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https://www.readbyqxmd.com/read/28918265/amorphous-liquid-metal-electrodes-enabled-conformable-electrochemical-therapy-of-tumors
#1
Xuyang Sun, Bo Yuan, Wei Rao, Jing Liu
Electrochemical treatment of tumors (EChT) has recently been identified as a very effective way for local tumor therapy. However, hindered by the limited effective area of a single rigid electrode, multiple electrodes are often recruited when tackling large tumors, where too many electrodes not only complicate the clinical procedures but also aggravate patients' pain. Here we present a new conceptual electric stimulation tumor therapy through introducing the injectable liquid metal electrodes, which can adapt to complex tumor shapes so as to achieve desired therapeutic performance...
September 5, 2017: Biomaterials
https://www.readbyqxmd.com/read/28917911/injectable-glycosaminoglycan-protein-nano-complex-in-semi-interpenetrating-networks-a-biphasic-hydrogel-for-hyaline-cartilage-regeneration
#2
Janani Radhakrishnan, Anuradha Subramanian, Swaminathan Sethuraman
Articular hyaline cartilage regeneration remains challenging due to its less intrinsic reparability. The study develops injectable biphasic semi-interpenetrating polymer networks (SIPN) hydrogel impregnated with chondroitin sulfate (ChS) nanoparticles for functional cartilage restoration. ChS loaded zein nanoparticles (∼150nm) prepared by polyelectrolyte-protein complexation were interspersed into injectable SIPNs developed by blending alginate with poly(vinyl alcohol) and calcium crosslinking. The hydrogel exhibited interconnected porous microstructure (39...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917894/structural-functional-and-ph-sensitive-release-characteristics-of-water-soluble-polysaccharide-from-the-seeds-of-albizia-lebbeck-l
#3
Chekuri Ashok Kumar Varma, K Jayaram Kumar
Plant polysaccharides, generally regarded as safe (GRAS), are gaining importance as excipients in drug delivery. Therefore, the current paper presents the studies on structural, functional and drug release study of water soluble polysaccharide (ALPS) from seeds of Albizia lebbeck L. High swelling, water holding capacity, foam stability and lower moisture content suggests its use as additive in food preparations. The apparent molecular weight of polysaccharide was found to be 1.98×10(2)kDa. Monosaccharide composition analysis indicated that ALPS consists of mannose (4...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917678/optical-frequency-domain-imaging-versus-intravascular-ultrasound-in-percutaneous-coronary-intervention-opinion-trial-results-from-the-opinion-imaging-study
#4
Hiromasa Otake, Takashi Kubo, Hachidai Takahashi, Toshiro Shinke, Takayuki Okamura, Kiyoshi Hibi, Gaku Nakazawa, Yoshihiro Morino, Junya Shite, Tetsuya Fusazaki, Ken Kozuma, Tetsuya Ioji, Hideaki Kaneda, Takashi Akasaka
OBJECTIVES: We sought to clarify how intravascular ultrasound (IVUS) and optical coherence tomography affect percutaneous coronary intervention (PCI) with current-generation drug-eluting stents in a pre-specified substudy of the OPINION (OPtical frequency domain imaging versus INtravascular ultrasound in percutaneous coronary interventiON) trial, a multicenter, prospective, randomized, noninferiority trial comparing optical frequency domain imaging (OFDI)-guided PCI with IVUS-guided PCI...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28917477/using-a-slit-knife-to-facilitate-mohs-micrographic-surgery-in-irregularly-shaped-areas
#5
José Francisco Millán-Cayetano, Inés Fernández-Canedo, Alberto Ortega-Sánchez, Magdalena de Troya-Martín
No abstract text is available yet for this article.
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28917414/chemical-and-physical-analysis-of-phaco-handpiece-tip-surfaces-before-and-after-cataract%C3%A2-surgery
#6
Paolo Cecchini, Rossella D'Aloisio, Manlio Antonuccio, Gianluca Turco, Federica Bondino, Elena Magnano, Marta Di Nicola, Daniele Tognetto
PURPOSE: To evaluate the surface chemical composition and roughness of different phaco tips before and after their use during cataract surgery. SETTING: Eye Clinic, University of Trieste, Trieste, Italy. DESIGN: Experimental study. METHODS: Of the 66 tips studied, 33 (15 new, 15 after single use, and 3 after multiple uses) were studied with X-ray photoemission spectroscopy and 33 (15 new, 15 after single use, and 3 after multiple uses) were examined using scanning electron microscopy with energy dispersive X-ray spectroscopy analysis and contact profilometry...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28916905/small-cholangiolocellular-carcinoma-that-was-difficult-to-distinguish-from-cholangiocellular-carcinoma-a-case-report
#7
Norihiro Ishii, Kenichiro Araki, Takahiro Yamanaka, Tadashi Handa, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Shinichi Aishima, Hiroyuki Kuwano, Ken Shirabe
BACKGROUND: Cholangiolocellular carcinoma (CoCC) is thought to be derived from hepatic progenitor cells. Because of its origin, CoCC has diverse clinicopathological and imaging findings. Here, we report a case of small CoCC that was difficult to diagnose preoperatively. CASE PRESENTATION: A 62-year-old woman was confirmed with a small liver nodule in the left lobe 2 years after a sustained virological response of hepatitis C virus. The size of the nodule was 11...
