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https://www.readbyqxmd.com/read/28644150/rapid-fluorescence-lifetime-estimation-with-modified-phasor-approach-and-laguerre-deconvolution-a-comparative-study
#1
Farzad Fereidouni, Dimitris Gorpas, Dinglong Ma, Hussain Fatakdawala, Laura Marcu
Fluorescence lifetime imaging has been shown to serve as a valuable tool for interrogating and diagnosis of biological tissue at mesoscopic level. The ability to analyze fluorescence decay curves to extract lifetime values in real-time is crucial for clinical translation and applications such as tumor margin delineation or intracoronary imaging of atherosclerotic plaques. In this work, we compare the performance of two popular non-parametric (fit-free) methods for determining lifetime values from fluorescence decays in real-time -Phasor approach and Laguerre deconvolution...
June 23, 2017: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28636616/temnothorax-rugatulus-ant-colonies-consistently-vary-in-nest-structure-across-time-and-context
#2
Nicholas DiRienzo, Anna Dornhaus
A host of animals build architectural constructions. Such constructions frequently vary with environmental and individual/colony conditions, and their architecture directly influences behavior and fitness. The nests of ant colonies drive and enable many of their collective behaviors, and as such are part of their 'extended phenotype'. Since ant colonies have been recently shown to differ in behavior and life history strategy, we ask whether colonies differ in another trait: the architecture of the constructions they create...
2017: PloS One
https://www.readbyqxmd.com/read/28630034/fall-prevention-self-assessments-via-mobile-3d-visualization-technologies-community-dwelling-older-adults-perceptions-of-opportunities-and-challenges
#3
Julian Hamm, Arthur Money, Anita Atwal
BACKGROUND: In the field of occupational therapy, the assistive equipment provision process (AEPP) is a prominent preventive strategy used to promote independent living and to identify and alleviate fall risk factors via the provision of assistive equipment within the home environment. Current practice involves the use of paper-based forms that include 2D measurement guidance diagrams that aim to communicate the precise points and dimensions that must be measured in order to make AEPP assessments...
June 19, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28626864/detecting-genetic-association-through-shortest-paths-in-a-bidirected-graph
#4
Masao Ueki, Yoshinori Kawasaki, Gen Tamiya
Genome-wide association studies (GWASs) commonly use marginal association tests for each single-nucleotide polymorphism (SNP). Because these tests treat SNPs as independent, their power will be suboptimal for detecting SNPs hidden by linkage disequilibrium (LD). One way to improve power is to use a multiple regression model. However, the large number of SNPs preclude simultaneous fitting with multiple regression, and subset regression is infeasible because of an exorbitant number of candidate subsets. We therefore propose a new method for detecting hidden SNPs having significant yet weak marginal association in a multiple regression model...
June 19, 2017: Genetic Epidemiology
https://www.readbyqxmd.com/read/28624240/bipolar-bone-loss-in-patients-with-anterior-shoulder-dislocation-a-comparison-of-adolescents-versus-adult-patients
#5
Brian C Lau, Devin Conway, Patrick F Curran, Brian T Feeley, Nirav K Pandya
PURPOSE: To compare bipolar bone loss by evaluating the degree of glenoid bone loss, Hill-Sachs lesion size, and glenoid track in adolescents and adults with shoulder dislocations. METHODS: We performed a retrospective review between 2012 and 2016 of surgical and nonsurgical patients with a history of anterior shoulder dislocations (primary or recurrent) who underwent magnetic resonance imaging of the affected shoulder. The exclusion criteria included multidirectional instability, prior surgery, and posterior dislocation...
June 14, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28608435/cad-cam-fabricated-ceramic-implant-supported-single-crowns-made-from-lithium-disilicate-final-results-of-a-5-year-prospective-cohort-study
#6
Benedikt Christopher Spies, Stefano Pieralli, Kirstin Vach, Ralf-Joachim Kohal
BACKGROUND: All-ceramic bilayer systems suffer from technique-sensitivity, resulting in increased technical complication rates. This might be overcome by monolithic reconstructions, facilitating digital workflows. PURPOSE: To evaluate the clinical and patient-reported outcome of CAD/CAM-fabricated implant-supported single crowns (ISCs) made of lithium disilicate (LS2 ) cemented on ceramic implants 5 years after implant installation. MATERIALS AND METHODS: Twenty-four patients were included in the study...
June 13, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28607349/knee-symptomatic-osteoarthritis-walking-disability-nsaids-use-and-all-cause-mortality-population-based-wuchuan-osteoarthritis-study
#7
Qiang Liu, Jingbo Niu, Hu Li, Yan Ke, Rujun Li, Yuqing Zhang, Jianhao Lin
Knee symptomatic osteoarthritis (SxOA) was associated with all-cause mortality. Walking disability and NSAIDs use have been postulated as potential mechanisms linking knee SxOA to all-cause mortality. Data were collected on ability of walking for 1 kilometer and use of NSAIDs at baseline and death information at follow-up. Subjects with knee SxOA were identified if at least one knee had both radiographic OA and pain. We first fitted a Cox proportional hazards model to examine the relation of knee SxOA to the risk of all-cause mortality...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28606137/male-benefit-sexually-antagonistic-genotypes-show-elevated-vulnerability-to-inbreeding
#8
Karl Grieshop, David Berger, Göran Arnqvist
BACKGROUND: There is theoretical and empirical evidence for strong sexual selection in males having positive effects on population viability by serving to purify the genome of its mutation load at a low demographic cost. However, there is also theoretical and empirical evidence for negative effects of sexual selection on female fitness, and therefore population viability, known as the gender load. This can take the form of sexually antagonistic (SA) genetic variation where alleles with a selective advantage in males pose a detriment to female fitness, and vice versa...
