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https://www.readbyqxmd.com/read/28530664/flexible-information-routing-by-transient-synchrony
#1
Agostina Palmigiano, Theo Geisel, Fred Wolf, Demian Battaglia
Perception, cognition and behavior rely on flexible communication between microcircuits in distinct cortical regions. The mechanisms underlying rapid information rerouting between such microcircuits are still unknown. It has been proposed that changing patterns of coherence between local gamma rhythms support flexible information rerouting. The stochastic and transient nature of gamma oscillations in vivo, however, is hard to reconcile with such a function. Here we show that models of cortical circuits near the onset of oscillatory synchrony selectively route input signals despite the short duration of gamma bursts and the irregularity of neuronal firing...
May 22, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28530256/can-the-onset-of-orbital-cancer-be-the-result-of-a-prosthetic-eye
#2
A Croce, V Mastronardi, M Laus, E Festa Kotelnikova
Orbital exenteration is a disfiguring procedure performed for unresponsive orbital infections and control of recurrent benign tumours and malignancies arising from the eyelids (basal cell carcinoma, squamous cell carcinoma, conjunctival malignant melanoma), lachrymal glands (adenoid cystic carcinoma) or surrounding sinuses. In extremely rare cases the use of a prosthetic eye after enucleation can lead to anophthalmic socket tumours. We report the case of a 54-year-old man who had left eye enucleation due to recurring events of retinal detachment and who developed an invasive fast growing epidermoid carcinoma 30 years later...
May 22, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28530225/a-canonical-neural-mechanism-for-behavioral-variability
#3
Ran Darshan, William E Wood, Susan Peters, Arthur Leblois, David Hansel
The ability to generate variable movements is essential for learning and adjusting complex behaviours. This variability has been linked to the temporal irregularity of neuronal activity in the central nervous system. However, how neuronal irregularity actually translates into behavioural variability is unclear. Here we combine modelling, electrophysiological and behavioural studies to address this issue. We demonstrate that a model circuit comprising topographically organized and strongly recurrent neural networks can autonomously generate irregular motor behaviours...
May 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/28529749/chondroblastic-osteosarcoma-arising-in-the-maxilla-mimicking-the-radiographic-and-histological-characteristics-of-cemento-osseous-lesions-a-case-report
#4
Bin-Bin Li, Jian-Yun Zhang, Yan Gao
Osteosarcomas of the jaw are comparatively rare and represent only 2-10% of all osteosarcomas. We herein present a rare case of an osteosarcoma exhibiting the radiographic and histological characteristics of cemento-osseous lesions in the alveolar ridge of the maxilla. A 53-year-old male patient presented with the complaint of gradual swelling of the left maxilla over 4 years. Radiography revealed an ill-defined radioopaque mass, intimately associated with the apices of the involved teeth, without a periosteal reaction...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28529743/omental-synovial-sarcoma-mimicking-an-ovarian-malignancy-a-case-report
#5
Naoyuki Iwahashi, Yoko Deguchi, Yuko Horiuchi, Kazuhiko Ino, Kenichi Furukawa
Synovial sarcoma is clinically rare, and cases of synovial sarcoma arising in the omentum are particularly rare. Only 3 cases have been reported in the literature to dtae, and they were associated with a poor prognosis. We herein report a rare case of aggressive primary omental synovial sarcoma presenting as an ovarian malignancy. A 53-year-old multigravida woman was referred to our hospital due to progressive abdominal distension. Magnetic resonance imaging revealed a large heterogeneous mass with an irregular component occupying the lower abdominal cavity, with an intact uterus...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28529671/the-advection-of-microparticles-mcf-7-and-mda-mb-231-breast-cancer-cells-in-response-to-very-low-reynolds-numbers
#6
Sinéad T Morley, Michael T Walsh, David T Newport
The lymphatic system is an extensive vascular network that serves as the primary route for the metastatic spread of breast cancer cells (BCCs). The dynamics by which BCCs travel in the lymphatics to distant sites, and eventually establish metastatic tumors, remain poorly understood. Particle tracking techniques were employed to analyze the behavior of MCF-7 and MDA-MB-231 BCCs which were exposed to lymphatic flow conditions in a 100 μm square microchannel. The behavior of the BCCs was compared to rigid particles of various diameters (η = dp/H= 0...
