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https://www.readbyqxmd.com/read/29928031/management-of-tuberculosis-by-healthcare-practitioners-in-pakistan-a-systematic-review
#1
Christy A Braham, Peter J White, Nimalan Arinaminpathy
OBJECTIVE: To assess the quality of tuberculosis (TB) care in Pakistan, through determining comparison of healthcare practitioners' knowledge and practices to national and international TB care guidelines. METHODS: Studies reporting on knowledge, attitudes and practices of public and private practitioners with TB patients were selected through searching electronic databases and grey literature. FINDINGS: Of 1458 reports, 20 full-texts were assessed, of which 11 met the eligibility and quality criteria; all studies focused on private sector care...
2018: PloS One
https://www.readbyqxmd.com/read/29927988/factors-affecting-serum-concentration-of-vancomycin-in-critically-ill-oliguric-pediatric-patients-receiving-continuous-venovenous-hemodiafiltration
#2
Bongjin Lee, Soo Jung Kim, June Dong Park, Jiun Park, Ae Hee Jung, Sun Hoi Jung, Yu Hyeon Choi, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong
Vancomycin is known to be unintentionally eliminated by continuous renal replacement therapy, and the protein bound fraction of vancomycin is also known to be different in adults and children. However, there are only a few studies investigating the relationship between the dose of continuous venovenous hemodiafiltration (CVVHDF) parameters and serum concentration of vancomycin in pediatric patients. The aim of this study was to determine clinical and demographic parameters that significantly affect serum vancomycin concentrations...
2018: PloS One
https://www.readbyqxmd.com/read/29927667/using-sertraline-in-postpartum-and-breastfeeding-balancing-risks-and-benefits
#3
Alessandro Cuomo, Giuseppe Maina, Stephen M Neal, Graziella De Montis, Gianluca Rosso, Simona Scheggi, Bruno Beccarini Crescenzi, Simone Bolognesi, Arianna Goracci, Anna Coluccia, Fabio Ferretti, Andrea Fagiolini
The World Health Organization recommends newborns to be breastfed but this may be challenging if the mother needs to be treated for depression, since strong evidence to inform treatment choice is missing. Areas covered: We provide a critical review of the literature to guide clinicians who are considering sertraline for the management of depression during postpartum. Expert opinion: Sertraline is one of the safest antidepressants during breastfeeding. In most cases, women already taking sertraline should be advised to breastfeed and continue the medication...
June 21, 2018: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/29925575/implementation-of-duchenne-muscular-dystrophy-care-considerations
#4
Jennifer G Andrews, Kristin Conway, Christina Westfield, Christina Trout, F John Meaney, Katherine Mathews, Emma Ciafaloni, Christopher Cunniff, Deborah J Fox, Dennis Matthews, Shree Pandya
BACKGROUND: Duchenne muscular dystrophy (DMD) is an X-linked disorder characterized by progressive muscle weakness and multisystem involvement. Recent advances in management of individuals with DMD have prolonged survival. Lack of standardized care spurred an international collaboration to develop consensus-based care considerations for diagnosis and management. In this study, we evaluate adherence to considerations at selected sites. METHODS: We collaborated with the Muscular Dystrophy Surveillance, Tracking, and Research Network...
June 20, 2018: Pediatrics
https://www.readbyqxmd.com/read/29922848/establishing-a-multidisciplinary-head-and-neck-clinical-pathway-an-implementation-evaluation-and-audit-of-dysphagia-related-services-and-outcomes
#5
Barbara Pisano Messing, Elizabeth C Ward, Cathy Lazarus, Keri Ryniak, Melissa Kim, Jessica Silinonte, Dorothy Gold, Carol B Thompson, Karen T Pitman, Ray Blanco, Ryan Sobel, Karen Harrer, Karen Ulmer, Geoffrey Neuner, Kruti Patel, Mei Tang, Gregory Lee
Head and neck cancer (HNC) guidelines recommend regular multidisciplinary team (MDT) monitoring and early intervention to optimize dysphagia outcomes; however, many factors affect the ability to achieve these goals. The aims of this study were to explore the barriers/facilitators to establishing and sustaining a MDT HNC care pathway and to examine the dysphagia-related speech-language pathology (SLP) and dietetic components of the pathway. Using the Consolidated Framework for Implementation Research (CFIR), a mixed methods study design was used to evaluate an established MDT HNC pathway...
