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https://www.readbyqxmd.com/read/28077414/implementation-of-a-consumer-focused-ehealth-intervention-for-people-with-moderate-to-high-cardiovascular-disease-risk-protocol-for-a-mixed-methods-process-evaluation
#1
Genevieve M Coorey, Lis Neubeck, Timothy Usherwood, David Peiris, Sharon Parker, Annie Y S Lau, Clara Chow, Kathryn Panaretto, Mark Harris, Nicholas Zwar, Julie Redfern
INTRODUCTION: Technology-mediated strategies have potential to engage patients in modifying unhealthy behaviour and improving medication adherence to reduce morbidity and mortality from cardiovascular disease (CVD). Furthermore, electronic tools offer a medium by which consumers can more actively navigate personal healthcare information. Understanding how, why and among whom such strategies have an effect can help determine the requirements for implementing them at a scale. This paper aims to detail a process evaluation that will (1) assess implementation fidelity of a multicomponent eHealth intervention; (2) determine its effective features; (3) explore contextual factors influencing and maintaining user engagement; and (4) describe barriers, facilitators, preferences and acceptability of such interventions...
January 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28076528/the-brief-life-of-norplant%C3%A2-in-brazil-controversies-and-reassemblages-between-science-society-and-state
#2
Ana Cristina de Lima Pimentel, Cláudia Bonan Jannotti, Paula Gaudenzi, Luiz Antonio da Silva Teixeira
Norplant® is the brand name of the world's first registered subdermal hormonal contraceptive implant, developed by the laboratories of the Population Council, an international organisation working in the area of fertility and population growth. The article revisits the trajectory of this contraceptive in Brazil from its arrival through clinical trials to its eventual ban in 1986 by the Brazilian regulatory agency responsible for approving medications at the time. Its circulation generated controversies related to research practices, side effects and political uses of the drug as a birth control method...
January 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28072747/the-clinical-characteristics-and-short-term-prognosis-in-elderly-patients-with-guillain-barr%C3%A3-syndrome
#3
Bing Zhang, Xiujuan Wu, Donghui Shen, Ting Li, Chunrong Li, Mei Mao, Hong-Liang Zhang, Kangding Liu
To investigate the clinical characteristics and short-term prognosis of elderly patients with Guillain-Barré syndrome (GBS).We retrospectively analyzed the clinical data of adult GBS. According to the age, the enrolled subjects were divided into 2 groups, that is, patients ≥60 years (elderly group) and those aged 18 to 59 years (nonelderly group). The clinical characteristics and short-term prognosis of the patients in the 2 groups were compared.In total, 535 patients were enrolled. There were 67 patients fell into the elderly group with a mean age of 69 years old; while 468 patients fell into the nonelderly group with a mean age of 39 years old...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28070773/challenges-and-opportunities-building-a-relationship-between-a-department-of-biomedical-engineering-and-a-medical-school
#4
EDITORIAL
Steven C George, M Elizabeth Meyerand
A department of biomedical engineering can significantly enhance the impact of their research and training programs if a productive relationship with a medical school can be established. In order to develop such a relationship, significant hurdles must be overcome. This editorial summarizes some of the major challenges and opportunities for a department of biomedical engineering as they seek to build or enhance a relationship with a medical school. The ideas were formulated by engaging the collective wisdom from the Council of Chairs of the biomedical engineering departments...
January 9, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28067712/muscle-weakness-and-5-year-survival-in-acute-respiratory-distress-syndrome-survivors
#5
Victor D Dinglas, Lisa Aronson Friedman, Elizabeth Colantuoni, Pedro A Mendez-Tellez, Carl B Shanholtz, Nancy D Ciesla, Peter J Pronovost, Dale M Needham
OBJECTIVES: To longitudinally evaluate the association of post-ICU muscle weakness and associated trajectories of weakness over time with 5-year survival. DESIGN: Longitudinal prospective cohort study over 5 years of follow-up. SETTING: Thirteen ICUs in four hospitals in Baltimore, MD. PATIENTS: One hundred fifty-six acute respiratory distress syndrome survivors. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Strength was evaluated with standardized manual muscle testing using the Medical Research Council sum score (range, 0-60; higher is better), with post-ICU weakness defined as sum score less than 48...
January 6, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28063815/effect-of-immediate-initiation-of-antiretroviral-therapy-on-risk-of-severe-bacterial-infections-in-hiv-positive-people-with-cd4-cell-counts-of-more-than-500-cells-per-%C3%AE-l-secondary-outcome-results-from-a-randomised-controlled-trial
#6
Jemma O'Connor, Michael J Vjecha, Andrew N Phillips, Brian Angus, David Cooper, Beatriz Grinsztejn, Gustavo Lopardo, Satyajit Das, Robin Wood, Aimee Wilkin, Hartwig Klinker, Pacharee Kantipong, Karin L Klingman, David Jilich, Elbushra Herieka, Eileen Denning, Ibrahim Abubakar, Fred Gordin, Jens D Lundgren
BACKGROUND: The effects of antiretroviral therapy on risk of severe bacterial infections in people with high CD4 cell counts have not been well described. In this study, we aimed to quantify the effects of immediate versus deferred ART on the risk of severe bacterial infection in people with high CD4 cell counts in a preplanned analysis of the START trial. METHODS: The START trial was a randomised controlled trial in ART-naive HIV-positive patients with CD4 cell count of more than 500 cells per μL assigned to immediate ART or deferral until their CD4 cell counts were lower than 350 cells per μL...
