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Psychogenic Seizures

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https://www.readbyqxmd.com/read/28092837/differential-diagnosis-of-a-paroxysmal-neurological-event-do-neurologists-know-how-to-clinically-recognize-it
#1
Aleksandar J Ristić, Ksenija Mijović, Zoran Bukumirić, Nikola Vojvodić, Slavko Janković, Vladimir Baščarević, Tijana Đukić, Dragoslav Sokić
PURPOSE: To investigate ability to recognize paroxysmal neurological events (PNE) based on video-recorded events alone in a group of physicians treating prevalent neurological conditions. METHODS: Total of 12 patients' videos (6 epileptic seizures (ES), 4 psychogenic nonepileptic seizures (PNES), 2 other nonepileptic seizures (oNES)) were selected. Videos were displayed once to physicians blind to clinical data and final diagnosis. Physicians determined their clinical choice: ES, PNES, oNES, and I don't know (IDK)...
January 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28074997/-classification-of-idiopathic-generalised-epilepsies-in-patients-over-16-years-of-age
#2
J Sala-Padro, M Toledo, E Santamarina, M Gonzalez-Cuevas, M Raspall-Chaure, M Sueiras-Gil, M Quintana, J Salas-Puig
INTRODUCTION: Idiopathic generalised epilepsies (IGE) are a set of electroclinical syndromes with different phenotypes. Our aim is to analyse those phenotypes in patients over 16 years of age. PATIENTS AND METHODS: We conducted a retrospective analysis of a series of patients with IGE. They were classified as childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), epilepsy with tonic-clonic seizures only (TCSE), epilepsy with eyelid myoclonias and absences (EMA) and pure photogenic epilepsy (PE)...
January 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28065191/dissociation-in-patients-with-dissociative-seizures-relationships-with-trauma-and-seizure-symptoms
#3
S Pick, J D C Mellers, L H Goldstein
BACKGROUND: This study aimed to extend the current understanding of dissociative symptoms experienced by patients with dissociative (psychogenic, non-epileptic) seizures (DS), including psychological and somatoform types of symptomatology. An additional aim was to assess possible relationships between dissociation, traumatic experiences, post-traumatic symptoms and seizure manifestations in this group. METHOD: A total of 40 patients with DS were compared with a healthy control group (n = 43), matched on relevant demographic characteristics...
January 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28063373/psychological-interventions-for-psychogenic-non-epileptic-seizures-a-meta-analysis
#4
Perri Carlson, Kathryn Nicholson Perry
PURPOSE: The aim of this meta-analysis is to evaluate and synthesize the available evidence from the previous 20 years regarding the utility of psychological interventions in the management of psychogenic non-epileptic seizures (PNES). METHOD: Studies were retrieved from MEDLINE via OvidSP and PsychINFO. Selection criteria included controlled and before-after non-controlled studies including case series, using seizure frequency as an outcome measurement. Studies were required to assess one or more types of psychological intervention for the treatment of PNES in adults...
December 21, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28039841/how-reliable-is-ictal-duration-to-differentiate-psychogenic-nonepileptic-seizures-from-epileptic-seizures
#5
Udaya Seneviratne, Erica Minato, Eldho Paul
We sought to investigate (1) differences in ictal duration between psychogenic nonepileptic seizures (PNES) and epileptic seizures (ES), (2) the odds of being PNES when seizures last ≥5min, and (3) the value of ictal duration as a diagnostic test to differentiate PNES from ES. We retrospectively reviewed video-EEG recordings and tabulated ictal durations of all PNES and ES. We estimated the mean ictal durations of PNES and ES using linear mixed models. The odds of being PNES when seizures last ≥5min were estimated using logistic regression...
December 28, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28039840/attachment-style-relationship-quality-and-psychological-distress-in-patients-with-psychogenic-non-epileptic-seizures-versus-epilepsy
#6
Becky Green, Paul Norman, Markus Reuber
OBJECTIVES: Psychopathology levels are elevated in patients with psychogenic non-epileptic seizures (PNES) and those with epilepsy. However, patients with PNES report higher rates of trauma and neglect, poorer health-related quality of life (HRQoL), and an increased prevalence of insecure attachment. We examined to what extent attachment style and relationship quality with their main informal carer impact on levels of HRQoL, depression, and anxiety in patients with PNES versus those with epilepsy...
December 28, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28038392/prolonged-exposure-therapy-for-the-treatment-of-patients-diagnosed-with-psychogenic-non-epileptic-seizures-pnes-and-post-traumatic-stress-disorder-ptsd
#7
Lorna Myers, Urmi Vaidya-Mathur, Marcelo Lancman
OBJECTIVE: Although there is general consensus that psychogenic non-epileptic seizures (PNES) are treated with psychotherapy, the effectiveness of most psychotherapeutic modalities remains understudied. In this treatment series of 16 patients dually diagnosed with PNES and post-traumatic stress disorder (PTSD), we evaluated the effect of prolonged exposure therapy (PE) on reduction of PNES. Secondary measures included Beck Depression Inventory (BDI-II) and Post-Traumatic Disorder Diagnostic Scale (PDS)...
