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Margin fit

Spencer T Brinker, Steven P Kearney, Thomas J Royston, Dieter Klatt
The mechanical properties of tissue are sensitive to pathological changes, which is the basis for using dynamic elastography as a diagnostic tool. The purpose of this study is a concurrent cross-modality comparison of two dynamic elastography methods, Magnetic Resonance Elastography (MRE) and Scanning Laser Doppler Vibrometry (SLDV) using a single vibration source method. Cylindrical soft tissue mimicking specimens of Plastisol and Ecoflex are stimulated with 60, 100, 150, and 250 Hz sinusoidal vibration during imaging...
May 8, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Chiaw Ling Chng, Hong Chang Tan, Chow Wei Too, Wei Ying Lim, Priscilla Pei Sze Chiam, Ling Zhu, Nivedita Vikas Nadkarni, Adoree Yi Ying Lim
INTRODUCTION: We aimed to compare the malignancy risk stratification of histologically proven thyroid nodules using the 2015 American Thyroid Association (ATA) Management Guidelines, 2014 British Thyroid Association (BTA) Guidelines for the Management of Thyroid Cancer and Thyroid Imaging Reporting and Data System (TIRADS). METHODS: Thyroid nodules measuring > 1 cm resected over 5.5 years were retrospectively studied. Information like gender and age, and cytology and histopathology results were collected...
May 18, 2018: Singapore Medical Journal
Pauliina Moilanen, Jenni Hjerppe, Lippo Lassila, Timo Närhi
OBJECTIVES: To examine fracture strength and precision of fit of screw-retained anterior monolithic zirconia crowns made directly on implants or by cementing on prefabricated titanium bases, and to compare these to industrially produced Procera crowns. . MATERIALS AND METHODS: Monolithic screw-retained implant crowns were produced by CAD/CAM method (Zirkonzahn, Italy) using either partially (PSZ, Prettau, Zirconzahn, Italy) or fully stabilized (FSZ, Prettau Anterior, Zirkonzahn) zirconia...
May 15, 2018: Journal of Oral Implantology
Theresa Dicke, Herbert W Marsh, Philip Riley, Philip D Parker, Jiesi Guo, Marcus Horwood
School principals world-wide report high levels of strain and attrition resulting in a shortage of qualified principals. It is thus crucial to identify psychosocial risk factors that reflect principals' occupational wellbeing. For this purpose, we used the Copenhagen Psychosocial Questionnaire (COPSOQ-II), a widely used self-report measure covering multiple psychosocial factors identified by leading occupational stress theories. We evaluated the COPSOQ-II regarding factor structure and longitudinal, discriminant, and convergent validity using latent structural equation modeling in a large sample of Australian school principals ( N = 2,049)...
2018: Frontiers in Psychology
Kim N Du, Lei Feng, Abigail Newhouse, Jeel Mehta, Javier Lasala, Gabriel E Mena, Wayne L Hofstetter, Juan P Cata
BACKGROUND: Perioperative opioid use is associated with poor survival in patients with esophageal squamous cell carcinoma. The most common histological type of esophageal cancer in western countries is adenocarcinoma. The objective of this study was to evaluate the association between intraoperative opioid consumption and survival in patients with adenocarcinoma and squamous cell carcinoma of the esophagus. METHODS: Records of patients who had undergone esophageal cancer surgery between January 2000 and January 2017 were reviewed...
May 10, 2018: Anesthesia and Analgesia
Syed Rashid Habib, Asim Khaled Al Otaibi, Talal Ali Al Anazi, Samer Mosleh Al Anazi
OBJECTIVE: The aim of this in-vitro study was to investigate the marginal and internal fit of zirconia copings fabricated by five CAD/CAM (computer-aided design/computer-assisted manufacture) systems. METHOD AND MATERIALS: A typodont mandibular right first molar was prepared according to ideal parameters for a zirconia crown, scanned digitally, and 100 identical resin dies fabricated by 3D printing. Samples were randomly divided into five groups and sent to CAD/CAM systems for zirconia copings (A, Ceramill-Motion 2, Amann Girrbach; B, Weiland, Ivoclar Vivadent; C, Cerec, Ivoclar Vivadent; D, Prettau Zirconia, Zirkonzahn; E, Cad4dent)...
2018: Quintessence International
Natalie J Lemanski, Nina H Fefferman
One evolutionary view of aging, the disposable soma theory, suggests that an organism's rate of senescence depends on the amount of energy invested in somatic maintenance. Since organisms have limited energy to allocate among growth, maintenance, and reproduction, the optimal amount of energy to invest in maintenance is influenced by the probability of death from extrinsic causes and the effect of somatic investment on survival. In eusocial animals, the disposable soma theory can be used to explain colonies' energy investment in the longevity of workers, who act as the somatic elements of a superorganism...
