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https://www.readbyqxmd.com/read/28227898/automatic-assessment-of-medication-states-of-patients-with-parkinson-s-disease-using-wearable-sensors
#1
Murtadha D Hssayeni, Michelle A Burack, Behnaz Ghoraani, Murtadha D Hssayeni, Michelle A Burack, Behnaz Ghoraani, Behnaz Ghoraani, Michelle A Burack, Murtadha D Hssayeni
Motor fluctuations are a major focus of clinical managements in patients with mid-stage and advance Parkinson's disease (PD). In this paper, we develop a new patient-specific algorithm that can classify those fluctuations during a variety of activities. We extract a set of temporal and spectral features from the ambulatory signals and then introduce a semi-supervised classification algorithm based on K-means and self-organizing tree map clustering methods. Two different types of cluster labeling are introduced: hard and fuzzy labeling...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224256/demonstration-of-two-types-of-fatigue-in-subjects-with-chronic-liver-disease-using-factor-analysis
#2
Ali A Weinstein, Guoqing Diao, Heibatollah Baghi, Carey Escheik, Lynn H Gerber, Zobair M Younossi
PURPOSE: The purpose of this investigation was to determine if it was possible to separate fatigue self-reports into two distinct types of fatigue symptom clusters in research subjects with chronic liver disease (CLD). It was hypothesized that when items from the Medical Outcomes Study Short-Form (SF-36v2) are combined with items from the Fatigue Severity Scale (FSS), these distinct factors will emerge. METHODS: Confirmatory and exploratory factor analyses from data collected in a prospective, natural history study of CLD patients were conducted...
February 21, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28222761/new-evidences-on-the-altered-gut-microbiota-in-autism-spectrum-disorders
#3
Francesco Strati, Duccio Cavalieri, Davide Albanese, Claudio De Felice, Claudio Donati, Joussef Hayek, Olivier Jousson, Silvia Leoncini, Daniela Renzi, Antonio Calabrò, Carlotta De Filippo
BACKGROUND: Autism spectrum disorders (ASDs) are neurodevelopmental conditions characterized by social and behavioural impairments. In addition to neurological symptoms, ASD subjects frequently suffer from gastrointestinal abnormalities, thus implying a role of the gut microbiota in ASD gastrointestinal pathophysiology. RESULTS: Here, we characterized the bacterial and fungal gut microbiota in a cohort of autistic individuals demonstrating the presence of an altered microbial community structure...
February 22, 2017: Microbiome
https://www.readbyqxmd.com/read/28222741/the-impact-of-psychological-factors-on-condition-specific-generic-and-individualized-patient-reported-outcomes-in-low-back-pain
#4
Ida Løchting, Andrew M Garratt, Kjersti Storheim, Erik L Werner, Margreth Grotle
BACKGROUND: An individualized patient reported outcome (PRO) has recently been recommended within LBP research, but no study has evaluated this instrument with commonly applied PROs. Moreover, the impact of psychological factors has mostly been assessed for disease-specific instruments. The objective of this study was to assess the predictive value of illness perceptions, pain catastrophizing and psychological distress on 12 month outcomes assessed by specific, generic and individualized PROs recommended in low back pain (LBP)...
February 21, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28222127/unusual-pattern-of-chikungunya-virus-epidemic-in-the-americas-the-panamanian-experience
#5
Jean-Paul Carrera, Yamilka Díaz, Bernardino Denis, Itza Barahona de Mosca, Dennys Rodriguez, Israel Cedeño, Dimelza Arauz, Publio González, Lizbeth Cerezo, Lourdes Moreno, Lourdes García, Lisseth E Sáenz, María Aneth Atencio, Eddy Rojas-Fermin, Fernando Vizcaino, Nicolas Perez, Brechla Moreno, Sandra López-Vergès, Anayansi Valderrama, Blas Armién
BACKGROUND: Chikungunya virus (CHIKV) typically causes explosive epidemics of fever, rash and polyarthralgia after its introduction into naïve populations. Since its introduction in Panama in May of 2014, few autochthonous cases have been reported; most of them were found within limited outbreaks in Panama City in 2014 and Puerto Obaldia town, near the Caribbean border with Colombia in 2015. In order to confirm that Panama had few CHIKV cases compared with neighboring countries, we perform an epidemiological analysis of chikungunya cases reported from May 2014 to July 2015...
