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Appropriate use criteria

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https://www.readbyqxmd.com/read/28320168/a-systematic-comparison-of-key-features-of-ischemic-stroke-prevention-guidelines-in-low-and-middle-income-vs-high-income-countries
#1
REVIEW
Hernán Bayona, Mayowa Owolabi, Wuwei Feng, Paul Olowoyo, Joseph Yaria, Rufus Akinyemi, James R Sawers, Bruce Ovbiagele
BACKGROUND AND PURPOSE: Implementation of contextually appropriate, evidence-based, expert-recommended stroke prevention guideline is particularly important in Low-Income Countries (LMICs), which bear disproportional larger burden of stroke while possessing fewer resources. However, key quality characteristics of guidelines issued in LMICs compared with those in High-Income Countries (HICs) have not been systematically studied. We aimed to compare important features of stroke prevention guidelines issued in these groups...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28319799/occurrence-of-hepatitis-a-and-e-and-norovirus-gi-and-gii-in-ready-to-eat-vegetables-in-italy
#2
V Terio, M Bottaro, E Pavoni, M N Losio, A Serraino, F Giacometti, V Martella, A Mottola, A Di Pinto, G Tantillo
Fresh vegetables and their ready-to-eat (RTE) salads have become increasingly recognized as potential vehicles for foodborne diseases. The EU Reg. 1441/2007 establishes microbiological criteria for bacterial pathogens for products placed on the market during their shelf-life (i.e. Salmonella spp., Listeria monocytogenes) for pre-cut fruits and vegetables (RTE) whilst it does not address the problem of contamination by enteric viruses. In this study we investigated the contamination by hepatitis A virus (HAV), hepatitis E virus (HEV) and norovirus (NoV) in 911 ready-to-eat vegetable samples taken from products at retail in Apulia and in Lombardia...
March 14, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28317643/biomarkers-for-the-diagnosis-of-alzheimer-s-disease-in-clinical-practice-an-italian-intersocietal-roadmap
#3
Giovanni B Frisoni, Daniela Perani, Stefano Bastianello, Gaetano Bernardi, Corinna Porteri, Marina Boccardi, Stefano F Cappa, Marco Trabucchi, Alessandro Padovani
Biomarkers of brain amyloidosis and neurodegeneration/synaptic dysfunction are featured in recent diagnostic criteria for Alzheimer's disease. Several gaps in our knowledge, however, need to be filled before they can be adopted clinically. The aim of this article is to describe a roadmap, developed by a multidisciplinary task force, to rationally implement biomarkers for Italian Memory Clinics. This roadmap is based on a framework comprising 5 sequential phases: identification of leads for potentially useful biomarkers; development of clinical assays for clinical disease; evaluation of detection of early stages; definition of operating characteristics in relevant populations; and estimation of reducing disease-associated mortality, morbidity, and disability...
April 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28316939/application-of-established-pathophysiologic-processes-brings-greater-clarity-to-diagnosis-and-treatment-of-hyponatremia
#4
EDITORIAL
John K Maesaka, Louis J Imbriano, Nobuyuki Miyawaki
Hyponatremia, serum sodium < 135 mEq/L, is the most common electrolyte abnormality and is in a state of flux. Hyponatremic patients are symptomatic and should be treated but our inability to consistently determine the causes of hyponatremia has hampered the delivery of appropriate therapy. This is especially applicable to differentiating syndrome of inappropriate antidiuresis (SIAD) from cerebral salt wasting (CSW) or more appropriately, renal salt wasting (RSW), because of divergent therapeutic goals, to water-restrict in SIAD and administer salt and water in RSW...
March 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28315206/otorhinolaryngological-toxicities-of-new-drugs-in-oncology
#5
REVIEW
Dana M Hartl, Daphné Morel, Erika Saavedra, Christophe Massard, Alessandra Rinaldo, Nabil F Saba, Alfio Ferlito, Jean-Charles Soria
Many new or relatively new cancer drugs-personalized anticancer agents-have been approved for use in various clinical settings in oncology or are still under evaluation in clinical trials. Targeted therapies as well as new immune checkpoint blockers have toxicity profiles that differ from conventional cytotoxic chemotherapy, and many can cause adverse effects that affect the mouth and pharynx, the nasal cavities, and the larynx. This review aims to provide an overview of current knowledge concerning these side effects and contemporary management...
March 17, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28314898/economic-burden-of-osteoporosis-related-hip-fracture-in-asia-a-systematic-review
#6
REVIEW
N-A Mohd-Tahir, S-C Li
This review analyzes the economic costs of HF in Asia. The availability and quality of studies on the burden of osteoporosis in Asia are very scarce. There is a need to encourage more quality cost of osteoporosis studies based on standardized methods to convince healthcare authorities in implementing appropriate strategies. INTRODUCTION: Osteoporosis fractures, especially hip fractures, impose large economic costs to governments and societies. This review aimed to systematically analyze available evidence on healthcare costs associated with osteoporosis-related hip fractures (HF) in Asia...
