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https://www.readbyqxmd.com/read/28531962/how-geostatistics-can-help-you-find-lead-and-galvanized-water-service-lines-the-case-of-flint-mi
#1
Pierre Goovaerts
In the aftermath of Flint drinking water crisis, most US cities have been scrambling to locate all lead service lines (LSLs) in their water supply systems. This information, which is most often inaccurate or lacking, is critical to assess compliance with the Lead and Copper Rule and to plan the replacement of lead and galvanized service lines (GSLs) as currently under way in Flint. This paper presents the first geospatial approach to predict the likelihood that a home has a LSL or GSL based on neighboring field data (i...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28531890/update-in-intracerebral-hemorrhages-part-2-patients-at-risk-associated-with-vascular-lesions
#2
Michael G Hennerici
No abstract text is available yet for this article.
May 23, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28531806/standard-body-space-relationships-fingers-hold-spatial-information
#3
Daniele Romano, Francesco Marini, Angelo Maravita
The representation of the body in the brain is constantly updated to allow optimal sensorimotor interactions with the external world. In addition to dynamic features, body representation holds stable features that are still largely unknown. In the present work we explored the hypothesis that body parts have preferential associations with relative spatial locations. Specifically, in three experiments, we found consistent preferential associations between the index finger and the top position, and between the thumb and the bottom position...
May 19, 2017: Cognition
https://www.readbyqxmd.com/read/28531635/obesity-paradox-in-elderly-patients-with-cardiac-failure-an-updated-review-of-current-evidence
#4
Ioannis Doundoulakis, Kalliopi-Anna Poulia, Christina Antza, Eirini Kasapidou, Michael Chourdakis
No abstract text is available yet for this article.
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531376/immune-cell-signaling-in-autoimmune-diseases
#5
REVIEW
George C Tsokos, Noel R Rose
On September 20, 2016 the American Autoimmune Related Disease Association convened a selected group of 16 experts in Washington DC to discuss current issues and future directions of research in autoimmune diseases from the cell signaling perspective. The major topics considered included new findings on the follicular T cell cells in mice, their metabolic patterns and their control by the newly discovered T follicular regulatory cells. Current work on the metabolic pathways deemed important for the function of T cells was presented...
May 19, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/28531300/anosmia-a-clinical-review
#6
Sanne Boesveldt, Elbrich M Postma, Duncan Boak, Antje Welge-Luessen, Veronika Schöpf, Joel D Mainland, Jeffrey Martens, John Ngai, Valerie B Duffy
Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disorders impair the ability to sense warning odors in foods and the environment, as well as hinder the quality of life related to social interactions, eating, and feelings of well-being. This article reports and extends on a clinical update commencing at the 2016 Association for Chemoreception Sciences annual meeting...
May 22, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28531267/alignment-of-1000-genomes-project-reads-to-reference-assembly-grch38
#7
Xiangqun Zheng-Bradley, Ian Streeter, Susan Fairley, David Richardson, Laura Clarke, Paul Flicek
BACKGROUND: The 1000 Genomes Project produced more than 100 trillion basepairs of short read sequence from more than 2600 samples in 26 populations over a period of five years. In its final phase, the project released over 85 million genotyped and phased variants on human reference genome assembly GRCh37. An updated reference assembly, GRCh38, was released in late 2013, but there was insufficient time for the final phase of the project analysis to change to the new assembly. Although it is possible to lift the coordinates of the 1000 Genomes project variants to the new assembly, this is a potentially error prone process as coordinate remapping is most appropriate only for non-repetitive regions of the genome and those that did not see significant change between the two assemblies...
