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"CPAP" OR "Continuous Positive Airway Pressure"

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https://www.readbyqxmd.com/read/30551233/impact-of-time-to-neonatal-transport-on-outcomes-of-transient-tachypnea-of-the-newborn
#1
Katsuya Hirata, Masatoshi Nozaki, Narutaka Mochizuki, Shinya Hirano, Kazuko Wada
OBJECTIVE:  To assess effects of neonatal transport on transient tachypnea of the newborn (TTN) in outborn term neonates. STUDY DESIGN:  This retrospective cohort study included 66 term neonates diagnosed with TTN and transported to the Osaka Women's and Children's Hospital neonatal intensive care unit between January 2003 and March 2018. A multivariate logistic regression analysis identified perinatal and neonatal transport factors associated with adverse short-term outcomes defined as mechanical ventilation >48 hours, continuous positive airway pressure >72 hours, pulmonary hemorrhage, and requirement for inhaled nitric oxide, thoracentesis, or surfactant replacement therapy...
December 14, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/30551223/cpap-does-not-reduce-inflammatory-biomarkers-in-patients-with-coronary-artery-disease-and-nonsleepy-obstructive-sleep-apnea-a-randomized-controlled-trial
#2
Erik Thunström, Helena Glantz, Tülay Yucel-Lindberg, Kristin Lindberg, Mustafa Saygin, Yüksel Peker
No abstract text is available yet for this article.
December 14, 2018: Sleep
https://www.readbyqxmd.com/read/30550176/-effect-of-butylphthalide-on-oxidative-stress-and-cognitive-function-in-old-obstructive-sleep-apnea-hypopnea-syndrome-patients
#3
P P Zhang, Y H Wang, X Q Han, C Huang, Y L Ge, Y Wang, Y N Zhao, L Wang, J H Wang, H Y Wang
Objective: To explore the effect of butylphthalide on oxidative stress and cognitive function in old obstructive sleep apnea hypopnea syndrome (OSAHS)patients. Method: A total of 90 old OSAHS patients with cognitive impairment were choosed with Polysomnography(PSG). By random number table method OSAHS patients were randomly divided into non-invasive ventilator group ( n =30), butylphthalide with non-invasive ventilator group( n =30) and treatment group of butylphthalide( n =30). Non-invasive ventilator group was given continuous positive airway pressure treatment for three months, butylphthalide with non-invasive ventilator group accepted oral butylphthalide therapy and continuous positive airway pressure treatment for three months, treatment group of butylphthalide only accepted oral butylphthalide therapy for three months...
September 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/30549161/validation-of-collaborate-and-sure-two-short-questionnaires-to-measure-shared-decision-making-during-cpap-initiation
#4
Anders Broström, Amir H Pakpour, Per Nilsen, Berith Hedberg, Martin Ulander
Adherence to continuous positive airway pressure (CPAP) treatment tends to be low. Brief validated instruments focusing on shared decision making have not been used in a CPAP context. The aim was to investigate factorial structure, categorical functioning of the response scale and differential item functioning across sub-populations of the CollaboRATE and Sure questionnaires among patients with obstructive sleep apnea (OSA) before CPAP treatment is initiated. A prospective design, including 193 objectively diagnosed (polygraphy) OSA patients (68% men, 59...
December 13, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/30544030/large-posterior-lingual-thyroglossal-duct-cyst-pneumatically-splinted-with-auto-continuous-positive-airway-pressure-at-low-pressures
#5
Romy Hoque, Donald L Bliwise
No abstract text is available yet for this article.
October 19, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/30539239/risk-of-clinically-relevant-pericardial-effusion-after-pediatric-cardiac-surgery
#6
Rik Adrichem, Saskia Le Cessie, Mark G Hazekamp, Nicolette A M Van Dam, Nico A Blom, Lukas A J Rammeloo, Luc H P M Filippini, Irene M Kuipers, Arend D J Ten Harkel, Arno A W Roest
Pericardial effusion (PE) after pediatric cardiac surgery is common. Because of the lack of a uniform classification of the presence and severity of PE, we evaluated PE altering clinical management: clinically relevant PE. Risk factors for clinically relevant PE were studied. After cardiac surgery, children were followed until 1 month after surgery. Preoperative variables were studied in the complete cohort. Perioperative and postoperative variables were studied in a case-control manner. Patients with and without clinically relevant PE were matched on age, gender, and diagnosis severity in a 1:1 ratio...