May 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28528853/sarcomatoid-renal-cell-carcinoma-and-collecting-duct-carcinoma-discrimination-from-common-renal-cell-carcinoma-subtypes-and-benign-rcc-mimics-on-multiphasic-mdct
#7
Jonathan R Young, Jocelyn A Young, Daniel J A Margolis, Steven Sauk, James Sayre, Allan J Pantuck, Steven S Raman
RATIONALE AND OBJECTIVES: To investigate whether imaging features on multiphasic multidetector computed tomography (MDCT) can help discriminate sarcomatoid renal cell carcinoma (RCC) and collecting duct carcinoma (CDC) from other solid renal masses. MATERIALS AND METHODS: With institutional review board approval for this HIPAA-compliant study, we derived a cohort of 7 sarcomatoid RCCs, 4 CDCs, 165 clear cell RCCs, 56 papillary RCCs, 22 chromophobe RCCs, 49 oncocytomas, and 16 lipid-poor angiomyolipomas with preoperative multiphasic MDCT with up to four phases (unenhanced, corticomedullary, nephrographic, and excretory)...
May 18, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28528435/benefits-of-a-regular-vs-irregular-rhythm-based-training-programme-on-physical-fitness-and-motor-skills-in-obese-girls
#8
Ghazi Racil, Wassim Elmontassar, Imen Rommene, Claire Tourny, Anis Chaouachi, Jeremy B Coquart
PURPOSE: The aim of the current study was to examine the impact of a physical exercise programme including rhythmic elements (regular and irregular tempos) on physiological variables, motor skills (MS), and jump performances in obese girls. METHODS: Thirty-six obese girls (age: 10.4 ± 0.9 years, body mass: 58.7 ± 4.0 kg, height: 1.37 ± 0.04 m, body mass index: 31.2 ± 2.1) participated in three weekly physical exercise sessions for 6 weeks, with each session consisting of basic fundamental locomotor movements...
May 20, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28528263/influences-of-land-use-and-antecedent-dry-weather-period-on-pollution-level-and-ecological-risk-of-heavy-metals-in-road-deposited-sediment
#9
Jin Zhang, Pei Hua, Peter Krebs
Road-deposited sediment and its adsorbed pollutants have been regarded as significant sources of urban diffuse pollution. In this study, the solid-phase concentrations (mg/g), surface load (mg/m(2)) and chemical fractionation of zinc (Zn), copper (Cu) and cadmium (Cd) were determined. Geo-accumulation (Igeo) and ecological risk (RI) indexes were employed for metal risk assessment. Results show that the highest solid-phase concentrations of Zn and Cu were usually found at an industrial area. However, Cd had the highest solid-phase concentrations at a rural area, followed by a commercial area...
May 18, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28527987/studies-of-chitosan-pectin-complexes-exposed-to-uv-radiation
#10
Jolanta Kowalonek
Chitosan and pectin form complexes owing to electrostatic interactions between positively charged amino groups in chitosan and negatively charged carboxylate groups in pectin, which was confirmed by ATR-FTIR spectroscopy and contact angle measurements. Moreover, the formation of these complexes might be associated with the loss of the biopolymers ordering, which resulted in higher surface roughness and lower thermal stability of the complexes in comparison to those of homopolymers. UV rays, used as a sterilizing agent, caused a moderate increase in the surface polarity of the complexes...
