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Chronic back pain

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https://www.readbyqxmd.com/read/28829518/cost-of-opioid-treated-chronic-low-back-pain-findings-from-a-pilot-randomized-controlled-trial-of-mindfulness-meditation-based-intervention
#1
Aleksandra E Zgierska, James Ircink, Cindy A Burzinski, Marlon P Mundt
OBJECTIVE: Opioid-treated chronic low back pain (CLBP) is debilitating, costly, and often refractory to existing treatments. This secondary analysis aims to pilot-test the hypothesis that mindfulness meditation (MM) can reduce economic burden related to opioid-treated CLBP. DESIGN: Twenty-six-week unblinded pilot randomized controlled trial, comparing MM, adjunctive to usual-care, to usual care alone. SETTING: Outpatient. PARTICIPANTS: Thirty-five adults with opioid-treated CLBP (≥30 morphine-equivalent mg/day) for 3 + months enrolled; none withdrew...
May 2017: Journal of Opioid Management
https://www.readbyqxmd.com/read/28828123/migration-of-innumerable-chronically-retained-acupuncture-needles
#2
Frances Lazarow, R Hampton Andrews, Jonathan Revels, Sarah Shaves
We present a case of a 50-year-old female with a 2-day history of back and abdominal pain who was discovered to have innumerable chronically retained acupuncture needles, which had migrated throughout her abdomen and pelvis. Although many of these needles were in precarious positions, including the epidural space, renal parenchyma, small bowel, and vasculature, there was no evidence for acute injury. We also briefly discuss evidence for the magnetic resonance imaging compatibility of acupuncture needles. Although a rare complication, given the high frequency of acupuncture therapy in the United States, physicians must be aware of the potential for retained and migrated needles...
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28827229/safety-and-feasibility-of-transcranial-direct-current-stimulation-tdcs-combined-with-sensorimotor-retraining-in-chronic-low-back-pain-a-protocol-for-a-pilot-randomised-controlled-trial
#3
Adam Louis Ouellette, Matthew B Liston, Wei-Ju Chang, David M Walton, Benedict Martin Wand, Siobhan M Schabrun
INTRODUCTION: Chronic low back pain (LBP) is a common and costly health problem yet current treatments demonstrate at best, small effects. The concurrent application of treatments with synergistic clinical and mechanistic effects may improve outcomes in chronic LBP. This pilot trial aims to (1) determine the feasibility, safety and perceived patient response to a combined transcranial direct current stimulation (tDCS) and sensorimotor retraining intervention in chronic LBP and (2) provide data to support a sample size calculation for a fully powered trial should trends of effectiveness be present...
August 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28822475/an-observational-study-on-recurrences-of-low-back-pain-during-the-first-12-months-after-chiropractic-treatment
#4
Christina Knecht, Barry Kim Humphreys, Brigitte Wirth
OBJECTIVES: The purpose of this study was to investigate recurrence rate and prognostic factors in a large population of patients with low back pain (LBP) up to 1 year after chiropractic care using standardized definitions. METHODS: In Switzerland, 722 patients with LBP (375 male; mean age = 44.5 ± 13.8 years) completed the Numeric Rating Scale for pain (NRS) and the Oswestry Disability Index (ODI) before treatment and 1, 3, 6, and 12 months later (ODI up to 3 months)...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28820231/interventions-for-treating-persistent-pain-in-survivors-of-torture
#5
REVIEW
Emma Baird, Amanda C de C Williams, Leslie Hearn, Kirstine Amris
BACKGROUND: Persistent (chronic) pain is a frequent complaint in survivors of torture, particularly but not exclusively pain in the musculoskeletal system. Torture survivors may have no access to health care; where they do, they may not be recognised when they present, and the care available often falls short of their needs. There is a tendency in state and non-governmental organisations' services to focus on mental health, with poor understanding of persistent pain, while survivors may have many other legal, welfare, and social problems that take precedence over health care...
August 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28818984/pseudo-reference-regions-for-glial-imaging-with-11-c-pbr28-investigation-in-two-clinical-cohorts
#6
Daniel Strakis Albrecht, Marc David Normandin, Sergey Shcherbinin, Dustin W Wooten, Adam J Schwarz, Nicole R Zurcher, Vanessa N Barth, Nicolas J Guehl, Oluwaseun Johnson-Akeju, Nazem Atassi, Mattia Veronese, Federico Turkheimer, Jacob M Hooker, Marco Luciano Loggia
The translocator protein (TSPO) is a commonly used imaging target to investigate neuroinflammation. While TSPO imaging demonstrates great promise, its signal exhibits substantial interindividual variability, which needs to be accounted for to uncover group effects that are truly reflective of neuroimmune activation. Recent evidence suggests that relative metrics computed using pseudo-reference approaches can minimize within-group variability, and increase sensitivity to detect physiologically meaningful group differences...