September 15, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28916671/atrial-fibrillation-detection-fishing-for-an-irregular-heartbeat-before-and-after-stroke
#8
REVIEW
Vincent Thijs
No abstract text is available yet for this article.
September 15, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28916319/inhibition-of-growth-and-biofilm-formation-of-clinical-bacterial-isolates-by-nio-nanoparticles-synthesized-from-eucalyptus-globulus-plants
#9
Samia Saleem, Bilal Ahmed, Mohammad Saghir Khan, Majed Al-Shaeri, Javed Musarrat
Nanotechnology based therapeutics has emerged as a promising approach for augmenting the activity of existing antimicrobials due to the unique physical and chemical properties of nanoparticles (NPs). Nickel oxide nanoparticles (NiO-NPs) have been suggested as prospective antibacterial and antitumor agent. In this study, NiO-NPs have been synthesized by a green approach using Eucalyptus globulus leaf extract and assessed for their bactericidal activity. The morphology and purity of synthesized NiO-NPs determined through various spectroscopic techniques like UV-Visible, FT-IR, XRD, EDX and electron microscopy differed considerably...
September 12, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28916041/polydopamine-functionalized-poly-ether-ether-ketone-tube-for-capillary-electrophoresis-mass-spectrometry
#10
Wei Zhou, Wenpeng Zhang, Yikun Liu, Xinhong Yu, Zilin Chen
Capillary electrophoresis-mass spectrometry (CE-MS) is a hyphenated technique that combines the advantages like low sample consumption, high separation efficiency, short analytical time in CE and high sensitivity, powerful molecular structure elucidation in MS. Polyimide-coated fused silica capillary has become the most dominant capillary for CE, but it suffers from swelling and aminolysis of polyimide coating when treated with organic solvents and alkaline buffer in the CE-MS interface in which the polyimide coating at the end of the capillary is exposed to the solution, and this phenomenon can result in current instability, irregular electrospray and clogging at outlet after prolonged use...
September 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28915893/dosimetric-comparison-of-different-treatment-modalities-for-stereotactic-radiotherapy
#11
Shih-Ming Hsu, Yuan-Chun Lai, Chien-Chung Jeng, Chia-Ying Tseng
BACKGROUND: The modalities for performing stereotactic radiotherapy (SRT) on the brain include the cone-based linear accelerator (linac), the flattening filter-free (FFF) volumetric modulated arc therapy (VMAT) linac, and tomotherapy. In this study, the cone-based linac, FFF-VMAT linac, and tomotherapy modalities were evaluated by measuring the differences in doses delivered during brain SRT and experimentally assessing the accuracy of the output radiation doses through clinical measurements...
September 16, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28915862/self-detection-of-atrial-fibrillation-in-an-aged-population-three-year-follow-up-of-the-lietoaf-intervention-study
#12
Jussi Jaakkola, Raine Virtanen, Tuija Vasankari, Marika Salminen, K E Juhani Airaksinen
BACKGROUND: Atrial fibrillation (AF) is often asymptomatic and undiagnosed until an ischaemic stroke occurs. An irregular pulse is a key manifestation of AF. We assessed whether pulse self-palpation is feasible in screening of AF. METHODS: Altogether 205 residents of Lieto municipality aged ≥75 years were randomized in 2012 to receive brief education on pulse palpation focusing on evaluating rhythm regularity. Self-detected pulse irregularity and new AF diagnoses were recorded, and the subjects' quality of life and use of health care services were assessed during a three-year follow-up...
September 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28915295/error-type-and-lexical-frequency-effects-error-detection-in-swedish-children-with-language-impairment
#13
Anna Eva Hallin, Christina Reuterskiöld
Purpose: The first aim of this study was to investigate if Swedish-speaking school-age children with language impairment (LI) show specific morphosyntactic vulnerabilities in error detection. The second aim was to investigate the effects of lexical frequency on error detection, an overlooked aspect of previous error detection studies. Method: Error sensitivity for grammatical structures vulnerable in Swedish-speaking preschool children with LI (omission of the indefinite article in a noun phrase with a neuter/common noun, and use of the infinitive instead of past-tense regular and irregular verbs) was compared to a control error (singular noun instead of plural)...