May 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28525993/translation-and-validation-of-the-finnish-version-of-index-of-dental-anxiety-and-fear-idaf-4c-%C3%A2-among-dental-students
#11
Mimmi Tolvanen, Katri Puijola, Jason M Armfield, Satu Lahti
BACKGROUND: Dental fear accounts for 41% of the non-habitual dental attendance such as visiting only when in pain among adult Finns. Dentists should be able to recognize patients in risk for irregular attendance due to dental fear and measure their fear with valid and reliable instrument that capture the multidimensionality of dental fear. The study's aim was to translate the Index of Dental Anxiety and Fear (IDAF-4C+) into Finnish and test its reliability and validity. METHODS: The study population consisted of dental students in a Finnish university (n = 202)...
May 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28525273/directional-fluid-gating-by-janus-membranes-with-heterogeneous-wetting-properties-for-selective-oil-water-separation
#12
Prashant Gupta, Balasubramanian Kandasubramanian
The rising oil seepage accidents evolved into a global issue necessitating immediate counter measure to abridge its catastrophic repercussions on sensitive marine ecosystem urging innovative techniques for effective oil/water separation. Here, we report surface tailored wettability modified superhydrophobic/superoleophilic Janus membrane by impregnating non-ionic surfactant stabilized nano-sized polytetrafluoroethylene (PTFE) dispersion polymerized via non-fluorinated processing aid onto cotton substrate using Meyer rod coating technique, exhibiting excellent separation efficiency up to 98% with various petroleum products and retaining its intrinsic properties for at least 30 recurrences...
May 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28524830/using-ultrasonography-to-evaluate-the-relationship-between-capsular-invasion-or-extracapsular-extension-and-lymph-node-metastasis-in-papillary-thyroid-carcinomas
#13
Wei-Ping Jiao, Lei Zhang
BACKGROUND: Previous studies have demonstrated that ultrasonography is the recommended imaging modality for preoperative staging of papillary thyroid carcinomas (PTCs). However, only a few studies have kept watch on preoperative evaluation of capsular invasion (CI) or extracapsular extension (ECE) and cervical lymph node metastasis using preoperative ultrasonography. This study aimed to investigate the relationship between the CI or ECE and the cervical lymph node metastasis in PTCs using preoperative ultrasonography and postoperative pathology in Chinese patients...
June 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28524242/women-with-vulvodynia-awareness-and-knowledge-of-its-care-among-student-healthcare-staff
#14
Minna Törnävä, Meeri Koivula, Mika Helminen, Tarja Suominen
BACKGROUND: Many women with vulvodynia are women of fertile age, and this syndrome may cause many physical and psychosexual functional disorders. Women with vulvodynia often find that healthcare professionals seem to demonstrate a lack of awareness about the syndrome and its care. These issues have not been previously studied among student healthcare staff. AIM: To investigate awareness and knowledge about vulvodynia and its care among staff in the student healthcare sector in Finland...
May 19, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28524147/-complex-treatment-results-in-a-congenital-glaucoma-patient-case-report
#15
O L Fabrikantov, S I Nikolashin, Yu V Matrosova, V A Kozlov, A E Kopylov, E S Pirogova
Early diagnosis of congenital glaucoma allows surgery to be performed at the stage of reversible glaucomatous alterations of the optic disc and retina. In primary congenital glaucoma, the main reason for visual acuity reduction following surgical stabilization of the intraocular pressure are corneal changes. These include an increased corneal diameter, Haab's striae, areas of thickening and a greater posterior elevation. The resultant irregular astigmatism leads to amblyopia and a marked decrease in visual acuity...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28523937/attentional-set-shifting-and-social-abilities-in-children-with-schizotypal-and-comorbid-autism-spectrum-disorders
#16
Ahmad Abu-Akel, Renee R Testa, Harvey P Jones, Nola Ross, Efstratios Skafidas, Bruce Tonge, Christos Pantelis
OBJECTIVE: While diagnostically independent, autism and schizotypal disorders can co-occur. Their concurrent impact on outcomes and phenotypes has not been investigated. We investigated the impact of comorbid autism and schizotypal disorders in children on executive functioning and socio-pragmatic skills - core features of both disorders. METHOD: Executive functioning (assessed with the Cambridge Neuropsychological Test Automated Battery) and socio-pragmatic skills (assessed using the Melbourne Assessment of Schizotypy in Kids) were investigated in a total of 67 (6-12 year old) children with autism ( n = 15; M/F = 10/5), schizotypal disorder ( n = 8; M/F = 5/3) and comorbid autism and schizotypal disorder ( n = 12; M/F = 5/7) and typically developing children ( n = 32; M/F = 17/15)...
