keyword
MENU ▼
Read by QxMD icon Read
search

First episode psychosis

keyword
https://www.readbyqxmd.com/read/28448805/the-associations-between-quality-of-life-and-clinical-symptoms-in-individuals-with-an-at-risk-mental-state-and-first-episode-psychosis
#1
Noriyuki Ohmuro, Kazunori Matsumoto, Yu Ishii, Masahiro Katsura, Chika Obara, Tatsuo Kikuchi, Yumiko Hamaie, Fumiaki Ito, Hiroo Matsuoka
Quality of life (QOL) is strongly associated with severity of clinical symptoms and is often compromised in patients with chronic or first-episode psychosis (FEP). However, it remains unclear whether baseline QOL in individuals with an at-risk mental state (ARMS) for psychosis is higher or lower than that in patients with FEP, or what specific clinical symptoms relate to a decreased QOL in individuals with ARMS and FEP. The World Health Organization's WHOQOL-BREF, an instrument assessing QOL, was administered to 104 individuals with ARMS and 53 with FEP...
April 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28442250/analysis-of-microbiota-in-first-episode-psychosis-identifies-preliminary-associations-with-symptom-severity-and-treatment-response
#2
Emanuel Schwarz, Johanna Maukonen, Tiina Hyytiäinen, Tuula Kieseppä, Matej Orešič, Sarven Sabunciyan, Outi Mantere, Maria Saarela, Robert Yolken, Jaana Suvisaari
The effects of gut microbiota on the central nervous system, along its possible role in mental disorders, have received increasing attention. Here we investigated differences in fecal microbiota between 28 patients with first-episode psychosis (FEP) and 16 healthy matched controls and explored whether such differences were associated with response after up to 12months of treatment. Numbers of Lactobacillus group bacteria were elevated in FEP-patients and significantly correlated with severity along different symptom domains...
April 22, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28437056/psychotic-and-bipolar-disorders-schizophrenia
#3
Alaina L Edmunds
Schizophrenia is the most common psychotic illness, typically appearing between the late teenage years and the mid-30s. The first episode of psychosis may be preceded by a prodromal period. Schizophrenia symptoms fall into six common symptom clusters: delusions and hallucinations, disorganization of speech, cognitive dysfunction, negative symptoms, affective symptoms, and motor system abnormalities. The diagnosis is based on criteria in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, including exclusion of other possible medical or psychiatric etiologies of psychosis...
April 2017: FP Essentials
https://www.readbyqxmd.com/read/28436349/distress-psychotic-symptom-exacerbation-and-relief-in-reaction-to-talking-about-trauma-in-the-context-of-beneficial-trauma-therapy-perspectives-from-young-people-with-post-traumatic-stress-disorder-and-first-episode-psychosis
#4
Janet Tong, Katrina Simpson, Mario Alvarez-Jimenez, Sarah Bendall
BACKGROUND: Of young people with first episode psychosis (FEP), over half report exposure to childhood trauma and consequent co-morbid post-traumatic stress disorder (PTSD) or symptoms. Currently no evidence-based interventions exist for PTSD in FEP. Clinicians report concerns that trauma-focused interventions with young people with FEP could result in distress and symptom exacerbation. Scant research suggests that talking about trauma in therapy can be distressing for some people. AIMS: To explore young people's reactions to a trauma-focused treatment for PTSD in FEP...
April 24, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28436345/evidence-that-polygenic-risk-for-psychotic-disorder-is-expressed-in-the-domain-of-neurodevelopment-emotion-regulation-and-attribution-of-salience
#5
J van Os, Y van der Steen, Md A Islam, S Gülöksüz, B P Rutten, C J Simons
BACKGROUND: The liability-threshold model of psychosis risk predicts stronger phenotypic manifestation of the polygenic risk score (PRS) in the healthy relatives of patients, as compared with healthy comparison subjects. METHODS: First-degree relatives of patients with psychotic disorder (871 siblings and 812 parents) and healthy comparison subjects (n = 523) were interviewed three times in 6 years. Repeated measures of two psychosis phenotypes, the Community Assessment of Psychic Experiences (CAPE; self-report - subscales of positive, negative and depressive symptoms) and the Structured Interview for Schizotypy - Revised (SIS-R; clinical interview - subscales of positive and negative schizotypy), were examined for association with PRS...