December 27, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28007363/an-emergency-medicine-focused-review-of-seizure-mimics
#8
James Webb, Brit Long, Alex Koyfman
BACKGROUND: Seizures result in a change in motor, sensory, and behavioral symptoms caused by abnormal neurologic electrical activity. The symptoms share similar presentations of several other conditions, leading to difficulties in diagnosis and frequent improper management. OBJECTIVE: This review evaluates adult patients with suspected seizure, signs and symptoms of seizure, mimics of seizure, and an approach to management of seizure mimics. DISCUSSION: A seizure is caused by abnormal neurologic electrical activity resulting in altered motor, sensory, and behavioral symptoms...
December 19, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27988107/understanding-psychogenic-nonepileptic-seizures-phenomenology-semiology-and-the-integrative-cognitive-model
#9
Markus Reuber, Richard J Brown
Psychogenic Nonepileptic Seizures (PNES) are one of the commonest differential diagnoses of epilepsy. This paper provides a narrative review of what has been learnt in the last 25 years regarding the visible manifestations, physiological features, subjective experiences and interactional aspects of PNES. We then explore how current insights into PNES semiology and phenomenology map onto the Integrative Cognitive Model (ICM), a new account of these phenomena that unifies previous approaches within a single explanatory framework...
November 15, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27984257/preliminary-predictors-of-initial-attendance-symptom-burden-and-motor-subtype-in-a-us-functional-neurological-disorders-clinic-population
#10
David L Perez, Sigrid S Young, Julie N King, Anthony J Guarino, Barbara A Dworetzky, Alice Flaherty, Zeina Chemali, David Caplan, Bradford C Dickerson
BACKGROUND AND OBJECTIVE: Although many patients present with functional neurological symptoms (FNS), few US clinics offer specialized FNS care, and data on clinic attendees remain limited. We determined predictors of initial attendance, symptom burden, and FNS subtype in the first patients referred to our Functional Neurological Disorders Clinic for suspected FNS. METHODS: We reviewed the charts of 62 consecutive patients (46 women, 16 men). Regression analyses investigated predictors of keeping the first scheduled clinic appointment...
December 2016: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
https://www.readbyqxmd.com/read/27965102/psychogenic-non-epileptic-seizures-the-daunting-mimicker
#11
EDITORIAL
I Osorio, M Markert
No abstract text is available yet for this article.
December 10, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27955838/risk-factors-for-diagnostic-delay-in-psychogenic-nonepileptic-seizures-among-children-and-adolescents
#12
Kette D Valente, Ruda Alessi, Silvia Vincentiis, Bernardo Dos Santos, Patricia Rzezak
BACKGROUND: This study aims to analyze a series of pediatric patients with psychogenic nonepileptic seizures (PNES) to establish the diagnostic gap and possible risk factors for the delayed diagnosis in this age group. METHODS: We evaluated all children with PNES documented by video electroencephalography. None had a previous diagnosis of PNES. In total, we included 53 children (interquartile range: 7 to 17 years; mean age 12.81 years [S.D. 3.15]; 60.4% girls) who underwent a protocol consisting of neurological and psychiatric interviews...
November 9, 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/27908324/-psychotherapeutic-treatment-of-psychogenic-non-epileptic-seizures
#13
Dröfn Hilmarsdóttir, Steffen Birk, Charlotte Ulrikka Rask
Psychogenic non-epileptic seizures (PNES) are seizures which clinically resemble epileptic seizures but are without concurrent abnormal electrical charges. Though PNES can be just as serious and disabling as epileptic seizures, specific treatment guidelines are lacking, and different types of treatments are used. In this article we address the current research on psychotherapeutic treatment for PNES by discussing recent reviews and six randomized controlled trials (RCTs) on the subject. In conclusion, larger well-designed RCTs are needed in order to support the evidence for psychological interventions for this patient group...
November 28, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27898362/psychogenic-non-epileptic-seizure-in-patients-with-intellectual-disability-with-special-focus-on-choice-of-therapeutic-intervention
#14
Kousuke Kanemoto, Hiroko Goji, Yukari Tadokoro, Etsushi Kato, Tomohiro Oshima
PURPOSE: There have been a number of studies exploring treatments for psychogenic non-epileptic seizure (PNES) but largely neglecting the sizable subgroup of patients with intellectual disability (ID). In the present study, we attempted to demonstrate effects and preferred modes of therapeutic intervention in PNES patients with ID being treated at a Japanese municipal center with a short referral chain. METHODS: We examined 46 PNES patients with ID (ID group) and 106 PNES patients without ID (non-ID group) retrospectively in case charts...
