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Nutrition and Gestational Diabetes

Aleksandra Kozlowska, Anna Maja Jagielska, Katarzyna Malgorzata Okreglicka, Filip Dabrowski, Krzysztof Kanecki, Aneta Nitsch-Osuch, Miroslaw Wielgos, Dorota Bomba-Opon
OBJECTIVES: Maintaining proper nutrition during pregnancy is crucial for pregnant women and especially for who have been diagnosed with type 1 diabetes mellitus (T1DM) or who develop gestational diabetes mellitus (GDM). MATERIAL AND METHODS: To measure differences in vitamin and mineral intakes among women with normal pregnancies, pregnant women with GDM, and pregnant women with pre-gestational T1DM; and to assess the women's dietary intakes in comparison with Polish nutritional guidelines...
2018: Ginekologia Polska
Rosette J Chakkalakal, Amber J Hackstadt, Ricardo Trochez, Rebecca Gregory, Tom A Elasy
BACKGROUND: Women diagnosed with gestational diabetes mellitus (GDM) substantially modify their diets during pregnancy to control hyperglycemia. These changes could also affect maternal weight management. MATERIALS AND METHODS: From July 2014 to December 2015 we enrolled women with and without GDM in a prospective cohort study to compare their mean rates of (1) weight gain before GDM screening, (2) weight gain after GDM screening, and (3) postpartum weight loss...
November 17, 2018: Journal of Women's Health
Carla Assaf-Balut, Nuria Garcia de la Torre, Alejandra Durán, Manuel Fuentes, Elena Bordiú, Laura Del Valle, Johanna Valerio, Cristina Familiar, Inés Jiménez, Miguel Angel Herraiz, Nuria Izquierdo, Maria José Torrejón, Isabelle Runkle, Maria Paz de Miguel, Inmaculada Moraga, Maria Carmen Montañez, Ana Barabash, Martín Cuesta, Miguel A Rubio, Alfonso Luis Calle-Pascual
Objectives: To assess whether Mediterranean Diet (MedDiet)-based medical nutrition therapy facilitates near-normoglycemia in women with gestational diabetes mellitus (GDMw) and observe the effects on adverse pregnancy outcomes. Research design and methods: This is a secondary analysis of the St Carlos GDM Prevention Study, conducted between January and December 2015 in Hospital Clínico San Carlos (Madrid, Spain). One thousand consecutive women with normoglycemia were included before 12 gestational weeks (GWs), with 874 included in the final analysis...
2018: BMJ Open Diabetes Research & Care
Xinting Yu, Shi Song Rong, Xiujing Sun, Guofang Ding, Weilin Wan, Liying Zou, Shaowen Wu, Ming Li, Danhua Wang
Breast milk (BM) hormones have been hypothesised as a nutritional link between maternal and infant metabolic health. This study aimed to evaluate hormone concentrations in BM of women with and without gestational diabetes mellitus (GDM), and the relationship between maternal factors, BM hormones and infant growth. We studied ninety-six nulliparous women with (n 48) and without GDM and their exclusively breastfed term singletons. Women with GDM received dietary therapy or insulin injection for euglycaemia during pregnancy...
December 2018: British Journal of Nutrition
Fei Gao, Huabin Luo, Katherine Jones, Wanda Nicholson, Ronny A Bell
INTRODUCTION: Women with gestational diabetes are at 7 times greater risk of developing type 2 diabetes than are women without gestational diabetes. The objectives of this study were to examine recent changes in the prevalence of gestational diabetes mellitus among women of reproductive age in the United States and assess the prevalence of factors associated with participating in healthy lifestyle behaviors. METHODS: Data were from 4 waves of the National Health and Nutrition Examination Survey (2007-2014)...
October 25, 2018: Preventing Chronic Disease
Katrien Benhalima, Caro Minschart, Dries Ceulemans, Annick Bogaerts, Bart Van Der Schueren, Chantal Mathieu, Roland Devlieger
Gestational diabetes mellitus (GDM) is a frequent medical complication during pregnancy. This is partly due to the increasing prevalence of obesity in women of childbearing age. Since bariatric surgery is currently the most successful way to achieve maintained weight loss, increasing numbers of obese women of childbearing age receive bariatric surgery. Bariatric surgery performed before pregnancy significantly reduces the risk to develop GDM but the risk is generally still higher compared to normal weight pregnant women...
October 11, 2018: Nutrients
Taofeek O Usman, Emmanuel D Areola, Olufunto O Badmus, InKyeom Kim, Lawrence A Olatunji
Nutritional challenges and androgen excess have been implicated in the development of gestational diabetes and poor fetal outcome, but the mechanisms are not well delineated. The effects of short chain fatty acid (SCFA) on glucose dysmetabolism and poor fetal outcome induced by gestational androgen excess is also not known. We tested the hypothesis that blockade of androgen receptor (AR) and suppression of late gestational androgen excess prevents glucose dysmetabolism and poor fetal outcome through suppression of adenosine deaminase (ADA)/xanthine oxidase (XO) pathway...
