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https://www.readbyqxmd.com/read/28630790/rehabilitation-of-eyelid-malpositions-secondary-to-facial-palsy
#1
Şeyda Karadeniz Uğurlu, Mustafa Karakaş
OBJECTIVES: To evaluate patient satisfaction and outcomes of surgical treatment of eyelid malpositions secondary to facial palsy. MATERIALS AND METHODS: Consecutive patients with facial palsy who underwent surgical treatment by the same surgeon at İzmir Katip Çelebi University Atatürk Training and Research Hospital between Jan 2007 and Dec 2012 were included in the study. Ophthalmic examination findings, surgical approaches, and their outcomes were evaluated...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28625338/acute-diplopia-in-the-pediatric-emergency-department-a-cohort-multicenter-italian-study
#2
Umberto Raucci, Pasquale Parisi, Nicola Vanacore, Francesco La Penna, Valentina Ferro, Lucia Calistri, Claudia Bondone, Fabio Midulla, Agnese Suppiej, Raffaele Falsaperla, Duccio Maria Cordelli, Antonella Palmieri, Alberto Verrotti, Sabrina Becciani, Sonia Aguzzi, Mario Mastrangelo, Federica Pelizza, Filippo Greco, Giulia Carbonari, Ramona Tallone, Gabriella Bottone, Italo Trenta, Stefano Masi, Maria Pia Villa, Antonino Reale
BACKGROUND: Acute diplopia (AD) is an uncommon and distressing symptom of numerous ocular and neurological conditions, with potentially serious sequelaes. No data are present in pediatrics on the presentation and management of AD. AIM: This study investigated characteristics, etiology and health care utilization of the pediatric population with AD accessed to pediatric Emergency Departments (ED), trying to identify "red flags" associated with potentially life-threatening (LT) conditions...
June 3, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28623857/vincristine-induced-neuropathy-in-pediatric-patients-with-acute-lymphoblastic-leukemia-in-oman-frequent-autonomic-and-more-severe-cranial-nerve-involvement
#3
Hanan F Nazir, Amna AlFutaisi, Mathew Zacharia, Mohamed Elshinawy, Surekha T Mevada, Abdulhakim Alrawas, Doaa Khater, Deepali Jaju, Yasser Wali
BACKGROUND: Vincristine (VCR) induced peripheral neuropathy is a common complication in children with acute lymphoblastic leukemia (ALL). PROCEDURES: A retrospective data analysis over an interval of 10 years (2006-2016) of all children with ALL seen at Sultan Qaboos University Hospital was carried out. Electronic medical records of eligible patients were reviewed. Patients with clinical evidence of neuropathy and abnormal nerve conduction studies (NCSs) were included in the study...
June 17, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28620980/case-of-autoimmune-autonomic-ganglionopathy-manifesting-anhidrosis
#4
Asuka Yoshifuku, Koichi Yoneda, Yusuke Sakiyama, Osamu Higuchi, Shunya Nakane, Takuro Kanekura
Autoimmune autonomic ganglionopathy (AAG), clinically characterized by gastrointestinal dysmotility, orthostatic hypotension and tonic pupils, is an idiopathic acquired disorder of the autonomic nervous system elicited by antibodies against ganglionic acetylcholine receptor (gAChR). We encountered a 60-year-old man who presented with severe anhidrosis, difficulty in thermoregulation, orthostatic hypotension, gastrointestinal dysmotility, tonic pupils and ptosis. Histologically, an anhidrotic skin sample was normal...
June 16, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28615812/optimising-aesthetic-outcome-after-nipple-areola-complex-sparing-mastectomy-and-immediate-one-stage-prosthetic-reconstruction-a-simple-surgical-trick-to-fix-nipple-areola-complex-position
#5
Luca Maione, Andrea Lisa, Federico Barbera, Mattia Siliprandi, Valeriano Vinci, Francesco Klinger, Marco Klinger
BACKGROUND: Nipple-areola complex (NAC) sparing mastectomy (NSM) is mostly indicated in patients with small-/medium-sized and non-ptotic breasts, while skin-reducing mastectomy is used in patients with medium or large breasts with severe ptosis. NAC location on the reconstructed breast is one of the major factors in determining the final aesthetic result and patients' satisfaction. An optimum result obtained at the end of surgical procedure may be altered and compromised by skin redistribution and consequently NAC depositioning during the post-operative period in patients with medium-sized breasts and a moderate degree of ptosis...