April 24, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28436341/insular-pathology-in-young-people-with-high-functioning-autism-and-first-episode-psychosis
#6
M Parellada, L Pina-Camacho, C Moreno, Y Aleman, M-O Krebs, M Desco, J Merchán-Naranjo, A Del Rey-Mejías, L Boada, C Llorente, D Moreno, C Arango, J Janssen
BACKGROUND: Autism Spectrum Disorders (ASD) and psychosis share deficits in social cognition. The insular region has been associated with awareness of self and reality, which may be basic for proper social interactions. METHODS: Total and regional insular volume and thickness measurements were obtained from a sample of 30 children and adolescents with ASD, 29 with early onset first-episode psychosis (FEP), and 26 healthy controls (HC). Total, regional, and voxel-level volume and thickness measurements were compared between groups (with correction for multiple comparisons), and the relationship between these measurements and symptom severity was explored...
April 24, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28427286/incomes-and-outcomes-social-security-disability-benefits-in-first-episode-psychosis
#7
Robert A Rosenheck, Sue E Estroff, Kyaw Sint, Haiqun Lin, Kim T Mueser, Delbert G Robinson, Nina R Schooler, Patricia Marcy, John M Kane
OBJECTIVE: Social Security Administration (SSA) disability benefits are an important source of income for people with psychoses and confer eligibility for health insurance. The authors examined the impact of coordinated specialty care on receipt of such benefits in first-episode psychosis, along with the correlates and consequences of receiving them. METHOD: The Recovery After an Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP) study, a 34-site cluster-randomized trial, compared NAVIGATE, a coordinated specialty care program, to usual community care over 2 years...
April 21, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28424105/specific-impact-of-stimulant-alcohol-and-cannabis-use-disorders-on-first-episode-psychosis-2-year-functional-and-symptomatic-outcomes
#8
C Ouellet-Plamondon, A Abdel-Baki, É Salvat, S Potvin
BACKGROUND: Many studies have concluded that cannabis use disorder (CUD) negatively influences outcomes in first-episode psychosis (FEP). However, few have taken into account the impact of concurrent misuse of other substances. METHODS: This 2-year, prospective, longitudinal study of FEP patients, aged between 18 and 30 years, admitted to early intervention programs in Montreal, Quebec, Canada, examined the specific influence of different substance use disorders (SUD) (alcohol, cannabis, cocaine, amphetamines) on service utilization, symptomatic and functional outcomes in FEP...
April 20, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28421012/moderated-online-social-therapy-a-model-for-reducing-stress-in-carers-of-young-people-diagnosed-with-mental-health-disorders
#9
John Gleeson, Reeva Lederman, Peter Koval, Greg Wadley, Sarah Bendall, Sue Cotton, Helen Herrman, Kingsley Crisp, Mario Alvarez-Jimenez
Family members caring for a young person diagnosed with the onset of mental health problems face heightened stress, depression, and social isolation. Despite evidence for the effectiveness of family based interventions, sustaining access to specialist family interventions is a major challenge. The availability of the Internet provides possibilities to expand and sustain access to evidence-based psychoeducation and personal support for family members. In this paper we describe the therapeutic model and the components of our purpose-built moderated online social therapy (MOST) program for families...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28419824/effect-of-risperidone-on-serum-homocysteine-levels-in-first-episode-drug-na%C3%A3-ve-patients-with-schizophrenia
#10
Ning Fan, Yunlong Tan, Fude Yang, Li Tian, Song Chen, Jia Li, Zhiren Wang, Xiangyang Zhang
Some studies have shown that homocysteine (Hcy) levels are increased in patients with schizophrenia, and may be involved in its pathophysiology. The purpose of this study was to investigate the effect of the atypical antipsychotic drug risperidone on serum Hcy levels and to explore the relationship between the changes in Hcy levels and the therapeutic outcome, which, to our best knowledge have not been investigated. Fifty-six first-episode and drug-naïve inpatients with schizophrenia were assigned to a 12-week treatment regime with risperidone...
