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"BiPap" OR "BPap" OR "Bilevel Positive Airway Pressure" OR "Bi-Level Positive Airway Pressure" OR "IPAP" OR "EPAP"

Killen Harold Briones-Claudett, Antonio Esquinas Rodriguez, Mónica H Briones-Claudett, Miguel Puga-Tejada, Mariuxi Del Pilar Cabrera Baños, Christian Roberto Pazmiño Dueñas, Carlos Israel Torres Herrera, Michelle Grunauer
BACKGROUND: This study was designed to determine the results associated with the use of noninvasive mechanical ventilation (NIV) using the BiPAP S/T-AVAPS ventilation strategy in subjects with mild to moderate de novohypoxaemicrespiratory failure. METHODS: This is a prospective study that includes subjects with de novohypoxaemic respiratory failure (not produced by acute exacerbations of COPD, chronic lung disease, or congestive heart failure) with mild to moderate PaO₂/FiO₂, who were admitted to the Intensive Care Unit (ICU) of Santa Maria Clinic in Guayaquil, Ecuador...
October 14, 2018: Anaesthesiology Intensive Therapy
Tianzhu Guan, Yonghai Sun, Tiezhu Li, Ligang Hou, Jie Zhang, Yongjun Wang
Human exposure to bisphenol compounds (BPs) has been implicated in the development of several chronic diseases. Instead of exploiting the traditional methods for determination of BPs, this work confirms that the human estrogen receptor α ligand binding domain (hERα-LBD) is a powerful recognition element that can be used to monitor multi-residue of BPs in urine samples by fluorescence polarization (FP) assay. Test parameters were optimized for the best performance. Under the optimal conditions, the IC50 values of BPs are in the range of 0...
October 11, 2018: Biotechnology and Applied Biochemistry
Yaxuan Liu, Yangyang Ying, Jaffar S Pandu, Yan Wang, Shuang Dou, Yanzhong Li, Dedong Ma
OBJECTIVE: We have designed the expiratory positive airway pressure (EPAP) mask to provide a new sort of therapeutic strategies for Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS). And this study aims to assess the safety, efficacy and compliance of the EPAP therapy. METHODS: 40 healthy volunteers were enrolled to measure the end-tidal carbon dioxide pressure (PETCO2 ) while being treated by EPAP mask. 40 symptomatic moderate or severe OSAHS patients (AHI≥15/h) recruited were equally divided into two groups randomly and treated with CPAP or mask for a week respectively...
September 24, 2018: Auris, Nasus, Larynx
Rosita Diana, Ugo Caruso, Simona Concilio, Stefano Piotto, Angela Tuzi, Barbara Panunzi
Currently considerable research both in life and in environmental sciences is dedicated to chemosensors able to detect metals of biological interest such as zinc and iron or other toxic and carcinogenic, as cadmium, mercury, chromium, lead. Recently, a new chemosensor strategy of "single chemosensor for multiple metals" has emerged. For this scope, many fluorescent sensors for Cd(II) and Zn(II) have been designed and synthetized, as ligand systems or in polymeric matrices [1], [2], [3]. The data presented in this article include experimental data on the of a pyridyl/phenolic/benzothiazole functionalized colorimetric receptor ( BPAP ) and its selectively recognise Fe(III) and Fe(II) ions with visible, naked eye colour changes and fluorometric selectivity towards Zn2+ and Cd2+ ions in aqueous medium...
August 2018: Data in Brief
Rachel Edmiston, Stuart Wilkinson, Simon Jones, Karen Tylee, Alexander Broomfield, Iain A Bruce
BACKGROUND: Inclusion cell disease (I-cell) is a rare autosomal recessive metabolic disease involving multiple organ systems, associated with a severely restricted life expectancy. No curative therapy is currently available, with management aimed at symptom palliation. METHODS: We present a retrospective, single-centre, case series of children referred to a tertiary paediatric metabolic service. The clinical presentation, demographics, genetics and natural history of the condition are investigated...
September 13, 2018: JIMD Reports
Yusuke Mon, Chisato Tamaki
Patients with lateral medullary infarction (LMI) sometimes present with respiratory failure in the acute or subacute phase. We experienced a LMI patient with progression of respiratory failure that required bilevel positive airway pressure in the chronic phase. LMI patients must be carefully observed even in the chronic phase of recovery.