August 17, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28814894/startle-modulation-by-heat-pain-with-varying-threat-levels-in-chronic-pain-patients-and-pain-free-controls
#7
C Horn-Hofmann, D Wolf, S Wolff, M Heesen, K Knippenberg-Bigge, P M Lang, S Lautenbacher
BACKGROUND: Empirical evidence suggests that affective responses to pain are changed in chronic pain. The investigation of startle responses to pain might contribute to clarifying whether such alterations also expand to motivational defensive reactions. We aimed at comparing startle responses to tonic heat pain with high threat (HT) or low threat (LT) in patients with chronic musculoskeletal pain and controls. As pain-related anxiety and catastrophizing are typically elevated in chronic pain, we expected to find stronger startle responses in patients specifically under experimental HT...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28814385/gabapentinoids-should-not-be-used-for-chronic-low-back-pain-meta-analysis-concludes
#8
Jacqui Wise
No abstract text is available yet for this article.
August 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28810129/opioid-prescribing-for-chronic-pain-in-a-community-based-healthcare-system
#9
Robert J Romanelli, Laurence I Ikeda, Braden Lynch, Terri Craig, Joseph C Cappelleri, Trevor Jukes, Denis Y Ishisaka
OBJECTIVES: We sought to evaluate opioid prescribing in an ambulatory setting among patients with noncancer chronic pain (CP). STUDY DESIGN: Cross-sectional analysis. METHODS: We identified patients with at least 2 CP encounters at least 30 days apart in 2012 in the electronic health records of a community-based healthcare delivery system in northern California. We used logistic regression models to assess associations of receiving an opioid prescription with respect to number and type of CP conditions and patient demographics and characteristics...
May 1, 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28809936/benefits-and-safety-of-gabapentinoids-in-chronic-low-back-pain-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#10
Harsha Shanthanna, Ian Gilron, Manikandan Rajarathinam, Rizq AlAmri, Sriganesh Kamath, Lehana Thabane, Philip J Devereaux, Mohit Bhandari
BACKGROUND AND OBJECTIVE: Chronic Low Back Pain (CLBP) is very common, with a lifetime prevalence between 51% and 80%. In majority, it is nonspecific in nature and multifactorial in etiology. Pregabalin (PG) and Gabapentin (GB) are gabapentinoids that have demonstrated benefit in neuropathic pain conditions. Despite no clear rationale, they are increasingly used for nonspecific CLBP. They necessitate prolonged use and are associated with adverse effects and increased cost. Recent guidelines from the National Health Service (NHS), England, expressed concerns on their off-label use, in addition to the risk of misuse...
August 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28807894/advances-in-the-diagnosis-and-management-of-neck-pain
#11
REVIEW
Steven P Cohen, W Michael Hooten
Neck pain imposes a considerable personal and socioeconomic burden-it is one of the top five chronic pain conditions in terms of prevalence and years lost to disability-yet it receives a fraction of the research funding given to low back pain. Although most acute episodes resolve spontaneously, more than a third of affected people still have low grade symptoms or recurrences more than one year later, with genetics and psychosocial factors being risk factors for persistence. Nearly half of people with chronic neck pain have mixed neuropathic-nociceptive symptoms or predominantly neuropathic symptoms...
August 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28807742/a-cost-utility-analysis-of-dynesys-dynamic-stabilization-versus-instrumented-fusion-for-the-treatment-of-degenerative-lumbar-spine-diseases
#12
Kan Liu, Wei Sun, Qiang Lu, Jiying Chen, Jiaguang Tang
BACKGROUND: Symptomatic chronic low back and leg pain resulting from lumbar spine degenerative disorders is highly prevalent in China, and for some patients, surgery is the final option for improvement. Several techniques for spinal non-fusion have been introduced to reduce the side-effects of fusion methods and hasten postoperative recovery. In this study, the authors have evaluated the cost-effectiveness of Dynesys posterior dynamic stabilization system (DY) compared with lumbar fusion techniques in the treatment of single-level degenerative lumbar spinal conditions...
August 11, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28804504/efficacy-of-auricular-acupressure-for-chronic-low-back-pain-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
REVIEW
Li-Hua Yang, Pei-Bei Duan, Qing-Mei Hou, Shi-Zheng Du, Jin-Fang Sun, Si-Juan Mei, Xiao-Qing Wang
OBJECTIVES: To identify the efficacy of auricular acupressure on pain and disability for chronic LBP by systematic review. METHODS: A search of randomized controlled trials was conducted in four English medical electronic databases and three Chinese databases. Two reviewers independently retrieved related studies, assessed the methodological quality, and extracted data with a standardized data form. Meta-analyses were performed using all time-points meta-analysis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28803704/effectiveness-of-graded-activity-versus-physiotherapy-in-patients-with-chronic-nonspecific-low-back-pain-midterm-follow-up-results-of-a-randomized-controlled-trial
#14
Maurício Oliveira Magalhães, Josielli Comachio, Paulo Henrique Ferreira, Evangelos Pappas, Amélia Pasqual Marques
BACKGROUND: Low back pain (LBP) is a major health and economic problem worldwide. Graded activity and physiotherapy are commonly used interventions for nonspecific low back pain. However, there is currently little evidence to support the use of one intervention over the other in the medium-term. OBJECTIVE: To compare the effectiveness of graded activity exercises to physiotherapy-based exercises at mid-term (three and six months' post intervention) in patients with chronic nonspecific LBP...
