keyword
MENU ▼
Read by QxMD icon Read
search

Complicated skin and skin structure infection

keyword
https://www.readbyqxmd.com/read/28812401/management-of-complicated-skin-and-skin-structure-infections-a-call-for-infectious-disease-specialists
#1
Arne Tärnvik
No abstract text is available yet for this article.
August 16, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28800526/identification-and-determination-of-related-substances-of-ceftaroline-fosamil-in-medicinal-product-by-high-performance-liquid-chromatography-with-diode-array-detection-and-tandem-mass-spectrometry
#2
Izabela Karpiuk, Katarzyna Michalska, Katarzyna Bus, Monika Kiljan, Stefan Tyski
Ceftaroline fosamil, the prodrug of ceftaroline, is an advanced-generation cephalosporin antibacterial agent approved for treatment in the European Union in 2012. The drug is dedicated to curing complicated skin and soft tissue infections and community-acquired pneumonia. The developed analytical method of high performance liquid chromatography (HPLC) followed by diode array detector (DAD) set at 243nm was used to identify and determine degradation products of ceftaroline fosamil. The elaborated method demonstrated good selectivity and linearity [r>0...
August 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28795212/a-review-of-adverse-events-related-to-prostatic-artery-embolization-for-treatment-of-bladder-outlet-obstruction-due-to-bph
#3
Airton Mota Moreira, André Moreira de Assis, Francisco Cesar Carnevale, Alberto Azoubel Antunes, Miguel Srougi, Giovanni Guido Cerri
INTRODUCTION: Minimally invasive procedures have gained great importance among the treatments for benign prostate hyperplasia (BPH) due to their low morbidity. Prostate artery embolization has emerged as a safe and effective alternative for patients with large volume BPH, not suited for surgery. MATERIALS AND METHODS: Low adverse events rates have been reported following prostate artery embolization and may include dysuria, urinary infection, hematuria, hematospermia, acute urinary retention and rectal bleeding...
August 9, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28789580/a-potential-benefit-from-infectious-disease-specialist-and-stationary-ward-in-rational-antibiotic-therapy-of-complicated-skin-and-skin-structure-infections
#4
Iiro H Jääskeläinen, Lars Hagberg, Tommy Schyman, Asko Järvinen
BACKGROUND: Management practices of complicated skin and skin structure infections (cSSSI) were compared between two areas with similar healthcare structure and low prevalence of antimicrobial resistance. METHODS: The high affinity to public health-care in the Nordic countries enabled population-based approach used in this retrospective study. The study population (n = 460) consisted of all adult residents from Helsinki (Finland) and Gothenburg (Sweden) treated in hospital due to cSSSI during 2008-2011...
August 8, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28695347/telavancin-in-the-treatment-of-concurrent-staphylococcus-aureus-bacteremia-a-retrospective-analysis-of-atlas-and-attain-studies
#5
Samuel E Wilson, Donald R Graham, Whedy Wang, Jon B Bruss, Bibiana Castaneda-Ruiz
INTRODUCTION: Concurrent Staphylococcus aureus bacteremia (SAB) worsens outcomes and increases mortality in patients with complicated skin and skin structure infections (cSSSI), hospital-acquired bacterial pneumonia, and ventilator-associated bacterial pneumonia (HABP/VABP). These challenges highlight the need for alternative treatments. Telavancin (TLV), a bactericidal lipoglycopeptide with high in vitro potency, effectively treats patients with cSSSI and HABP/VABP caused by Gram-positive pathogens, particularly S...
July 10, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/28693050/long-term-results-of-fixation-free-incisional-hernia-repair-using-a-tentacle-shaped-implant
#6
Giuseppe Amato, Giorgio Romano, Thorsten Goetze, Luca Gordini, Enrico Erdas, Fabio Medas, Piergiorgio Calò
INTRODUCTION: The fixation and the overlap of the mesh represent an open issue in incisional hernia repair. An exclusively designed prosthesis has been developed to assure a suture-free repair and a broader coverage of the abdominal wall. This study describes the long-term results of incisional hernia procedures carried out positioning a tentacle-shaped implant through a specifically developed surgical technique. MATERIALS AND METHODS: A proprietary symmetrically-shaped flat mesh constituted by a large central body with integrated radiating arms was used to repair incisional hernias in 68 patients...