August 2018: Clinical Case Reports
María Teresa Abeleira, Jacobo Limeres, Mercedes Outumuro, Paula Sofía Vidal, Marcio Diniz-Freitas, Manuel Ruíz-Piñón, Pedro Diz
This case report involves a 10-year-old boy diagnosed with spinal muscular atrophy type 2 who underwent nighttime mechanical ventilation with bi-level positive airway pressure. The oral examination revealed restricted mouth opening, lip interposition, dental crowding and maxillary compression. After maxillary expansion the upper airway volume increased 18.6%; 13 episodes of airway infections (20 days of hospitalization) were recorded in the 2 years prior to the maxillary expansion and only 4 episodes (no hospital admissions) in the 2 subsequent years...
August 23, 2018: American Journal of Physical Medicine & Rehabilitation
Hanna Hong, Rory Kamerman-Kretzmer, Roberta Kato, Tena Rosser, Michele VanHirtum-Das, Sally L Davidson Ward
There have been no published reports of central respiratory control abnormalities in pediatric patients with UNC80 or KCNJ11 mutations which cause neurologic channelopathies. We describe an 8-year-old male with a pathogenic UNC80 mutation, intellectual disability, hypotonia and epilepsy with severe central sleep apnea (213.5 events/h) on polysomnography (PSG). We also describe a 20-month-old female with a KCNJ11 mutation, neonatal diabetes and developmental delay who had severe central sleep apnea (131.1 events/h)...
August 15, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Xuan Xiao, Junyu Li, Tong Yu, Lei Zhou, Xiaolin Fan, Han Xiao, Yue Wang, Lei Yang, Junhui Lv, Xiaojing Jia, Zhaobin Zhang
A recent increase in the use of bisphenol A (BPA) alternatives to manufacture plastics has led to safety concerns. Here, we evaluated the estrogenic and anti-estrogenic activities of bisphenol AP (BPAP), a poorly studied BPA alternative, using in vitro, in vivo and in silico tools. BPAP exhibited weak estrogenicity but strong anti-estrogenicity (IC50  = 2.35 μM) in a GeneBLAzer™ β-lactamase reporter gene assay. BPAP, when administered alone or in combination with E2 (50 μg kg-1 bw d-1 ) for 3 d, significantly decreased the uterine weights of post-weaning CD-1 mice at doses of 10 mg kg-1 bw d-1 and higher...
November 2018: Environmental Pollution
Nishad Khamankar, Grant Coan, Barry Weaver, Cassie S Mitchell
Objective: It is hypothesized earlier non-invasive (NIV) ventilation benefits Amyotrophic Lateral Sclerosis (ALS) patients. NIV typically consists of the removable bi-level positive airway pressure (Bi-PAP) for adjunctive respiratory support and/or the cough assist intervention for secretion clearance. Historical international standards and current USA insurance standards often delay NIV until percent predicted forced vital capacity (FVC %predict) is <50. We identify the optimal point for Bi-PAP initiation and the synergistic benefit of daily Bi-PAP and cough assist on associative increases in survival duration...
2018: Frontiers in Neurology
Yi-Ting Hsieh, Tai-Ying Lee, Jui-Shih Kao, Hsin-Lin Hsu, Chee-Fah Chong
Acute pulmonary edema due to sympathetic surge and increased peripheral vascular resistance often present to the emergency department (ED) with markedly elevated blood pressure, severe dyspnea, and desaturation. This condition is known as "SCAPE" (sympathetic crashing acute pulmonary edema). We present three SCAPE patients who were successfully treated with high-dose nitroglycerin (NTG) and bilevel positive airway pressure (BiPAP) ventilation. All three patients presented with respiratory failure on arrival but rapidly improved after treatment and did not require endotracheal intubation or admission to the intensive care unit (ICU)...
March 2018: Turkish Journal of Emergency Medicine
Luis Perez-Baena, Martí Pons-Òdena
No abstract text is available yet for this article.
July 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
H J Liu, N Zhao, A F Zhang
Objective: To study the relationship between symptoms and sleep staging in OSAHS patients. Method: A cross-sectional study. Adult subjects who attended a sleep laboratory for diagnostic polysomnography for a period of 1 month were recruited consecutively.OSAHS was diagnosed using American Academy of Sleep Medicine criteria.Subjects filled a questionnaire for symptoms prior to polysomnography. Result: Thirty subjects, of whom 83.3% were obese, met diagnostic criteria, with males constituting 46.7% and females constituting 53%...