June 19, 2018: Dysphagia
https://www.readbyqxmd.com/read/29915747/audit-of-emergency-obstetric-referrals-from-a-secondary-level-hospital-in-haryana-north-india
#6
Shashi Kant, Ravneet Kaur, Sumit Malhotra, Partha Haldar, Akhil Dhanesh Goel
Background: The maternal mortality ratio in India is high. An effective emergency obstetric care (EmOC) strategy has been identified as a priority to reduce maternal deaths. Since the capacity of different levels of public health facilities to provide EmOC is varied, an effective referral system is crucial. However, few studies have evaluated the functioning and quality of referral systems in India. A systematic monitoring of referrals helps to identify current gaps in the provision of essential obstetric care...
January 2018: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29915435/lifestyle-intervention-using-internet-of-things-iot-for-the-elderly-a-study-protocol-for-a-randomized-control-trial-the-best-life-study
#7
Sawako Kato, Masahiko Ando, Takaaki Kondo, Yasuko Yoshida, Hiroyuki Honda, Shoichi Maruyama
Modification of lifestyle habits, including diet and physical activity, is essential for the prevention and control of type 2 diabetes mellitus (T2DM) in elderly patients. However, individualized treatment is more critical for the elderly than for general patients. This study aimed to determine lifestyle interventions that resulted in lowering hemoglobin A1c (HbA1c ) in Japanese pre- and early diabetic elderly subjects. The BEST-LIFE trial is an ongoing, open-label, 6-month, randomized (1:1) parallel group trial...
May 2018: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29914858/telemedicine-use-among-caregivers-of-cancer-patients-systematic-review
#8
REVIEW
Chiara Marzorati, Chiara Renzi, Samuel William Russell-Edu, Gabriella Pravettoni
BACKGROUND: The number of published studies and systematic reviews examining different telehealth interventions targeting patients and their effects on patients' well-being and quality of life have grown in recent decades. However, the use of telemedicine tools aimed at the family members and caregivers of adult cancer patients is less defined. OBJECTIVE: We aimed to conduct a systematic review to provide a more complete picture regarding telemedicine tools for informal caregivers (usually family members or close friends) implemented in all phases of cancer care...
June 18, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29913734/understanding-the-link-between-depression-and-pain
#9
Steven J Linton, Sofia Bergbom
Background and aims Patients seeking care for a pain problem very often also report symptoms of depression.In fact, depression is associated with the development of chronic pain as well as poor treatment results. Yet, the mechanisms by which depression and pain impact upon one another are not clear. This paper provides a critical review of the literature with the aim of shedding light on the relationship between pain and depression. Further, we introduce the Örebro Behavioral Emotion Regulation Model which may stimulate understanding in addition to research...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913375/versatile-graphene-biosensors-for-enhancing-human-cell-therapy
#10
REVIEW
George M Vlăsceanu, Roxana-Maria Amărandi, Mariana Ioniță, Teddy Tite, Horia Iovu, Luisa Pilan, Jorge S Burns
Technological advances in engineering and cell biology stimulate novel approaches for medical treatment, in particular cell-based therapy. The first cell-based gene therapy against cancer was recently approved by the US Food and Drug Administration. Progress in cancer diagnosis includes a blood test detecting five cancer types. Numerous stem cell phase I/II clinical trials showing safety and efficacy will soon pursue qualifying criteria for advanced therapy medicinal products (ATMP), aspiring to join the first stem-cell therapy approved by the European Medicines Agency...
