Xiaoyan Tang, Dezheng Chen, Ling Zhang, Ping Fu, Yanxia Chen, Zhou Xiao, Xiangcheng Xiao, Weisheng Peng, Li Cheng, Yanmin Zhang, Hongbo Li, Kehui Li, Bizhen Gou, Xin Wu, Qian Yu, Lijun Jian, Zaizhi Zhu, Yu Wen, Cheng Liu, Hen Xue, Hongyu Zhang, Xin He, Bin Yan, Liping Zhong, Bin Huang, Mingying Mao
OBJECTIVES: Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding. The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation (RCA) combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis (IHD) treatment. METHODS: Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments, and were randomly divided into RCA group and saline flushing group...
November 15, 2022: Journal of Zhejiang University. Science. B