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https://www.readbyqxmd.com/read/30336744/assessment-of-three-methods-for-removing-massive-air-in-a-cardiopulmonary-bypass-circuit-simulation-based-multi-discipline-training-in-west-china-hospital
#1
Ting Liu, Zhen Qin, Ming Luo, Zhao-Xia Tan, Ji-Yue Xiong, Gang-Jian Gu, Xiang Yu, Qi Li, Rong-Hua Zhou
BACKGROUND AND OBJECTIVE: A multi-discipline cardiac and cardiopulmonary bypass (CPB) team simulation scenario was established to compare three different de-airing approaches dealing with massive air embolism in CPB, so as to formulate a standardized procedure to handle this adverse acute event more proficiently and ensure clinical safety. METHOD: A simulation-based clinical CPB massive air embolism scenario was developed by a cardiac and CPB team. Study Objects: Five licensed perfusionists and five CPB trainees were matched randomly into five pairs...
October 19, 2018: Perfusion
https://www.readbyqxmd.com/read/30336384/totally-endoscopic-atrial-septal-defect-repair-using-transthoracic-aortic-cannulation-in-a-10-5-kg-boy
#2
Huy Q Dang, Huong T Le, Linh T H Ngo
INTRODUCTION: Although totally endoscopic surgery (TES) has been widely applied for the treatment of atrial septal defect (ASD), small children receive few benefits from this technique due to risks of the femoral cannulation. CASE PRESENTATION: A 23-month-old boy, weighing 10.5 kg, with the diagnosis of sinus venosus ASD underwent successful repair by TES. We performed this surgery through 4 small trocars (one 12 mm trocar and three 5 mm trocars), without robotic assistance...
October 10, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/30326552/pulse-oximetry-with-two-infrared-wavelengths-without-calibration-in-extracted-arterial-blood
#3
Ohad Yossef Hay, Meir Cohen, Itamar Nitzan, Yair Kasirer, Sarit Shahroor-Karni, Yitzhak Yitzhaky, Shlomo Engelberg, Meir Nitzan
Oxygen saturation in arterial blood (SaO₂) provides information about the performance of the respiratory system. Non-invasive measurement of SaO₂ by commercial pulse oximeters (SpO₂) make use of photoplethysmographic pulses in the red and infrared regions and utilizes the different spectra of light absorption by oxygenated and de-oxygenated hemoglobin. Because light scattering and optical path-lengths differ between the two wavelengths, commercial pulse oximeters require empirical calibration which is based on SaO₂ measurement in extracted arterial blood...
October 15, 2018: Sensors
https://www.readbyqxmd.com/read/30307851/multi-wavelength-photoplethysmography-enabling-continuous-blood-pressure-measurement-with-compact-wearable-electronics
#4
Jing Liu, Bryan Yan, Yuanting Zhang, Xiao-Rong Ding, Su Peng, Ni Zhao
OBJECTIVE: To fight the "silent killer" hypertension, continuous blood pressure (BP) monitoring has been one of the most desired functions in wearable electronics. However, current BP measuring principles and protocols either involve a vessel occlusion process with a cuff or require multiple sensing nodes on the body, which makes it difficult to implement them in compact wearable electronics like smartwatches and wristbands with long-term wearability. METHODS: In this work, we proposed a highly-compact multi-wavelength photoplethysmography (MWPPG) module and a depth-resolved MWPPG approach for continuous monitoring of BP and systemic vascular resistance (SVR)...
October 9, 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/30295583/upper-extremity-compartment-syndrome-following-radial-artery-puncture-in-a-patient-undergoing-orthotopic-liver-transplant
#5
Michelle Lipton, Stephen Aniskevich
Acute compartment syndrome is the physiologic consequence of increasing pressures within an enclosed anatomic space; if left untreated, it can subsequently cause irreversible necrosis, nerve injury, and tissue damage. A number of iatrogenic causes have been reported in the literature; however, to the best of our knowledge, there are no prior reports of upper extremity compartment syndrome in orthotopic liver transplant following arterial line placement. Here, we report a 52-year-old male with a history of end-stage liver disease secondary to primary sclerosing cholangitis who presented for orthotopic liver transplant...