July 25, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28638013/-surgical-treatment-of-diabetic-neuroosteoarthropathy-dnoap-and-its-long-term-results
#7
V M Bensman, Yu P Savchenko, S E Gumenyuk, K G Triandafilov, P P Vasil'chenko, S N Pyatakov, V V Khoritonenko
AIM: To develop pathogenetically justified surgical treatment of diabetic neuroosteoarthropathy (DNOAP). MATERIAL AND METHODS: 52 patients were operated and long-term results were studied in 36 of them. 2 groups were assessed depending on completeness of surgical treatment including changed synovial structures removal. Tarso-metatarsal arthrodesis was created after synovectomy in median foot to restore longitudinal arch. Cruro-calcaneal neoarthrosis was performed after elimination of posterior focus of DNOAP...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28634536/telavancin-a-novel-semisynthetic-lipoglycopeptide-agent-to-counter-the-challenge-of-resistant-gram-positive-pathogens
#8
REVIEW
Biswadeep Das, Chayna Sarkar, Debasmita Das, Amit Gupta, Arnav Kalra, Shubham Sahni
Telavancin (TD-6424), a semisynthetic lipoglycopeptide vancomycin-derivative, is a novel antimicrobial agent developed by Theravance for overcoming resistant Gram-positive bacterial infections, specifically methicillin-resistant Staphylococcus aureus (MRSA). The US Food and Drug Administration (USFDA) had approved telavancin in 2009 for the treatment of complicated skin and skin structure infections (cSSSIs) caused by Gram-positive bacteria, including MRSA (S. aureus, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus anginosus group, or Enterococcus faecalis)...
March 2017: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/28520605/reducing-postsurgical-wound-complications-a-critical-review
#9
Barbara Delmore, Joshua Mitchell Cohen, Daniel O'Neill, Andy Chu, Vinh Pham, Ernest Chiu
GENERAL PURPOSE: To provide information on risk factors for surgical site infections (SSIs) and actions to mitigate that risk. TARGET AUDIENCE: This continuing education activity is intended for surgeons, surgical teams, physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant should be better able to:1...
June 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28470021/microbiological-etiology-and-treatment-of-complicated-skin-and-skin-structure-infections-in-diabetic-and-nondiabetic-patients-in-a-population-based-study
#10
Iiro H Jääskeläinen, Lars Hagberg, Erik Forsblom, Asko Järvinen
BACKGROUND: Diabetes is a major risk factor for skin and skin structure infection (SSSI), and the global burden of diabetics with SSSI is enormous. The more complex microbiology of diabetic foot infection (DFI) is well established, but it is not known whether microbiological etiology differs between diabetics and nondiabetics in other disease entities under the umbrella of complicated SSSI (cSSSI). METHODS: This retrospective, population-based study included patients with cSSSI, and it was conducted in 2 Nordic cities with a low prevalence of antimicrobial resistance...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28427244/whole-genome-expression-analyses-of-type-2-diabetes-in-human-skin-reveal-altered-immune-function-and-burden-of-infection
#11
Chun Wu, Xiaopan Chen, Jing Shu, Chun-Ting Lee
Skin disorders are among most common complications associated with type 2 diabetes mellitus (T2DM). Although T2DM patients are known to have increased risk of infections and other T2DM-related skin disorders, their molecular mechanisms are largely unknown. This study aims to identify dysregulated genes and gene networks that are associated with T2DM in human skin. We compared the expression profiles of 56,318 transcribed genes on 74 T2DM cases and 148 gender- age-, and race-matched non-diabetes controls from the Genotype-Tissue Expression (GTEx) database...
May 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28413772/postoperative-complications-with-cryotherapy-in-bone-tumors
#12
REVIEW
Clark Chen, John Garlich, Katie Vincent, Earl Brien
The technique of cryosurgery has been used to control local recurrence in a variety of benign and malignant bone tumors. Early studies revealed significant complication rates (25%) that included fracture, infection, and soft tissue injury. Our method of cryosurgery has yielded excellent tumor control with improved complication rates. The objective of this study is to determine the characteristics of postoperative complications after pouring liquid nitrogen into curettaged bone defects, and to review our current indications and surgical technique in bone tumor management...
June 2017: Journal of Bone Oncology
https://www.readbyqxmd.com/read/28408096/local-treatment-of-a-pharyngocutaneous-fistula-secondary-to-osteoradionecrosis
#13
Olga González-Antolín
Radionecrosis is a late, and difficult to treat,complication of radiotherapy performed on head and neck tumours, and it is difficult to treat. This process causes significant damage, not only in the skin, but also in muscular, nervous, vascular, and bone structures. This, in turn, leads to airway and digestive tract involvement, as well as a functional loss and a cosmetic defect that usually requires reconstructive surgery. Therefore, this process is associated with a significant loss in the quality of life of patients and involves a long hospital stay for treatment, as well as the necessary support measures...
April 10, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28368977/cutaneous-burn-injury-promotes-shifts-in-the-bacterial-microbiome-in-autologous-donor-skin-implications-for-skin-grafting-outcomes
#14
Jennifer K Plichta, Xiang Gao, Huaiying Lin, Qunfeng Dong, Evelyn Toh, David E Nelson, Richard L Gamelli, Elizabeth A Grice, Katherine A Radek
INTRODUCTION: The cutaneous microbiome maintains skin barrier function, regulates inflammation, and stimulates wound healing responses. Burn injury promotes an excessive activation of the cutaneous and systemic immune response directed against commensal and invading pathogens. Skin grafting is the primary method of reconstructing full-thickness burns, and wound infection continues to be a significant complication. METHODS: In this study, the cutaneous bacterial microbiome was evaluated and subsequently compared to patient outcomes...
