisa K Lee, Rebekah A Burns, Rajvinder S Dhamrait, Harmony F Carter, Marissa G Vadi, Tristan R Grogan, David A Elashoff, Richard L Applegate, Marc Iravani
BACKGROUND: Hypertrophic pyloric stenosis in infants can cause a buildup of gastric contents. Orogastric tubes (OGTs) or nasogastric tubes (NGTs) are often placed in patients with pyloric stenosis before surgical management to prevent aspiration. However, exacerbation of gastric losses may lead to electrolyte abnormalities that can delay surgery, and placement has been associated with increased risk of postoperative emesis. Currently, there are no evidence-based guidelines regarding OGT/NGT placement in these patients...
September 18, 2018: Anesthesia and Analgesia
Susan McKenzie, Craig Mellis
Introduction: On commencing internship, new medical graduates (new interns) are often required to perform core procedural skills under differing levels of supervision. This variability of knowledge and experience with procedural skills can place patient safety at risk. Consequently, in 2012, we developed a targeted, intensive, 3-day training course for our pre-intern (PrInt) students. The aim of this study was to evaluate the intern preparation package by exploring interns' self-reported knowledge, confidence, and experience in key procedural skills during the early months of internship...
2018: Advances in Medical Education and Practice
Aleš Chrdle, Zdeňka Jerhotová, Michal Vacík, Marek Linka, Václav Chmelík
Alternative modes of antiretroviral administration are sought for people with impaired intestinal passage and/or absorption. We present a case of late HIV diagnosis (CD4+ count 160 cells/µL) with gastric outlet obstruction due to stomach adenocarcinoma. Co-morbidities included oesophageal candidiasis, Helicobacter pylori-positive duodenal ulcers and cytomegalovirus duodenitis. The gastric outlet obstruction required total parenteral nutrition and parenteral medication during four weeks of diagnostic work-up leading to pyloric resection...
September 19, 2018: International Journal of STD & AIDS
Stephan R Vavricka, Henriette Heinrich, Simon Buetikofer, Flavia Breitenmoser, Emanuel Burri, Xiaoye Schneider-Yin, Jasmin Barman-Aksoezen, Luc Biedermann, Michael Scharl, Jonas Zeitz, Gerhard Rogler, Benjamin Misselwitz, Matthias Sauter
Background: Faecal calprotectin correlates with histological and clinical activity in inflammatory bowel disease. Gastrointestinal bleeding might also increase faecal calprotectin levels, erroneously implying intestinal inflammation; however, this possibility has not been systematically assessed. Methods: Sixteen healthy volunteers without gastrointestinal disease and normal faecal calprotectin baseline values ingested their own blood twice, either by drinking or via nasogastric tube...
August 2018: United European Gastroenterology Journal
Sharfuddin Chowdhury, Abdullah Maher Alenazi, Yam Alwi Alharthi
BACKGROUND: Meckel's diverticulum, with an incidence of 2%, is the most common congenital anomaly in the gastrointestinal tract. Its main complications are perforation, obstruction, and bleeding. A few studies have reported that blunt abdominal trauma may result in perforation or obstruction to Meckel's diverticulum. However, reports of significant major intestinal bleeding from Meckel's diverticulum as a complication of blunt abdominal trauma is rare. This paper present what we believe to be the first reported case of significant intestinal bleeding from a Meckel's diverticulum following blunt abdominal trauma...
September 19, 2018: Journal of Medical Case Reports
Ezekiel Wong Toh Yoon
Recurrent aspiration pneumonia can impede the continuation of enteral nutrition. Semi-solid feeds have been demonstrated to reduce the incidence of aspiration pneumonia but are difficult to administer via the nasogastric tube. A novel semi-solidifying enteral formula may be used instead to avoid the occurrence of severe gastroesophageal reflux.
September 2018: Clinical Case Reports
Patrick C Ng, Tara B Hendry-Hofer, Alyssa E Witeof, Matthew Brenner, Sari B Mahon, Gerry R Boss, Vikhyat S Bebarta
Cyanide is a readily available and potentially lethal substance. Oral exposure can result in larger doses, compared withother routes. Currently, there are no antidotes specific for use in the treatment of oral cyanide poisoning, and studies cannotbe done in humans. We report on a new large animal model of oral cyanide toxicity to evaluate potential antidotes. Six femaleswine (Sus scrofa; weight, 45 to 55 kg) were anesthetized, intubated, and instrumented. Animals received a KCN bolusof either 5 or 8 mg/kg delivered via orogastric tube...
September 12, 2018: Comparative Medicine
Ilya M Danelich, John R Bergquist, Whitney J Bergquist, Jennifer L Osborn, Sampaguita S Wright, Brittany J Tefft, Ashley W Sturm, Diana R Langworthy, Jay Mandrekar, Richard M Devine, Scott R Kelley, Kellie L Mathis, John H Pemberton, Adam K Jacob, David W Larson
BACKGROUND: Excessive perioperative fluid administration likely increases postoperative cardiovascular, infectious, and GI complications. Early administration of diuretics after elective surgery facilitates rapid mobilization of excess fluid, potentially leading to decreased bowel edema, more rapid return of bowel function, and reduced length of hospital stay. OBJECTIVE: This study aimed to evaluate the benefit of early diuresis after elective colon and rectal surgery in the setting of an enhanced recovery after surgery practice...
October 2018: Diseases of the Colon and Rectum
Sharon Y Irving, Gina Rempel, Beth Lyman, Wednesday Marie A Sevilla, LaDonna Northington, Peggi Guenter
The placement of a nasogastric tube (NGT) in a pediatric patient is a common practice that is generally perceived as a benign bedside procedure. There is potential risk for NGT misplacement with each insertion. A misplaced NGT compromises patient safety, increasing the risk for serious and even fatal complications. There is no standardized method for verification of the initial NGT placement or reverification assessment of NGT location prior to use. Measurement of the acidity or pH of the gastric aspirate is the most frequently used evidence-based method to verify NGT placement...
September 6, 2018: Nutrition in Clinical Practice
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