April 15, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28418116/-what-is-the-point-of-life-an-interpretative-phenomenological-analysis-of-suicide-in-young-menwith-first-episode-psychosis
#11
Ruchika Gajwani, Michael Larkin, Chris Jackson
BACKGROUND: Lifetime risk of suicide in first-episode psychosis far exceeds the general population, with the risk of suicide persisting long after first presentation. There is strong evidence to suggest that women more frequently attempt suicide, while men are at a greater risk of completing suicide. First-hand experiential evidence is needed in order to better understand men's motives for, and struggles with, suicidality in early psychosis. METHODS: Semi-structured interviews were conducted with 7 participants...
April 18, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28415873/structural-brain-changes-in-schizophrenia-at-different-stages-of-the-illness-a-selective-review-of-longitudinal-magnetic-resonance-imaging-studies
#12
Bruno Dietsche, Tilo Kircher, Irina Falkenberg
OBJECTIVE: Schizophrenia is a devastating mental disorder accompanied by aberrant structural brain connectivity. The question whether schizophrenia is a progressive brain disorder is yet to be resolved. Thus, it is not clear when these structural alterations occur and how they develop over time. METHODS: In our selective review, we summarized recent findings from longitudinal magnetic resonance imaging studies investigating structural brain alterations and its impact on clinical outcome at different stages of the illness: (1) subjects at ultra-high risk of developing psychosis, (2) patients with a first episode psychosis, and (3) chronically ill patients...
May 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28412088/tobacco-smoking-and-its-association-with-cognition-in-first-episode-psychosis-patients
#13
Lauren M Hickling, Rocio Perez-Iglesias, Victor Ortiz-García de la Foz, Vincent Balanzá-Martínez, Philip McGuire, Benedicto Crespo-Facorro, Rosa Ayesa-Arriola
Available evidence suggests that nicotine may enhance cognitive functioning. Moreover, it has been suggested that the high prevalence of smoking in people with schizophrenia is in part due to self-medication behaviour to alleviate cognitive deficits. We assessed the association between tobacco smoking and cognitive functioning in a large population of first episode psychosis (FEP) patients (n=304) and healthy controls (n=156). Smokers were not tobacco deprived, or were minimally deprived (≤2h). Verbal memory, visual memory, working memory, processing speed, executive function, motor dexterity and attention were assessed...
April 12, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28406840/association-between-vitamin-d-status-and-schizophrenia-a-first-psychotic-episode-study
#14
José Salavert, Dolors Grados, Nuria Ramiro, Maria Isabel Carrión, Christian Fadeuilhe, Felipe Palma, Laura López, Alba Erra, Nicolás Ramírez
Vitamin D deficiency has been linked with schizophrenia. We aimed to determine whether patients with a first episode of psychosis (FEP) had lower vitamin D levels compared with controls considering their final diagnosis. We conducted a cross-sectional study determining 25-hydroxyvitamin D blood levels. 25-Hydroxyvitamin D levels were considered optimum at 20 ng/mL or greater. A group of 45 adult patients with FEP and a group of 22 healthy controls matched for age were recruited. The patient group was subdivided in two final diagnosis groups (schizophrenia versus other psychoses) after a 6-month follow-up...
May 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28402046/social-cognition-and-the-course-of-social-functioning-in-first-episode-psychosis
#15
Cindy B Woolverton, Emily K Bell, Aubrey M Moe, Patricia Harrison-Monroe, Nicholas J K Breitborde
BACKGROUND: Social functioning deficits greatly affect individuals with psychotic disorders resulting in decreased ability to maintain relationships, jobs and pursuit of educational goals. Deficits in social cognition have been hypothesized to be an important contributor to these deficits in social functioning. In particular, 5 domains of social cognition have been suggested to be relevant in the study of psychotic disorders: (1) attributional style, (2) emotion recognition, (3) social knowledge, (4) social perception and (5) theory of mind...
