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https://www.readbyqxmd.com/read/27911239/microvascular-decompression-of-the-cochleovestibular-nerve-for-treatment-of-tinnitus-and-vertigo-a-systematic-review-and-meta-analysis-of-individual-patient-data
#1
Minke J C van den Berge, J Marc C van Dijk, Iris A Posthumus, Nynke Smidt, Pim van Dijk, Rolien H Free
OBJECTIVE Microvascular decompression (MVD) is regarded as a valid treatment modality in neurovascular conflicts (NVCs) causing, for example, trigeminal neuralgia and hemifacial spasms. An NVC of the cochleovestibular nerve might cause tinnitus and/or vertigo; however, general acceptance of MVD for this indication is lacking. The aim of this study was to investigate the effectiveness, safety, and prognostic factors for success of MVD of the cochleovestibular nerve. METHODS A systematic review and meta-analysis of individual patient data (IPD) were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Individual Patient Data (PRISMA-IPD) guidelines...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27908972/clustering-of-health-related-behaviors-among-early-and-mid-adolescents-in-tuscany-results-from-a-representative-cross-sectional-study
#2
Giacomo Lazzeri, Donatella Panatto, Alexander Domnich, Lucia Arata, Andrea Pammolli, Rita Simi, Mariano Vincenzo Giacchi, Daniela Amicizia, Roberto Gasparini
BACKGROUND: A huge amount of literature suggests that adolescents' health-related behaviors tend to occur in clusters, and the understanding of such behavioral clustering may have direct implications for the effective tailoring of health-promotion interventions. Despite the usefulness of analyzing clustering, Italian data on this topic are scant. This study aimed to evaluate the clustering patterns of health-related behaviors. METHODS: The present study is based on data from the Health Behaviors in School-aged Children (HBSC) study conducted in Tuscany in 2010, which involved 3291 11-, 13- and 15-year olds...
December 1, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27908797/molecular-detection-and-characterization-of-respiratory-syncytial-virus-b-genotypes-circulating-in-pakistani-children
#3
Uzma Bashir, Nadia Nisar, Nayab Mahmood, Muhammad Masroor Alam, Hajra Sadia, Syed Sohail Zahoor Zaidi
Respiratory syncytial virus (RSV) is the major cause of acute lower respiratory tract infections in young children, but very little is known about its epidemiology and circulating genotypes in Pakistan. This study analyzed the epidemiological and molecular characteristics of RSV B genotypes in Pakistani children below 5years with acute respiratory tract infections (ARIs) during three consecutive winter seasons from 2010 to 2013. A total of 1941 samples were analyzed for RSV infection by real time PCR and 24% (472/1941) samples were found positive out of which 22...
November 28, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27908796/detection-of-novel-gii-17-norovirus-in-argentina-2015
#4
Juan I Degiuseppe, Karina A Gomes, María F Hadad, Gabriel I Parra, Juan A Stupka
During the winter of 2014-2015 a novel GII.17 norovirus strain emerged as a cause of large gastroenteritis outbreaks in Asia; displacing the long-term predominant strain, GII.4. Although sporadically detected, the emerging GII.17 virus was described in North America and Europe. In this study, we describe the presence of this novel strain in Argentina (South America), and provide new information on the genetic diversity of GII.17 noroviruses. Ten stool samples from individuals (1-88years old; median: 5years old) experiencing gastroenteritis symptoms from San Martín de los Andes, Argentina were tested for Norovirus using RT-PCR...
November 28, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27906034/effect-on-attendance-by-including-focused-information-on-spirometry-in-preventive-health-checks-study-protocol-for-a-randomized-controlled-trial
#5
Lene Maria Ørts, Anders Løkke, Anne-Louise Bjerregaard, Helle Terkildsen Maindal, Annelli Sandbæk
BACKGROUND: Early detection of lung diseases can help to reduce their severity. Lung diseases are among the most frequently occurring and serious diseases worldwide; nonetheless, many patients remain undiagnosed. Preventive health checks including spirometry can detect lung diseases at early stages; however, recruitment for health checks remains a challenge, and little is known about what motivates the attendance. The aim of the study is to examine whether focused information on spirometry in the invitation compared to general information will impact the attendance rate in preventive health checks...
