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https://www.readbyqxmd.com/read/28931192/markers-of-proliferation-and-cytokeratins-in-the-differential-diagnosis-of-jaw-cysts
#1
Nikola D Živković, Dragan S Mihailović, Miloš S Kostić, Ana S Cvetanović, Žaklina Ž Mijović, Maja V Milentijević, Tijana V Denčić
We conducted a retrospective study to analyze the histologic and immunohistochemical findings in three main types of odontogenic cyst. We studied 90 archived cystic jaw lesions: 30 dentigerous cysts, 30 keratocystic odontogenic tumors, and 30 radicular cysts. The cyst types were identified on the basis of clinical, radiologic, and histopathologic findings. Immunohistochemical analyses included staining with Ki-67, p53, epidermal growth factor receptor (EGFR), cytokeratin (CK) 8, CK14, CK17, and CK18. Cell immunopositivity was evaluated for the entire epithelium...
September 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28928922/liver-transplantation-as-definitive-treatment-of-an-unresectable-mesenchymal-hamartoma-in-a-child-with-beckwith-wiedemann-syndrome
#2
Evelyn T Pan, Dor Yoeli, Michael L Kueht, N Thao N Galvan, Ronald T Cotton, Christine A O'Mahony, Abbas Rana, John A Goss
Mesenchymal liver hamartomas are benign tumors that can cause life-threatening abdominal distension and carry a risk for malignant transformation. In this case report, we describe a 13-month-old male with Beckwith-Wiedemann Syndrome (BWS) who presented with multiple mesenchymal liver hamartomas causing severe intra-abdominal mass effect. Imaging revealed six large multi-locular cystic lesions, ranging from 3.8 to 8.9 cm in diameter. The large size and spread of the tumors necessitated liver transplantation for complete removal...
August 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28926383/mri-findings-in-patients-after-small-head-metal-on-metal-total-hip-arthroplasty-with-a-minimum-follow-up-of-10-years
#3
Tobias Reiner, Thuy D Do, Matthias C Klot, Fabian Hertzsch, Kirsten Seelmann, Matthias M Gaida, Marc-André Weber, Tobias Gotterbarm
BACKGROUND: Concern has been raised about the late onset of adverse reactions to metal debris (ARMD) in patients with a small-head metal-on-metal total hip replacement. The aims of this study were to assess the frequency and characteristic appearance of ARMD in patients with a small-head (28-mm) metal-on-metal total hip replacement and elevated blood ion levels (>1 μg/L) after a minimum follow-up of 10 years and to analyze the possible risk factors associated with the prevalence of these lesions...
September 20, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28925089/lipofuscin-deposition-causes-the-pigmentation-of-apocrine-hidrocystoma
#4
Shinya Kitamura, Teruki Yanagi, Keisuke Imafuku, Hiroo Hata, Hiroshi Shimizu
Apocrine hidrocystoma (AHC) is a benign cystic lesion arising from apocrine glands and frequently presents as a blue hae with a whitish gloss. It has been reported that the amount of lipofuscin and the degree of its oxidation determines the pigmentation of AHC. However, little is known about the correlation between clinical color and lipofuscin granules. In this study, we histopathologically investigated three cases of AHC and statistically analyzed the quantitative correlation between the clinical color tone and the amount of cytoplasmic lipofuscin deposits...
September 18, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28924108/proton-pump-inhibitor-induction-of-gastric-cobblestone-like-lesions-in-the-stomach
#5
Kosuke Takahari, Ken Haruma, Hiroshi Ohtani, Sho Kiyoto, Akifumi Watanabe, Tomoari Kamada, Noriaki Manabe, Yu Hatano
Objective The long-term use of proton pump inhibitors (PPIs) may induce adverse events in many organs, including the stomach. The chronic use of PPIs has been associated with the growth of fundic gland polyps (FGPs) and of gastric black spots. This study assessed the incidence of gastric lesions with cobblestone-like appearance in PPI users. Methods The clinical characteristics and endoscopic findings of patients who underwent upper gastrointestinal endoscopy after using PPIs for at least six months were analyzed...
