Lifei Lu, Fan Wu, Jieqi Peng, Xiaohui Wu, Xiangqing Hou, Youlan Zheng, Huajing Yang, Zhishan Deng, Cuiqiong Dai, Ningning Zhao, Kunning Zhou, Qi Wan, Gaoying Tang, Jiangyu Cui, Shuqing Yu, Xiangwen Luo, Changli Yang, Shengtang Chen, Pixin Ran, Yumin Zhou
BACKGROUND: The clinical significance of the impulse oscillometry-defined small airway bronchodilator response (IOS-BDR) is not well-known. Accordingly, this study investigated the clinical characteristics of IOS-BDR and explored the association between lung function decline, acute respiratory exacerbations, and IOS-BDR. METHODS: Participants were recruited from an Early Chronic Obstructive Pulmonary Disease (ECOPD) cohort subset and were followed up for two years with visits at baseline, 12 months, and 24 months...
March 30, 2024: Respiratory Research