January 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28614091/injectable-daxibotulinumtoxina-for-the-treatment-of-glabellar-lines-a-phase-2-randomized-dose-ranging-double-blind-multicenter-comparison-with-onabotulinumtoxina-and-placebo
#6
Jean Carruthers, Nowell Solish, Shannon Humphrey, Nathan Rosen, Channy Muhn, Vince Bertucci, Arthur Swift, Andrei Metelitsa, Roman G Rubio, Jacob Waugh, John Quiring, Gill Shears, Alastair Carruthers
BACKGROUND: Injectable daxibotulinumtoxinA (RT002) is an investigational botulinum toxin Type A in clinical development. It is formulated with a proprietary peptide and offers the potential of a longer acting neurotoxin therapy. OBJECTIVE: To compare the safety, efficacy, and duration of response of daxibotulinumtoxinA with onabotulinumtoxinA and placebo [www.clinicaltrials.gov NCT02303002]. METHODS: In this Phase 2, randomized, dose-ranging, parallel-group, double-blind, multicenter study, subjects with moderate or severe glabellar lines at maximum frown were randomly assigned to 20U, 40U, or 60U daxibotulinumtoxinA, 20U onabotulinumtoxinA, or placebo...
June 12, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28610808/sarcoidosis-of-the-lacrimal-gland-as-a-first-manifestation
#7
M Y Peralta-Gómez, K A Ávila-Ocampo, S Huerta-Velázquez, M I Rivera-Salgado
OBJECTIVE/METHOD: The first manifestation of sarcoidosis is usually at the pulmonary level. The case is described of a 40-year-old female patient, who presented with an increased volume of the lacrimal gland and mechanical ptosis of upper left eyelid as the first expression of this disease. RESULT/CONCLUSION: The diagnosis of systemic sarcoidosis with primary presentation of the lacrimal gland was made after performing several immunological studies with negative results, imaging studies, and taking of glandular and lymph node biopsies...
June 10, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28604951/-analysis-of-foxl2-gene-mutations-in-5-families-affected-with-blepharophimosis-ptosis-and-epicanthus-inversus-syndrome
#8
Xiaowen Yang, Wen Li, Juan Du, Shimin Yuan, Wenbin He, Qianjun Zhang, Changgao Zhong, Guangxiu Lu, Yueqiu Tan
OBJECTIVE: To screen for FOXL2 gene mutations in 6 patients with blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES), and explore their genotype-phenotype correlation. METHODS: Peripheral venous blood samples were collected from the patients for the extraction of genomic DNA. PCR and Sanger sequencing were employed to analyze the coding region and flanking sequences of the FOXL2 gene. Pathogenicity of the identified mutations was verified through literature review and bioinformatic analysis...
June 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28601853/incomplete-miller-fisher-syndrome-with-advanced-stage-burkitt-lymphoma
#9
Zeynep Canan Özdemir, Yeter Düzenli Kar, Coþkun Yarar, Suzan Þaylýsoy, Özcan Bör
BACKGROUND: Lymphoma-associated incomplete Miller-Fisher syndrome is very rare. CASE CHARACTERISTICS: An 11-year-old boy who initially presented with headache, left ptosis, diplopia and weakness. Neurologic examination indicated left sided ptosis with ophthalmoplegia. OBSERVATIONS: Cerebral imaging and cerebrospinal fluid examinations were normal. Magnetic resonance imaging of the abdomen showed a mass lesion in the ileal loops. A bone marrow biopsy showed infiltration by Burkitt's lymphoma...