October 5, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/30272526/lymphatic-vessels-a-potential-approach-to-the-treatment-of-atherosclerosis
#6
Zhi Zheng, Kun Ren, Xiaoshan Peng, Xiao Zhu, Guanghui Yi
Many basic and clinical studies have demonstrated that atherosclerosis is a chronic inflammatory disease. Although there are many factors affecting atherosclerosis, the role of lymphatic vessels in this disease has been neglected. Traditionally, lymphatic vessels have been considered to be passages for transporting interstitial fluid to the blood circulation. However, as early as the last century, researchers found that there are numerous lymphatic vessels surrounding sites of atherosclerosis; however, the relationship between lymphatic vessels and atherosclerosis is not clear...
September 29, 2018: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/30269682/weight-change-among-normal-weight-overweight-and-obese-employees-and-subsequent-diagnosis-specific-sickness-absence-a-register-linked-follow-up-study
#7
Anna Svärd, Jouni Lahti, Minna Mänty, Eira Roos, Ossi Rahkonen, Eero Lahelma, Tea Lallukka
AIMS: Obesity and weight change are associated with sickness absence; however, less is known about the diagnoses for sickness absence. We examined the association between stable and changing weight by body mass index groups with sickness absence due to any, musculoskeletal and mental diagnoses among midlife female and male employees. METHODS: The Finnish Helsinki Health Study phase 1 survey took place in 2000-2002 (response rate 67%) and phase 2 in 2007 (response rate 83%)...
September 29, 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/30215587/variation-in-the-management-of-isolated-craniosynostosis-a-survey-of-the-synostosis-research-group
#8
John R W Kestle, Amy Lee, Richard C E Anderson, Barbu Gociman, Kamlesh B Patel, Matthew D Smyth, Craig Birgfeld, Ian F Pollack, Jesse A Goldstein, Mandeep Tamber, Thomas Imahiyerobo, Faizi A Siddiqi
OBJECTIVE The authors created a collaborative network, the Synostosis Research Group (SynRG), to facilitate multicenter clinical research on craniosynostosis. To identify common and differing practice patterns within the network, they assessed the SynRG surgeons' management preferences for sagittal synostosis. These results will be incorporated into planning cooperative studies. METHODS The SynRG consists of 12 surgeons at 5 clinical sites. An email survey was distributed to SynRG surgeons in late 2016, and responses were collected through early 2017...
September 14, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/30214888/the-relationship-between-arterial-and-central-venous-blood-gases-values-in-patients-undergoing-mechanical-ventilation-after-cardiac-surgery
#9
Mohammadamin Valizad Hassanloei, Alireza Mahoori, Nazli Karami, Venus Sina
Background: The most straightforward method of ascertaining arterial PO2 , PCO2 , and other components of blood gas is to measure them directly from a blood sample. In situations in which arterial puncture cannot be achieved or may be technically difficult, the venous blood sample can be used. Methods: In a prospective analytical study, 80 patients undergoing mechanical ventilation after open-heart surgery in the intensive care unit were evaluated. Simultaneous, matched arterial and central venous blood gas samples were taken from radial artery line and central vein, respectively, when the ABG (arterial blood gases) assessment was needed...
June 2018: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/30189865/iatrogenic-cerebral-arterial-gas-embolism-from-flushing-of-the-arterial-line-in-two-calves
#10
Daniela Casoni, Alessandro Mirra, Christine Goepfert, Ilaria Petruccione, Claudia Spadavecchia
BACKGROUND: Measurement of invasive blood pressure as reflection of blood flow and tissue perfusion is often carried out in animals during general anesthesia. Intravascular cannulation offers the potential for gas to directly enter the circulation and lead to arterial gas embolism. Cerebral arterial gas embolism may cause a spectrum of adverse effects ranging from very mild symptoms to severe neurological injury and death. Although several experimental models of arterial gas embolism have been published, there are no known published reports of accidental iatrogenic cerebral arterial gas embolism from flushing of an arterial line in animals...
September 6, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/30176985/cost-of-vascular-access-devices-in-public-hospitals-in-queensland
#11
Haitham W Tuffaha, Nicole Marsh, Joshua Byrnes, Nicole Gavin, Joan Webster, Marie Cooke, Claire M Rickard
Objective The aim of this study was to quantify the utilisation of vascular access devices in Queensland public hospitals and their associated cost. Methods Devices were broadly classified into peripheral intravenous catheters, central venous catheters and arterial lines. The number of catheters used was obtained from a central procurement department at Queensland Health and validated using Medicare Benefits Schedule (MBS) claims and/or hospital data from the Australian Institute of Health and Welfare for the same period...