April 12, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28401151/white-matter-integrity-in-genetic-high-risk-individuals-and-first-episode-schizophrenia-patients-similarities-and-disassociations
#16
Yifang Zhou, Jie Liu, Naomi Driesen, Fay Womer, Kaiyuan Chen, Ye Wang, Xiaowei Jiang, Qian Zhou, Chuan Bai, Dahai Wang, Yanqing Tang, Fei Wang
White matter (WM) neuroimaging studies have shown varied findings at different stages of schizophrenia (SZ). Understanding these variations may elucidate distinct markers of genetic vulnerability and conversion to psychosis. To examine the similarities and differences in WM connectivity between those at-risk for and in early stages of SZ, a cross-sectional diffusion tensor imaging study of 48 individuals diagnosed with first-episode SZ (FE-SZ), 37 nonpsychotic individuals at a high genetic risk of SZ (GHR-SZ), and 67 healthy controls (HC) was conducted...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28398985/effectiveness-of-family-interventions-on-psychological-distress-and-expressed-emotion-in-family-members-of-individuals-diagnosed-with-first-episode-psychosis-a-systematic-review
#17
Wilai Napa, Patraporn Tungpunkom, Nisakorn Pothimas
BACKGROUND: A critical period for persons with first-episode psychosis is the first two years after diagnosis, when they are at high risk of suicide attempts, violent behaviors and substance abuse. This period also has a great impact on the psychological distress of family members, particularly caregivers who either provide care or live with ill family members. In addition, the families also report feelings of being overwhelmed when accessing service facilities at this critical point...
April 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28398566/twelve-month-health-care-use-and-mortality-in-commercially-insured-young-people-with-incident-psychosis-in-the-united-states
#18
Michael Schoenbaum, Jason M Sutherland, Andre Chappel, Susan Azrin, Amy B Goldstein, Agnes Rupp, Robert K Heinssen
OBJECTIVE: To assess 12-month mortality and patterns of outpatient and inpatient treatment among young people experiencing an incident episode of psychosis in the United States. METHOD: Prospective observational analysis of a population-based cohort of commercially insured individuals aged 16-30 receiving a first observed (index) diagnosis of psychosis in 2008-2009. Data come from the US Department of Health and Human Services' Multi-Payer Claims Database Pilot...
April 7, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28395674/antipsychotic-treatment-resistance-in-first-episode-psychosis-prevalence-subtypes-and-predictors
#19
A Demjaha, J M Lappin, D Stahl, M X Patel, J H MacCabe, O D Howes, M Heslin, U A Reininghaus, K Donoghue, B Lomas, M Charalambides, A Onyejiaka, P Fearon, P Jones, G Doody, C Morgan, P Dazzan, R M Murray
BACKGROUND: We examined longitudinally the course and predictors of treatment resistance in a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic treatment. We hypothesized that antipsychotic treatment resistance is: (a) present at illness onset; and (b) differentially associated with clinical and demographic factors. METHOD: The study sample comprised 323 FEP patients who were studied at first contact and at 10-year follow-up...
April 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28395229/depressive-symptoms-and-suicidal-behavior-after-first-episode-psychosis-a-comprehensive-systematic-review
#20
REVIEW
Ricardo Coentre, Miguel Cotrim Talina, Carlos Góis, Maria Luísa Figueira
Depressive symptoms and suicidal behavior are common among patients that suffered a first-episode psychosis. We searched Web of Knowledge(SM) and Pubmed® for English and Portuguese original articles investigating prevalence of depressive symptoms and/or suicidal behavior and associated factors after first-episode psychosis. We included 19 studies from 12 countries, 7 studied depressive symptoms and 12 suicidal behavior. The findings confirm that depressive symptoms and suicidal behavior have high rates in the years after first-episode psychosis...
April 5, 2017: Psychiatry Research
keyword
keyword
15768
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"