March 17, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28314153/sewage-sludge-disposal-strategies-for-sustainable-development
#7
Małgorzata Kacprzak, Ewa Neczaj, Krzysztof Fijałkowski, Anna Grobelak, Anna Grosser, Małgorzata Worwag, Agnieszka Rorat, Helge Brattebo, Åsgeir Almås, Bal Ram Singh
The main objective of the present review is to compare the existing sewage sludge management solutions in terms of their environmental sustainability. The most commonly used strategies, that include treatment and disposal has been favored within the present state-of-art, considering existing legislation (at European and national level), characterization, ecotoxicology, waste management and actual routs used currently in particular European countries. Selected decision making tools, namely End-of-waste criteria and Life Cycle Assessment has been proposed in order to appropriately assess the possible environmental, economic and technical evaluation of different systems...
March 14, 2017: Environmental Research
https://www.readbyqxmd.com/read/28301666/adaptation-of-the-keratinosens%C3%A2-skin-sensitisation-test-to-animal-product-free-cell-culture
#8
Nathalie Belot, Bushra Sim, Christopher Longmore Longmore, Lottie Roscoe, Carol Treasure
Skin sensitisation is the process by which a substance leads to an allergic reaction following skin contact. The process has been described as an adverse outcome pathway (AOP), including several key events, from skin penetration and covalent protein binding, to keratinocyte activation, dendritic cell activation and T-lymphocyte proliferation. The in vitro assay KeratinoSens™ measures the activation of keratinocytes. It is fully accepted at a regulatory level (OECD TG 442d) and appropriate for compliance with a range of legislation including the EU Cosmetics Regulation, REACH, and the CLP Regulation...
March 16, 2017: ALTEX
https://www.readbyqxmd.com/read/28301316/a-new-approach-to-define-acceptance-limits-for-hematology-in-external-quality-assessment-schemes
#9
Mohamed Rida Soumali, Marjan Van Blerk, Abdelhadi Akharif, Stéphanie Albarède, Dagmar Kesseler, Gabriela Gutierrez, Barbara de la Salle, Inger Plum, Anne Guyard, Ana Paula Favia, Wim Coucke
BACKGROUND: A study performed in 2007 comparing the evaluation procedures used in European external quality assessment schemes (EQAS) for hemoglobin and leukocyte concentrations showed that acceptance criteria vary widely. For this reason, the Hematology working group from the European Organisation for External Quality Assurance Providers in Laboratory Medicine (EQALM) decided to perform a statistical study with the aim of establishing appropriate acceptance limits (AL) allowing harmonization between the evaluation procedures of European EQAS organizers...
March 16, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28299300/the-health-seeking-behaviors-and-perceptions-of-iranian-patient-with-osteoarthritis-about-pain-management-a-qualitative-study
#10
Vahid Zamanzadeh, Fazlollah Ahmadi, Marjaneh Foolady, Mozhgan Behshid, Alireza Irajpoor
Introduction: Pain is the main reason for patients with osteoarthritis (OA) to visit health clinics. Health seeking behaviors indicate unmet patient needs and lack of understanding of OA pain patterns. This study aimed to describe the experiences of Iranian patients with OA and explore their health seeking behaviors and perceptions on pain management related to osteoarthritis. Methods: Using a qualitative approach, data was collected by interviewing 19 patients, 2 family members, and 5 health care providers from the in-patient and out-patient clinics, and physicians' offices...
March 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/28298198/maternal-and-neonatal-service-usage-and-determinants-in-fragile-and-conflict-affected-situations-a-systematic-review-of-asia-and-the-middle-east
#11
Saji S Gopalan, Ashis Das, Natasha Howard
BACKGROUND: Fragile and conflict-affected situations (FCS) in Asia and the Middle-East contribute significantly to global maternal and neonatal deaths. This systematic review explored maternal and neonatal health (MNH) services usage and determinants in FCS in Asia and the Middle-East to inform policy on health service provision in these challenging settings. METHODS: This systematic review was conducted using a standardised protocol. Pubmed, Embase, Web of Science, and selected development agency websites were searched for studies meeting inclusion criteria...
March 15, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28296923/screening-gestational-diabetes-mellitus-the-role-of-maternal-age
#12
Chun-Heng Kuo, Szu-Chi Chen, Chi-Tai Fang, Feng-Jung Nien, En-Tzu Wu, Shin-Yu Lin, Lee-Ming Chuang, Chien-Nan Lee, Hung-Yuan Li
OBJECTIVE: Using a specific cutoff of fasting plasma glucose (FPG) to screen gestational diabetes mellitus (GDM) can reduce the use of oral glucose tolerance tests (OGTT). Since the prevalence of GDM increases with age, this screening method may not be appropriate in healthcare systems where women become pregnant at older ages. Therefore, we aimed to develop a screening algorithm for GDM that takes maternal age into consideration. METHODS: We included 945 pregnant women without history of GDM who received 75g OGTT to diagnose GDM in 2011...
2017: PloS One
https://www.readbyqxmd.com/read/28296695/appropriate-use-criteria-in-adult-scoliosis
#13
Sigurd H Berven
No abstract text is available yet for this article.
