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JAMA rare case

Gargi Kapatia, Kirti Gupta, Oshan Shrestha, Anil Kumar, Ashish Bhalla
While adenoid cystic carcinoma is a common malignancy to arise within the salivary glands (21.9%) (Kokemueller et al. in Int J Oral Maxillofac Surg 33:25-31, 2004), it is seldom encountered as a tracheal mass and represents < 1% of all lung cancers. Tracheal tumors are an uncommon cause of dyspnoea due to their relatively rare occurrence (Baydur and Gottlieb in JAMA 234:829-831, 1975). They pose considerable diagnostic challenge clinically as their symptoms mimics more commoner ailments like asthma and chronic bronchitis...
April 23, 2018: Head and Neck Pathology
Simona Jarc, Miloš Miler, Stanka Šebela, Nina Zupančič
In the caves, the formation of cave minerals is a consequence of a variety of chemical reactions, some of them also due to human activity. There are many caves in Slovenia, but sulphate minerals are not very often reported and analysed. In this study, the presence of sulphate minerals is detected by SEM/EDS analysis of speleothems from Črna Jama, a cave near Kočevje (southern Slovenia). The cave is characterised by its dark, almost black colour on cave walls, floor and speleothems. Anthropogenic influence in the cave is still visible, including the remains of a fireplace, some inscriptions on the walls and wooden containers...
December 2017: Environmental Science and Pollution Research International
Néstor Gómez Cuesta, Jorge Ayón Ho, Jama Stanley, Alba María Caviedes Merchán
The intestinal pneumatosis is a clinical entity that is described as the presence of gas within the intestinal wall and portomesenteric venous complex as an air cysts without surrounded or no epithelial lining by a granulomatous infiltrate with giant cells multinucleic.1 It is a extremely rare clinical entity that has been characteristically associated with intestinal ischemia and high mortality. We present two cases of intestinal pneumatosis tomographic reports, admitted with clinical symptoms of intestinal obstruction...
September 2015: Acta Gastroenterologica Latinoamericana
Yuji Hirai, Sayaka Asahata-Tago, Yusuke Ainoda, Takahiro Fujita, Ken Kikuchi
BACKGROUND: Edwardsiella tarda bacteremia (ETB) can be a fatal disease in humans. OBJECTIVES: To determine the significant risk factors associated with death caused by ETB, and to examine the geographical, seasonal, environmental and dietary factors of the disease. METHODS: A retrospective, observational, case control study was performed. The PubMed MEDLINE and Japanese Medical Abstract Society ( databases were searched for ETB case reports and meeting abstracts...
November 2015: Canadian Journal of Infectious Diseases & Medical Microbiology
E George, Tan Jama, A S Nor Azian, A Rahimah, Z Zubaidah
A rare case of thalassaemia-intermedia involving a non-deletion alpha thalassemia point mutation in the alpha1-globin gene CD59 (GGC --> GAC) and a deletion alpha+ (-alpha(3.7)) thalassaemia in which use of high performance liquid chromatography (HPLC) C-gram Hb subtype profile and DNA molecular analysis helped establish the diagnosis.
December 2009: Medical Journal of Malaysia
A Mackinnon
BACKGROUND: Multiple imputation (MI) is an advanced, principled method of dealing with missing data in statistical analyses, a common problem in medical research. This paper sought to document the use of MI in general medical journals and to evaluate the information provided to readers about the application of the procedure in studies. METHODS: Research articles using MI in analyses published in JAMA, New England Journal of Medicine, BMJ and the Lancet were identified using full text searches from the earliest date each journal offered such searches until the end of 2008...
December 2010: Journal of Internal Medicine
M S Rahman, Turki Gasem, S A Al Suleiman, Fathia E Al Jama, Sameera Burshaid, Jessica Rahman
OBJECTIVES: The objective was to determine the prevalence of bladder injury during cesarean section (CS) and identify the risk factors causing these injuries, their management and the outcome. METHODS: We retrospectively reviewed the medical records of all the patients who had bladder injury during CS over a period of 25 years (1983-2007) at the King Fahad Hospital, Al-Khobar, Saudi Arabia. Demographic data, obstetric, surgical details, mechanism of injury, anatomic location, diagnosis, management and outcome were assessed...
March 2009: Archives of Gynecology and Obstetrics
G A Ankra-Badu, A Al-Jama, Y Al Kadim
BACKGROUND: The Al-Qatif region in the Eastern province of Saudi Arabia has the highest prevalence of a-thalassemia genes in the Kingdom. Hemoglobin H (Hb H) disease, however, has been rarely reported. We decided therefore to verify the rarity of the disease, and characterize the presenting features in cases identified. PATIENTS AND METHODS: All patients seen in Qatif Central Hospital between September 1988 and November 1990 with low red cell indices were screened for Hb H disease, and those found positive had clinical data compiled from their hospital records and analyzed...