May 1, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29912937/comparison-of-three-non-invasive-hemodynamic-monitoring-methods-in-critically-ill-children
#11
Chanapai Chaiyakulsil, Marut Chantra, Poomiporn Katanyuwong, Anant Khositseth, Nattachai Anantasit
INTRODUCTION: Hemodynamic parameters measurements were widely conducted using pulmonary artery catheter (PAC) with thermodilution as a reference standard. Due to its technical difficulties in children, transthoracic echocardiography (TTE) has been widely employed instead. Nonetheless, TTE requires expertise and is time-consuming. Noninvasive cardiac output monitoring such as ultrasonic cardiac output monitor (USCOM) and electrical velocimetry (EV) can be performed rapidly with less expertise requirement...
2018: PloS One
https://www.readbyqxmd.com/read/29912815/monitoring-self-reported-adherence-to-antiretroviral-therapy-in-public-hiv-care-facilities-in-brazil-a-national-cross-sectional-study
#12
Maria Altenfelder Santos, Mark Drew Crosland Guimarães, Ernani Tiaraju Santa Helena, Cáritas Relva Basso, Felipe Campos Vale, Wania Maria do Espírito Santo Carvalho, Ana Maroso Alves, Gustavo Machado Rocha, Francisco de Assis Acurcio, Maria das Graças Braga Ceccato, Rogério Ruscitto do Prado, Paulo Rossi Menezes, Maria Ines Batistella Nemes
INTRODUCTION: Patient adherence to antiretroviral therapy (ART) is critical for HIV treatment success. Monitoring rates of adherence in public HIV outpatient care facilities can improve outcomes in Brazil where ART is universally available. METHODS: We conducted a national cross-sectional survey of ART adherence in 2010. Participants were selected using a multistage probability sample. First, HIV outpatient care facilities were stratified according to 7 Organizational Quality Classification (OQC) groups and regions...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29909126/factors-associated-with-delirium-in-critical-patients-in-a-health-institution-in-bucaramanga-colombia
#13
C C Torres-Contreras, A N Páez-Esteban, A Hinestrosa-Díaz Del Castillo, M K Rincón-Romero, A Amaris-Vega, J P Martínez-Patiño
OBJECTIVE: To determine the incidence and the factors associated with delirium in intensive care unit patients. METHODS: A cohort study conducted on 134 patients in the intensive care unit at a clinic in Bucaramanga, Colombia., who were recruited in the first 24hours following admission and on whom the Richmond Agitation-Sedation Scale (RASS), PRE-DELIRIC version in Spanish, and Confusion Assessment method for Intensive Care Unit (CAM-ICU) were applied; the outcome was evaluated through daily monitoring with CAM-ICU...
June 13, 2018: Enfermería Intensiva
https://www.readbyqxmd.com/read/29907274/a-targeted-management-approach-to-cardiogenic-shock
#14
REVIEW
Mithun Chakravarthy, Masaki Tsukashita, Srinivas Murali
Cardiogenic shock is a clinical syndrome characterized by low cardiac output and sustained tissue hypoperfusion resulting in end-organ dysfunction and death. In-hospital mortality rates range from 50% to 60%. Urgent diagnosis, timely transfer to a tertiary or quaternary medical facility with critical care management capabilities and multidisciplinary shock teams is a must to increase survival. Aggressive, hemodynamically guided medical management with careful monitoring of clinical and hemodynamic parameters with timely use of appropriate mechanical circulatory support devices is often necessary...
