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https://www.readbyqxmd.com/read/29793112/3d-printed-membrane-as-an-alternative-to-amniotic-membrane-for-ocular-surface-conjunctival-defect-reconstruction-an-in-vitro-in-vivo-study
#1
Shima Dehghani, Morteza Rasoulianboroujeni, Hamed Ghasemi, Saeed Heidari Keshel, Zohreh Nozarian, Mohammad Naser Hashemian, Mehran Zarei-Ghanavati, Golshan Latifi, Reza Ghaffari, Zhanfeng Cui, Hua Ye, Lobat Tayebi
BACKGROUND: The aim of this study was to evaluate the surgical handling and clinical applicability of a specific 3D-printed membrane design fabricated using a gelatin, elastin and sodium hyaluronate blend for conjunctival reconstruction and compare it with amniotic membrane (AM), which is normally used in such surgeries. METHODS: 3D printing technique was employed to fabricate the membrane based on gradient design. Prior to printing, rheometry was employed to optimize the ink composition...
May 11, 2018: Biomaterials
https://www.readbyqxmd.com/read/29792846/adenosine-receptor-distribution-in-rhesus-monkey-ocular-tissue
#2
Krista M Beach, Li-Fang Hung, Baskar Arumugam, Earl L Smith, Lisa A Ostrin
Adenosine receptor (ADOR) antagonists, such as 7-methylxanthine (7-MX), have been shown to slow myopia progression in humans and animal models. Adenosine receptors are found throughout the body, and regulate the release of neurotransmitters such as dopamine and glutamate. However, the role of adenosine in eye growth is unclear. Evidence suggests that 7-MX increases scleral collagen fibril diameter, hence preventing axial elongation. This study used immunohistochemistry (IHC) and reverse-transcription quantitative polymerase chain reaction (RT-qPCR) to examine the distribution of the four ADORs in the normal monkey eye to help elucidate potential mechanisms of action...
May 21, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29791696/monocenter-experience-with-532-nm-laser-photoselective-vaporization-of-the-prostate-by-greenlight-xps%C3%A2-laser-is-it-really-an-endourological-joker-card
#3
Jamil Ghahhari, Carlo D'Orta, Ambra Rizzoli, Michele Marchioni, Giulia I Primicer, Piergustavo De Francesco, Angelo Civitella, Mario Di Lecce, Pietro Castellan, Roberto Castellucci, Fabio Neri, Fabiola Raffaella Tamburro, Luca Cindolo, Luigi Schips
INTRODUCTION: In our study, we reported on our monocenter experience with GreenLight (GL) Xcelerated Performance System (XPS)™ /MoXy™ laser fiber (American Medical Systems Inc., Minnetonka, Minnesota), examining its efficacy, safety, and its ability to effectively treat lower urinary tract symptoms (LUTS) in benign prostate obstruction (BPO). We also explored and compared the three different endoscopic approaches used for GL treatment of benign prostatic hyperplasia (BPH), standard photovaporization (PVP), anatomical PVP, and GreenLight XPS™ enucleation of the prostate...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29788760/regression-patterns-of-choroidal-melanoma-after-palladium-103-103-pd-plaque-brachytherapy
#4
Abhilasha Maheshwari, Paul T Finger
PURPOSE: To describe the patterns of regression of choroidal melanoma after treatment with plaque brachytherapy. METHODS: Retrospective interventional case series including 170 consecutive patients treated with 103 Pd eye plaque radiation for choroidal melanoma. Outcome measures were changes in tumor thickness, surface characteristics, tumor vascularity, ultrasonography, fluorescein angiography, optical coherence tomography, and histopathology. RESULTS: The mean initial tumor thickness was 3...
May 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29783002/a-stepwise-approach-to-laparoscopic-enucleation-and-excision-of-retroperitoneal-cysts
#5
Haider Jan, Tina Kapoor, Vishalli Ghai
STUDY OBJECTIVE: Technical video demonstrating a step by step approach to laparoscopic enucleation and excision of retroperitoneal cysts. DESIGN: Technical video (Canadian Task Force classification III). SETTING: Benign Gynecology Department at a University Hospital. INTERVENTION: Laparoscopic enucleation and excision of retroperitoneal cysts. CONCLUSION: Retroperitoneal cysts are rare lesions associated with numerous complications including compression on neighbouring organs, infection, rupture and malignant transformation...