April 1, 2017: Spine
https://www.readbyqxmd.com/read/28296671/the-use-of-thrombolytic-therapy-in-the-treatment-of-frostbite-injury
#14
Allyson Wexler, Sarah Zavala
Frostbite can lead to severe consequences including loss of digits and limbs. One of the mechanisms of frostbite includes vascular thrombosis. The use of tissue plasminogen activator (tPA) in frostbite has been shown to be effective in case reports and small prospective studies. A retrospective chart review was performed on all patients admitted for frostbite between January 2008 and April 2015, and six patients were identified as having received treatment with intravenous tPA. Patients received an initial bolus dose followed by a 6-hour infusion of tPA...
March 3, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28296651/the-predictive-validity-of-a-text-based-situational-judgment-test-in-undergraduate-medical-and-dental-school-admissions
#15
Fiona Patterson, Fran Cousans, Helena Edwards, Anna Rosselli, Sandra Nicholson, Barry Wright
PROBLEM: Situational judgment tests (SJTs) can be used to assess the nonacademic attributes necessary for medical and dental trainees to become successful practitioners. Evidence for SJTs' predictive validity, however, relates predominantly to selection in postgraduate settings or using video-based SJTs at the undergraduate level; it may not be directly transferable to text-based SJTs in undergraduate medical and dental school selection. This preliminary study aimed to address these gaps by assessing the validity of the UK Clinical Aptitude Test (UKCAT) text-based SJT...
March 14, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28296526/speech-perception-in-mandarin-speaking-children-with-cochlear-implants-a-systematic-review
#16
Yuan Chen, Lena L N Wong
OBJECTIVE: This paper reviewed the literature on the trajectories and the factors significantly affecting post-implantation speech perception development in Mandarin-speaking children with cochlear implants (CIs). DESIGN: A systematic literature search of textbooks and peer-reviewed published journal articles in online bibliographic databases was conducted. STUDY SAMPLE: PubMed, Scopus and Wiley online library were searched for eligible studies based on predefined inclusion and exclusion criteria...
March 15, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28296513/who-is-the-preferred-tutor-in-clinical-skills-training-physicians-nurses-or-peers
#17
Ece Şükriye Abay, Sevgi Turan, Orhan Odabaşı, Melih Elçin
Phenomenon: Clinical skills centers allow structured training of undergraduate medical students for the acquisition of clinical skills in a simulated environment. Physician, nurse, or peer tutors are employed for training in those centers. All tutors should have appropriate training about the methodology used in the clinical skills training. Many of the studies revealed the effectiveness of various types of tutors. The aim of our study was to evaluate medical students' satisfaction with clinical skills training, and their opinions about the differences in coaching skills among the physician, nurse, and peer tutors...
March 15, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28294593/effect-of-vitamin-d-replacement-in-primary-hyperparathyroidism-with-concurrent-vitamin-d-deficiency-a-systematic-review-and-meta-analysis
#18
Huai Heng Loh, Lee Ling Lim, Anne Yee, Huai Seng Loh, Shireene R Vethakkan
INTRODUCTION: We conducted a meta-analysis to assess the effects of vitamin D replacement on biochemical and skeletal parameters in subjects with mild primary hyperparathyroidism (PHPT) and coexistent vitamin D deficiency. EVIDENCE ACQUISITION: A systematic search of all English-language medical literature published from 1980 till May 2016 using Pubmed, Embase and Ovid was performed. Nine observational studies were evaluated after fulfilling the inclusion and exclusion criteria...
March 14, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28293906/who-should-be-considered-for-islet-transplantation-alone
#19
REVIEW
Nantia Othonos, Pratik Choudhary
PURPOSE OF REVIEW: Episodic hypoglycemia is an almost inevitable consequence of exogenous insulin treatment of type 1 diabetes, and in up to 30% of patients, this can lead to impaired awareness of hypoglycemia. This predisposes to recurrent severe hypoglycemia and has a huge impact on quality of life. Although many patients can get resolution of severe hypoglycemia through novel education and technology, some patients continue to have ongoing life-threatening hypoglycemia. Islet transplantation offers an alternative therapeutic option for these patients, in whom these conventional approaches have been unsuccessful...
April 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28293559/data-driven-risk-assessment-from-small-scale-epidemics-estimation-and-model-choice-for-spatio-temporal-data-with-application-to-a-classical-swine-fever-outbreak
#20
Kokouvi Gamado, Glenn Marion, Thibaud Porphyre
Livestock epidemics have the potential to give rise to significant economic, welfare, and social costs. Incursions of emerging and re-emerging pathogens may lead to small and repeated outbreaks. Analysis of the resulting data is statistically challenging but can inform disease preparedness reducing potential future losses. We present a framework for spatial risk assessment of disease incursions based on data from small localized historic outbreaks. We focus on between-farm spread of livestock pathogens and illustrate our methods by application to data on the small outbreak of Classical Swine Fever (CSF) that occurred in 2000 in East Anglia, UK...
2017: Frontiers in Veterinary Science
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