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"Acute Coronary Syndrome" OR "ACS"

Anjalee Chiwhane, Pradeep
Introduction: Cardiac rhythm disturbances are common presentation in acute coronary syndromes and are cause of frequent serious complications in acute myocardial infarction (AMI). However due to availability of early reperfusion therapy and primary angioplasty, arrhythmias have cause a reduction in mortality. Arrhythmias are key events before, during or after the occurrence of acute MI. There are few clinical studies describing the types of arryhthmias, their correlation with the clinical profile of acute MI and effect on outcomes...
January 2018: Journal of the Association of Physicians of India
Jorge Berladi, Pablo M Lamelas
Information of P2Y12 inhibitors in acute coronary syndromes with vein graft angioplasty is limited. This new analysis from the UK database was not able to find significant differences between Clopidogrel, Prasugrel and Ticagrelor. Large trials would be needed to reliably confirm the best antiplatelet regimen in this setting.
October 1, 2018: Catheterization and Cardiovascular Interventions
Taraneh Rajaei, Hamid Farajifard, Seyed Abdolrahim Rezaee, Mahmoud Reza Azarpazhooh, Mahmoud Mahmoudi, Narges Valizadeh, Houshang Rafatpanah
One of the prominent features of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the excessive recruitment of leukocytes to the central nervous system (CNS), which leads to an inflammatory response-with chemokines and their receptors playing the main role in this recruitment. The aim of the study was to examine the relation of CXCR1 and CXCR2, both of which are involved in the trafficking of lymphocytes into the CNS, with the outcome of HTLV-1 infection. The mRNA levels of CXCR1 and CXCR2 were examined in peripheral blood mononuclear cells (PBMCs) of HAM/TSP patients, HTLV-1 asymptomatic carriers (ACs), and healthy controls (HCs)...
October 20, 2018: Medical Microbiology and Immunology
Serge Korjian, Eugene Braunwald, Yazan Daaboul, Michael Mi, Deepak L Bhatt, Freek W A Verheugt, Marc Cohen, Christoph Bode, Paul Burton, Alexei N Plotnikov, C Michael Gibson
Patients with both acute coronary syndromes (ACS) and congestive heart failure are at an increased risk of recurrent cardiovascular (CV) events attributed in part to both excess thrombin generation and impaired fibrinolysis. We hypothesized that patients with the overlap of ACS and CHF would thus derive particular benefit from antithrombotic therapy with rivaroxaban. ATLAS-ACS-2 Thrombolysis in Myocardial Infarction-51 was a double-blind, multicenter, phase 3 clinical trial that randomized patients within 7 days of an ACS event to standard of care plus either rivaroxaban 2...
September 7, 2018: American Journal of Cardiology
Fengyue Suo, Xue Liu, Changsheng Li, Meng Yuan, Bingjie Zhang, Jianli Wang, Yongqiang Ma, Zemin Lai, Mingshan Ji
Pesticides contamination of water has caused considerable concern due to the potential hazard to human health. For the first time, mesoporous activated carbon from starch (ACS) was applied to remove pesticides from water. ACS could remove 11 pesticides rapidly (shake five times). The adsorption rates of ACS (>80%) for the 11 pesticides were higher than those of other adsorbents, including commercial activated carbon (AC), graphitised carbon black (GCB), C18, and primary secondary amine adsorbent (PSA). The mechanisms of the adsorption process for pyraclostrobin were also investigated...
October 16, 2018: International Journal of Biological Macromolecules
Mark A Guinter, Marjorie L McCullough, Susan M Gapstur, Peter T Campbell
PURPOSE: Dietary patterns, indicators of overall diet quality, are associated with colorectal cancer (CRC) incidence but less consistently with mortality among CRC survivors. We prospectively evaluated associations of diet quality pre- and postdiagnosis with risk of mortality among men and women with CRC. PATIENTS AND METHODS: In the Cancer Prevention Study-II Nutrition Cohort, 2,801 participants were cancer free at baseline in 1992/1993 and subsequently diagnosed with invasive, nonmetastatic CRC during follow-up through June 2013...