June 12, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28602410/adjuvant-chemoradiation-after-surgical-resection-in-elderly-patients-with-high-risk-squamous-cell-carcinoma-of-the-head-and-neck-a-national-cancer-database-analysis
#9
Neil M Woody, Matthew C Ward, Shlomo A Koyfman, Chandana A Reddy, Jessica Geiger, Nikhil Joshi, Brian Burkey, Joseph Scharpf, Eric Lamarre, Brandon Prendes, David J Adelstein
PURPOSE: To determine the patterns of adjuvant chemoradiotherapy use in elderly patients treated with definitive surgical resection for squamous cell carcinoma of the head and neck with extracapsular extension (ECE) or positive margins and determine whether an association with overall survival (OS) exists with adjuvant concurrent chemoradiotherapy (CRT). METHODS AND MATERIALS: The National Cancer Database was queried to identify patients with SCC of the oral cavity, oropharynx, larynx, and hypopharynx who were treated with primary definitive surgery and adjuvant radiation therapy between 2004 and 2012...
July 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28595670/healthy-cognitive-ageing-in-the-lothian-birth-cohort-studies-marginal-gains-not-magic-bullet
#10
J Corley, S R Cox, I J Deary
In the face of shifting demographics and an increase in human longevity, it is important to examine carefully what is known about cognitive ageing, and to identify and promote possibly malleable lifestyle and health-related factors that might mitigate age-associated cognitive decline. The Lothian Birth Cohorts of 1921 (LBC1921, n = 550) and 1936 (LBC1936, n = 1091) are longitudinal studies of cognitive and brain ageing based in Scotland. Childhood IQ data are available for these participants, who were recruited in later life and then followed up regularly...
June 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28595032/comparing-prevalence-estimates-from-population-based-surveys-to-inform-surveillance-using-electronic-health-records
#11
Kathleen S Tatem, Matthew L Romo, Katharine H McVeigh, Pui Ying Chan, Elizabeth Lurie-Moroni, Lorna E Thorpe, Sharon E Perlman
INTRODUCTION: Electronic health record (EHR) systems provide an opportunity to use a novel data source for population health surveillance. Validation studies that compare prevalence estimates from EHRs and surveys most often use difference testing, which can, because of large sample sizes, lead to detection of significant differences that are not meaningful. We explored a novel application of the two one-sided t test (TOST) to assess the equivalence of prevalence estimates in 2 population-based surveys to inform margin selection for validating EHR-based surveillance prevalence estimates derived from large samples...
June 8, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28594079/development-of-the-breast-immobilization-system-in-prone-setup-the-effect-of-bra-in-prone-position-to-improve-the-breast-setup-error
#12
Mariko Kawamura, Yoshikazu Maeda, Kazutaka Yamamoto, Shigeyuki Takamatsu, Yoshitaka Sato, Hiroki Minami, Yusuke Saga, Kyo Kume, Yuji Tameshige, Makoto Sasaki, Hiroyasu Tamamura, Kouji Ohta, Yoshiyuki Itoh, Shinji Naganawa
PURPOSE/OBJECTIVE(S): Accurate and reproducible positioning of the breast is difficult due to its deformability and softness; thus, targeting a breast tumor or tumor bed with fractionated radiotherapy using external beam radiation is difficult. The aim of this study was to develop a novel bra to aid in breast immobilization in the prone position. MATERIALS & METHODS: To assess the accuracy of prone position fixation of breast tumors, 33 breast cancer patients with 34 lesions were recruited...
June 8, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28592303/assessing-the-efficiency-of-catch-up-campaigns-for-the-introduction-of-pneumococcal-conjugate-vaccine-a-modelling-study-based-on-data-from-pcv10-introduction-in-kilifi-kenya
#13
Stefan Flasche, John Ojal, Olivier Le Polain de Waroux, Mark Otiende, Katherine L O'Brien, Moses Kiti, D James Nokes, W John Edmunds, J Anthony G Scott
BACKGROUND: The World Health Organisation recommends the use of catch-up campaigns as part of the introduction of pneumococcal conjugate vaccines (PCVs) to accelerate herd protection and hence PCV impact. The value of a catch-up campaign is a trade-off between the costs of vaccinating additional age groups and the benefit of additional direct and indirect protection. There is a paucity of observational data, particularly from low- and middle-income countries, to quantify the optimal breadth of such catch-up campaigns...