March 31, 2017: Shock
https://www.readbyqxmd.com/read/28343752/efficacy-of-tedizolid-against-methicillin-resistant-staphylococcus-aureus-and-peptostreptococcus-anaerobius-in-thigh-mixed-infection-mouse-model
#15
Yuka Yamagishi, Hiroshige Mikamo, Hideo Kato, Naoya Nishiyama, Nobuhiro Asai, Yusuke Koizumi, Daisuke Sakanashi, Hiroyuki Suematsu, Katsuhiko Matsuura, Mao Hagihara
OBJECTIVE: The purpose of this study is to compare the antimicrobial activity of human simulated exposures of tedizolid 200 mg daily, and linezolid 600 mg every 12 h for the treatment of complicated skin and skin structure infection (cSSSI) caused by MRSA and Peptostreptococcus anaerobius in both the neutropenic mice thigh mixed-infection models. MATERIAL AND METHOD: Tedizolid phosphate and linezolid were used for all in vivo testing. A total of one MRSA and two P...
March 23, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28334482/minimising-central-line-associated-bloodstream-infection-rate-in-inserting-central-venous-catheters-in-the-adult-intensive-care-units
#16
REVIEW
Hedaya Rateb Hina, Joan R S McDowell
AIMS AND OBJECTIVES: To investigate the procedural aspects in inserting central venous catheters that minimise central line-associated bloodstream infection rates in adult intensive care units through a structured literature review. BACKGROUND: In adult intensive care units, central line-associated bloodstream infections are a major cause of high mortality rates and increased in costs due to the consequences of complications. METHODS: Eligible articles were identified by combining indexed keywords using Boolean operator of "AND" under databases of Ovid and CINAHL...
March 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28299217/management-of-retained-genital-piercings-a-case-report-and-review
#17
Laura J Moulton, Amelia M Jernigan
The prevalence of genital piercing among women is increasing. As the popularity increases, the number of complications from infection, injury, and retained jewelry is likely to rise. Techniques to remove embedded jewelry are not well described in the literature. The purpose of this report was to describe a case of a patient with a retained clitoral glans piercing, discuss a simple technique for outpatient removal, and review current evidence regarding associated risks of clitoral piercings. A 24-year-old female presented to the emergency department with an embedded clitoral glans piercing...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28288455/diagnostic-tools-for-doctors-evaluation-of-tattoo-complications
#18
Jørgen Serup
Diagnosis of tattoo complications is a multi-facetted field since many clinical entities and disease mechanisms are represented. Infections, allergies, and pigment foreign body reactions with granuloma are the major groups. The clinician needs a structured approach to diagnosis and an armamentarium of standard tests. Diagnosis primarily builds on patient history, objective clinical examination, and punch biopsy, supplemented with microbiology testing, ultrasound scanning, and clinical photography. Evaluation of allergic tattoo reactions and allergy to pigments by patch testing is not applicable and has a falsely negative outcome except for the diagnosis of allergy to metals and preservatives...
2017: Current Problems in Dermatology
https://www.readbyqxmd.com/read/28274771/factors-associated-with-time-to-clinical-stability-in-complicated-skin-and-skin-structure-infections
#19
I H Jääskeläinen, L Hagberg, E Forsblom, A Järvinen
OBJECTIVES: Factors associated with the time to clinical stability in patients with complicated skin and skin structure infection (cSSSI) were analysed in a retrospective population-based study. METHODS: All hospitalized patients (n=402) with cSSSI in two Nordic cities during a 4-year period were included. Patient, disease, and treatment related factors were analysed in relation to early (0-3 days) or late (≥4 days) clinical stability. Clinical stability was assessed as improvement of infection related local and systemic signs...
March 6, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28202770/daptomycin-for-complicated-skin-infections-a-randomized-trial
#20
RANDOMIZED CONTROLLED TRIAL
John Bradley, Chad Glasser, Hernando Patino, Sandra R Arnold, Antonio Arrieta, Blaise Congeni, Robert S Daum, Tsoline Kojaoghlanian, Minjung Yoon, Diane Anastasiou, Dominik J Wolf, Paula Bokesch
BACKGROUND: Complicated skin and skin structure infections (cSSSI) are common in children. Due to safety and resistance issues with recommended agents, new treatment options would be advantageous. METHODS: Multicenter, evaluator-blinded clinical trial. Patients 1 to 17 years old with cSSSI caused by Gram-positive pathogens were randomized 2:1 to intravenous daptomycin or standard-of-care (SOC) treatment for ≤14 days. Daptomycin was administered once daily with dosing by patient age: 12 to 17 years, 5 mg/kg; 7 to 11 years, 7 mg/kg; 2 to 6 years, 9 mg/kg; 12 to 23 months, 10 mg/kg...
March 2017: Pediatrics
keyword
keyword
15674
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"