September 5, 2018: Journal of Nutritional Biochemistry
Chiamaka Esther Amaefule, Zoe Drymoussi, Julie Dodds, Lorna Sweeney, Elena Pizzo, Jahnavi Daru, John Robson, Lucilla Poston, Asma Khalil, Jenny Myers, Angela Harden, Graham A Hitman, Khalid Khan, Javier Zamora, Mohammed S B Huda, Shakila Thangaratinam
INTRODUCTION: Gestational diabetes increases maternal and offspring complications in pregnancy and cardiovascular complications in the long term. The nutritional supplement myo -inositol may prevent gestational diabetes; however, further evaluation is required, especially in multiethnic high-risk mothers. Our pilot trial on myo -inositol to prevent gestational diabetes will evaluate trial processes, assess acceptability to mothers and obtain preliminary estimates of effect and cost data prior to a large full-scale trial...
September 24, 2018: BMJ Open
Alexandra K Adams, Emily J Tomayko, Kate A Cronin, Ronald J Prince, Kyungmann Kim, Lakeesha Carmichael, Tassy Parker
OBJECTIVE: To describe sociodemographic factors and health behaviors among American Indian (AI) families with young children and determine predictors of adult and child weight status among these factors. DESIGN: Descriptive, cross-sectional baseline data. SETTING: One urban area and 4 rural AI reservations nationwide. PARTICIPANTS: A total of 450 AI families with children aged 2-5years participating in the Healthy Children, Strong Families 2 intervention...
September 18, 2018: Journal of Nutrition Education and Behavior
Liyuan Zhou, Xinhua Xiao, Qian Zhang, Jia Zheng, Ming Li, Miao Yu, Xiaojing Wang, Mingqun Deng, Xiao Zhai, Rongrong Li
Maternal over-nutrition can lead to metabolic disorders in offspring, whereas maternal dietary genistein may have beneficial effects on the metabolic health of offspring. Our objective was to determine whether maternal dietary genistein could attenuate the detrimental effects of a maternal high-fat diet on their offspring's metabolism and to explore the role of the gut microbiota on their offspring's glucose and lipid metabolism. C57BL/6 female mice were fed either a high-fat diet without genistein (HF), high-fat diet with low-dose genistein (0...
2018: Frontiers in Endocrinology
Mini Joseph, Riddhi Das Gupta, Sahana Shetty, Roshna Ramachandran, Geethu Antony, Jiji Mathews, Santhosh Benjamin, Shajith Anoop, Jansi Vimala Rani, Nihal Thomas
Background: Diabetes is the most common condition in pregnancy with a worldwide prevalence of 16.9%. Aim: To determine the adequacy of the nutrient intake of pregnant women with diabetes mellitus. Methods: This is a cross-sectional study of 85 pregnant women who met the diagnostic inclusion criteria for diabetes mellitus (gestational and pre-gestational diabetes mellitus) and who were being managed at the outpatient clinic of a tertiary care teaching hospital...
October 2018: Journal of Obstetrics and Gynaecology of India
Camille Dugas, Julie Perron, Isabelle Marc, S John Weisnagel, Julie Robitaille
BACKGROUND: Children exposed to gestational diabetes mellitus (GDM) in utero are at high-risk of obesity. Given that nutritional habits can track from infancy to childhood, the aim of this study was to evaluate the association between the timing of fruit juice introduction in infancy and later consumption of sweet-tasting foods and beverages among children exposed (GDM+) and unexposed (GDM-) to GDM. METHODS: A total of 107 GDM+ and 59 GDM- participated in the project...
August 29, 2018: Appetite
Carla Gianfrancesco, Zoe Darwin, Linda McGowan, Debbie M Smith, Roz Haddrill, Michelle Carter, Eleanor M Scott, Nisreen A Alwan, Michelle A Morris, Salwa A Albar, Janet E Cade
myfood24 is an online 24 hr dietary recall tool developed for nutritional epidemiological research. Its clinical application has been unexplored. This mixed methods study explores the feasibility and usability of myfood24 as a food record in a clinical population, women with gestational diabetes (GDM). Women were asked to complete five myfood24 food records, followed by a user questionnaire (including the System Usability Scale (SUS), a measure of usability), and were invited to participate in a semi-structured interview...