September 2001: Annals of Saudi Medicine
Melinda Procter, Lan-Szu Chou, Wei Tang, Mohamed Jama, Rong Mao
BACKGROUND: Approximately 99% of Prader-Willi syndrome (PWS) and 80% of Angelman syndrome (AS) cases have deletions at a common region in chromosome 15q11.2-q13, uniparental disomy for chromosome 15 (UPD15), or imprinting center defects affecting gene expression in this region. The resulting clinical phenotype (PWS or AS) in each class of genomic abnormalities depends on the parent of origin. Both disorders are characterized at the molecular level by abnormal methylation of imprinted regions at 15q11...
July 2006: Clinical Chemistry
Mohammad Sayedur Rahman, Mohammad Hisham Al-Sibai, Jessica Rahman, Suleiman Awdah Al-Suleiman, Abdul Rahman El-Yahia, Abdul Aziz Al-Mulhim, Fathia Al-Jama
BACKGROUND: The purpose of this study was to review patients with ovarian cancer in pregnancy, the effectiveness of the available methods of treatment and their prognosis. METHODS: A retrospective review of all women diagnosed to have cancer of the ovary associated with pregnancy who delivered at the authors' hospitals between January 1976 and December 2000. The demography, clinical presentation, time and mode of diagnosis, treatment, pregnancy outcome and maternal survival were noted...
March 2002: Acta Obstetricia et Gynecologica Scandinavica
Ali Hassan Al Jama, Ahmed Hassan Al Salem, Ibrahim Abdalla Al Dabbous
Splenic infarcts are common in patients with sickle cell anemia (SCA), but these are usually small and repetitive, leading ultimately to autosplenectomy. Massive splenic infarcts on the other hand are extremely rare. This is a report of our experience with 8 (4 males and 4 females) cases of massive splenic infarction in patients with SCA. Their ages ranged from 16 to 36 years (mean 22 years). Three presented with left upper quadrant abdominal pain and massive splenic infarction on admission, while the other 5 developed massive splenic infarction while in hospital...
March 2002: American Journal of Hematology
K R Johnson, C R Braden, K L Cairns, K W Field, A C Colombel, Z Yang, C L Woodley, G P Morlock, A M Weber, A Y Boudreau, T A Bell, I M Onorato, S E Valway, P A Stehr-Green
CONTEXT: Washington State has a relatively low incidence rate of tuberculosis (TB) infection. However, from May to September 1997, 3 cases of pulmonary TB were reported among medical waste treatment workers at 1 facility in Washington. There is no previous documentation of Mycobacterium tuberculosis transmission as a result of processing medical waste. OBJECTIVE: To identify the source(s) of these 3 TB infections. DESIGN, SETTING, AND PARTICIPANTS: Interviews of the 3 infected patient-workers and their contacts, review of patient-worker medical records and the state TB registry, and collection of all multidrug-resistant TB (MDR-TB) isolates identified after January 1, 1995, from the facility's catchment area; DNA fingerprinting of all isolates; polymerase chain reaction and automated DNA sequencing to determine genetic mutations associated with drug resistance; and occupational safety and environmental evaluations of the facility...
October 4, 2000: JAMA: the Journal of the American Medical Association
R P Wise, M E Salive, M M Braun, G T Mootrey, J F Seward, L G Rider, P R Krause
CONTEXT: Since its licensure in 1995, the extensive use of varicella vaccine and close surveillance of the associated anecdotal reports of suspected adverse effects provide the opportunity to detect potential risks not observed before licensure because of the relatively small sample size and other limitations of clinical trials. OBJECTIVES: To detect potential hazards, including rare events, associated with varicella vaccine, and to assess case reports for clinical and epidemiological implications...
September 13, 2000: JAMA: the Journal of the American Medical Association
H A Guess
In case-control studies of adverse drug effects there is rarely much evidence to support the assumption that the hazard function among users is constant during therapy. Nonetheless, this assumption is often implicitly made. We will use both clinical reasoning and a simple model to show how non-constancy of the hazard function affects odds ratio interpretation. When the hazard function is non-constant and there is more than one temporal pattern of drug usage, the odds ratio will estimate a weighted mean of incidence ratios with weights dependent on the corresponding fractions of person-time...
1989: Journal of Clinical Epidemiology
J P Kleiner, W P Nelson
Since its original description in the English literature 15 years ago, high altitude pulmonary edema (HAPE) has been the subject of many reports. The clinical and hemodynamic features of HAPE are now well recognized, but its underlying pathophysiology remains unclear. In this article, a case of HAPE is described and the clinical features, proposed pathogenesis, and treatment are discussed. (JAMA 234:491-495, 1975).
November 3, 1975: JAMA: the Journal of the American Medical Association
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