May 20, 2017: GigaScience
https://www.readbyqxmd.com/read/28531222/monitoring-the-elimination-of-human-african-trypanosomiasis-update-to-2014
#8
José R Franco, Giuliano Cecchi, Gerardo Priotto, Massimo Paone, Abdoulaye Diarra, Lise Grout, Raffaele C Mattioli, Daniel Argaw
BACKGROUND: The World Health Organization (WHO) has targeted the elimination of Human African trypanosomiasis (HAT) 'as a public health problem' by 2020. The selected indicators of elimination should be monitored every two years, and we provide here a comprehensive update to 2014. The monitoring system is underpinned by the Atlas of HAT. RESULTS: With 3,797 reported cases in 2014, the corresponding milestone (5,000 cases) was surpassed, and the 2020 global target of 'fewer than 2,000 reported cases per year' seems within reach...
May 22, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28531135/aekf-slam-a-new-algorithm-for-robotic-underwater-navigation
#9
Xin Yuan, José-Fernán Martínez-Ortega, José Antonio Sánchez Fernández, Martina Eckert
In this work, we focus on key topics related to underwater Simultaneous Localization and Mapping (SLAM) applications. Moreover, a detailed review of major studies in the literature and our proposed solutions for addressing the problem are presented. The main goal of this paper is the enhancement of the accuracy and robustness of the SLAM-based navigation problem for underwater robotics with low computational costs. Therefore, we present a new method called AEKF-SLAM that employs an Augmented Extended Kalman Filter (AEKF)-based SLAM algorithm...
May 21, 2017: Sensors
https://www.readbyqxmd.com/read/28531134/improving-video-segmentation-by-fusing-depth-cues-and-the-visual-background-extractor-vibe-algorithm
#10
Xiaoqin Zhou, Xiaofeng Liu, Aimin Jiang, Bin Yan, Chenguang Yang
Depth-sensing technology has led to broad applications of inexpensive depth cameras that can capture human motion and scenes in three-dimensional space. Background subtraction algorithms can be improved by fusing color and depth cues, thereby allowing many issues encountered in classical color segmentation to be solved. In this paper, we propose a new fusion method that combines depth and color information for foreground segmentation based on an advanced color-based algorithm. First, a background model and a depth model are developed...
May 21, 2017: Sensors
https://www.readbyqxmd.com/read/28530898/chronic-constipation-update-on-management
#11
REVIEW
Umar Hayat, Mohannad Dugum, Samita Garg
Managing chronic constipation involves identifying and treating secondary causes, instituting lifestyle changes, prescribing pharmacologic and nonpharmacologic therapies, and, occasionally, referring for surgery. Several new drugs have been approved, and others are in the pipeline.
May 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28530687/june-updates-people-places
#12
(no author information available yet)
No abstract text is available yet for this article.
May 22, 2017: Lab Animal
https://www.readbyqxmd.com/read/28530671/cardiopulmonary-assessment-of-patients-with-systemic-sclerosis-for-hematopoietic-stem-cell-transplantation-recommendations-from-the-european-society-for-blood-and-marrow-transplantation-autoimmune-diseases-working-party-and-collaborating-partners
#13
REVIEW
D Farge, R K Burt, M-C Oliveira, E Mousseaux, M Rovira, Z Marjanovic, J de Vries-Bouwstra, N Del Papa, R Saccardi, S J Shah, D C Lee, C Denton, T Alexander, D G Kiely, J A Snowden
Systemic sclerosis (SSc) is a rare disabling autoimmune disease with a similar mortality to many cancers. Two randomized controlled trials of autologous hematopoietic stem cell transplantation (AHSCT) for SSc have shown significant improvement in organ function, quality of life and long-term survival compared to standard therapy. However, transplant-related mortality (TRM) ranged from 3-10% in patients undergoing HSCT. In SSc, the main cause of non-transplant and TRM is cardiac related. We therefore updated the previously published guidelines for cardiac evaluation, which should be performed in dedicated centers with expertize in HSCT for SSc...