December 1, 2016: Trials
https://www.readbyqxmd.com/read/27906015/validation-of-a-self-reported-hiv-symptoms-list-the-iss-hiv-symptoms-scale
#6
Raffaella Bucciardini, Katherina Pugliese, Daniela Francisci, Andrea Costantini, Elisabetta Schiaroli, Miriam Cognigni, Chiara Tontini, Stefano Lucattini, Luca Fucili, Massimiliano Di Gregorio, Marco Mirra, Vincenzo Fragola, Sara Pompili, Rita Murri, Stefano Vella
BACKGROUND: To describe the development and the psychometric properties of the Istituto Superiore di Sanità-HIV symptoms scale (lSS-HIV symptoms scale). METHODS: The ISS-HIV symptom scale was developed by an Italian working team including researchers, physicians and people living with HIV. The development process went through the following steps: (1) review of HIV/AIDS literature; (2) focus group; (3) pre-test analysis; (4) scale validation. RESULTS: The 22 symptoms of HIV-ISS symptoms scale were clustered in five factors: pain/general discomfort (7 items); depression/anxiety (4 items); emotional reaction/psychological distress (5 items); gastrointestinal discomfort (4 items); sexual discomfort (2 items)...
April 9, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27903282/start-now-a-comprehensive-skills-training-programme-for-female-adolescents-with-oppositional-defiant-and-conduct-disorders-study-protocol-for-a-cluster-randomised-controlled-trial
#7
Linda Kersten, Martin Prätzlich, Sandra Mannstadt, Katharina Ackermann, Gregor Kohls, Helena Oldenhof, Daniel Saure, Katrin Krieger, Beate Herpertz-Dahlmann, Arne Popma, Christine M Freitag, Robert L Trestman, Christina Stadler
BACKGROUND: In Europe, the number of females exhibiting oppositional defiant disorder (ODD) and conduct disorder (CD) is growing. Many of these females live in youth welfare institutions. Consequently, there is a great need for evidence-based interventions within youth welfare settings. A recently developed approach targeting the specific needs of girls with ODD and CD in residential care is START NOW. The aim of this group-based behavioural skills training programme is to specifically enhance emotional regulation capacities to enable females with CD or ODD to appropriately deal with daily-life demands...
December 1, 2016: Trials
https://www.readbyqxmd.com/read/27902865/small-world-properties-changes-in-mild-traumatic-brain-injury
#8
Yongxia Zhou
PURPOSE: To investigate local and global efficiency changes characterized by small-world properties based on resting-state functional MRI, such as centrality and clustering coefficient, in mild traumatic brain injury (MTBI) patients; and to associate these findings with axonal injury as measured by diffusion tensor imaging (DTI) as well as with post-concussive symptom (PCS). MATERIALS AND METHODS: Thirty patients (mean age 35 ± 13 years) with clinically defined MTBI and 45 age-matched healthy controls (mean age 37 ± 10 years) participated in the experiments...
November 30, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27896984/methods-for-clustering-time-series-data-acquired-from-mobile-health-apps
#9
Nicole Tignor, Pei Wang, Nicholas Genes, Linda Rogers, Steven G Hershman, Erick R Scott, Micol Zweig, Yu-Feng Yvonne Chan, Eric E Schadt
In our recent Asthma Mobile Health Study (AMHS), thousands of asthma patients across the country contributed medical data through the iPhone Asthma Health App on a daily basis for an extended period of time. The collected data included daily self-reported asthma symptoms, symptom triggers, and real time geographic location information. The AMHS is just one of many studies occurring in the context of now many thousands of mobile health apps aimed at improving wellness and better managing chronic disease conditions, leveraging the passive and active collection of data from mobile, handheld smart devices...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27893884/effect-of-the-goals-of-care-intervention-for-advanced-dementia-a-randomized-clinical-trial
#10
Laura C Hanson, Sheryl Zimmerman, Mi-Kyung Song, Feng-Chang Lin, Cherie Rosemond, Timothy S Carey, Susan L Mitchell
Importance: In advanced dementia, goals of care decisions are challenging and medical care is often more intensive than desired. Objective: To test a goals of care (GOC) decision aid intervention to improve quality of communication and palliative care for nursing home residents with advanced dementia. Design, Setting, and Participants: A single-blind cluster randomized clinical trial, including 302 residents with advanced dementia and their family decision makers in 22 nursing homes...