September 14, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28915279/first-consensus-on-primary-prevention-and-early-intervention-in-aesthetic-medicine
#14
Marina Landau, Chytra V Anand, Thierry Besins, Yates Yen Yu Chao, Sabrina Guillen Fabi, Uliana Gout, Martina Kerscher, Tatjana Pavicic, Peter Hsien Li Peng, Berthold Rzany, Gerhard Sattler, Tunk Tiryaki, Heidi A Waldorf, Andre Braz
BACKGROUND: Facial aging is a complex interplay of extrinsic and intrinsic factors leading to progressive changes in the skin, subcutaneous tissue, and bone. Clinical experience suggests that early aesthetic intervention may slow the signs of aging, but treatment in the absence of symptoms or with minimal signs of aging has not yet been properly addressed. OBJECTIVES: To provide treatment recommendations for primary prevention and early intervention in individuals with no or minimal signs of aging...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28914983/suggesting-the-cytologic-diagnosis-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-a-retrospective-analysis-of-atypical-and-suspicious-nodules
#15
Kyle C Strickland, Brooke E Howitt, Justine A Barletta, Edmund S Cibas, Jeffrey F Krane
BACKGROUND: The term "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) has replaced a subset of follicular variant of papillary thyroid carcinoma due to the indolent behavior of such tumors. NIFTPs are most often classified in an "indeterminate" diagnostic category. In the current study, the authors sought to identify cytologic features helpful in distinguishing NIFTP from other entities in these categories, particularly benign nodules. METHODS: The authors retrospectively evaluated a consecutive cohort of 130 thyroid fine-needle aspiration (FNA) specimens with an indeterminate diagnosis and available histopathologic follow-up...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28914672/endometrial-changes-in-surgical-specimens-of-perimenopausal-patients-treated-with-ulipristal-acetate-for-uterine-leiomyomas
#16
Francisco F Nogales, Vicente Crespo-Lora, Nelly Cruz-Viruel, Clara Chamorro-Santos, Christine Bergeron
Ulipristal acetate (UPA) is used to treat leiomyomas, and its effect on the endometrium has been studied in biopsy material. Reversible histologic modifications were found, named progesterone receptor modulators-associated endometrial changes (PAEC). However, hysterectomies from patients treated with UPA have not been analyzed. For the first time, we examined surgical specimens from 100 leiomyoma-treated patients for UPA-related endometrial changes. We analyzed the distribution of lesions, involution after treatment, and the relationship between type and extent of lesions and dosage...
September 13, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28914632/stepwise-guided-photorefractive-keratectomy-in-treatment-of-irregular-astigmatism-after-penetrating-keratoplasty-and-deep-anterior-lamellar-keratoplasty
#17
Nir Sorkin, Adi Einan-Lifshitz, Sagi Abelson, Tanguy Boutin, Mahmood Showail, Armand Borovik, Zach Ashkenazy, Clara C Chan, David S Rootman
PURPOSE: To report the outcome of stepwise ablation using topography-guided photorefractive keratectomy to treat irregular astigmatism after either penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK). METHODS: This is a retrospective, interventional analysis including patients with irregular astigmatism after either PKP or DALK, who underwent topography-guided photorefractive keratectomy. The entire cohort was analyzed, as well as the PKP and DALK groups separately...
September 12, 2017: Cornea
https://www.readbyqxmd.com/read/28913844/synergetic-metals-on-carbocatalyst-shungite
#18
Martin Pumera
The natural occurring Palaeoproterozoic carbon mineral shungite is a complex raw carbon microporous matrix, loaded with a wide range of elements. Shungite.exhibits disordered and amorphous structure with highly irregular building blocks. Shungite incorporates metals in its structure, typically catalytic elements such Fe and Ni are also present, as well as, the toxic elements Pb and As at mg/g level. We show here that incorporation of the metals in the carbon matrix of shungite leads into synergiustic catalytic effect...
September 15, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28913830/ontogenesis-of-opercular-deformities-in-gilthead-sea-bream-sparus-aurata-a-histological-description
#19
N P Thuong, B Verstraeten, B D Kegel, J Christiaens, T D Wolf, P Sorgeloos, D Bonte, D Adriaens
The aim of this study was to characterize histological changes during opercular osteogenesis in farmed gilthead sea bream Sparus aurata larvae from 7 to 69 days post hatching (dph) and compare normal osteogenesis with that of deformed opercles. Mild opercular deformities were first detected in 19 dph larvae by folding of the opercle's distal edge into the gill chamber. Here, the variation in the phenotype and the irregular bone structure at the curled part of the opercles is described and compared with the histology of normal opercles...
September 15, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28913509/effects-of-single-segment-intacs-implantation-on-visual-acuity-and-corneal-topographic-indices-of-keratoconus
#20
Kazem Amanzadeh, Roghiyeh Elham, Ebrahim Jafarzadepur
PURPOSE: To assess the changes in visual acuity and topographic indices after implantation of single-segment Intacs. METHODS: Forty-two keratoconic eyes received Femtosecond-assisted single-segment Intacs. Uncorrected distance visual acuity (UDVA) and best spectacle corrected visual acuity (BSCVA), refractive error, keratometry (K1, K2, Km, and KMax.), and seven Pentacam measured topographical indices; index of surface variance (ISV), index of vertical asymmetry (IVA), keratoconus index (KI), central keratoconus index (CKI), index of height asymmetry (IHA), index of height decentration (IHD), and minimum radius of curvature (R Min) were assessed 4 months after surgery...
September 2017: Journal of Current Ophthalmology
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