May 18, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29780936/clinical-and-pathological-correlation-of-cotton-wool-spots-in-secondary-angle-closure-glaucoma
#6
Anand Bhatt, Christine Nguyen, Sameh Mosaed, Don Minckler
Purpose: Cotton Wool Spots (CWS) are a commonly described retinal finding in the posterior segment associated with an extensive number of systemic diseases. The appearance of a CWS in the setting of glaucoma has rarely been reported and has not been correlated with pathology to localized loss of the nerve fiber layer previously. In this case report, we augment a previous report of an 18 year old female with a diagnosis of low grade ciliary body melanoma. This patient experienced eventual mechanical angle closure with a CWS appearing in the posterior pole in the setting of acute elevation of intraocular pressure (IOP)...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29780913/cryptococcal-choroiditis-in-advanced-aids-with-clinicopathologic-correlation
#7
Christopher M Aderman, Ian R Gorovoy, Daniel L Chao, Michele M Bloomer, Anthony Obeid, Jay M Stewart
Purpose: To describe a case of disseminated cryptococcal meningitis with multifocal choroiditis and provide optical coherence tomography (OCT) findings correlated with described histopathology in a patient with advanced acquired immunodeficiency syndrome (AIDS). Observations: The patient was a 54-year-old man with AIDS who presented with dyspnea and headache followed by acute vision loss. OCT demonstrated a lesion with a small area of fluid that was limited by a more prominent and irregular external limiting membrane with underlying nodular choroidal thickening, mild RPE disorganization, and hyperreflectivity of the overlying photoreceptor layer...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29780912/orbital-implant-exposure-after-acanthamoeba-panophthalmitis
#8
Meredith S Baker, Amanda C Maltry, Nasreen A Syed, Richard C Allen
Purpose: Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male. Observations: After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis, and ultimately, required enucleation...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29775699/relationship-between-intraprostatic-urethral-sphincter-status-and-prostate-volume-as-revealed-by-magnetic-resonance-imaging
#9
Fumiyasu Endo, Kazuhiro Ohwaki, Masaki Shimbo, Kazunori Hattori
OBJECTIVES: To evaluate the relationship between the lengths of two regions of the intraprostatic urethral sphincter, the distal region (from the apex to the adenoma; AA) and the proximal region (from the adenoma to the verumontanum; AV) and prostate volume (PV) in patients with clinical benign prostate hyperplasia. METHODS: A total of 110 patients who underwent magnetic resonance imaging (MRI) prior to holmium laser enucleation of the prostate were enrolled. The lengths of two distinct intraprostatic urethral regions were measured on MRI, and we used multiple regression analysis to explore the association between these lengths and PV...
May 15, 2018: Urology
https://www.readbyqxmd.com/read/29774816/holmium-laser-enucleation-of-the-prostate
#10
Marcelino E Rivera, James E Lingeman, Amy E Krambeck
INTRODUCTION: Holmium laser enucleation of the prostate (HoLEP) offers superior voiding outcomes to traditional transurethral resection and less morbidity than open simple prostatectomy. Likewise, HoLEP has been determined to result in excellent outcomes regardless of gland size. We present a step-by-step surgical approach to HoLEP describing both the traditional enucleation technique and a modified "top-down" surgical technique. MATERIALS AND METHODS: In this video, two techniques are presented that were performed by two (A...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29773945/predictive-factors-in-the-treatment-of-streptococcal-endophthalmitis
#11
Yosanan Yospaiboon, Kidakarn Meethongkam, Suthasinee Sinawat, Wipada Laovirojjanakul, Tanapat Ratanapakorn, Thuss Sanguansak, Chavakij Bhoomibunchoo
Objective: To evaluate visual outcomes and possible predictive factors in the treatment of infectious endophthalmitis caused by Streptococcus species during 2012-2016 at a large referral eye center in northeastern Thailand. Methods: A retrospective medical record chart review of patients with culture-positive endophthalmitis caused by Streptococcus species was conducted. Demographic data including age, gender, occupation, duration of symptoms, time to surgery, surgical procedures, initial visual acuity at presentation, and final visual acuity after treatment were collected and analyzed...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29771404/mmp-2-participates-in-the-sclera-of-guinea-pig-with-form-deprivation-myopia-via-igf-1-stat3-pathway
#12
Y-X Liu, Y Sun
OBJECTIVE: To investigate the expression changes of MMP-2 (matrix metalloproteinases-2) mediated by IGF-1 (insulin-like growth factors-1) STAT3 (signal transducer and activator of transcription 3) pathway in the sclera of the form-deprivation myopia guinea pigs. MATERIALS AND METHODS: Twenty-four three-week-old guinea pigs were randomly divided into 4 groups: group A (Control), B, C and D. Guinea pigs in group A were sacrificed after 21 days without any special treatment...
May 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29768520/clinical-and-immunohistochemical-study-of-melanotic-neuroectodermal-tumor-of-infancy-in-the-maxilla
#13
Hellen Bandeira de Pontes Santos, Aníbal Henrique Barbosa de Luna, Pedro Everton Marques Goes, Alexander Tadeu Sverzut, Cassiano Francisco Weege Nonaka, Pollianna Muniz Alves
Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. The presumptive diagnoses were dentigerous cyst, adenomatoid odontogenic tumor, melanotic neuroectodermal tumor of infancy and rhabdomyosarcoma, and an incisional biopsy was performed...