May 22, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28530551/angular-velocity-integration-in-a-fly-heading-circuit
#14
Daniel Turner-Evans, Stephanie Wegener, Hervé Rouault, Romain Franconville, Tanya Wolff, Johannes D Seelig, Shaul Druckmann, Vivek Jayaraman
Many animals maintain an internal representation of their heading as they move through their surroundings. Such a compass representation was recently discovered in a neural population in the Drosophila melanogaster central complex, a brain region implicated in spatial navigation. Here, we use two-photon calcium imaging and electrophysiology in head-fixed walking flies to identify a different neural population that conjunctively encodes heading and angular velocity, and is excited selectively by turns in either the clockwise or counterclockwise direction...
May 22, 2017: ELife
https://www.readbyqxmd.com/read/28530428/short-term-memory-and-long-term-memory-are-still-different
#15
Dennis Norris
A commonly expressed view is that short-term memory (STM) is nothing more than activated long-term memory. If true, this would overturn a central tenet of cognitive psychology-the idea that there are functionally and neurobiologically distinct short- and long-term stores. Here I present an updated case for a separation between short- and long-term stores, focusing on the computational demands placed on any STM system. STM must support memory for previously unencountered information, the storage of multiple tokens of the same type, and variable binding...
May 22, 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28530383/diabetes-update-prevention-and-management-of-diabetes-complications
#16
Beth Choby
Macrovascular complications of diabetes include cardiovascular events, whereas common microvascular complications include neuropathy, retinopathy, and diabetic kidney disease. Control of hypertension and dyslipidemia is an important step in minimizing the risk of complications. Blood pressure (BP) levels should be maintained at less than 140 mm Hg systolic and less than 90 mm Hg diastolic. In older adults, medical therapy to reduce BP to less than 130/70 mm Hg is not recommended. In these patients, a systolic BP level less than 130 mm Hg has not been shown to improve atherosclerotic cardiovascular disease (ASCVD) outcomes, and a diastolic BP less than 70 mm Hg is associated with a higher mortality risk...
May 2017: FP Essentials
https://www.readbyqxmd.com/read/28530382/diabetes-update-new-pharmacotherapy-for-type-2-diabetes
#17
Beth Choby
Multiple new drugs for managing type 2 diabetes have entered the market in the past 5 years. Guidelines from the American Diabetes Association recommend metformin for initial therapy, followed by a second drug if A1c goals are not met or initially for patients with A1c levels greater than 9%. Conversely, the American Association of Clinical Endocrinologists recommends initial management with two drugs if the A1c level is greater than 7.5%. The risk of lactic acidosis associated with metformin has been shown to be less than previously thought, with newer guidelines permitting use with an estimated glomerular filtration rate of 45 to 60 mL/min/1...
May 2017: FP Essentials
https://www.readbyqxmd.com/read/28530381/diabetes-update-risk-factors-screening-diagnosis-and-prevention-of-type-2-diabetes
#18
Beth Choby
Type 2 diabetes (T2D) is the result of insulin resistance. Significant differences are noted in the prevalence of T2D among races. Screening recommendations vary by subspecialty society. Asian Americans should be screened for T2D at a lower body mass index (BMI) (ie, 23 kg/m(2)) than other racial groups. Risk factors for T2D include high-risk ethnicity, obesity, taking of certain drugs (including statins), and gestational diabetes. Health disparities and genetics also influence risk of T2D, although these complexities continue to be poorly understood...
May 2017: FP Essentials
https://www.readbyqxmd.com/read/28530380/diabetes-update-primary-care-of-patients-with-type-1-diabetes
#19
Beth Choby
The incidence and prevalence of type 1 diabetes (T1D) are increasing among white, black, Hispanic, and Asian individuals in the United States. Children often present with acute symptoms, including severe polyuria, polydipsia, weight loss, and ketonemia; adults may develop more gradual symptoms that initially appear similar to those of type 2 diabetes (T2D). Latent autoimmune diabetes of adults and maturity-onset diabetes of the young are conditions that may be confused with T1D, although they are actually more closely related to T2D...
May 2017: FP Essentials
https://www.readbyqxmd.com/read/28530379/diabetes-update-foreword
#20
Kate Rowland
No abstract text is available yet for this article.
May 2017: FP Essentials
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