November 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Susan A Kayser, Catherine A VanGilder, Elizabeth A Ayello, Charlie Lachenbruch
OBJECTIVE: To examine the prevalence and characteristics of medical device-related pressure injuries (MDR PIs) in a large, generalizable database. METHODS: This study is a retrospective analysis of the 2016 International Pressure Ulcer Prevalence data. Data were limited to US and Canadian facilities. Facilities included acute care, long-term care, rehabilitation, long-term acute care hospitals, and hospice. Analysis included 102,865 adult patients; 99,876 had complete data and were the focus of the analysis and are reported in the results below...
June 2018: Advances in Skin & Wound Care
Nash S Moawad, Estefania Santamaria Flores, Linda Le-Wendling, Martina T Sumner, F Kayser Enneking
BACKGROUND: Laparoscopic hysterectomies comprise a large proportion of all hysterectomies in the United States. Procedures completed under regional anesthesia pose a number of benefits to patients, but laparoscopic hysterectomies traditionally have been performed under general anesthesia. We describe a case of total laparoscopic hysterectomy under epidural anesthesia with the patient fully awake. CASE: A 51-year-old woman with abnormal uterine bleeding underwent an uncomplicated total laparoscopic hysterectomy, bilateral salpingectomy, and excision of endometriosis...
June 2018: Obstetrics and Gynecology
Nilam Danish, Imran S Khawaja, Carlos H Schenck
A case is reported of recurrent, injurious self-biting during sleep, requiring surgical interventions, in a 55-year-old obese man with a 20-year history of violent complex parasomnia, with greatly increased frequency and severity of episodes induced by work stress during the preceding 3 years. After clinical evaluation and overnight, hospital-based video-polysomnography, the cause of the chronic injurious parasomnia was deemed to be a non-rapid eye movement (NREM) sleep parasomnia comorbid with severe obstructive sleep apnea...
May 15, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Lili Guan, Weiliang Wu, Yating Huo, Xiaoying Li, Bingpeng Guo, Yuqiong Yang, Jiawen Xu, Fangfang Jiang, Luqian Zhou, Rongchang Chen
INTRODUCTION: Obesity hypoventilation syndrome (OHS) is a major respiratory complication caused by severe obesity, being associated with significant morbidity, negative impacts on quality of life and reduced survival if not treated appropriately. Positive airway pressure therapy is the first-line treatment for OHS although the optimal modality remains unclear. The goal of this study is to identify the efficacy of home bilevel positive airway pressure therapy by comparison to continuous positive airway pressure therapy and determine the best strategy for patients with OHS...
May 3, 2018: BMJ Open
Sara Mota, Liuba Germanova, Joana Cortesão, Teresa Paiva
INTRODUCTION: Duchenne muscular dystrophy (DMD) is an x linked recessive disorder. Long term prognosis is ominous, with development of respiratory distress and cardiomyopathy in advanced stage of the disease and expected death in the teens-to-mid 20s due to respiratory or cardiac failure. Peri-operative management of this patients is challenging due to difficult airway anatomy (macroglossia, limited neck and mandibular mobility). Additionally, they are at risk of developing malignant hyperthermia, rhabdomyolysis and hyperkalemic cardiac arrest when exposed to halogenated inhalational anaesthetics and depolarizing muscle relaxants...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
C da L Goulart, E A San Martin, K M K Mansour, P B Schneiders, A L G da Silva
The aim of this study was to evaluate the effect of expiratory positive airway pressure (EPAP) on heart rate variability (HRV) indices at rest and during 6-min walk test (6MWT) in chronic obstructive pulmonary disease (COPD) patients. Fifteen moderate to severe COPD patients were randomized and evaluated with and without (Non-EPAP) a 5 cmH2O EPAP device. Respiratory rate (RR) was collected at rest (5 min), during the 6MWT (5 min), and at recovery (5 min). Indices of HRV were computed in the time domain, in the frequency domain, and nonlinear analysis...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
Xiaoli Sun, Junyu Peng, Muhua Wang, Jincheng Wang, Chunlan Tang, Luoxing Yang, Hua Lei, Fang Li, Xueli Wang, Jiping Chen
This paper describes the determination of bisphenol A (BPA), bisphenol S (BPS), bisphenol F (BPF), bisphenol E (BPE), bisphenol B (BPB), bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol Z (BPZ) and tetrabromobisphenol A (TBBPA) in sewage and sludge samples. A highly class-selective dummy molecularly imprinted polymer was used for solid phase extraction (SPE) and clean-up of the samples. Bisphenols was quantified by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The developed method had acceptable recoveries (43...
June 1, 2018: Journal of Chromatography. A
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