July 12, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28800302/the-effect-of-pain-severity-on-postural-stability-and-dynamic-limits-of-stability-in-chronic-low-back-pain
#15
Elsadat Saad Soliman, Tamer Mohamed Shousha, Mohamed Salaheldien Alayat
BACKGROUND: Deficits of dynamic balance in chronic low back pain patients have been reported by different studies in terms of impaired postural control. However, they excluded the degree of pain as a determinant affecting dynamic balance. OBJECTIVE: To evaluate the effect of pain intensity on dynamic balance control in terms of postural stability indices (PSIs) and limits of stability (LOS) in chronic LBP patients. METHODS: Sixty subjects (38 men, 22 women) participated in the current study, 45 patients with chronic LBP were selected randomly and served as the chronic LBP group while 15 healthy subjects served as the asymptomatic group (AS)...
July 31, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28798688/establishment-and-characterization-of-a-novel-rat-model-of-mechanical-low-back-pain-using-behavioral-pharmacologic-and-histologic-methods
#16
Arjun Muralidharan, Thomas S W Park, John T Mackie, Luiz G S Gimenez, Andy Kuo, Janet R Nicholson, Laura Corradini, Maree T Smith
Chronic low back pain (LBP), the leading cause of disability globally, is notoriously difficult to treat. Most rodent models of LBP mimic lumbar radicular pain rather than mechanical LBP. Here, we describe establishment of a new rat model of mechanical LBP that is devoid of a neuropathic component. Groups of adult male Sprague Dawley rats were anesthetized and their lumbar L4/L5 and L5/L6 intervertebral disks (IVDs) were punctured (0.5 mm outer diameter, 2mm-deep) 5 (LPB-5X), or 10 (LBP-10X) times per disk...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28797134/looking-beyond-the-intervertebral-disc-the-need-for-behavioral-assays-in-models-of-discogenic-pain
#17
REVIEW
Grace E Mosley, Thomas W Evashwick-Rogler, Alon Lai, James C Iatridis
Orthopedic research into chronic discogenic back pain has commonly focused on aging- and degeneration-related changes in intervertebral disc structure, biomechanics, and biology. However, the primary spine-related reason for physician office visits is pain. The ambiguous nature of the human condition of discogenic low back pain motivates the use of animal models to better understand the pathophysiology. Discogenic back pain models must consider both emergent behavioral changes following pain induction and changes in the nervous system that mediate such behavior...
August 10, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28796117/spouse-criticism-and-hostility-during-marital-interaction-effects-on-pain-intensity-and-behaviors-among-individuals-with-chronic-low-back-pain
#18
John W Burns, Kristina M Post, David A Smith, Laura S Porter, Asokumar Buvanendran, Anne Marie Fras, Francis J Keefe
Individuals with chronic pain may experience negative responses from spouse, family and friends. Responses such as overt criticism and hostility may be associated with worsening pain and function for chronic pain sufferers. We used a laboratory procedure to evaluate whether variability in spouse criticism/hostility exhibited toward chronic low back pain (CLBP) patients during a conflictual discussion predicted variability in patient pain and function during a subsequent pain-induction task. CLBP patients (n=71) and their spouses (n=71) participated in a 10-minute discussion followed by the patient undergoing a 10-minute structured pain behavior task (SPBT)...
August 8, 2017: Pain
https://www.readbyqxmd.com/read/28795462/a-cross-sectional-evaluation-of-the-prevalence-and-detection-of-predictors-of-polypharmacy-amongst-adult-in-spain
#19
Gracia Niclós, Teresa Olivar, Vicent Rodilla
OBJECTIVE: To investigate the association between polypharmacy and sociodemographic factors as well as health status, determinants of health and healthcare use, illness and use of prescribed medicines amongst adults in Spain. METHODS: Data from the 2009 European Health Interview Survey in Spain which included 22 188 subjects were used. Polypharmacy was defined as the use of five or more prescribed medicines. The association between polypharmacy and several variables was assessed by means of bivariate analysis and logistic regression analysis (adjusted by age and gender)...
August 10, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28795014/evaluation-and-management-of-lower-back-pain-in-young-athletes
#20
REVIEW
Dilip R Patel, Elizabeth Kinsella
Lower back pain in young athletes is a common problem. The prevalence of back pain from different causes in adolescent age group is between 20% and 30%. However, the incidence of low back pain in young athletes varies widely in different sports. Overuse injuries are the most common cause of low back pain in young athletes. In case of overuse injuries, the cause and effect relationship between back pain and specific condition is often difficult to establish. In adolescent athletes, the most common underlying identified cause of low back pain is lumbar spondylolysis...
July 2017: Translational pediatrics
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