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https://www.readbyqxmd.com/read/29241089/association-of-psychosis-with-antiphospholipid-antibody-syndrome-a-systematic-review-of-clinical-studies
#1
Asma Hallab, Sadiq Naveed, Ahmed Altibi, Mariam Abdelkhalek, Huyen Thi Ngo, Thao Phuong Le, Kenji Hirayama, Nguyen Tien Huy
OBJECTIVE: In this systematic review, we reviewed the association between Antiphospholipid antibody syndrome (APS) and psychosis and focused on the prevalence, clinical presentation, immunologic and neurological workup, treatment options, and clinical outcomes. METHODOLOGY: We performed this systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)'s guidelines. We searched eight databases for potential articles and manually searched references and relevant articles of included studies...
November 16, 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29240944/a-right-to-access-to-emergency-health-care-the-european-court-of-human-rights-pushes-the-envelope
#2
Aleydis Nissen
This article argues that the European Court of Human Rights (ECtHR) seems to have recently acknowledged that there is a right to access to emergency health care in the member states of the Council of Europe. The Chamber of the ECtHR found that a state's failure to design a regulatory framework that guarantees access to health care in emergency situations violates the substantial limb of Article 2 European Convention on Human Rights (ECHR) that protects the right to life. It is argued that the newly established requirements seem to be reasonable but that there seem to be no sufficient safeguards to ensure that the ECtHR does not substitute its own assessment for that of medical professionals...
December 11, 2017: Medical Law Review
https://www.readbyqxmd.com/read/29239885/the-present-state-of-neurointensivist-training-in-the-united-states-a-comparison-to-other-critical-care-training-programs
#3
Evie G Marcolini, David B Seder, Jordan B Bonomo, Thomas P Bleck, J Claude Hemphill, Lori Shutter, Fred Rincon, Shelly D Timmons, Paul Nyquist
OBJECTIVE: This manuscript describes the state of neurocritical care fellowship training, compares its written standards to those of other critical care fellowship programs, and discusses how programmatic oversight by the United Council for Neurological Subspecialties should evolve to meet American College of Graduate Medical Education standards. This review is a work product of the Society of Critical Care Medicine Neuroscience section and was reviewed and approved by the Council of the Society of Critical Care Medicine...
December 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29238608/study-protocol-for-enhancing-parenting-in-cancer-epic-development-and-evaluation-of-a-brief-psycho-educational-intervention-to-support-parents-with-cancer-who-have-young-children
#4
Lesley Stafford, Michelle Sinclair, Jane Turner, Louise Newman, Claire Wakefield, Mei Krishnasamy, G Bruce Mann, Leslie Gilham, Kylie Mason, Paula Rauch, Julia Cannell, Penelope Schofield
Background: Parents with cancer have high rates of psychological morbidity, and their children are at risk of poor psychosocial outcomes, particularly in the context of parental distress and poor family communication. Parents express concerns about the impact of cancer on their children and report a lack of professional guidance in meeting their children's needs. Few parenting interventions exist and current interventions have extensive infrastructure demands making them unsuitable for routine use in most health settings...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29238506/comparison-of-the-effect-of-topiramate-versus-gabapentin-on-neuropathic-pain-in-patients-with-polyneuropathy-a-randomized-clinical-trial
#5
Surena Nazarbaghi, Mohammad Reza Amiri-Nikpour, Aynaz Foroughi Eghbal, Rohollah Valizadeh
Background: Neuropathic pain is one of the most common complaints of neurologic clinics. Neuropathic pain is common and important and has inappropriate complications, and despite their importance, there is no effective treatment for them. Objective: Because of the importance of neuropathic pain and safe and effective treatment, in this study, we determined the effect of topiramate versus gabapentin in patients with neuropathic pain. Methods: In this randomized clinical trial, 30 patients with pain attributed to neuropathy who had at least one month of neuropathic pain in one area, were randomized to receive either gabapentin, titrated from 300 mg/day to a maximum of 900 mg/day or topiramate, titrated from 50 mg/day to a maximum of 100 mg/day after a 4-week period in the neurology clinic of Imam Khomeini Hospital of Urmia city, Iran in 2015...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238186/severe-copd-cases-from-korea-poland-and-usa-have-substantial-differences-in-respiratory-symptoms-and-other-respiratory-illnesses
#6
Woo Jin Kim, Jae-Joon Yim, Deog Kyeom Kim, Myung Goo Lee, Anne L Fuhlbrigge, Pawel Sliwinski, Iwona Hawrylkiewicz, Emily S Wan, Michael H Cho, Edwin K Silverman