February 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28221187/identification-associated-factors-and-prognosis-of-symptom-clusters-in-taiwanese-patients-with-heart-failure
#6
Tsuey-Yuan Huang, Debra K Moser, Shiow-Li Hwang
BACKGROUND: Patients with heart failure (HF) have multiple distressing symptoms that are associated with poor outcomes. These symptoms do not occur in isolation from each other but likely occur as discrete clusters that may prove helpful to clinicians trying to counsel patients about symptom monitoring and management. Defining common symptom clusters and determining the associations between symptom clusters and outcomes may improve patient management. PURPOSE: The aim of this study was to define symptom clusters and their association with event-free survival in terms of cardiac hospitalization and all-cause mortality in patients with HF...
February 17, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28219788/immersion-in-altered-experience-an-investigation-of-the-relationship-between-absorption-and-psychopathology
#7
REVIEW
Cherise Rosen, Nev Jones, Kayla A Chase, Jennifer K Melbourne, Linda S Grossman, Rajiv P Sharma
Understanding alterations in perceptual experiences as a component of the basic symptom structure of psychosis may improve early detection and the identification of subtle shifts that can precede symptom onset or exacerbation. We explored the phenomenological construct of absorption and psychotic experiences in both clinical (bipolar psychosis and schizophrenia spectrum) and non-clinical participants. Participants with psychosis endorsed significantly higher absorption compared to the non-clinical group. Absorption was positively correlated with all types of hallucinations and multiple types of delusions...
February 17, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28219153/-social-support-and-occupational-stress-relationship-analysis-of-1-413-train-drivers-in-a-railway-bureau
#8
G Z Gu, S F Yu, W H Zhou, H Wu, L Kang, R Chen
Objective: To investigate the social support status of train drivers. Methods: Using cluster sampling, a cross-sectional study was conducted in 1 413 male train drivers (including 301 passenger train drivers, 683 freight train drivers, 85 guest scheduling train drivers, 265 cargo adjustable drivers, and 79 high-speed train drivers) from a railway bureau depot. The survey included individual factors, social support, occupational stressors, strains, personalities, and coping strategy using occupational stress instruments and effort-reward imbalance questionnaire...
February 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28216087/neural-consequences-of-post-exertion-malaise-in-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#9
Dane B Cook, Alan R Light, Kathleen C Light, Gordon Broderick, Morgan R Shields, Ryan J Dougherty, Jacob D Meyer, Stephanie VanRiper, Aaron J Stegner, Laura D Ellingson, Suzanne D Vernon
Post exertion malaise is one of the most debilitating aspects of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, yet the neurobiological consequences are largely unexplored. The objective of the study was to determine the neural consequences of acute exercise using functional brain imaging. Fifteen female Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients and 15 healthy female controls completed 30 minutes of submaximal exercise (70% of peak heart rate) on a cycle ergometer. Symptom assessments (e...
February 16, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28215899/-18-f-fluorodeoxyglucose-positron-emission-tomography-cortical-metabolic-activity-associated-with-distinct-agitation-behaviors-in-alzheimer-disease
#10
Gali H Weissberger, Rebecca J Melrose, Theresa A Narvaez, Dylan Harwood, Mark A Mandelkern, David L Sultzer
OBJECTIVE: This study aimed to investigate the neurobiologic correlates of two distinct clusters of agitation symptoms to identify the unique biologic substrates underlying agitated behaviors. METHODS: Eighty-eight outpatients with mild to moderate Alzheimer disease (AD) were recruited from the VA Greater Los Angeles Healthcare System Geropsychiatry Outpatient Program. A cross-sectional investigation was conducted of the relationship between cerebral glucose metabolism measured via (18)F-fluorodeoxyglucose positron emission tomography and agitated symptoms from the Neuropsychiatric Inventory (NPI) in patients with AD...