September 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28922881/intraoperative-flow-800-analysis-for-intramedullary-cystic-lesion-a-technical-case-report
#6
Masahiro Sawada, Toshihiro Munemitsu, Masato Hojo
BACKGROUND AND IMPORTANCE: During intramedullary lesion surgery, the lesion site and the posterior median sulcus (PMS) should be accurately identified prior to myelotomy to avoid severe injury of the posterior funiculus. However, intramedullary lesions are fundamentally invisible until the myelotomy is performed. Furthermore, the PMS location is frequently unclear due to lesion-induced swelling or distortion of the spinal cord. Intraoperative indocyanine green videoangiography (ICG-VA) followed by FLOW 800 analysis, which shows vascularization of the spinal parenchyma, may provide a solution for these problems in specific cases...
October 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28918811/future-directions-for-endoscopic-ultrasound-where-are-we-heading
#7
REVIEW
Sahin Coban, Omer Basar, William R Brugge
Endoscopic ultrasound (EUS) plays an important role as a diagnostic and therapeutic modality in gastroenterology. New developments have emerged, especially in the last decade, and are being introduced to endoscopists. The ability to readily visualize and access organs in the gastrointestinal tract has allowed endoscopists to perform new interventional procedures. EUS procedures have taken the place of conventional approaches for the treatment of various gastrointestinal diseases, including pancreatic cystic lesions...
October 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28918802/endoscopic-ultrasound-imaging-for-diagnosing-and-treating-pancreatic-cysts
#8
REVIEW
Wiriyaporn Ridtitid, Mohammad A Al-Haddad
Cystic pancreatic lesions are increasingly diagnosed owing to the abundant use of cross-sectional imaging. Given their malignant potential, true pancreatic cysts should be considered for resection or periodic follow-up. Cystic lesions of the pancreas (CLPs) require further evaluation and management. Therefore, it is important to establish a solid diagnosis at the time of detection. Endoscopic ultrasound examination is the imaging modality of choice. Fine needle aspiration provides fluid for cytologic, biochemical, and molecular assays to classify lesions and predict biological behavior...
October 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28914672/endometrial-changes-in-surgical-specimens-of-perimenopausal-patients-treated-with-ulipristal-acetate-for-uterine-leiomyomas
#9
Francisco F Nogales, Vicente Crespo-Lora, Nelly Cruz-Viruel, Clara Chamorro-Santos, Christine Bergeron
Ulipristal acetate (UPA) is used to treat leiomyomas, and its effect on the endometrium has been studied in biopsy material. Reversible histologic modifications were found, named progesterone receptor modulators-associated endometrial changes (PAEC). However, hysterectomies from patients treated with UPA have not been analyzed. For the first time, we examined surgical specimens from 100 leiomyoma-treated patients for UPA-related endometrial changes. We analyzed the distribution of lesions, involution after treatment, and the relationship between type and extent of lesions and dosage...
September 13, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28914584/circumferential-ciliary-body-cysts-presenting-as-acute-pigment-dispersion-and-ocular-hypertension
#10
Almila Sarıgül Sezenöz, Sirel Gür Güngör, Hayyam Kıratlı, Ahmet Akman
PURPOSE: To report a case of circumferential neuroepithelial cyst of the ciliary body presenting with pigment dispersion (PD) and ocular hypertension. CASE REPORT: 48-year-old female patient presented with a complaint of pain in the left eye. On examination, visual acuity of the left eye was 0.9, and the intraocular pressure was 48 mmHg. Biomicroscopic anterior segment examination of the left eye revealed 4+ pigmented cells in the anterior chamber. Active PD from the pupillary region at 11 o'clock was noticed at the time of the examination...
September 15, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28913933/diagnostic-accuracy-of-fnac-and-cyto-histopathological-correlation-in-testicular-and-paratesticular-mass-lesions
#11
A D Singh, F A Wani, S Bhardwaj
OBJECTIVE: FNAC has a definitive role and has proved extremely useful in diagnosis of testicular and paratesticular mass lesions. In view of the dearth of literature of studies involving large cohorts of patients, the present study describes at length the detailed cytological evaluation of testicular and paratesticular mass lesions. METHODS: Our study consisted of 85 cases in 5-year retrospective and 1-year prospective analyses carried out in the Department of Pathology, Government Medical College, Jammu...