Purpose: Chronic obstructive pulmonary disease (COPD), characterized by irreversible airflow obstruction, is a major cause of morbidity and mortality worldwide. However, geographic differences in the clinical characteristics of severe COPD patients have not been widely studied. Methods: We recruited a total of 828 severe COPD cases from three continents. Subjects in Poland were enrolled by the Institute of Tuberculosis and Lung Diseases in Warsaw; subjects in Korea participated at several university hospitals in Korea; and subjects in USA were enrolled at two clinics affiliated with academic medical centers...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29238182/adherence-to-a-copd-treatment-guideline-among-patients-in-hong-kong
#7
Ka Pang Chan, Fanny Ws Ko, Hok Sum Chan, Mo Lin Wong, Thomas Yw Mok, Kah Lin Choo, David Sc Hui
Background: This study aimed to assess the adherence rate of pharmacological treatment to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline published in 2011 and the prevalence of comorbidities among patients with COPD in Hong Kong (HK). Methods: Patients were recruited from five tertiary respiratory centers and followed up for 12 months. Data on baseline physiological, spirometric parameters, use of COPD medications and coexisting comorbidities were collected...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29237929/contralateral-c7-nerve-root-transfer-for-function-recovery-in-adults-a-meta-analysis
#8
Wen-Jun Li, Li-Yue He, Shan-Lin Chen, Yan-Wei Lyu, Shu-Feng Wang, Yang Yong, Wen Tian, Guang-Lei Tian, Yu-Dong Gu
BACKGROUND: Root avulsion to all 5 roots of the brachial plexus is a common presentation and keeps a major reconstructive challenge. The contralateral C7 (CC7) nerve transfer has been used in treating brachial plexus avulsion injury (BPAI) since 1986. However, the effectiveness of the procedure remains a subject of controversy. The aim of this meta-analysis was to study surgical outcomes regarding motor and sensory recovery after CC7 nerve transfer. METHODS: Chinese or English (i...
December 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29237078/determinants-of-peripheral-muscle-strength-and-activity-in-daily-life-in-people-with-bronchiectasis
#9
Anderson Alves de Camargo, Jacqueline C Boldorini, Anne E Holland, Rejane A Silva de Castro, Fernanda de Cordoba Lanza, Rodrigo A Athanazio, Samia Z Rached, Regina Carvalho-Pinto, Alberto Cukier, Rafael Stelmach, Simone Dal Corso
Background: Bronchiectasis is characterized by a progressive structural lung damage, recurrent infections and chronic inflammation which compromise the exertion tolerance, and may have an impact on skeletal muscle function and physical function. Objective: The purpose of this study was to compare peripheral muscle strength, exercise capacity, and physical activity in daily life between participants with bronchiectasis and controls and to investigate the determinants of the peripheral muscle strength and physical activity in daily life in bronchiectasis...
December 9, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29237021/human-specific-subcellular-compartmentalization-of-p-element-induced-wimpy-testis-like-piwil-granules-during-germ-cell-development-and-spermatogenesis
#10
Maria Gomes Fernandes, Nannan He, Fang Wang, Liesbeth Van Iperen, Cristina Eguizabal, Roberto Matorras, Bernard A J Roelen, Susana M Chuva De Sousa Lopes
STUDY QUESTION: What is the dynamics of expression of P-element induced wimpy testis-like (PIWIL) proteins in the germline during human fetal development and spermatogenesis? SUMMARY ANSWER: PIWIL1, PIWIL2, PIWIL3 and PIWIL4 were expressed in a sex-specific fashion in human germ cells (GC) during development and adulthood. PIWILs showed a mutually exclusive pattern of subcellular localization. PIWILs were present in the intermitochondrial cement and a single large granule in meiotic GC and their expression was different from that observed in mice, highlighting species-differences...
December 11, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29235405/mapping-the-balint-groups-to-the-accreditation-council-for-graduate-medical-education-family-medicine-competencies
#11
Albert Lichtenstein, Jumana Antoun, Chris Rule, Katherine Knowlton, Jeffrey Sternlieb
Introduction Balint group discussions provide learning opportunities for many of the competencies and milestones put forward by the Accreditation Council for Graduate Medical Education. The current literature is mixed concerning the effect of Balint groups on communication skills and professionalism. Aim To map the content of the Balint discussion to the competencies and milestones put forward by the Accreditation Council for Graduate Medical Education. METHODOLOGY: A group who were both experts in Balint and members of the clinical competency committee of residency programs rated narratives that summarized Balint group discussions...
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29233422/implementation-of-a-virtual-dispensing-simulator-to-support-us-pharmacy-education
#12
Marcus Ferrone, Clark Kebodeaux, Jill Fitzgerald, Lisa Holle
INTRODUCTION: A key element for pharmacy practice defined by the Accreditation Council for Pharmacy Education (ACPE) is medication use systems management. A web-based community pharmacy simulation originally created for Australian pharmacy students was adapted for pharmacy students in the United States (US). The objective of this study was to collaboratively adapt an existing international simulation program for utility in the US and measure student perceptions of a web-based community pharmacy simulation program in three US schools of pharmacy...