September 4, 2018: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/30142163/characterization-of-a-serologically-atypical-shigella-flexneri-z-isolated-from-diarrheal-patients-in-bangladesh-and-a-proposed-serological-scheme-for-shigella-flexneri
#12
Mohammad Shahnaij, Hasan A Latif, Ishrat J Azmi, Mohammed Badrul Amin, Sharmin J Luna, Mohammad Aminul Islam, Kaisar Ali Talukder
BACKGROUND: Atypical Shigella flexneri Z variant, that agglutinate with E1037 group factor specific monoclonal antisera against Shigella flexneri IV-I but not with other group or type specific antisera, has continuously being isolated in Bangladesh since 1997. Later this serotype has been reported in Indonesia, China and Argentina. Despite being a provisional serotype, continuous isolation of these strains in diverse geographical regions implicated a great necessity to study the overall characteristics of these strains...
2018: PloS One
https://www.readbyqxmd.com/read/30128592/pain-distress-the-negative-emotion-associated-with-procedures-in-icu-patients
#13
Kathleen A Puntillo, Adeline Max, Jean-Francois Timsit, Stephane Ruckly, Gerald Chanques, Gemma Robleda, Ferran Roche-Campo, Jordi Mancebo, Jigeeshu V Divatia, Marcio Soares, Daniela C Ionescu, Ioana M Grintescu, Salvatore Maurizio Maggiore, Katerina Rusinova, Radoslaw Owczuk, Ingrid Egerod, Elizabeth D E Papathanassoglou, Maria Kyranou, Gavin M Joynt, Gaston Burghi, Ross C Freebairn, Kwok M Ho, Anne Kaarlola, Rik T Gerritsen, Jozef Kesecioglu, Miroslav M S Sulaj, Michelle Norrenberg, Dominique D Benoit, Myriam S G Seha, Akram Hennein, Fernando J Pereira, Julie S Benbenishty, Fekri Abroug, Andrew Aquilina, Julia R C Monte, Youzhong An, Elie Azoulay
PURPOSE: The intensity of procedural pain in intensive care unit (ICU) patients is well documented. However, little is known about procedural pain distress, the psychological response to pain. METHODS: Post hoc analysis of a multicenter, multinational study of procedural pain. Pain distress was measured before and during procedures (0-10 numeric rating scale). Factors that influenced procedural pain distress were identified by multivariable analyses using a hierarchical model with ICU and country as random effects...
September 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/30097125/total-sesquiterpene-lactones-isolated-from-inula-helenium-l-attenuates-2-4-dinitrochlorobenzene-induced-atopic-dermatitis-like-skin-lesions-in-mice
#14
Qun Wang, Shuang Gao, Guo-Zhen Wu, Niao Yang, Xian-Peng Zu, Wen-Cai Li, Ning Xie, Rong-Rong Zhang, Chen-Wei Li, Zhen-Lin Hu, Wei-Dong Zhang
BACKGROUND: Inula helenium L. is an herb whose anti-inflammatory properties are attributed to its active components, the sesquiterpene lactones (SLs). Our previous study demonstrated that the total sesquiterpene lactones isolated from Inula helenium L. (TSL-IHL), consisting mainly of alantolactone (AL) and isoalantolactone (IAL), may have potential in the prevention and treatment of rheumatoid arthritis (RA). However, the effect of TSL-IHL on atopic dermatitis (AD) has not been studied yet...
July 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/30045259/effects-of-n-acetyl-cysteine-and-melatonin-on-early-reperfusion-injury-in-patients-undergoing-coronary-artery-bypass-grafting-a-randomized-open-labeled-placebo-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Ebrahim Shafiei, Mehrzad Bahtoei, Pema Raj, Afshin Ostovar, Daryoush Iranpour, Samad Akbarzadeh, Hooshang Shahryari, Abdorasoul Anvaripour, Rahim Tahmasebi, Thomas Netticadan, Ali Movahed
OBJECTIVES: This study assessed the efficacy of oral consumption of N-acetyl cysteine (NAC) and melatonin (ML) in reducing early reperfusion injury and acute oxidative stress in patients undergoing coronary artery bypass grafting (CABG) with respect to the measurements of cardiac troponin I, lactate, malondealdehyde (MDA), and tumor necrosis factor-α (TNF-α) levels in the blood. METHODS: This study was a randomized, open-label, placebo-controlled trial. Eighty eight patients, aged between 39 to 76 years and eligible for CABG, were recruited and randomly assigned into 3 intervention groups through a simple randomization method and underwent CABG surgery...