January 31, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28215271/effect-of-sleep-extension-on-sluggish-cognitive-tempo-symptoms-and%C3%A2-driving-behavior-in-adolescents-with-chronic-short-sleep
#11
Annie A Garner, Ashley Hansen, Catherine Baxley, Stephen P Becker, Craig A Sidol, Dean W Beebe
OBJECTIVE/BACKGROUND: Few adolescents report obtaining adequate amounts of sleep. Correlational studies have linked adolescent short sleep with driving crashes and sluggish cognitive tempo (SCT), a cluster of symptoms that include sluggishness and low persistence that are related to but distinct from inattention and sleepiness. The relationship between SCT and driving is understudied, and no study has experimentally examined the relationship between SCT and sleep. We examined the relationship between SCT and driving problems in a sample of chronically short-sleeping adolescents...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28215059/motives-for-physical-exercise-participation-as-a-basis-for-the-development-of-patient-oriented-exercise-interventions-in-osteoarthritis-a-cross-sectional-study
#12
Inga Krauss, Uwe Katzmarek, Monika A Rieger, Gorden Sudeck
BACKGROUND: Physical exercises are effective in the treatment of osteoarthritis (OA). There is consensus that exercise interventions should take into account the patient's preferences and needs in order to improve compliance to exercise regimes. One important personal factor is the patient's motivation for physical exercise. Health improvement is a relevant motive for exercise participation. Accordingly, exercise interventions primarily focus on health related needs such as strengthening and pain reduction...
February 17, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28209597/athletic-groin-pain-part-2-a-prospective-cohort-study-on-the-biomechanical-evaluation-of-change-of-direction-identifies-three-clusters-of-movement-patterns
#13
A Franklyn-Miller, C Richter, E King, S Gore, K Moran, S Strike, E C Falvey
BACKGROUND: Athletic groin pain (AGP) is prevalent in sports involving repeated accelerations, decelerations, kicking and change-of-direction movements. Clinical and radiological examinations lack the ability to assess pathomechanics of AGP, but three-dimensional biomechanical movement analysis may be an important innovation. AIM: The primary aim was to describe and analyse movements used by patients with AGP during a maximum effort change-of-direction task. The secondary aim was to determine if specific anatomical diagnoses were related to a distinct movement strategy...
March 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28209309/cluster-headache-and-macroprolactinoma-case-report-of-a-rare-but-potential-important-causality
#14
Lukas Andereggen, Marie-Luise Mono, Frauke Kellner-Weldon, Emanuel Christ
While headache is not an uncommon symptom in patients suffering from pituitary adenomas, cluster headache (CH) has rarely been reported in such cases. Headache associated with hyperprolactinemia has been reported to be responsive to dopamine agonists (DA agonists) in many patients. We report on a patient with refractory CH secondary to a macroprolactinoma who showed immediate and permanent clinical and radiologic recovery following medical treatment with DA agonists. Measurement of prolactin levels in addition to cranial magnetic resonance imaging might be considered in patients with refractory CH, until the significance of this potential causality becomes clearer...