June 2018: American Naturalist
Derek M Griffith
How might the science of men's health progress if research on marginalized or subordinated men is moved from the margins of the literature to the center? This commentary seeks to answer this question, suggesting that if more attention is paid to men of color and other marginalized men, the field will be greatly enriched in its ability to understand determinants of men's health. Reimagining men's health by moving men's health disparities to a primary focus of the field may yield critical new insights that would be essential to moving men's health to the center of health equity research...
May 1, 2018: American Journal of Men's Health
Habtamu K Benecha, John S Preisser, Kimon Divaris, Amy H Herring, Kalyan Das
Unlike zero-inflated Poisson regression, marginalized zero-inflated Poisson (MZIP) models for counts with excess zeros provide estimates with direct interpretations for the overall effects of covariates on the marginal mean. In the presence of missing covariates, MZIP and many other count data models are ordinarily fitted using complete case analysis methods due to lack of appropriate statistical methods and software. This article presents an estimation method for MZIP models with missing covariates. The method, which is applicable to other missing data problems, is illustrated and compared with complete case analysis by using simulations and dental data on the caries preventive effects of a school-based fluoride mouthrinse program...
May 11, 2018: Biometrical Journal. Biometrische Zeitschrift
Bas Vreugdenhil, Walter J F M van der Velden, Ton Feuth, Matthijs Kox, Peter Pickkers, Frank L van de Veerdonk, Nicole M A Blijlevens, Roger J M Brüggemann
BACKGROUND: Voriconazole (VCZ) exhibits a wide intra-patient pharmacokinetic variability, which is disadvantageous because of the narrow-therapeutic range of VCZ. A considerable part of this variation remains unexplainable despite extensive knowledge of this drug. It is hypothesized that inflammation has an impact on voriconazole pharmacokinetics. In this study we investigated the correlation between voriconazole trough concentrations and various cytokines. METHODS: A prospective single center analysis was performed in adult hematology patients receiving voriconazole for possible, probable or proven IFD...
May 9, 2018: British Journal of Clinical Pharmacology
Alessio Crippa, Andrea Discacciati, Matteo Bottai, Donna Spiegelman, Nicola Orsini
The standard two-stage approach for estimating non-linear dose-response curves based on aggregated data typically excludes those studies with less than three exposure groups. We develop the one-stage method as a linear mixed model and present the main aspects of the methodology, including model specification, estimation, testing, prediction, goodness-of-fit, model comparison, and quantification of between-studies heterogeneity. Using both fictitious and real data from a published meta-analysis, we illustrated the main features of the proposed methodology and compared it to a traditional two-stage analysis...
January 1, 2018: Statistical Methods in Medical Research
Alberto Gomez-Carballa, Jacobo Pardo-Seco, Stefania Brandini, Alessandro Achilli, Ugo A Perego, Michael D Coble, Toni M Diegoli, Vanesa Alvarez-Iglesias, Federico Martinon-Torres, Anna Olivieri, Antonio Torroni, Antonio Salas
Genetic and archaeological data indicate that the initial Paleoindian settlers of South America followed two entry routes separated by the Andes and the Amazon rainforest. The interactions between these paths and their impact on the peopling of South America remain unclear. Analysis of genetic variation in the Peruvian Andes and regions located South of the Amazon River might provide clues on this issue. We analyzed mitochondrial DNA variation at different Andean locations and >360,000 autosomal SNPs from 28 Native American ethnic groups to evaluate different trans-Andean demographic scenarios...
May 7, 2018: Genome Research
Cordula Hinkes, Birgit Schulze-Ehlers
The majority of farmed fish produced in Bangladesh is consumed domestically, while global demand for fish is increasing. Non-tariff barriers resulting from consumers' concerns about sustainability and food safety or attitudes towards the country of origin might be one reason for limited export. The purpose of this study is to analyze consumer preferences for frozen pangasius and tilapia fillets from Bangladesh in order to explore market opportunities in Germany. A discrete choice experiment was conducted to estimate marginal utilities and willingness-to-pay for different product attributes, focusing on sustainability certification and the country of origin...