July 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30032348/traumatic-cardiac-arrest-and-resuscitative-endovascular-balloon-occlusion-of-the-aorta-reboa-a-preliminary-analysis-utilizing-high-fidelity-invasive-blood-pressure-recording-and-videography
#16
Philip J Wasicek, Shiming Yang, William A Teeter, Peter Hu, Deborah M Stein, Thomas M Scalea, Megan L Brenner
PURPOSE: Aortic occlusion (AO) increases proximal perfusion and may improve rates of return of spontaneous circulation (ROSC). The objective of this study was to investigate the hemodynamic effects of cardiopulmonary resuscitation (CPR) and AO by REBOA on patients in traumatic cardiac arrest. METHODS: Patients admitted between February 2013 and May 2017 at a tertiary center who suffered traumatic arrest, had an arterial line placed during resuscitation, and received CPR and REBOA which were included...
July 21, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/30031357/a-novel-technique-to-establish-hemodynamic-monitoring-in-patients-supported-with-extracorporeal-life-support-systems-ecls-for-cardiopulmonary-resuscitation-ecpr
#17
Dirk Lunz, Alois Philipp, Christoph Birner
PURPOSE: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to support conventional unsuccessful resuscitation and it is mandatory to rapidly initiate invasive hemodynamic monitoring, as soon as ECPR therapy is commenced. Commonly, this is achieved by establishing an additional arterial line via the right radial artery for invasive blood pressure measurement, but this can be challenging and risky on the one hand and might lead to erroneous measurements on the other hand...
October 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/30031055/chest-compression-rates-and-pediatric-in-hospital-cardiac-arrest-survival-outcomes
#18
Robert M Sutton, Ron W Reeder, William Landis, Kathleen L Meert, Andrew R Yates, John T Berger, Christopher J Newth, Joseph A Carcillo, Patrick S McQuillen, Rick E Harrison, Frank W Moler, Murray M Pollack, Todd C Carpenter, Daniel A Notterman, Richard Holubkov, J Michael Dean, Vinay M Nadkarni, Robert A Berg
AIM: The primary aim of this study was to evaluate the association between chest compression rates and 1) arterial blood pressure and 2) survival outcomes during pediatric in-hospital cardiopulmonary resuscitation (CPR). METHODS: Prospective observational study of children ≥37 weeks gestation and <19 years old who received CPR in an intensive care unit (ICU) as part of the Pediatric Intensive Care Unit Quality of CPR Study (PICqCPR) of the Collaborative Pediatric Critical Care Research Network (CPCCRN)...
September 2018: Resuscitation
https://www.readbyqxmd.com/read/30013612/the-reliability-of-carotid-ultrasound-in-determining-the-return-of-pulsatile-flow-a-pilot-study
#19
Biljana Germanoska, Matthew Coady, Sheyin Ng, Gary Fermanis, Matthew Miller
Manual palpation of pulses is unreliable in detecting pulsatile flow in human participants, complicating the assessment of return of spontaneous circulation after cardiac arrest. Ultrasound may offer an alternative. This study's objective was to investigate whether return of pulsatile flow in humans can be reliably assessed by common carotid artery ultrasound. We conducted a single-blinded randomised study of common carotid artery ultrasound using 20 cardiopulmonary bypass patients to model the return of pulsatile flow...
May 2018: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/30013035/isoalantolactone-suppresses-lps-induced-inflammation-by-inhibiting-traf6-ubiquitination-and-alleviates-acute-lung-injury
#20
Yun-He Ding, Yun-Duan Song, Ya-Xian Wu, Hui-Qiong He, Tian-Hong Yu, Yu-Dong Hu, De-Peng Zhang, Hong-Chao Jiang, Kai-Kai Yu, Xiao-Zong Li, Lei Sun, Feng Qian
Isoalantolactone (IAL) is a sesquiterpene lactone extracted from roots of Inula helenium L and has shown anti-inflammatory effects. In this study we investigated the therapeutic effects of IAL on acute lung injury (ALI) and elucidated the mechanisms underlying its anti-inflammation potential in vitro and in vivo. Treatment with lipopolysaccharide (LPS, 100 ng/mL) drastically stimulated production of inflammatory mediators such as NO, TNF-α, IL-1β, and IL-6 in mouse bone marrow-derived macrophages (BMDMs), which was dose-dependently suppressed by pretreatment with IAL (2...
July 16, 2018: Acta Pharmacologica Sinica
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