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https://www.readbyqxmd.com/read/28327093/continuous-non-invasive-finger-cuff-caretaker%C3%A2-comparable-to-invasive-intra-arterial-pressure-in-patients-undergoing-major-intra-abdominal-surgery
#1
Irwin Gratz, Edward Deal, Francis Spitz, Martin Baruch, I Elaine Allen, Julia E Seaman, Erin Pukenas, Smith Jean
BACKGROUND: Despite increased interest in non-invasive arterial pressure monitoring, the majority of commercially available technologies have failed to satisfy the limits established for the validation of automatic arterial pressure monitoring by the Association for the Advancement of Medical Instrumentation (AAMI). According to the ANSI/AAMI/ISO 81060-2:2013 standards, the group-average accuracy and precision are defined as acceptable if bias is not greater than 5 mmHg and standard deviation is not greater than 8 mmHg...
March 21, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28295678/founder-representation-and-effective-population-size-in-old-versus-young-breeds-genetic-diversity-of-finnish-and-nordic-spitz
#2
M Kumpulainen, H Anderson, T Svevar, I Kangasvuo, J Donner, J Pohjoismäki
Finnish Spitz is 130-year-old breed and has been highly popular in Finland throughout its history. Nordic Spitz is very similar to Finnish Spitz by origin and use, but is a relatively recent breed with much smaller population size. To see how breed age and breeding history have influenced the current population, we performed comprehensive population genetic analysis using pedigree data of 28,119 Finnish and 9,009 Nordic Spitzes combined with genomewide single nucleotide polymorphism (SNP) data from 135 Finnish and 110 Nordic Spitzes...
March 10, 2017: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/28295655/characteristics-of-spitz-nevi-atypical-spitz-nevi-and-melanomas-in-patients-younger-than-20-years
#3
Efthymia Soura, Michaela Plaka, Christina Stefanaki, Vassiliki Chasapi, Erietta Christofidou, Christina Antoniou, Alexander Stratigos
The Spectrum of Spitzoid tumors and early onset melanomas has been extensively studied during the last few years.(1, 2) Although significant progress has been made in the histopathological and clinical description of these lesions, the biologic potential of the most atypical lesions of the spectrum still remains to be elucidated. This article is protected by copyright. All rights reserved.
March 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28291964/application-of-a-parallelizable-perfusion-bioreactor-for-physiologic-3d-cell-culture
#4
Dominik Egger, Sarah Spitz, Monica Fischer, Stephan Handschuh, Martin Glösmann, Benedikt Friemert, Monika Egerbacher, Cornelia Kasper
It is crucial but challenging to keep physiologic conditions during the cultivation of 3D cell scaffold constructs for the optimization of 3D cell culture processes. Therefore, we demonstrate the benefits of a recently developed miniaturized perfusion bioreactor together with a specialized incubator system that allows for the cultivation of multiple samples while screening different conditions. Hence, a decellularized bone matrix was tested towards its suitability for 3D osteogenic differentiation under flow perfusion conditions...
March 15, 2017: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/28290622/melanoma-and-melanocytic-nevi-in-paediatric-patients-a-single-institution-experience
#5
Paola Sgubbi, Francesco Savoia, Emi Dika, Iria Neri, Pier A Fanti, Annalisa Patrizi
BACKGROUND: Melanoma is an infrequent neoplasm in children and adolescents. The number of consultancies for melanocytic nevi control in the paediatric population is increased by the major anxiety of parents and paediatricians. METHODS: A retrospective chart review was performed in order to evaluate the incidence rate of melanoma, Spitz nevi, congenital and acquired melanocytic nevi in patients aged 14 years or less and referred to our institution from April 2010 to September 2015...
March 14, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28239519/white-matter-integrity-of-the-medial-forebrain-bundle-and-attention-and-working-memory-deficits-following-traumatic-brain-injury
#6
Jacqueline A Owens, Gershon Spitz, Jennie L Ponsford, Alicia R Dymowski, Nicholas Ferris, Catherine Willmott
BACKGROUND AND OBJECTIVE: The medial forebrain bundle (MFB) contains ascending catecholamine fibers that project to the prefrontal cortex (PFC). Damage to these fibers following traumatic brain injury (TBI) may alter extracellular catecholamine levels in the PFC and impede attention and working memory ability. This study investigated white matter microstructure of the medial MFB, specifically the supero-lateral branch (slMFB), following TBI, and its association with performance on attention and working memory tasks...
February 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28235826/a-new-reference-genome-assembly-for-the-microcrustacean-daphnia-pulex
#7
Zhiqiang Ye, Sen Xu, Ken Spitze, Jana Asselman, Xiaoqian Jiang, Matthew S Ackerman, Jacqueline Lopez, Brent Harker, R Taylor Raborn, W Kelley Thomas, Jordan Ramsdell, Michael E Pfrender, Michael Lynch
Comparing genomes of closely related genotypes from populations with distinct demographic histories can help reveal the impact of effective population size on genome evolution. For this purpose, we present a high-quality genome assembly of Daphnia pulex (PA42), and compare this with the first sequenced genome of this species (TCO), which was derived from an isolate from a population with >90% reduction in nucleotide diversity. PA42 has numerous similarities to TCO at the gene level, with an average amino-acid sequence identity of 98...