May 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28522409/neonatal-exposure-to-17%C3%AE-ethynyl-estradiol-ee-disrupts-follicle-development-and-reproductive-hormone-profiles-in-female-rats
#17
Haolin Zhang, Kazuyoshi Taya, Kentaro Nagaoka, Midori Yoshida, Gen Watanabe
Toxic effects induced by exposure to endocrine-disrupting chemicals during fetal and neonatal periods can be irreversible and exert effects throughout an animal's entire life. Our previous study showed that neonatal exposure to 17α-ethynyl estradiol (EE) induced irregular estrous cycle in adults. To uncover the reason for the delayed effect after neonatal exposure to EE, reproductive parameters including ovarian weight, ovarian steroidogenesis, and hormonal profiles were investigated in developing female rats...
May 15, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28522398/study-on-the-synthesis-and-physicochemical-properties-of-starch-acetate-with-low-substitution-under-microwave-assistance
#18
Derong Lin, Wei Zhou, Jingjing Zhao, Weijie Lan, Rongming Chen, Yutong Li, Baoshan Xing, Zhuohao Li, Mengshi Xiao, Zhijun Wu, Xindan Li, Rongna Chen, Xingwen Zhang, Hong Chen, Qing Zhang, Wen Qin, Suqing Li
In this study, synthesis and physicochemical properties of starch acetate with low substitution under microwave were studied. A three-level-three-factorial Central Composite Design using Response Surface Methodology was employed to optimize the reaction conditions. The optimal parameters are as follows: amount of acetic anhydride of 12%, radiation time of 11min, and microwave power of 100W. These optimal conditions predicted by RSM were confirmed that the degree of substitution (DS) of acetate starch is 0.0691mg/g and the physical and chemical properties of natural corn starch (NCS) and corn starch acetate (ACS) were further studied...
May 15, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28521983/design-of-interpenetrating-chitosan-and-poly-ethylene-glycol-sponges-for-potential-drug-delivery-applications
#19
Lisa Racine, Guillaume Costa, Eric Bayma-Pecit, Isabelle Texier, Rachel Auzély-Velty
Semi-interpenetrating chitosan (CS)/poly(ethylene glycol) (PEG) sponges were designed by crosslinking PEG in the CS matrix via nucleophilic thiol-yne addition. This reaction does not require the use of any potentially cytotoxic catalytic species and offers possibilities to prepare materials with tunable properties. The molecular structure of the sponges was analyzed by FTIR spectroscopy, which provided evidence of intermolecular interactions between PEG and CS, and the presence of a cross-linked PEG network in the CS matrix...
August 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28521804/sero-prevalence-of-virus-neutralizing-antibodies-for-rabies-in-different-groups-of-dogs-following-vaccination
#20
R M S Pimburage, M Gunatilake, O Wimalaratne, A Balasuriya, K A D N Perera
BACKGROUND: Mass vaccination of dogs is considered fundamental for national rabies control programmes in Sri Lanka, as dog is the main reservoir and transmitter of the disease. METHODS: Dogs were followed to determine the sero-prevalence of antibodies to the rabies virus. Altogether 510 previously vaccinated and unvaccinated dogs with owners (domestic dogs) and dogs without owners (stray dogs) of the local guard dog breed in different age groups recruited from Kalutara District, Sri Lanka...
May 18, 2017: BMC Veterinary Research
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