May 4, 2018: Appetite
Sam Ali, Rosemary Kusaba Byanyima, Sam Ononge, Jerry Ictho, Jean Nyamwiza, Emmanuel Lako Ernesto Loro, John Mukisa, Angella Musewa, Annet Nalutaaya, Ronald Ssenyonga, Ismael Kawooya, Benjamin Temper, Achilles Katamba, Joan Kalyango, Charles Karamagi
BACKGROUND: Ultrasonography is essential in the prenatal diagnosis and care for the pregnant mothers. However, the measurements obtained often contain a small percentage of unavoidable error that may have serious clinical implications if substantial. We therefore evaluated the level of intra and inter-observer error in measuring mean sac diameter (MSD) and crown-rump length (CRL) in women between 6 and 10 weeks' gestation at Mulago hospital. METHODS: This was a cross-sectional study conducted from January to March 2016...
May 4, 2018: BMC Pregnancy and Childbirth
Elie E Daou, Hani Ounsi, Mutlu Özcan, Nadin Al-Haj Husain, Ziad Salameh
STATEMENT OF PROBLEM: Limited information is available on the precision of new metal processing technologies. PURPOSE: The purpose of this in vitro study was to evaluate the marginal and internal fit of pre-sintered cobalt-chromium (Co-Cr) and zirconia 3-unit fixed dental prostheses using x-ray microcomputed tomography. MATERIAL AND METHODS: Three-unit fixed dental prostheses were prepared on metal dies (N=12) using a typodont model from the maxillary first premolar to the first molar...
April 30, 2018: Journal of Prosthetic Dentistry
Ioannis Kioleoglou, Argirios Pissiotis, Michalakis Konstantinos
Background: The purpose of this study was to evaluate the accuracy of fitting of an implant supported screw-retained bar made on definitive casts produced by 4 different dental stone products. Material and Methods: The dental stones tested were QuickRock (Protechno), FujiRock (GC), Jade Stone (Whip Mix) and Moldasynt (Heraeus). Three external hexagon implants were placed in a polyoxymethylene block. Definitive impressions were made using monophase high viscosity polyvinylsiloxane in combination with custom trays...
March 2018: Journal of Clinical and Experimental Dentistry
Guy Paré, Chad Leaver, Claire Bourget
BACKGROUND: With the ever-increasing availability of mobile apps, consumer wearables, and smart medical devices, more and more individuals are self-tracking and managing their personal health data. OBJECTIVE: The aim of this study was to investigate the diffusion of the digital self-tracking movement in Canada. It provides a comprehensive, yet detailed account of this phenomenon. It examines the profile of digital self-trackers, traditional self-trackers, and nontrackers, further investigating the primary motivations for self-tracking and reasons for nontracking; barriers to adoption of connected care technologies; users' appreciation of their self-tracking devices, including what they perceive to be the main benefits; factors that influence people's intention to continue using connected care technologies in the future; and the reasons for usage discontinuance...
May 2, 2018: Journal of Medical Internet Research
Sven Achenbach, Garth Wells, Chen Shen
In deep X-ray lithography (DXRL), synchrotron radiation is applied to pattern polymer microstructures. At the Synchrotron Laboratory for Micro and Nano Devices (SyLMAND), Canadian Light Source, a chromium-coated grazing-incidence X-ray double-mirror system is applied as a tunable low-pass filter. In a systematic study, the surface conditions of the two mirrors are analyzed to determine the mirror reflectivity for DXRL process optimization, without the need for spectral analysis or surface probing: PMMA resist foils were homogeneously exposed and developed to determine development rates for mirror angles between 6 mrad and 12 mrad as well as for white light in the absence of the mirrors...
May 1, 2018: Journal of Synchrotron Radiation
Hyun-Wook Woo, Sung-Am Cho, Cheong-Hee Lee, Kyu-Bok Lee, Jin-Hyun Cho, Du-Hyeong Lee
PURPOSE: This study aimed to evaluate the marginal discrepancy of full-arch frameworks in implant-supported prostheses fabricated using pre-sintered soft alloy (PSA). MATERIALS AND METHODS: Full-arch metal frameworks were fabricated on the edentulous implant model using casting alloy (CA), fully-sintered hard alloy (FHA), and PSA (n = 4 in each group). To evaluate the misfit of the framework to the abutments, the absolute marginal discrepancy (AMD) values of the frameworks were measured in cross-sectional images that had been drawn as part of the triple-scan protocol...
April 2018: Journal of Advanced Prosthodontics
Sabine Navis, Aline Waterkeyn, Luc De Meester, Luc Brendonck
Recent studies have demonstrated that insect growth regulating insecticides are able to affect reproductive endpoints in zooplankton species at very low levels. For the cyclic parthenogenetic water flea Daphnia, most of this research has focused on the asexual part of the life cycle and induction of male offspring. Even though Daphnia and many other aquatic invertebrates rely on sexual reproduction and subsequent production of dormant eggs to recover from environmentally harsh conditions, much less is known about the effects of toxicants on the sexual reproductive phase...
April 26, 2018: Ecotoxicology
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