December 11, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/30538163/positive-airway-pressure-for-sleep-disordered-breathing-in-acute-quadriplegia-a-randomised-controlled-trial
#7
David J Berlowitz, Rachel Schembri, Marnie Graco, Jacqueline M Ross, Najib Ayas, Ian Gordon, Bonne Lee, Allison Graham, Susan V Cross, Martin McClelland, Paul Kennedy, Pradeep Thumbikat, Cynthia Bennett, Andrea Townson, Timothy J Geraghty, Sue Pieri-Davies, Raj Singhal, Karen Marshall, Deborah Short, Andrew Nunn, Duncan Mortimer, Doug Brown, Robert J Pierce, Peter A Cistulli
RATIONALE: Highly prevalent and severe sleep-disordered breathing caused by acute cervical spinal cord injury (quadriplegia) is associated with neurocognitive dysfunction and sleepiness and is likely to impair rehabilitation. OBJECTIVE: To determine whether 3 months of autotitrating CPAP would improve neurocognitive function, sleepiness, quality of life, anxiety and depression more than usual care in acute quadriplegia. METHODS AND MEASUREMENTS: Multinational, randomised controlled trial (11 centres) from July 2009 to October 2015...
December 11, 2018: Thorax
https://www.readbyqxmd.com/read/30538069/nasal-function-and-cpap-compliance
#8
Akiko Inoue, Shintaro Chiba, Kentaro Matsuura, Hiroshi Osafune, Robson Capasso, Kota Wada
OBJECTIVE: Continuous positive airway pressure (CPAP) is the mainstay therapy for patients with obstructive sleep apnea (OSA) however compliance with CPAP is variable. Nasal ailments, such as nasal congestion are frequently mentioned as a cause for CPAP non-compliance, and potentially could be addressed prior to CPAP initiation, however, no specific criteria or recommendations for the evaluation and management of these patients exist. The aim of this retrospective study is to evaluate the effects of nasal anatomic features and disease on adherence to CPAP therapy for patients with OSA and determine the indications for pre-CPAP nasal treatment by using data obtained at clinical examination...
December 8, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/30531535/optimizing-respiratory-management-in-resource-limited-settings
#9
Rebecca Inglis, Emmanuel Ayebale, Marcus J Schultz
PURPOSE OF REVIEW: This review focuses on the emerging body of literature regarding the management of acute respiratory failure in low- and middle-income countries (LMICs). The aim is to abstract management principles that are of relevance across a variety of settings where resources are severely limited. RECENT FINDINGS: Mechanical ventilation is an expensive intervention associated with considerable mortality and a high rate of iatrogenic complications in many LMICs...
December 5, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/30530478/inhibition-of-cpap-tubulin-interaction-prevents-proliferation-of-centrosome-amplified-cancer-cells
#10
Aruljothi Mariappan, Komal Soni, Kenji Schorpp, Fan Zhao, Amin Minakar, Xiangdong Zheng, Sunit Mandad, Iris Macheleidt, Anand Ramani, Tomáš Kubelka, Maciej Dawidowski, Kristina Golfmann, Arpit Wason, Chunhua Yang, Judith Simons, Hans-Günther Schmalz, Anthony A Hyman, Ritu Aneja, Roland Ullrich, Henning Urlaub, Margarete Odenthal, Reinhardt Büttner, Haitao Li, Michael Sattler, Kamyar Hadian, Jay Gopalakrishnan
Centrosome amplification is a hallmark of human cancers that can trigger cancer cell invasion. To survive, cancer cells cluster amplified extra centrosomes and achieve pseudobipolar division. Here, we set out to prevent clustering of extra centrosomes. Tubulin, by interacting with the centrosomal protein CPAP, negatively regulates CPAP-dependent peri-centriolar material recruitment, and concurrently microtubule nucleation. Screening for compounds that perturb CPAP-tubulin interaction led to the identification of CCB02, which selectively binds at the CPAP binding site of tubulin...