May 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28601810/pattern-of-ocular-involvement-in-myasthenia-gravis-with-musk-antibodies
#10
Amelia Evoli, Paolo E Alboini, Raffaele Iorio, Valentina Damato, Emanuela Bartoccioni
BACKGROUND: Myasthenia gravis (MG) with antibodies to the muscle-specific kinase (MuSK) has a characteristic phenotype. Ocular manifestations have not been systematically evaluated. OBJECTIVE: To investigate the features of extrinsic ocular muscle involvement in patients with MuSK-MG. METHODS: We retrospectively evaluated the prevalence, time of onset, clinical pattern and outcome of ocular symptoms in 82 patients with a clinical follow-up ≥2 years...
June 10, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28601797/ptosis-as-a-complication-of-kawasaki-disease
#11
Ammar Hameed, Hassan Alshara, Thomas Schleussinger
Kawasaki disease is an acute febrile exanthematous disease that affects children younger than 5 years of age. It is regarded as the most common cause of childhood acquired heart disease, but ocular and neurological problems are among the other important clinical findings. We present a 3-year-old boy who developed bilateral ptosis on day 21, 5 days after intravenous immunoglobulin. The ptosis was due to bilateral paralysis of the levator palpebrae superioris muscles and resolved spontaneously on day 25. There were no cardiac sequelae...
June 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28594300/pre-operative-experiences-and-post-operative-benefits-of-ptosis-surgery-a-qualitative-study
#12
Hollie S Richards, Elizabeth Jenkinson, Nicola Rumsey, Richard A Harrad
This qualitative study sought to explore the experiences of patients who had undergone successful ptosis correction surgery. Participants were recruited from Bristol Eye Hospital. Nine participants were interviewed using a semi-structured interview schedule and open ended questions. Data were analysed using inductive thematic analysis. Four major themes were identified from patient accounts. Patients described the psychosocial and functional difficulties they experienced living with ptosis, and the subsequent benefits of surgery...
June 2017: Orbit
https://www.readbyqxmd.com/read/28593490/stenotic-breast-malformation-and-its-reconstructive-surgical-correction-a-new-concept-from-minor-deformity-to-tuberous-breast
#13
Marco Klinger, Francesco Klinger, Silvia Giannasi, Alessandra Veronesi, Valeria Bandi, Barbara Banzatti, Barbara Catania, Valeriano Vinci, Andrea Lisa, Guido Cornegliani, Micol Giaccone, Fabio Caviggioli, Luca Maione
BACKGROUND: Several classification systems have been reported to define the spectrum of tuberous breast deformity, and a range of surgical techniques has been described. In this paper, we proposed a new classification including tuberous breast and minor deformity based on stenosis type, glandular trophism and ptosis adapting surgical planning to different breast types. METHODS: A total of 246 patients meeting our definition for stenotic breasts asking for surgery were analyzed in this study...
June 7, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28588873/a-72-year-old-with-eyelid-opening-apraxia-in-steele-richardson-olszewski-syndrome
#14
Ihtesham A Qureshi, Mohtashim A Qureshi, Alberto Maud
In our patient with Steele-Richardson-Olszewski syndrome presenting with apraxia of eyelid opening, there is a possibility to be readily confused with conditions presenting in similar pattern such as blepharospasm and eyelid ptosis. Therefore, it is essential to correlate the clinical findings with electromyographic recordings and dopamine transporter scan (DaT).
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28586604/orbital-involvement-in-sinonasal-diseases
#15
Zia-Us-Salam Qazi, Sarfraz Latif, Sadia Maqsood Awan
OBJECTIVE: Orbital involvement in sinonasal diseases can present as proptosis, ophthalmoplegia or even as blindness due to optic nerve damage. There are a number of sinonasal diseases which can involve eyes. The purpose of this study was to enlist diagnoses of all the patients with sinonasal disease, in which orbit was also involved unilaterally or bilaterally and to analyse the management strategy and final outcome in all the cases. METHODS: Hundred consecutive patients having orbital symptoms along with sinonasal complaints that presented in ENT department of Shaikh Zayed federal postgraduate medical institute were included in our prospective study...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28585887/symptomatic-ptosis-cerebelli-after-suboccipital-craniectomy-in-a-patient-with-severe-brain-trauma
#16
Ana M Castaño-Leon, Santiago Cepeda, Igor Paredes, Pedro A Gómez, Luis Jiménez-Roldán, Alfonso Lagares, Angel Pérez-Núñez
PRIMARY OBJECTIVE: To report the first case of symptomatic cerebellar ptosis after a large suboccipital craniectomy in a patient with severe brain trauma and a review of the literature. PATIENT AND METHODS: A 36-year-old man suffered severe traumatic brain injury after a four-metre fall. He underwent a large suboccipital craniectomy because his computed tomography scan revealed a posterior fossa subdural haematoma and cerebellar swelling. Four weeks after admission, he developed communicating hydrocephalus, and a ventriculoperitoneal shunt was placed...