September 15, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28913716/a-case-of-a-mucin-producing-bile-duct-tumor-diagnosed-over-the-course-of-6%C3%A2-years
#12
Sho Yamada, Yosuke Kato, Masahiro Hada, Masanori Kotake, Kaeko Oyama, Takuo Hara
We report a case of a mucin-producing intraductal papillary neoplasm of the intrahepatic bile duct (M-IPNB) diagnosed over a period of 6 years. A 64-year-old man underwent follow-up evaluations for an abdominal aortic aneurysm at our hospital. In 2009, a computed tomography (CT) scan revealed a simple hepatic cyst in segment 3 of the liver. Annual CT scans initially showed almost no change in the size or shape of the cyst. The cystic lesion, which measured 5 cm in 2014, had increased to 11 cm by 2015, and a solid component was detected within the cyst...
September 14, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28905844/metastatic-renal-cell-carcinoma-presenting-as-one-and-a-half-syndrome
#13
Mukesh Patil, Anita Ganger, Sanjay Sharma, Rohit Saxena
We report a case of 43-year-old male, presented with sudden onset binocular diplopia on lateral gazes. Ocular examination showed features of ipsilateral one-and-a-half syndrome. Comprehensive systemic work in conjunction with magnetic resonance imaging of the brain illustrated irregular mixed solid and cystic lesions in the brainstem, possibly indicative of brain metastases. Further imaging revealed hidden renal cell carcinoma as a primary neoplasm, which led to secondary manifestations.
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905840/giant-eyelid-eccrine-hidrocystoma-induced-progressive-ptosis-in-childhood
#14
Dhivya Ashok Kumar, Amar Agarwal
An upper lid eccrine hidrocystoma presenting as early childhood progressive ptosis is very rare. We present a 9-year-old female child with droopy right upper lid since birth and progressive increase in symptoms. She had right upper lid ptosis (marginal reflex distance 1 of -1 mm) with fair levator function (8 mm) and abnormal cystic change on the conjunctival side. Computerized tomography imaging delineated the well-defined cystic lesion with homogeneous cavity with no contrast enhancement. Following the cyst excision, a giant eccrine hidrocystoma measuring 25 mm × 15 mm was removed, the largest reported in pediatric eyes...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28904578/rosette-forming-glioneuronal-tumor-a-rare-posterior-fossa-tumor-in-an-adolescent
#15
Goutam Bera, Amitabha Das, Sandip Chatterjee, Uttara Chatterjee
Rosette-forming glioneuronal tumor (RGNT) is a rare variety of slow growing mixed glioneuronal tumor involving primarily fourth ventricular region and occurring predominantly in young adults. We present a case of a 16-year-old boy who presented with dizziness and occipital headache. On radiological evaluation, a fairly large hypodense posterior fossa mass lesion in relation to the left side of the vermis, with a large cystic component was found. Surgical resection of the tumor was performed. Histopathological examination showed a biphasic tumor composed of bland neurocytic cells, arranged in the form of neurocytic rosettes along with glial areas resembling low-grade glioma...
April 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28904353/toll-like-receptor%C3%A2-2-induced-cytotoxic-t-lymphocyte-associated-protein%C3%A2-4-regulates-aspergillus-induced-regulatory-t-cells-with-pro-inflammatory-characteristics
#16
Ruud P H Raijmakers, Evelien G G Sprenkeler, Floor E Aleva, Cor W M Jacobs, Thirumala-Devi Kanneganti, Leo A B Joosten, Frank L van de Veerdonk, Mark S Gresnigt
Patients with cystic fibrosis, chronic obstructive pulmonary disease, severe asthma, pre-existing pulmonary lesions, and severely immunocompromised patients are susceptible to develop infections with the opportunistic pathogenic fungus Aspergillus fumigatus, called aspergillosis. Infections in these patients are associated with persistent pro-inflammatory T-helper (TH)2 and TH17 responses. Regulatory T-cells, natural suppressor cells of the immune system, control pro-inflammatory T-cell responses, but can also contribute to disease by shifting to a pro-inflammatory TH17-like phenotype...