February 24, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28204935/a-review-of-body-dysmorphic-disorder-in-aesthetic-surgery-patients-and-the-legal-implications
#8
Iliana E Sweis, Jamie Spitz, David R Barry, Mimis Cohen
BACKGROUND: Body dysmorphic disorder (BDD) is an often under-recognized yet severe psychiatric illness. There is limited guidance for plastic surgeons in the USA in how to recognize and manage patients with BDD and protect themselves from potential litigation and harm. Therefore, in collaboration with legal counsel, we remind our profession of the serious nature of patients with BDD, provide warning signs for recognizing BDD, and critically evaluate the validity of informed consent and the legal ramifications of operating on such patients in the USA...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28186096/spitz-nevi-and-spitzoid-melanomas-exome-sequencing-and-comparison-with-conventional-melanocytic-nevi-and-melanomas
#9
Rossitza Lazova, Natapol Pornputtapong, Ruth Halaban, Marcus Bosenberg, Yalai Bai, Hao Chai, Michael Krauthammer
We performed exome sequencing of 77 melanocytic specimens composed of Spitz nevi (n=29), Spitzoid melanomas (n=27), and benign melanocytic nevi (n=21), and compared the results with published melanoma sequencing data. Our study highlights the prominent similarity between Spitzoid and conventional melanomas with similar copy number changes and high and equal numbers of ultraviolet-induced coding mutations affecting similar driver genes. Mutations in MEN1, PRKAR1A, and DNMT3A in Spitzoid melanomas may indicate involvement of the protein kinase A pathway, or a role of DNA methylation in the disease...
February 10, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28182282/antenatal-determinants-of-parental-attachment-and-parenting-alliance-how-do-mothers-and-fathers-differ
#10
Rita Luz, Astrid George, Rachel Vieux, Elisabeth Spitz
Parental (parent-to-infant) attachment and parenting alliance are defined as two important components of psychoaffective adjustment to the parental role. This study aimed to build a predictive model of parental attachment and parenting alliance for mothers and fathers using partial least squares-structural equation modeling. Specifically, we were interested in assessing how adult romantic attachment, marital quality, and psychological distress influenced parental attachment (parent-to-infant) and parenting alliance...
March 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28181035/complete-genome-sequence-of-a-hepatitis-b-virus-isolate-of-genotype-d2-subtype-adrq-from-brazil
#11
Natália Spitz, Aline S Moreira, Francisco C A Mello, Helena Cristina F Franz, Selma A Gomes, Natalia M Araujo
Hepatitis B virus (HBV) has been classified into 10 distinct serological subtypes of the surface antigen (HBsAg) that can be predicted by sequencing of the corresponding S gene. HBV genotype D usually displays determinants of subtypes ayw2 or ayw3. On the other hand, subtype adrq+ has been found exclusively in association with genotype C. Here, we describe the first HBV genome (isolate BR32) belonging to genotype D with the serological subtype adrq+. This isolate had a genome length of 3,062 nucleotides (nt), and no recombination events were observed in the BR32 genome that could explain the occurrence of the subtype adr in a genotype D isolate...
February 8, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28178045/assessment-of-transvaginal-ultrasound-cervical-length-image-quality
#12
Rupsa C Boelig, Helen Feltovich, Jean Lea Spitz, Gregory Toland, Vincenzo Berghella, Jay D Iams
OBJECTIVE: To use data from the Cervical Length Education and Review program to evaluate the quality of transvaginal cervical length ultrasonography by trained imagers (ie, ultrasonographers, radiologists, perinatologists). METHODS: This is a retrospective observational study of data from the Cervical Length Education and Review program. Candidates underwent an online lecture series, examination, and submitted a batch of images for review. For a candidate's batch of images to pass, all images must meet at least seven of the nine criteria assessed, the overall batch score needs to be 80% or greater, correct caliper placement must be met for all images, and the same criterion cannot be consistently missed...
March 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28135210/polypoid-spitz-nevus-with-a-halo-reaction
#13
Angel Fernandez-Flores, Marcela Saeb-Lima, José Luis Rodriguez-Peralto
Approximately, 2% of Spitz nevi are polypoid; between 3.6% and 7.4% present with a halo reaction. In tandem, these low percentages make the presence of a polypoid Spitz nevus with a halo reaction uncommon; we have not found reports of any previous cases. In the current report, we present a polypoid Spitz nevus with a halo reaction on the back of a 10-year-old male and discuss the morphologic findings. The lesion showed preserved nuclear expression of BAP1. There was no immunohistochemical expression of BRAF and ALK, while the melanocytic cells expressed p16...