November 28, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27893485/peripheral-neuropathic-pain-a-mechanism-related-organizing-principle-based-on-sensory-profiles
#11
Ralf Baron, Christoph Maier, Nadine Attal, Andreas Binder, Didier Bouhassira, Giorgio Cruccu, Nanna B Finnerup, Maija Haanpää, Per Hansson, Philipp Hüllemann, Troels S Jensen, Rainer Freynhagen, Jeffrey D Kennedy, Walter Magerl, Tina Mainka, Maren Reimer, Andrew S C Rice, Märta Segerdahl, Jordi Serra, Sören Sindrup, Claudia Sommer, Thomas Tölle, Jan Vollert, Rolf-Detlef Treede
Patients with neuropathic pain are heterogeneous in etiology, pathophysiology and clinical appearance. They exhibit a variety of pain-related sensory symptoms and signs (sensory profile). Different sensory profiles might indicate different classes of neurobiological mechanisms and hence subgroups with different sensory profiles might respond differently to treatment.The aim of the investigation was to identify subgroups in a large sample of neuropathic pain patients using hypothesis-free statistical methods on the database of three large multi-national research networks (German Research Network on Neuropathic Pain (DFNS), IMI-Europain, Neuropain)...
November 3, 2016: Pain
https://www.readbyqxmd.com/read/27890947/profile-of-pneumocystis-infection-in-a-tertiary-care-institute-in-north-india
#12
Ravinder Kaur, Pragyan Swagatika Panda, Richa Dewan
CONTEXT: Pneumocystis jirovecii pneumonia (PcP) is still remains a common opportunistic disease in human immunodeficiency virus (HIV) infected individuals. Study on PcP in developing countries are scarce. AIMS: To study the occurrence of P. jirovecii infection in clinically suspected individuals in a tertiary care institute. SETTINGS AND DESIGN: Retrospective study conducted in a tertiary care hospital. MATERIALS AND METHODS: Two years data regarding respiratory sample analysis, HIV status, and cluster of differentiation 4 (CD4) cell count of clinically suspected pneumocystis infection patients with known/unknown HIV status were analyzed...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27889937/household-level-risk-factors-for-secondary-influenza-like-illness-in-a-rural-area-of-bangladesh
#13
Anne M Weaver, Kaniz Khatun-E-Jannat, Emily Cercone, Kimberly Krytus, Badrul Munir Sohel, Makhdum Ahmed, Mustafizur Rahman, Eduardo Azziz-Baumgartner, Jihnhee Yu, Alicia M Fry, Stephen P Luby, Pavani K Ram
OBJECTIVE: To describe household-level risk factors for secondary Influenza-like illness (ILI), an important public health concern in the low-income population of Bangladesh. METHODS: Secondary analysis of control participants in a randomized controlled trial evaluating the effect of handwashing to prevent household ILI transmission. We recruited index-case patients with ILI-fever (<5 years); fever, cough or sore throat (≥5 years)-from health facilities, collected information on household factors, and conducted syndromic surveillance among household contacts for 10 days after resolution of index-case patients' symptoms...
November 27, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27888723/deconstructing-bipolar-disorder-and-schizophrenia-a-cross-diagnostic-cluster-analysis-of-cognitive-phenotypes
#14
Junghee Lee, Shemra Rizzo, Lori Altshuler, David C Glahn, David J Miklowitz, Catherine A Sugar, Jonathan K Wynn, Michael F Green
BACKGROUND: Bipolar disorder (BD) and schizophrenia (SZ) show substantial overlap. It has been suggested that a subgroup of patients might contribute to these overlapping features. This study employed a cross-diagnostic cluster analysis to identify subgroups of individuals with shared cognitive phenotypes. METHOD: 143 participants (68 BD patients, 39 SZ patients and 36 healthy controls) completed a battery of EEG and performance assessments on perception, nonsocial cognition and social cognition...