January 4, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28063795/effect-of-new-tuberculosis-diagnostic-technologies-on-community-based-intensified-case-finding-a-multicentre-randomised-controlled-trial
#7
Gregory L Calligaro, Lynn S Zijenah, Jonathan G Peter, Grant Theron, Virginia Buser, Ruth McNerney, Wilbert Bara, Tsitsi Bandason, Ureshnie Govender, Michele Tomasicchio, Liezel Smith, Bongani M Mayosi, Keertan Dheda
BACKGROUND: Inadequate case detection results in high levels of undiagnosed tuberculosis in sub-Saharan Africa. Data for the effect of new diagnostic tools when used for community-based intensified case finding are not available, so we investigated whether the use of sputum Xpert-MTB/RIF and the Determine TB LAM urine test in two African communities could be effective. METHODS: In a pragmatic, randomised, parallel-group trial with individual randomisation stratified by country, we compared sputum Xpert-MTB/RIF, and if HIV-infected, the Determine TB LAM urine test (novel diagnostic group), with laboratory-based sputum smear microscopy (routine diagnostic group) for intensified case finding in communities with high tuberculosis and HIV prevalence in Cape Town, South Africa, and Harare, Zimbabwe...
January 4, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28057898/a-retrospective-study-of-degenerative-mitral-valve-disease-in-small-breed-dogs-survival-and-prognostic-variables
#8
Hyun-Tae Kim, Sei-Myoung Han, Woo-Jin Song, Boeun Kim, Mincheol Choi, Junghee Yoon, Hwa-Young Youn
Small-breed (n= 168 dogs; weight < 15 kg) diagnosed with MMVD based on a routine clinical examination, radiology, an electrocardiogram, and echocardiography at the Seoul National University Veterinary Medical Teaching Hospital were included. The survival periods were ascertained and a significant difference was observed in the survival rates between the International Small Animal Cardiac Health Council classes. The mean follow-up period was 14.3 ± 12.1 months. Univariate analysis revealed that dyspnea, pulmonary edema, and vertebral heart score were significantly associated with the survival times (P < 0...
January 4, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28056765/comparison-of-dna-quantification-methodology-used-in-the-dna-extraction-protocol-for-the-uk-biobank-cohort
#9
Samantha Welsh, Tim Peakman, Simon Sheard, Rachael Almond
BACKGROUND: UK Biobank is a large prospective cohort study in the UK established by the Medical Research Council (MRC) and the Wellcome Trust to enable approved researchers to investigate the role of genetic factors, environmental exposures and lifestyle in the causes of major diseases of late and middle age. A wide range of phenotypic data has been collected at recruitment and has recently been enhanced by the UK Biobank Genotyping Project. All UK Biobank participants (500,000) have been genotyped on either the UK Biobank Axiom® Array or the Affymetrix UK BiLEVE Axiom® Array and the workflow for preparing samples for genotyping is described...
January 5, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28056512/palliative-care-exposure-in-internal-medicine-residency-education
#10
Asher Edwards, Samuel Nam
As the baby boomer generation ages, the need for palliative care services will be paramount and yet training for palliative care physicians is currently inadequate to meet the current palliative care needs. Nonspecialty-trained physicians will need to supplement the gap between supply and demand. Yet, no uniform guidelines exist for the training of internal medicine residents in palliative care. To our knowledge, no systematic study has been performed to evaluate how internal medicine residencies currently integrate palliative care into their training...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28053520/psychometric-properties-of-the-physical-activity-scale-for-the-elderly-in-chinese-patients-with-copd
#11
Yan-Xia Tao, Lan Wang, Xiao-Yan Dong, Hong Zheng, Ya-Shu Zheng, Xing-Yue Tang, Yue Zhao, Qing Zhang
BACKGROUND: For patients with COPD, physical activity (PA) is recommended as the core component of pulmonary rehabilitation, but there is lack of a validated questionnaire for assessing the PA effectively. AIM: To evaluate the reliability and validity of the Chinese version of Physical Activity Scale for the Elderly (PASE-C) in patients with COPD. METHODS: A cross-sectional study was conducted with 167 outpatients aged 60 years or older with COPD...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28052572/an-undergraduate-otolaryngology-curriculum-comparison-in-the-united-kingdom-using-a-curriculum-evaluation-framework
#12
R A Steven, G J Mires, S K W Lloyd, S McAleer
OBJECTIVE: 1.To compare undergraduate Otolaryngology curricula in the United Kingdom. 2.To develop a tool which would allow undergraduate specialty curricula to be compared. DESIGN: Development of a Curriculum Evaluation Framework and survey. SETTING: UK medical schools. PARTICIPANTS: Otolaryngology curricula were requested from all 32 UK medical schools who award a primary medical qualification. 19 curricula were received and examined...