December 10, 2018: EMBO Journal
https://www.readbyqxmd.com/read/30529774/continuous-positive-airway-pressure-for-adults-with-obstructive-sleep-apnea-and-cardiovascular-disease-a-meta-analysis-of-randomized-trials
#11
Felipe da Silva Paulitsch, Linjie Zhang
BACKGROUND: It remains uncertain whether continuous positive airway pressure (CPAP) therapy would significantly impact hard clinical outcomes in patients with obstructive sleep apnea (OSA). This meta-analysis aimed to assess the effects of CPAP in survival and secondary prevention of major cardiovascular events in patients with OSA and cardiovascular disease (CVD). METHODS: PubMed, Cochrane CENTRAL, LILACS, and SciElo databases (up to January 2018) were searched for randomized trials that compared CPAP with no active treatment in adults with OSA and CVD...
October 30, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/30529484/efficacy-of-bilevel-ventilatory-support-in-the-treatment-of-stable-patients-with-obesity-hypoventilation-syndrome-systematic-review-and-meta-analysis
#12
Caroline Persch Royer, Cláudia Schweiger, Denise Manica, Luisi Rabaioli, Vinicius Guerra, Graciele Sbruzzi
OBJECTIVE: To systematically review the effects of bilevel ventilatory support (BVS) in patients with Obesity Hypoventilation Syndrome (OHS). METHODS: A search of databases (MEDLINE accessed by PubMed, Cochrane CENTRAL, EMBASE and LILACS) was conducted from inception to June 2018. Randomized trials comparing BVS to other therapeutic modalities such as lifestyle counseling, continuous positive airway pressure (PAP) or BVS with average volume assured pressure support for the treatment of patients with OHS were included...
October 10, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/30528840/non-invasive-positive-pressure-ventilation-in-pneumonia-outside-intensive-care-unit-an-italian-multicenter-observational-study
#13
Anna Maria Brambilla, Elena Prina, Giovanni Ferrari, Viviana Bozzano, Rodolfo Ferrari, Paolo Groff, Giuseppina Petrelli, Raffaele Scala, Fabio Causin, Paola Noto, Emanuela Bresciani, Antonio Voza, Stefano Aliberti, Roberto Cosentini
BACKGROUND AND OBJECTIVE: Non-Invasive Ventilation (NIV) represents a standard of care to treat some acute respiratory failure (ARF). Data on its use in pneumonia are lacking, especially in a setting outside the Intensive Care Unit (ICU). The aims of this study were to evaluate the use of NIV in ARF due to pneumonia outside the ICU, and to identify risk factors for in-hospital mortality. METHODS: Prospective, observational study performed in 19 centers in Italy...
October 24, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/30524729/from-cpap-to-tailored-therapy-for-obstructive-sleep-apnoea
#14
REVIEW
Kate Sutherland, Kristina Kairaitis, Brendon J Yee, Peter A Cistulli
Obstructive Sleep Apnoea (OSA) is a common sleep disorder that is associated with daytime symptoms and a range of comorbidity and mortality. Continuous Positive Airway Pressure (CPAP) therapy is highly efficacious at preventing OSA when in use and has long been the standard treatment for newly diagnosed patients. However, CPAP therapy has well recognised limitations in real world effectiveness due to issues with patient acceptance and suboptimal usage. There is a clear need to enhance OSA treatment strategies and options...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/30523558/psychometric-properties-of-the-ethos-brief-index-ebi-using-factorial-structure-and-rasch-analysis-among-patients-with-obstructive-sleep-apnea-before-and-after-cpap-treatment-is-initiated
#15
Anders Broström, A H Pakpour, P Nilsen, B Fridlund, M Ulander
BACKGROUND: Continuous positive airway treatment (CPAP) is the recommended treatment for patients with obstructive sleep apnea (OSA). Outcome measures often focus on clinical and/or self-rated variables related to the medical condition. However, a brief validated instrument focusing on the whole life situation (i.e., ethos) suitable for clinical practice is missing. The aim of this study was to investigate factorial structure, categorical functioning of the response scale, and differential item functioning across sub-populations of the Ethos Brief Index (EBI) among patients with obstructive sleep apnea (OSA) before and after initiation of continuous positive airway pressure (CPAP)...
