Peter K Yang, Sandra L Jackson, Brian R Charest, Yiling J Cheng, Yan V Sun, Sridharan Raghavan, Elizabeth M Litkowski, Brian T Legvold, Mary K Rhee, Richard A Oram, Elena V Kuklina, Marijana Vujkovic, Peter D Reaven, Kelly Cho, Aaron Leong, Peter W F Wilson, Jin Zhou, Donald R Miller, Seth A Sharp, Lisa R Staimez, Kari E North, Heather M Highland, Lawrence S Phillips
OBJECTIVE: To characterize high type 1 diabetes (T1D) genetic risk in a population where type 2 diabetes (T2D) predominates. RESEARCH DESIGN AND METHODS: Characteristics typically associated with T1D were assessed in 109,594 Million Veteran Program participants with adult-onset diabetes, 2011-2021, who had T1D genetic risk scores (GRS) defined as low (0 to <45%), medium (45 to <90%), high (90 to <95%), or highest (≥95%). RESULTS: T1D characteristics increased progressively with higher genetic risk (P < 0...
April 12, 2024: Diabetes Care