July 2018: Critical Care Clinics
https://www.readbyqxmd.com/read/29907211/comparison-of-dexmedetomidine-versus-propofol-on-hemodynamics-in-surgical-critically-ill-patients
#15
Ya-Fei Chang, Anne Chao, Po-Yuan Shih, Yen-Chun Hsu, Chen-Tse Lee, Yu-Wen Tien, Yu-Chang Yeh, Lee-Wei Chen
BACKGROUND: Sedation with dexmedetomidine and propofol may cause hypotension or bradycardia. This study aimed to compare the effects of dexmedetomidine and propofol on hemodynamics and clinical outcomes in surgical intensive care unit (ICU) patients after major abdominal surgery. MATERIALS AND METHODS: Enrolled patients were randomly allocated to the dexmedetomidine or propofol group. Cardiac index was measured using a continuous noninvasive cardiac output monitor on the basis of chest bioreactance...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29907209/using-artificial-intelligence-to-predict-prolonged-mechanical-ventilation-and-tracheostomy-placement
#16
Joshua Parreco, Antonio Hidalgo, Jonathan J Parks, Robert Kozol, Rishi Rattan
BACKGROUND: Early identification of critically ill patients who will require prolonged mechanical ventilation (PMV) has proven to be difficult. The purpose of this study was to use machine learning to identify patients at risk for PMV and tracheostomy placement. MATERIALS AND METHODS: The Multiparameter Intelligent Monitoring in Intensive Care III database was queried for all intensive care unit (ICU) stays with mechanical ventilation. PMV was defined as ventilation >7 d...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29906203/radiographic-review-of-current-therapeutic-and-monitoring-devices-in-the-chest
#17
Christopher J G Sigakis, Susan K Mathai, Thomas D Suby-Long, Nicole L Restauri, Daniel Ocazionez, Tami J Bang, Carlos S Restrepo, Peter B Sachs, Daniel Vargas
Chest radiographs are obtained as a standard part of clinical care. Rapid advancements in medical technology have resulted in a myriad of new medical devices, and familiarity with their imaging appearance is a critical yet increasingly difficult endeavor. Many modern thoracic medical devices are new renditions of old designs and are often smaller than older versions. In addition, multiple device designs serving the same purpose may have varying morphologies and positions within the chest. The radiologist must be able to recognize and correctly identify the proper positioning of state-of-the-art medical devices and identify any potential complications that could impact patient care and management...
June 15, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29905521/contrast-enhanced-ultrasound-to-visualize-hemodynamic-changes-after-rodent-spinal-cord-injury
#18
Zin Z Khaing, Lindsay N Cates, Dane M DeWees, Alexander Hannah, Pierre Mourad, Matthew Bruce, Christoph P Hofstetter
OBJECTIVE Traumatic spinal cord injury (tSCI) causes an almost complete loss of blood flow at the site of injury (primary injury) as well as significant hypoperfusion in the penumbra of the injury. Hypoperfusion in the penumbra progresses after injury to the spinal cord and is likely to be a major contributor to progressive cell death of spinal cord tissue that was initially viable (secondary injury). Neuroprotective treatment strategies seek to limit secondary injury. Clinical monitoring of the temporal and spatial patterns of blood flow within the contused spinal cord is currently not feasible...
June 15, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29904605/women-s-recall-of-maternal-and-newborn-interventions-received-in-the-postnatal-period-a-validity-study-in-kenya-and-swaziland
#19
Katharine J McCarthy, Ann K Blanc, Charlotte E Warren, Brian Mdawida
Background: Despite the concentration of maternal and infant deaths in the early postnatal period, information on the content and quality of postnatal care interventions is not routinely collected in most low and middle-income countries. At present, data on the coverage of postnatal care interventions mostly rely on women's reports collected in household surveys, such as the Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS), which collect limited information...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29904451/thrombolysis-is-an-effective-and-safe-therapy-in-stuck-mitral-valves-with-delayed-presentation-as-well-as-hemodynamically-unstable-patients-a-single-centre-study
#20
Arun Shivajirao Bade, Shakil Sattar Ahmed Shaikh, Hemant Khemani, Gurkirat Singh, Narender Omprakash Bansal
Background: Thrombosis is a complication of prosthetic valves on oral anticoagulants which is associated with significant morbidity and mortality. A re-operation carries a substantial risk, with mortality rate from 10% to 15% in selected series, which may be 2- or 3-folds higher in critically ill patients. This study conducted in a tertiary care cardiology unit aimed to evaluate the effectiveness and safety of thrombolytic therapy in stuck mitral bileaflet heart valves. Methods: As a prospective observational study, clinical symptoms and fluoroscopy were the mainstay in diagnosis of stuck mitral valve...
June 2018: Cardiology Research
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