February 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28129710/interventions-for-resuming-driving-after-traumatic-brain-injury
#14
Pamela E Ross, Marilyn Di Stefano, Judith Charlton, Gershon Spitz, Jennie L Ponsford
PURPOSE: To describe the goals, processes, resources and outcomes of on-road training lessons provided to drivers with traumatic brain injury (TBI) who failed an initial occupational therapy (OT) driver assessment. METHOD: Descriptive cohort study using file audit design of 340 drivers with mild to severe TBI. Measures included; number and goals of on-road training lessons and reassessments, time from injury to independent driving, license restrictions, years licensed, physical/visual impairments and injury severity...
January 27, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28118479/update-on-dermoscopy-of-spitz-reed-naevi-and-management-guidelines-by-the-international-dermoscopy-society
#15
REVIEW
A Lallas, Z Apalla, D Ioannides, E Lazaridou, A Kyrgidi, P Broganelli, R Alfano, I Zalaudek, G Argenziano
Spitzoid lesions represent a challenging and controversial group of tumours, in terms of clinical recognition, biologic behavior and management strategies. Although Spitz naevi are considered benign tumours, their clinical and dermoscopic morphologic overlap with spitzoid melanoma renders the management of spitzoid lesions particularly difficult. The controversy deepens because of the existence of tumours that cannot be safely histopathologically diagnosed as naevi or melanomas (atypical Spitz tumours). The dual objective of the present study was to provide an updated classification on dermoscopy of Spitz naevi, and management recommendations of spitzoid looking lesions based on a consensus among experts in the field...
January 24, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28102445/-congenital-nevus-atypical-spitz-nevus-or-spitzoid-melanoma
#16
A Blum, M Tanaka, K S Kraemer-Schultheiss, J Bauer
No abstract text is available yet for this article.
January 19, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28053996/zika-virus-causing-encephalomyelitis-associated-with-immunoactivation
#17
Rafael Mello Galliez, Mariana Spitz, Patricia Piazza Rafful, Marcelo Cagy, Claudia Escosteguy, Caroline Spósito Brito Germano, Elisa Sasse, Alessandro Luis Gonçalves, Paola Paz Silveira, Paula Pezzuto, Alice Maria de Magalhães Ornelas, Amilcar Tanuri, Renato Santana Aguiar, Fernanda Tovar Moll
Brazil has experienced a Zika virus (ZIKV) outbreak with increased incidence of congenital malformations and neurological manifestations. We describe a case of a 26-year-old Brazilian Caucasian man infected with ZIKV and diagnosed with encephalomyelitis. Brain and spinal cord images showed hyperintense lesions on T2 and fluid-attenuated inversion recovery (FLAIR), and levels of proinflammatory cytokines in the cerebrospinal fluid showed a remarkable increase of interleukin (IL)-6 and IL-8. The observed pattern suggests immune activation during the acute phase, along with the neurological impairment, with normalization in the recovery phase...
October 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28041810/the-year-in-cardiothoracic-and-vascular-anesthesia-selected-highlights-from-2016
#18
REVIEW
Harish Ramakrishna, Jacob T Gutsche, Prakash A Patel, Adam S Evans, Menachem Weiner, Steven T Morozowich, Emily K Gordon, Hynek Riha, Joseph Bracker, Kamrouz Ghadimi, Sunberri Murphy, Warren Spitz, Emily MacKay, Theodore J Cios, Anita K Malhotra, Elvera Baron, Shahzad Shaefi, Jens Fassl, Stuart J Weiss, George Silvay, John G T Augoustides
No abstract text is available yet for this article.
October 14, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28027177/the-visor-flap-a-novel-design-for-scalp-wound-closure
#19
Lisa Hwang, Ni-Ka Ford, Jamie Spitz, Marco Ellis
Full-thickness scalp defects pose a reconstructive problem in the setting of infection, radiation, and underlying calvarial defects. Current options include dermal matrices, skin grafts, and local fasciocutaneous flaps. Free tissue transfer is frequently required when scalp-based flaps fail or the wound is significantly large or complex. The authors present 7 patients of complex scalp defect reconstruction using the novel visor flap. The visor flap is a bipedicled advancement flap with a triangular posterior extension...
March 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28024363/hierarchical-metal-oxide-topographies-replicated-from-highly-textured-graphene-oxide-by-intercalation-templating
#20
Po-Yen Chen, Muchun Liu, Thomas M Valentin, Zhongying Wang, Ruben Spitz Steinberg, Jaskiranjeet Sodhi, Ian Y Wong, Robert H Hurt
Confined assembly in the intersheet gallery spaces of two-dimensional (2D) materials is an emerging templating route for creation of ultrathin material architectures. Here, we demonstrate a general synthetic route for transcribing complex wrinkled and crumpled topographies in graphene oxide (GO) films into textured metal oxides. Intercalation of hydrated metal ions into textured GO multilayer films followed by dehydration, thermal decomposition, and air oxidation produces Zn, Al, Mn, and Cu oxide films with high-fidelity replication of the original GO textures, including "multi-generational", multiscale textures that have been recently achieved through extreme graphene compression...
December 27, 2016: ACS Nano
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