June 7, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28590093/marginal-adaptation-and-internal-fit-of-posterior-3-unit-zirconia-fpds-fabricated-with-different-cad-cam-systems
#14
Maryam Memarian, Leyla Sadighpour, Rojman Nosratpour, Mohammad J K Fard
The purpose of this study was to compare the accuracy of zirconia FPDs fabricated by different laboratory CAD/CAM system. Thirty-six FPD zirconia frameworks were fabricated on corresponding epoxy resin models that were duplicated from a master model of mandibular second premolar and second molar mounted in an acrylic block to simulate missing first mandibular tooth. Frameworks were divided into groups (n = 12) of three laboratory CAD/CAM systems: Cercon, Amann Girrbach, and Zirkonzahn. For the two factors, system and abutment type, the absolute marginal discrepancy (AMD) was measured before cementation...
June 2017: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28586344/a-generalized-right-truncated-bivariate-poisson-regression-model-with-applications-to-health-data
#15
M Ataharul Islam, Rafiqul I Chowdhury
A generalized right truncated bivariate Poisson regression model is proposed in this paper. Estimation and tests for goodness of fit and over or under dispersion are illustrated for both untruncated and right truncated bivariate Poisson regression models using marginal-conditional approach. Estimation and test procedures are illustrated for bivariate Poisson regression models with applications to Health and Retirement Study data on number of health conditions and the number of health care services utilized...
2017: PloS One
https://www.readbyqxmd.com/read/28586234/the-direct-indirect-technique-for-composite-restorations-revisited
#16
André V Ritter, Newton Fahl, Marcos Vargas, Rodrigo R Maia
In the direct-indirect composite technique, composite is applied to a nonretentive tooth preparation (eg, a noncarious cervical lesion or a veneer/inlay/onlay preparation) without any bonding agent, sculpted to a primary anatomic form, and light-cured. The partially polymerized restoration is then removed from the preparation and finished and tempered extraorally chairside. The finished inlay is bonded to the preparation using a resin-based luting agent. Advantages of this technique include enhanced physical and mechanical properties afforded by the extraoral chairside tempering process because of increased monomer conversion, and greater operator control over the final marginal adaptation, surface finishing and polishing, and anatomy of the restoration, given that these elements are defined outside of the patient's mouth...
June 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28579654/trajectories-of-organized-activity-participation-among-urban-adolescents-associations-with-young-adult-outcomes
#17
Andria B Eisman, Sarah A Stoddard, José A Bauermeister, Cleopatra H Caldwell, Marc A Zimmerman
Organized activity participation provides opportunities for adolescents to develop assets that may support favorable outcomes in young adulthood. Activity participation may be especially beneficial for marginalized youth as they are likely to face stressors that increase risk of negative outcomes. We used growth mixture modeling (GMM) to identify activity participation trajectories among African American adolescents in an urban, disadvantaged community (Wave 1: mean age=14.86 years, SD=0.64; 49% male, N=681)...
May 2017: Journal of Community Psychology
https://www.readbyqxmd.com/read/28578984/comparison-of-dimensional-accuracy-of-conventionally-and-digitally-manufactured-intracoronal-restorations
#18
Reza Eftekhar Ashtiani, Leila Nasiri Khanlar, Minoo Mahshid, Alireza Moshaverinia
STATEMENT OF PROBLEM: Advances have been made in digital dentistry for the fabrication of dental prostheses, but evidence regarding the efficacy of digital techniques for the fabrication of intracoronal restorations is lacking. PURPOSE: The purpose of this in vitro study was to compare the dimensional accuracy of intracoronal restorations fabricated with digital and conventional techniques. MATERIAL AND METHODS: A sound mandibular molar tooth received a standard onlay preparation, and onlays were fabricated with 1 of 3 fabrication techniques...
June 2, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28578920/clinical-factors-and-dosimetry-associated-with-the-development-of-prostate-brachytherapy-related-urethral-strictures-a-matched-case-control-study
#19
Sandeep Singhal, Muhammad F Jamaluddin, Emma Lee, Ronald S Sloboda, Matthew Parliament, Nawaid Usmani
PURPOSE: Urethral strictures are a rare complication of prostate brachytherapy (BXT), with prior studies showing radiation dose to the bulbomembranous urethra as being associated with stricture formation. This retrospective case-control study explored clinical and dosimetric parameters associated with the development of BXT-related urethral strictures. METHODS AND MATERIALS: A cohort of 34 patients developed urethral strictures after BXT at our institution for the period of 2008-2014...
May 31, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28574584/composite-marginal-quantile-regression-analysis-for-longitudinal-adolescent-body-mass-index-data
#20
Chi-Chuan Yang, Yi-Hau Chen, Hsing-Yi Chang
Childhood and adolescenthood overweight or obesity, which may be quantified through the body mass index (BMI), is strongly associated with adult obesity and other health problems. Motivated by the child and adolescent behaviors in long-term evolution (CABLE) study, we are interested in individual, family, and school factors associated with marginal quantiles of longitudinal adolescent BMI values. We propose a new method for composite marginal quantile regression analysis for longitudinal outcome data, which performs marginal quantile regressions at multiple quantile levels simultaneously...
June 2, 2017: Statistics in Medicine
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