January 4, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28051967/introducing-a-novel-applicant-ranking-tool-to-predict-future-resident-performance-a-pilot-study
#13
Sarah N Bowe, Erik K Weitzel, William N Hannah, Brian M Fitzgerald, Gregory P Kraus, Christopher J Nagy, Stephen A Harrison
The purposes of this study are to (1) introduce our novel Applicant Ranking Tool that aligns with the Accreditation Council for Graduate Medical Education competencies and (2) share our preliminary results comparing applicant rank to current performance. After a thorough literature review and multiple roundtable discussions, an Applicant Ranking Tool was created. Feasibility, satisfaction, and critiques were discussed via open feedback session. Inter-rater reliability was assessed using weighted kappa statistic (κ) and Kendall coefficient of concordance (W)...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28051002/medical-biochemistry-is-it-time-to-change-the-teaching-style
#14
Jeeji Palocaren, Lekha S Pillai, T M Celine
BACKGROUND: The Medical Council of India (MCI) recommendations on medical education suggest a shift from didactic lectures to more interactive lectures. This study assessed the effectiveness of different pedagogical methods in biochemistry and the perceptions of students and teachers about the shift from didactic to interactive lectures. METHODS: An interventional crossover study was done with the topic divided into three biochemical modules and one clinical module...
July 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/28050392/paediatric-prescription-analysis-in-a-primary-health-care-institution
#15
Jinish Jose, Denny Devassykutty
INTRODUCTION: Paediatric prescription analysis was done by vari-ous studies in tertiary care centers but not much published data, at primary care level. The Medical Council of India introduced new prescription format and also antibiotic stewardship program was launched by Government of Kerala in the year 2015. So in these contexts this study was conducted. AIM: To analyse the patterns of prescriptions and drug dis-pensing in pediatric patients using WHO core drug use indicators and parameters in the prescription format prescribed by Medical Council of India...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050255/the-role-of-general-practitioners-in-medical-school-admission-interview-panels-in-the-uk-2012-2014-a-national-survey
#16
Mohammed Ahmed Rashid, John Benson
OBJECTIVE: Recent primary care workforce pressures in the UK have prompted national reviews. Recommendations to increase the proportion of medical students entering general practice have led to interest in the role of medical schools in career choices. This study sought to identify the career backgrounds of admissions leads at UK medical schools and the proportion of general practitioners on admission interview panels. DESIGN: A national survey using a proforma circulated to all UK medical school admission leads via the Medical Schools Council...
July 2016: JRSM Open
https://www.readbyqxmd.com/read/28048838/su-f-i-36-in-utero-dose-measurements-within-postmortem-subjects-for-estimating-fetal-doses-in-pregnant-patients-examined-with-pulmonary-embolism-trauma-and-appendicitis-ct
#17
I Lipnharski, N Quails, C Carranza, N Correa, S Bidari, M Bickelhaup, L Rill, M Arreola
PURPOSE: The imaging of pregnant patients is medically necessary in certain clinical situations. The purpose of this work was to directly measure uterine doses in a cadaver scanned with CT protocols commonly performed on pregnant patients in order to estimate fetal dose and assess potential risk. METHOD: One postmortem subject was scanned on a 320-slice CT scanner with standard pulmonary embolism, trauma, and appendicitis protocols. All protocols were performed with the scan parameters and ranges currently used in clinical practice...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048663/tu-fg-207a-05-winners-1-2-3-and-q-a
#18
C McCollough
: Peer-reviewed journals and conference proceedings publish hundreds of papers that describe new medical imaging algorithms, including, for example, techniques for computer-aided diagnosis or characterization, segmentation, image registration, image reconstruction, and radiomics. It is difficult, if not impossible, to fairly compare the performance of these algorithms as investigators must either use different data sets, or if using the same data, use different implementations of competing algorithms...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048651/tu-fg-207a-03-overview-of-ct-reconstruction-and-denoising-strategies
#19
N Pelc
: Peer-reviewed journals and conference proceedings publish hundreds of papers that describe new medical imaging algorithms, including, for example, techniques for computer-aided diagnosis or characterization, segmentation, image registration, image reconstruction, and radiomics. It is difficult, if not impossible, to fairly compare the performance of these algorithms as investigators must either use different data sets, or if using the same data, use different implementations of competing algorithms...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048646/tu-ab-brc-07-efficiency-of-an-iaea-phase-space-source-for-a-low-energy-x-ray-tube-using-egs
#20
Pgf Watson, M A Renaud, J Seuntjens
PURPOSE: To extend the capability of the EGSnrc C++ class library (egs++) to write and read IAEA phase-space files as a particle source, and to assess the relative efficiency gain in dose calculation using an IAEA phase-space source for modelling a miniature low energy x-ray source. METHODS: We created a new ausgab object to score particles exiting a user-defined geometry and write them to an IAEA phase-space file. A new particle source was created to read from IAEA phase-space data...
June 2016: Medical Physics
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