June 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28584812/upper-eyelid-silicone-oil-migration-after-sutureless-23-gauge-vitrectomy
#17
Alireza Dehghani, Leila Rezaei, Ali Tavallali, Zahra Dastborhan
To report a case of upper eyelid swelling and ptosis caused by silicone oil migration in a patient after sutureless 23-gauge pars plana vitrectomy and silicone oil injection. A 36-year-old female was referred to eye clinic with total retinal detachment (RD) and superotemporal giant dialysis secondary to trauma in the left eye. Transconjunctival sutureless 23-gauge pars plana vitrectomy and intraocular silicone oil (1300 centistokes) injection were performed. After about 5 months, she came back with the left upper eyelid and periorbital swelling...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28584563/the-relationship-of-amount-of-resection-and-time-for-recovery-of-bell-s-phenomenon-after-levator-resection-in-congenital-ptosis
#18
Ruchi Goel, Divya Kishore, Smriti Nagpal, Sparshi Jain, Tushar Agarwal
BACKGROUND: Recovery of Bell`s phenomenon after levator resection is unpredicatable. Delayed recovery can result in vision threatening corneal complications. AIM: To study the variability of Bell's phenomenon and time taken for its recovery following levator resection for blepharoptosis and to correlate it with the amount of resection. METHODS: A prospective observational study was conducted on 32 eyes of 32 patients diagnosed as unilateral simple congenital blepharoptosis who underwent levator resection at a tertiary care center between July 2013 and May 2015...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28583577/antagonism-of-orexin-type-1-receptors-ox1rs-attenuates-naloxone-precipitated-morphine-withdrawal-syndrome-in-rat-dorsal-hippocampus
#19
Mehdi Hooshmandi, Narges Hosseinmardi, Mahyar Janahmadi, Fatemeh Khakpai, Kambiz Rohampour, Jafar Doostmohammadi
Herein the effect of hippocampal orexin type-1 receptors (OX1Rs) blockade on morphine withdrawal syndrome was studied. Animals were made dependent by subcutaneous (s.c.) administration of morphine sulfate (10mg/kg) at an interval of 12h for 9 consecutive days. Thereafter, on day 10, naloxone hydrochloride (1.5mg/kg, i.p.) was injected and the somatic signs of withdrawal syndrome were monitored during a 25-min period. Two groups of animals received bilateral microinjection of either SB-334867, a selective OX1Rs antagonist, (0...
July 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28582369/comparison-of-revision-rates-of-anterior-and-posterior-approach-ptosis-surgery-a-retrospective-review-of-1519-cases
#20
Eva Chou, Jun Liu, Cathleen Seaworth, Meredith Furst, Malena M Amato, Sean M Blaydon, Vikram D Durairaj, Tanuj Nakra, John W Shore
PURPOSE: To compare revision rates for ptosis surgery between posterior-approach and anterior-approach ptosis repair techniques. METHODS: This is the retrospective, consecutive cohort study. All patients undergoing ptosis surgery at a high-volume oculofacial plastic surgery practice over a 4-year period. A retrospective chart review was conducted of all patients undergoing posterior-approach and anterior-approach ptosis surgery for all etiologies of ptosis between 2011 and 2014...
June 2, 2017: Ophthalmic Plastic and Reconstructive Surgery
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