August 23, 2018: Nutrients
Angelo Maria Patti, Rosaria Vincenza Giglio, Kalliopi Pafili, Manfredi Rizzo, Nikolaos Papanas
Gestational diabetes mellitus (GDM) represents impaired carbohydrate metabolism during pregnancy and is characterized by progressive insulin resistance and compensatory hyperinsulinaemia. If inadequately treated, it may lead to fetal macrosomia and other adverse outcomes. Areas covered: In this review, the authors summarize the current evidence from studies on the use of insulin and other agents for the treatment of women with GDM. Expert opinion: Lifestyle management is of paramount importance for the treatment of GDM...
September 2018: Expert Opinion on Pharmacotherapy
Ilario Ferrocino, Valentina Ponzo, Roberto Gambino, Adriana Zarovska, Filomena Leone, Clara Monzeglio, Ilaria Goitre, Rosalba Rosato, Angelo Romano, Giorgio Grassi, Fabio Broglio, Maurizio Cassader, Luca Cocolin, Simona Bo
Gestational diabetes mellitus (GDM), a common pregnancy complication, is associated with an increased risk of maternal/perinatal outcomes. We performed a prospective observational explorative study in 41 GDM patients to evaluate their microbiota changes during pregnancy and the associations between the gut microbiota and variations in nutrient intakes, anthropometric and laboratory variables. GDM patients routinely received nutritional recommendations according to guidelines. The fecal microbiota (by 16S amplicon-based sequencing), was assessed at enrolment (24-28 weeks) and at 38 weeks of gestational age...
August 15, 2018: Scientific Reports
María Limones, Julio Sevillano, María G Sánchez-Alonso, Emilio Herrera, María Del Pilar Ramos-Álvarez
BACKGROUND: Although recent studies have investigated the effect of maternal nutrition on metabolic programming of the offspring, the question whether a nutritional insult during early gestation favours an altered metabolic state of the mother that persists during the remainder period of pregnancy, when foetal growth is maximal, remains to be answered. METHODS: To address this issue, we analysed the effect of 40% food restriction during the first 12 days of gestation on glucose tolerance, as well as on liver and adipose tissue metabolism, in Sprague-Dawley pregnant rats...
August 14, 2018: European Journal of Nutrition
Ana Carolina Momentti, Débora Estadella, Luciana Pellegrini Pisani
There is a growing concern about the impacts of hypovitaminosis D on the health of pregnant woman, fetal development, childhood, and adult life. Variations in maternal nutrition during gestation and/or lactation play a critical role in the physiological and metabolic development of the fetus and neonate, which can induce phenotypic changes and trigger important consequences throughout life, such as type 2 diabetes, cardiovascular disease, obesity, and hypertension. Vitamin D plays a role in regulating cell proliferation and differentiation and in modulating the innate and adaptive immune response...
September 2018: Steroids
Elizabeth A Symington, Jeannine Baumgartner, Linda Malan, Lizelle Zandberg, Cristian Ricci, Cornelius M Smuts
BACKGROUND: Adequate nutrition during pregnancy is important to ensure optimal birth outcomes, maternal health and offspring development. However, little is known about the dietary intake and nutritional status of pregnant women residing in urban South Africa. Therefore, the Nutrition during Pregnancy and Early Development (NuPED) cohort study was initiated to assess early nutrition-related exposures predictive of early childhood development in urban South Africa. METHODS: The aims of this prospective cohort study are: 1) to assess dietary intake and nutritional status of urban pregnant women in Johannesburg, South Africa, and 2) to determine associations with birth outcomes, measures of maternal health, as well as measures of offspring health and development...
July 24, 2018: BMC Pregnancy and Childbirth
Yun-Su Kim, Hee-Seung Kim, Yoo-Lee Kim
BACKGROUND: Women diagnosed with gestational diabetes mellitus suffer from anxiety and depression, which make controlling blood glucose levels difficult. INTRODUCTION: This quasi-experimental study uses a nonequivalent control group pretest-posttest design to investigate the effects of a web-based self-care program on self-care behaviors, anxiety, depression, and blood glucose in patients with gestational diabetes mellitus. METHODS: The subjects of the study were outpatients being treated in the Department of Endocrinology at Hospital G, located in Seoul near University C, from July 15, 2015, to December 31, 2016...
July 23, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
Pedro C Marques, Gustavo Rocha, Filipa Flor-De-Lima, Hercília Guimarães
BACKGROUND: Extrauterine growth restriction (EUGR) remains a serious problem among very low birth weight (VLBW) infants and is a marker of severe nutritional deficit during the first weeks of life. It can lead to a higher risk of growth impairment during childhood and long-term medical problems. The aim of this study is to determine the prevalence and risk factors of EUGR in preterm infants below 1500 grams. METHODS: Descriptive retrospective study of all preterm infants with birth weight below 1500 grams who were born at and discharged from our center, from January 1, 2012 to December 31, 2016...
July 23, 2018: Minerva Pediatrica
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