October 19, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Anirban Bhandari, Ram Chandra Maji, Saikat Mishra, Akhilesh Kumar, Suman Kumar Barman, Partha Pratim Das, Kamran B Ghiassi, Marilyn M Olmstead, Apurba K Patra
Aliphatic thiolato-S-bridged tri- and binuclear nickel(II) complexes have been synthesized and characterized as models for the Nip site of the A cluster of acetyl coenzyme A synthase (ACS)/carbon monooxide (CO) dehydrogenase. Reaction of the in situ formed N2 Sthiol donor ligands with [Ni(H2 O)6 ](ClO4 )2 afforded the trinuclear complexes [Ni{(LMe(S) )2 Ni}2 ](ClO4 )2 ·CH3 CN (1·CH3 CN) and [Ni{(LBr(S) )2 Ni}2 ](ClO4 )2 ·5H2 O (2·5H2 O) following self-assembly. Complexes 1 and 2 react with [Ni(dppe)Cl2 ] and dppe [dppe = 1,2-bis(diphenylphosphino)ethane] to afford the binuclear [Ni(dppe)Ni(LMe(S) )2 ](ClO4 )2 ·2H2 O (3·2H2 O) and [Ni(dppe)Ni(LBr(S) )2 ](ClO4 )2 ·0...
October 19, 2018: Inorganic Chemistry
Serkan Ünlü, Asife Şahinarslan, Burak Sezenöz, Orhan Mecit Uludağ, Gökhan Gökalp, Özden Seçkin, Selim Turgay Arınsoy, Özlem Gülbahar, Nuri Bülent Boyacı
BACKGROUND: Circulating troponin levels are both stable and higher in patients with end-stage renal disease, even in the absence of acute coronary syndrome. These patients commonly have underlying cardiac problems that frequently cause troponin elevation. The effect of hemodialysis (HD) on troponin levels has not been well elucidated. Thus, investigated herein is the relationship between the changes in troponin levels along with left ventricular deformation and volume depletion in patients with end-stage renal disease...
October 19, 2018: Cardiology Journal
Javier Suárez de Lezo, Pedro Martín, Jorge Chavarría
No abstract text is available yet for this article.
2018: Kardiologia Polska
Gerd Hasenfuß
Prevention strategies for cardiac events depend of the risk for such an event. A very high risk is defined by a risk >10% over 10 years. For example, a patient with known coronary artery disease has such a very high risk to die. However a patient with diabetes and severe hypertension without known coronary artery disease carries the same risk. Here, secondary prevention and primary prevention overlap. Prevention guidelines include a number of general recommendations such as changes in behavior, smoking intervention strategies, nutrition, body weight, and physical activity...
October 19, 2018: Kardiologia Polska
Mana Doi, Hiroki Fukahori, Yumiko Oyama, Kumiko Morita
Aim: To identify the association between possible factors and depression among post-percutaneous coronary intervention patients with acute coronary syndrome. Design: Prospective cohort study. Methods: Sixty-eight post-percutaneous coronary intervention patients with acute coronary syndrome were enrolled between January 2016 - June 2017. The Hospital Anxiety and Depression Scale scores at 1-3 months after discharge were regressed onto uncertainty in illness and other clinical factors based on the Roy Adaptation Model...
October 2018: Nursing Open
Yutaka Igarashi, Shoji Yokobori, Hidetoshi Yamana, Kosuke Nagakura, Jun Hagiwara, Tomohiko Masuno, Hiroyuki Yokota
Aim: In Japan, standard prehospital care is provided by emergency medical services teams. Doctor-staffed ambulances play a role in facilitating the immediate treatment of critically ill patients to increase the survival rates. However, little is known about their activities. We revealed the present situation of doctor-staffed ambulances in Japan. Methods: First, we surveyed all the fire departments in Japan and determined whether a doctor-staffed ambulance was present within their district boundary...
October 2018: Acute Medicine & Surgery
Anne-Sophie Schuurman, Maxime M Vroegindewey, Isabella Kardys, Rohit M Oemrawsingh, Hector M Garcia-Garcia, Robert-Jan van Geuns, Evelyn Regar, Nicolas M Van Mieghem, Jurgen Ligthart, Patrick W Serruys, Eric Boersma, K Martijn Akkerhuis
BACKGROUND: It has been shown that intravascular ultrasound (IVUS) and radiofrequency (RF-)IVUS can detect high-risk coronary plaque characteristics. OBJECTIVES: The authors studied the long-term prognostic value of (RF-)IVUS-derived plaque characteristics in patients with coronary artery disease (CAD) undergoing coronary angiography. METHODS: From 2008 to 2011, (RF-)IVUS was performed in 1 nonstenotic segment of a nonculprit coronary artery in 581 patients undergoing coronary angiography for acute coronary syndrome (ACS) or stable angina...