September 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28900835/osteitis-fibrosa-cystica-a-forgotten-radiological-feature-of-primary-hyperparathyroidism
#17
Waldemar Misiorowski, Izabela Czajka-Oraniec, Magdalena Kochman, Wojciech Zgliczyński, John P Bilezikian
Although bone disease and stone disease are the universally accepted classical manifestations of primary hyperparathyroidism, clinical parathyroid bone disease is rarely seen today in the United States (<5% of patients) and Western Europe. Nevertheless, in a given patient, classical skeletal involvement can be the first sign of primary hyperparathyroidism, but not recognized because it is not usually included, anymore, in the differential diagnosis of this manifestation of skeletal disease. We describe four cases of primary hyperparathyroidism in which the first clinical manifestation of the disease was a pathological fracture that masqueraded as a malignancy...
September 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28899426/benign-metastasizing-leiomyoma-presenting-as-multiple-cystic-pulmonary-nodules-a-case-report
#18
Yeong Hun Choe, So Yeon Jeon, Yoon Chae Lee, Myung Ja Chung, Seung Yong Park, Yong Chul Lee, So Ri Kim
BACKGROUND: Benign metastatic leiomyoma (BML) is an extremely rare disease. Although uterine leiomyomas are benign histologically, they can metastasize to distant sites. While the incidence is very low, the lung is the organ most frequently affected by BML. Pulmonary BML usually presents as numerous well-defined nodules of various sizes, while the cavitary or cystic features in the nodules are rarely observed on radiologic images. CASE PRESENTATION: A 52-year-old woman complained of cough and dyspnea for one month...
September 12, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28898917/technical-aspects-of-endoscopic-ultrasound-eus-guided-sampling-in-gastroenterology-european-society-of-gastrointestinal-endoscopy-esge-technical-guideline-march-2017
#19
Marcin Polkowski, Christian Jenssen, Philip Kaye, Silvia Carrara, Pierre Deprez, Angels Gines, Gloria Fernández-Esparrach, Pierre Eisendrath, Guruprasad P Aithal, Paolo Arcidiacono, Marc Barthet, Pedro Bastos, Adele Fornelli, Bertrand Napoleon, Julio Iglesias-Garcia, Andrada Seicean, Alberto Larghi, Cesare Hassan, Jeanin E van Hooft, Jean-Marc Dumonceau
For routine EUS-guided sampling of solid masses and lymph nodes (LNs) ESGE recommends 25G or 22G needles (high quality evidence, strong recommendation); fine needle aspiration (FNA) and fine needle biopsy (FNB) needles are equally recommended (high quality evidence, strong recommendation).When the primary aim of sampling is to obtain a core tissue specimen, ESGE suggests using 19G FNA or FNB needles or 22G FNB needles (low quality evidence, weak recommendation).ESGE recommends using 10-mL syringe suction for EUS-guided sampling of solid masses and LNs with 25G or 22G FNA needles (high quality evidence, strong recommendation) and other types of needles (low quality evidence, weak recommendation)...
September 12, 2017: Endoscopy
https://www.readbyqxmd.com/read/28893324/selecting-treatment-method-for-ovarian-masses-in-children-24%C3%A2-years-of-experience
#20
Justyna Łuczak, Maciej Bagłaj
BACKGROUND: Epidemiology and pathology of ovarian tumors in the pediatric population are very different of these encountered in women. Few attempts have been made to analyze the whole spectrum of ovarian pathology in children, and only some of them included series of more than 200 cases. We performed a retrospective analysis of clinical and diagnostic aspects of ovarian tumors and tumor-like lesions in girls in order to identify the characteristics associated with malignancy with an attempt to elaborate a clinical management algorithm...
September 11, 2017: Journal of Ovarian Research
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