December 6, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/30523556/a-false-alarm-of-narcolepsy-obstructive-sleep-apnea-masquerading-as-narcolepsy-and-depression
#16
Dhirendra Paudel, Qiuyan Lin, Caiping Yan, Shuai Liu, Bin Zhang
PURPOSE: We report a case with symptoms and signs of obstructive sleep apnea (OSA), depression, and narcolepsy. Polysomnographic (PSG) and multiple sleep latency test (MSLT) findings, clinical characteristics, and diagnostic challenges in this case are discussed. METHODS: A 23-year-old single male presented with excessive daytime sleepiness, low mood, lack of energy, and snoring for 3 years. In addition, he reported excessive weight gain, lack of interest in work, partial loss of muscle tone during excitations, and sleep attacks during work and driving...
December 6, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/30522886/the-impact-of-continuous-positive-airway-pressure-treatment-on-the-recurrence-of-atrial-fibrillation-post-cardioversion-a-randomized-controlled-trial
#17
Sean M Caples, Meghna P Mansukhani, Paul A Friedman, Virend K Somers
BACKGROUND: Observational data suggest that positive airway pressure (PAP) treatment of obstructive sleep apnea (OSA) can reduce the risk of recurrent atrial fibrillation (AF) post-direct current cardioversion (DCCV) or catheter ablation. METHODS: We conducted a study of adult patients with AF and sleep apnea, stratified by age and gender, who underwent successful DCCV to sinus rhythm, and who were randomized to receive PAP or usual care. Those with sleepiness, significant cardiac or respiratory disease were excluded...
November 20, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/30522873/predictors-of-cpap-adherence-following-stroke-and-transient-ischemic-attack
#18
David R Colelli, Maneesha Kamra, Phavalan Rajendram, Brian J Murray, Mark I Boulos
OBJECTIVE: Continuous positive airway pressure (CPAP) has been shown to improve functional, motor and cognitive outcomes in post-stroke obstructive sleep apnea (OSA). However, rates of CPAP adherence are often low and factors impacting CPAP adherence remain under-explored. Our objective was to determine predictors of CPAP adherence in patients who had a stroke or transient ischemic attack (TIA). METHODS: We screened 313 stroke/TIA patients for OSA using in-hospital polysomnography or the ApneaLink home sleep apnea test...
October 24, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/30517889/diabetes-sleep-treatment-trial-premise-design-and-methodology
#19
Eileen R Chasens, Charles W Atwood, Lora E Burke, Mary Korytkowski, Robert Stansbury, Patrick J Strollo, Susan M Sereika
The Diabetes Sleep Treatment Trial (DSTT) is a multi-site, double-blinded, randomized, sham-controlled trial. The study objective is to test whether treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) treatment results in improved glycemic control and diabetes self-management behavior compared to participants on a sham-CPAP (sub-therapeutic) device in participants with type 2 diabetes mellitus (T2DM) and co-morbid OSA. The purpose of this paper is to describe the premise for the DSTT, the study design, and the methodology used in this on-going trial...
December 2, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/30517264/lobectomy-with-ecmo-support-in-an-infant-who-developed-pulmonary-interstitial-emphysema-following-repair-of-hypoplastic-aortic-arch
#20
Michael Magarakis, Dao M Nguyen, Alejandro E Macias, Eliot R Rosenkranz
Pulmonary interstitial emphysema (PIE) is a common problem in premature neonates with respiratory distress syndrome. This condition is often related to barotrauma caused by mechanical ventilation or continuous positive airway pressure applied to low birth weight neonates. The clinical diagnosis can be challenging. However, after proper diagnosis, several interventions are available for successful management. We describe an infant who developed severe PIE with recurrent pneumothoraces and development of a persistent bronchopleural fistula shortly after repair of a hypoplastic aortic arch and description of successful lobectomy with the assistance of extracorporeal support (ECMO)...
September 2018: Brazilian Journal of Cardiovascular Surgery
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