May 14, 2018: Einstein
https://www.readbyqxmd.com/read/29765950/early-neuroblastic-and-astrocytic-differentiation-demonstrated-immunohistochemically-in-a-small-intraocular-medulloepithelioma
#14
Frederick A Jakobiec, Fouad R Zakka, Thanos Papakostas, Shizuo Mukai
Purpose: To investigate the source of fibrous astrocytes and neuroblasts in a small ciliary body medulloepithelioma appearing as a leukocoria in a 3-week-old baby girl. Methods: Histopathologic and immunohistochemical studies included Alcian blue, periodic acid-Schiff, and antisera for the detection of S100 protein, CD99, glial fibrillary acidic protein (GFAP), CRX, NeuN, neurofilaments, synaptophysin, desmin, and myogenin. Results: A small, nonteratoid ciliary body medulloepithelioma with collections of Alcian blue+ mucoplysaccharides was present in the enucleated globe...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29765946/radiation-retinopathy-47-years-following-brachytherapy-for-retinoblastoma
#15
Claudine Bellerive, Arun D Singh
A 50-year-old female who had undergone enucleation in the left eye and brachytherapy in the right eye for retinoblastoma at the age of 2 years was diagnosed with nonproliferation radiation retinopathy 47 years following the initial treatment. The patient had noticed black spots in her vision (scotomas) that interfered with reading. New onset of microaneurysms and lipid exudation threatening the foveola was noted on examination of the right eye. Initial visual acuity (VA) was 20/25. Optical coherence tomography showed no evidence of macular edema, but parafoveal lipid exudation was present...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29765221/surgical-treatment-of-an-esophageal-bronchogenic-cyst-with-massive-upper-digestive-tract-hematoma-without-esophagectomy-a-case-report-and-the-review-of-the-literature
#16
Yuanjun Cheng, Donglai Chen, Li Shi, Wentao Yang, Yonghua Sang, Shanzhou Duan, Yongbing Chen
Esophageal bronchogenic cysts are extremely rare. Here we report a case of massive upper digestive tract hematoma and bronchogenic cyst mimicking aortic dissection that was safely removed without esophagectomy. A 30-year-old man was referred to our hospital for the treatment of a mediastinal cystic tumor located in the submucosa of the distal esophagus. His chief complaints were dysphagia > 1 week and severe persistent upper abdominal pain mimicking aortic dissection with constant vomiting for 1 day after gastroscopy examination...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29764415/perioperative-outcomes-of-zero-ischemia-radiofrequency-ablation-assisted-tumor-enucleation-for-renal-cell-carcinoma-results-of-182-patients
#17
Chengwei Zhang, Xiaozhi Zhao, Suhan Guo, Changwei Ji, Wei Wang, Hongqian Guo
BACKGROUND: To evaluate the perioperative outcomes of zero ischemia radiofrequency ablation-assisted tumor enucleation. METHODS: Patients undergoing zero ischemia radiofrequency ablation-assisted tumor enucleation were retrospectively identified from July 2008 to March 2013. The tumor was enucleated after RFA treatment. R.E.N.A.L., PADUA and centrality index (C-index) score systems were used to assess each tumor case. We analyzed the correlation of perioperative outcomes with these scores...
May 15, 2018: BMC Urology
https://www.readbyqxmd.com/read/29763581/intraoperative-ultrasound-assisted-enucleation-of-residual-fibroids-following-laparoscopic-myomectomy
#18
Yan Hao, Si-Jing Li, Ping Zheng, Xia Wu, Jie Sheng, Dong-Lan Yuan, Qi Zhou, Wei Wei, Ai-Hong Duan, Qing-Qing Wu, Dan Lu
AIM: To investigate if intraoperative ultrasounds by laparoscopic and transvaginal ultrasonography (LUS and TVS) could improve enucleating the residual fibroids following laparoscopic myomectomy (LM). METHODS: From March to December 2016, 78 women with uterine fibroids underwent LM, LUS and TVS were applied to detect residual fibroids and to guide surgeons to enucleate them after the visible fibroids were removed during LM operation. RESULTS: The total number of residual fibroids found by LUS was 140, and the total number found by TVS was 127 following LM (P = 0...
May 12, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29762318/endoscopically-assisted-modified-caldwell-luc-approach-to-enucleation-of-dentigerous-cyst-with-ectopic-tooth-from-the-maxillary-sinus
#19
Isaac Liau, Nicholas Lynch, Brenton Hearn, Andrew Cheng
Dentigerous cysts in the craniomaxillofacial complex are a benign pathology commonly associated with ectopically placed teeth. Owing to slow and asymptomatic growth, they often attain considerable size before diagnosis that may compromise adjacent anatomical structures. Various techniques for removal of dentigerous cysts from the maxillary sinus have been described. This case report demonstrates a hybrid endoscopically assisted modification of the Caldwell-Luc approach to provide the technical advantages of both techniques...
May 14, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29757571/localized-chromophobe-renal-cell-carcinoma-preoperative-imaging-judgment-and-laparoscopic-simple-enucleation-for-treatment
#20
Wenbiao Ren, Bichen Xue, Jiandong Qu, Longfei Liu, Chao Li, Xiongbing Zu
OBJECTIVE: To evaluate the preoperative imaging manifestation and therapeutic effect of laparoscopic simple enucleation (SE) for localized chromophobe renal cell carcinoma (chRCC). MATERIALS AND METHODS: Clinical data of 36 patients who underwent laparoscopic SE of localized chRCC at our institute were retrospectively analyzed. All patients underwent preoperative renal protocol CT (unenhanced, arterial, venous, and delayed images). CT scan characteristics were evaluated...
April 30, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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