November 19, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27888680/symptomatic-and-functional-outcomes-of-substance-use-disorder-persistence-2-years-after-admission-to-a-first-episode-psychosis-program
#15
Amal Abdel-Baki, Clairélaine Ouellet-Plamondon, Émilie Salvat, Kawthar Grar, Stéphane Potvin
Substance use disorders (SUD) in first-episode psychosis (FEP) are highly prevalent and linked with poor outcomes. However, most longitudinal studies investigating their impacts in FEP have not reported proportions of patients who ceased SUD. Our aim was to examine the influence of SUD course on functional and symptomatic outcomes as well as service use in FEP. We performed a 2-year longitudinal study of 212 FEP patients, aged between 18 and 30 years, admitted to 2 early psychosis services in Montréal, Québec, Canada...
November 10, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27886792/diagnosis-and-management-of-endomyocardial-fibrosis
#16
REVIEW
Andrea Beaton, Ana Olga Mocumbi
Endomyocardial fibrosis (EMF) remains an important cause of restrictive cardiomyopathy worldwide. Patients cluster in specific geographic locations and are almost universally living in extreme poverty. Specific etiology remains elusive and is likely multifactorial. Untreated EMF has a very poor prognosis. Medical management can mitigate symptoms for a time but has no curative benefit. Early surgical interventions may improve survival but are not readily available in most EMF-endemic regions. Increased awareness, advocacy, and research are needed to further understand this neglected tropical cardiomyopathy and to improve survival of those affected...
February 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/27886368/written-information-for-patients-or-parents-of-child-patients-to-reduce-the-use-of-antibiotics-for-acute-upper-respiratory-tract-infections-in-primary-care
#17
REVIEW
Jack W O'Sullivan, Robert T Harvey, Paul P Glasziou, Amanda McCullough
BACKGROUND: Acute upper respiratory tract infections (URTIs) are frequently managed in primary care settings. Although many are viral, and there is an increasing problem with antibiotic resistance, antibiotics continue to be prescribed for URTIs. Written patient information may be a simple way to reduce antibiotic use for acute URTIs. OBJECTIVES: To assess if written information for patients (or parents of child patients) reduces the use of antibiotics for acute URTIs in primary care...
November 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27881136/community-health-workers-adherence-to-referral-guidelines-evidence-from-studies-introducing-rdts-in-two-malaria-transmission-settings-in-uganda
#18
Sham Lal, Richard Ndyomugenyi, Lucy Paintain, Neal D Alexander, Kristian S Hansen, Pascal Magnussen, Daniel Chandramohan, Siân E Clarke
BACKGROUND: Many malaria-endemic countries have implemented national community health worker (CHW) programmes to serve remote populations that have poor access to malaria diagnosis and treatment. Despite mounting evidence of CHWs' ability to adhere to malaria rapid diagnostic tests (RDTs) and treatment guidelines, there is limited evidence whether CHWs adhere to the referral guidelines and refer severely ill children for further management. In southwest Uganda, this study examined whether CHWs referred children according to training guidelines and described factors associated with adherence to the referral guideline...
November 24, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27879960/effectiveness-of-music-based-interventions-on-motricity-or-cognitive-functioning-in-neurological-populations-a-systematic-review
#19
Lousin Moumdjian, Teppo Sarkamo, Carmela Leone, Marc Leman, Peter Feys
INTRODUCTION: Motor and cognitive symptoms are frequent in persons with neurological disorders and often require extensive long-term rehabilitation. Recently, a variety of musicbased interventions have been introduced into neurological rehabilitation as training tools. AIM: This review aims to a) describe and define music-based intervention modalities and content which are applied in experimental studies, and b) describe the effects of these interventions on motor and/or cognitive symptoms in the neurological population...
November 23, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27878907/from-childhood-trauma-to-self-harm-an-investigation-of-theoretical-pathways-among-female-prisoners
#20
Ruth Howard, Thanos Karatzias, Kevin Power, Adam Mahoney
BACKGROUND: Despite empirical evidence suggesting complex associations between childhood trauma and self-harm, there is a dearth of research investigating this association in the female prison population. The current study explored pathways to self-harm following childhood trauma, by investigating the mediating roles of Post-traumatic Stress Disorder (PTSD) symptoms, emotion regulation and dissociation, in this relationship, within a sample of 89 female prisoners. METHODS: Cross-sectional, interview-format, questionnaire study within a female prison population...
November 22, 2016: Clinical Psychology & Psychotherapy
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