November 14, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27863319/aberrant-gamma-band-cortical-sources-and-functional-connectivity-in-adolescents-with-psychogenic-non-epileptic-seizures-a-preliminary-report
#15
Shreekantiah Umesh, Sai Krishna Tikka, Nishant Goyal, Vinod Kumar Sinha, Shamshul Haque Nizamie
Psychogenic non-epileptic seizures (PNES) resemble epileptic seizures, but lack clinically evident abnormal electrical activity in the brain. We aimed to assess resting gamma spectral power, current source distribution and functional connectivity in adolescents with PNES. Interictal, 32 channels electroencephalographic recording of 15 adolescents with PNES was compared with 10 matched healthy controls. Spectral power, current source distribution and lagged linear coherence were assessed. Statistically significant gamma spectral power, cortical sources and connectivity pattern was found in some brain areas...
January 2017: Psychiatry Research
https://www.readbyqxmd.com/read/27845151/data-fusion-for-paroxysmal-events-classification-from-eeg
#16
Evangelia Pippa, Evangelia I Zacharaki, Michael Koutroumanidis, Vasileios Megalooikonomou
BACKGROUND: Spatiotemporal analysis of electroencephalography is commonly used for classification of events since it allows capturing dependencies across channels. The significant increase of feature vector dimensionality however introduce noise and thus it does not allow the classification models to be trained using a limited number of samples usually available in clinical studies. NEW METHOD: Thus, we investigate the classification of epileptic and non-epileptic events based on temporal and spectral analysis through the application of three different fusion schemes for the combination of information across channels...
January 1, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27818795/juvenile-myoclonic-epilepsy-in-rural-western-india-not-yet-a-benign-syndrome
#17
Devangi Desai, Soaham Desai, Trilok Jani
Purpose. To study prevalence of uncontrolled seizures in patients with juvenile myoclonic epilepsy [JME] and assess factors responsible for it. Methods. An ambispective study of all patients with JME attending our epilepsy clinic was done. We recruited all patients with JME evaluated between 1 January 2009 and 31 December 2013 and followed them up to 31 December 2015. Results. Amongst 876 patients with epilepsy, JME was present in 73 patients. Amongst them, 53 [72.6%] had uncontrolled seizures prior to neurology consultation...
2016: Epilepsy Research and Treatment
https://www.readbyqxmd.com/read/27818368/psychogenic-non-epileptic-seizures
#18
Robert C Doss, W Curt LaFrance
Psychogenic non-epileptic seizures (PNES) are diagnosed in at least 10-40% of the patients seen for long-term monitoring of epilepsy, and it is no surprise that patients with PNES are often treated for epilepsy. Given the substantial economic costs and mental health burden of misdiagnosis, it is imperative to establish early identification, correct diagnosis, and effective treatment of PNES in order to provide the greatest opportunity for remission of events, improved psychological functioning, and social-vocational outcome...
December 1, 2016: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/27776298/neurologists-can-identify-diagnostic-linguistic-features-during-routine-seizure-clinic-interactions-results-of-a-one-day-teaching-intervention
#19
Laura Jenkins, Jeremy Cosgrove, Paul Chappell, Ammar Kheder, Dilraj Sokhi, Markus Reuber
The diagnostic distinction between epilepsy and psychogenic nonepileptic seizures (PNES) can be challenging. Previous studies have demonstrated that experts in conversation analysis can identify linguistic and interactional features in transcripts and recordings of interviews with patients that reliably distinguish between epilepsy and PNES. In this study, ten senior neurology trainees took part in a one-day intervention workshop about linguistic and interactional differences in the conversation behavior of patients with epilepsy and those with PNES...
October 21, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27768938/hyperammonaemia-and-associated-factors-in-unprovoked-convulsive-seizures-a-cross-sectional-study
#20
Kenichiro Sato, Noritoshi Arai, Aki Omori, Ayumi Hida, Akio Kimura, Sousuke Takeuchi
PURPOSE: Hyperammonaemia is frequently observed in patients who have experienced convulsive seizures. Although excessive muscle contraction is presumed to be responsible for the elevated levels of ammonia, the underlying mechanism is poorly understood. The present study aimed to identify the independent factors associated with ammonia elevation using large-scale multivariate analysis. METHODS: We conducted a cross-sectional study involving 379 adult patients who had been transported to our emergency department and treated for unprovoked convulsive seizures between August 2010 and September 2015...
December 2016: Seizure: the Journal of the British Epilepsy Association
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