February 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28208885/study-on-distribution-of-scorpions-to-provide-prevention-and-interventions-in-combating-scorpionism-in-poldokhtar-county-lorestan-province-iran
#15
Mansour Nazari, Rastgar Hassan
INTRODUCTION: Scorpions are arthropods of medical importance classified in the class Arachnida, inhabiting hot and dry environments. All scorpions have a venomous sting and several thousand people die each year from scorpion stings, but this mortality is due to the venom of about 25 species located in northern Africa, the Middle East, India, Mexico and parts of South America. Poldokhtar County belongs to one of the southern cities of Lorestan Province, providing suitable habitats for many different species of scorpions due to its specific climatic conditions...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208686/identification-of-autophagy-related-genes-and-their-regulatory-mirnas-associated-with-celiac-disease-in-children
#16
Sergio Comincini, Federico Manai, Cristina Meazza, Sara Pagani, Carolina Martinelli, Noemi Pasqua, Gloria Pelizzo, Marco Biggiogera, Mauro Bozzola
Celiac disease (CD) is a severe genetic autoimmune disorder, affecting about one in 100 people, where the ingestion of gluten leads to damage in the small intestine. Diagnosing CD is quite complex and requires blood tests and intestinal biopsy examinations. Controversy exists regarding making the diagnosis without biopsy, due to the large spectrum of manifesting symptoms; furthermore, small-intestinal gastroscopy examinations have a relatively complex management in the pediatric population. To identify novel molecular markers useful to increase the sensitivity and specificity in the diagnosis of pediatric CD patients, the expression levels of two key autophagy executor genes (ATG7 and BECN1) and their regulatory validated miRNAs (miR-17 and miR-30a, respectively) were analyzed by relative quantitative real-time-PCR on a cohort of confirmed CD patients compared to age-related controls...
February 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28205498/cognitive-control-learning-and-clinical-motor-ratings-are-most-highly-associated-with-basal-ganglia-brain-volumes-in-the-premanifest-huntington-s-disease-phenotype
#17
Maria B Misiura, Spencer Lourens, Vince D Calhoun, Jeffrey Long, Jeremy Bockholt, Hans Johnson, Ying Zhang, Jane S Paulsen, Jessica A Turner, Jingyu Liu, Betul Kara, Elizabeth Fall
OBJECTIVES: Huntington's disease (HD) is a debilitating genetic disorder characterized by motor, cognitive and psychiatric abnormalities associated with neuropathological decline. HD pathology is the result of an extended chain of CAG (cytosine, adenine, guanine) trinucleotide repetitions in the HTT gene. Clinical diagnosis of HD requires the presence of an otherwise unexplained extrapyramidal movement disorder in a participant at risk for HD. Over the past 15 years, evidence has shown that cognitive, psychiatric, and subtle motor dysfunction is evident decades before traditional motor diagnosis...
February 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28203260/yin-cold-or-yang-heat-syndrome-type-of-traditional-chinese-medicine-was-associated-with-the-epidermal-growth-factor-receptor-gene-status-in-non-small-cell-lung-cancer-patients-confirmation-of-a-tcm-concept
#18
Yan-Juan Zhu, Hai-Bo Zhang, Li-Rong Liu, Yi-Hong Liu, Fu-Li Zhang, Jian-Ping Bai, Yong Li, Yan-Chun Qu, Xin Qu, Xian Chen, Yan Li, Shu-Yi Luo, Ai-Hua Ou
Traditional Chinese Medicine (TCM) therapies should be tailored according to the different syndrome types. In order to identify the relationship between the TCM Yin-cold (YC) or Yang-heat (YH) syndrome types and the EGFR gene status, we prospectively studied 310 NSCLC patients. TCM YH or YC was diagnosed by three TCM experts. TCM symptoms and signs were entered into a binary cluster analysis. The relationships between the EGFR gene status, YH or YC syndrome types, and classification by cluster analysis were analyzed using the chi-square test and multivariate logistic regression...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28199719/evidence-that-the-urban-environment-moderates-the-level-of-familial-clustering-of-positive-psychotic-symptoms
#19
Anton Grech, Jim van Os
No abstract text is available yet for this article.
March 1, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28198578/stories-of-change-the-text-analysis-of-handovers-in-an-italian-psychiatric-residential-care-home
#20
M Accordini, E Saita, F Irtelli, M Buratti, G Saluto
: Handovers assure a timely and correct information transfer while socializing workers to the service's culture, however no study describes them as instruments to document organizational change and only a few have focused on psychiatric settings. AIM: To investigate the change in the culture of an Italian psychiatric residential care home as perceived by its Mental Health Workers (MHWs) over the course of two decades. METHOD: Emotional Text Analysis (ETA) was used to analyze the MHWs' handovers completed from 1990 to 2011...
February 15, 2017: Journal of Psychiatric and Mental Health Nursing
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