October 23, 2018: Journal of the American College of Cardiology
Ehtisham Mahmud, Ori Ben-Yehuda
No abstract text is available yet for this article.
October 23, 2018: Journal of the American College of Cardiology
Krishnaraj S Rathod, Sudheer Koganti, Ajay K Jain, Zoe Astroulakis, Pitt Lim, Roby Rakhit, Sundeep Singh Kalra, Miles C Dalby, Constantinos O'Mahony, Iqbal S Malik, Charles J Knight, Anthony Mathur, Simon Redwood, Alexander Sirker, Philip A MacCarthy, Elliot J Smith, Andrew Wragg, Daniel A Jones
BACKGROUND: A large proportion of patients presenting with non-ST-segment elevation myocardial infarction (NSTEMI) present with multivessel disease (MVD). There is uncertainty in the role of complete coronary revascularization in this group of patients. OBJECTIVES: The aim of this study was to investigate the outcomes of complete revascularization compared with culprit vessel-only intervention in a large contemporary cohort of patients undergoing percutaneous coronary intervention (PCI) for NSTEMI...
October 23, 2018: Journal of the American College of Cardiology
Pontus Andell, Karolina Berntorp, Evald H Christiansen, Ingibjörg J Gudmundsdottir, Lennart Sandhall, Dimitrios Venetsanos, David Erlinge, Ole Fröbert, Sasha Koul, Christian Reitan, Matthias Götberg
OBJECTIVES: The authors sought to compare reclassification of treatment strategy following instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR). BACKGROUND: iFR was noninferior to FFR in 2 large randomized controlled trials in guiding coronary revascularization. Reclassification of treatment strategy by FFR is well-studied, but similar reports on iFR are lacking. METHODS: The iFR-SWEDEHEART (Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve in Patients With Stable Angina Pectoris or Acute Coronary Syndrome Trial) study randomized 2,037 participants with stable angina or acute coronary syndrome to treatment guided by iFR or FFR...
October 22, 2018: JACC. Cardiovascular Interventions
Eisuke Usui, Taishi Yonetsu, Yoshihisa Kanaji, Masahiro Hoshino, Masao Yamaguchi, Masahiro Hada, Tadashi Fukuda, Yohei Sumino, Hiroaki Ohya, Rikuta Hamaya, Yoshinori Kanno, Haruhito Yuki, Tadashi Murai, Tetsumin Lee, Kenzo Hirao, Tsunekazu Kakuta
OBJECTIVES: This study sought to investigate the relationship of unstable plaque features with physiological lesion severity and microvascular dysfunction. BACKGROUND: The functional severity of epicardial lesions and microvascular dysfunction are both related to adverse clinical outcomes. METHODS: We investigated 382 de novo intermediate and severe coronary lesions in 340 patients who underwent optical coherence tomography, fractional flow reserve (FFR), and index of microcirculatory resistance (IMR) examinations...
October 22, 2018: JACC. Cardiovascular Interventions
(no author information available yet)
No abstract text is available yet for this article.
October 17, 2018: Journal of the American Chemical Society
Jean Ferrieres, Gaetano Maria De Ferrari, Michel P Hermans, Moses Elisaf, Peter P Toth, Martin Horack, Philippe Brudi, Dominik Lautsch, Lori D Bash, Carl A Baxter, Veronica Ashton, Baishali Ambegaonkar, Anselm K Gitt
Background Patients with coronary heart disease (CHD) and survivors of acute coronary syndrome (ACS) are at very high risk for adverse cardiovascular events. Lowering low-density lipoprotein cholesterol (LDL-C) can reduce the risk, with effective lipid-lowering therapy (LLT) readily available; however, dyslipidemia remains prevalent throughout Europe. Design The observational Dyslipidemia International Study II (DYSIS II) aimed to identify unmet treatment needs in adult ACS and CHD patients. Data for the seven participating European countries are presented herein...
October 18, 2018: European Journal of Preventive Cardiology
Acs Contributing Correspondents
No abstract text is available yet for this article.
October 18, 2018: Journal of Physical Chemistry Letters
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