July 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233371/experience-with-the-script-concordance-test-to-develop-clinical-reasoning-skills-in-pharmacy-students
#13
Kylee A Funk, Claire Kolar, Sarah K Schweiss, Jeffrey M Tingen, Kristin K Janke
BACKGROUND: The script concordance test (SCT) is used to assess clinical reasoning and was originally developed for medical learners. The Accreditation Council for Pharmacy Education (ACPE) endorses the need for pharmacy students to develop clinical reasoning skills, but there is little documentation of use of the SCT for pharmacy learners. EDUCATIONAL ACTIVITY: A script concordance test activity was designed for a diabetes and metabolic syndrome pharmacotherapy course...
November 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29232980/effectiveness-of-aquatic-versus-land-physiotherapy-in-the-treatment-of-peripheral-neuropathies-a-randomized-controlled-trial
#14
Ilaria Zivi, Sara Maffia, Vanessa Ferrari, Alessio Zarucchi, Katia Molatore, Roberto Maestri, Giuseppe Frazzitta
OBJECTIVE: To compare the effects on gait and balance of aquatic physiotherapy versus on-land training, in the context of an inpatient rehabilitation treatment tailored for peripheral neuropathies. DESIGN: Parallel-group, single-center, single-blind randomized controlled trial. SUBJECTS AND SETTING: Consecutive patients affected by peripheral neuropathy admitted in our Neuro-Rehabilitation Unit. INTERVENTIONS: Patients received a four-week rehabilitation program composed by daily sessions of conventional physiotherapy and three sessions/week of specific treatment (aquatic vs...
December 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29229088/correlation-of-serum-vascular-adhesion-protein-1-with-airflow-limitation-and-quality-of-life-in-stable-chronic-obstructive-pulmonary-disease
#15
Mojtaba Amani, Naiemeh Ghadimi, Mohammad Reza Aslani, Hassan Ghobadi
OBJECTIVE: The serum vascular adhesion protein-1 (VAP-1) level increases in chronic inflammatory diseases. The present study aimed to examine serum VAP-1 level in patients with stable chronic obstructive pulmonary disease (COPD) and the correlation of this marker with airflow limitation and health-related quality of life using the COPD Assessment Test (CAT). MATERIALS AND METHODS: We measured serum VAP-1 level in 43 patients with stable COPD and 30 control subjects and compared them with airflow limitation according to the COPD stage in the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria, peripheral O2 saturation (SpO2), and CAT score...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29228887/can-whole-body-vibration-exercises-affect-growth-hormone-concentration-a-systematic-review
#16
Laisa Liane Paineiras-Domingos, Danúbia da Cunha de Sá-Caputo, Eloá Moreira-Marconi, Danielle Soares Morel, Carla da Fontoura Dionello, Cintia Renata Sousa-Gonçalves, Éric Heleno Freire Ferreira Frederico, Pedro Jesus Marín, Sofia Tamini, Alessandro Sartorio, Mario Bernardo-Filho
Whole body vibration (WBV) has been recognized as an effective alternative exercise modality to resistance exercise for its ability in enhancing force and power, generating capacity in skeletal muscle, increasing bone mass and improving cardiovascular function. Since the effect of WBV exercises on growth hormone (GH) levels has been never compared and discussed, the aim of this study was to review systematically the literature to verify the WBV effects on GH concentration. By using PubMed, Scopus and PEDRo databases with the keywords 'growth hormone' or GH and 'whole body vibration' or WBV, we found and analysed 12 papers (182 subjects recruited), verifying their level of evidence (National Health and Medical Research Council hierarchy of evidence) and the methodological quality (PEDRo scale)...
October 2017: Growth Factors
https://www.readbyqxmd.com/read/29223767/evaluation-of-a-national-pediatric-subinternship-curriculum-implemented-through-individual-learning-plans
#17
Linda R Tewksbury, Cristina Carter, Lyuba Konopasek, Sandra M Sanguino, Janice L Hanson
OBJECTIVE: The Council on Medical Student Education in Pediatrics and Association of Pediatric Program Directors developed a Pediatric Subinternship (CAPS) Curriculum for use with an individualized learning plan (ILP). The authors determined which learning objectives (LOs) pediatric subinterns selected when provided the CAPS Curriculum, summarized students' self-reported progress, and determined feasibility of ILPs in subinternship. METHODS: Students from 10 medical schools completed a standardized ILP during pediatric subinternship...
December 6, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/29220738/increasing-value-and-reducing-waste-by-optimizing-the-development-of-complex-interventions-enriching-the-development-phase-of-the-medical-research-council-mrc-framework
#18
Nienke Bleijenberg, Janneke M de Man-van Ginkel, Jaap C A Trappenburg, Roelof G A Ettema, Carolien G Sino, Noor Heim, Thóra B Hafsteindóttir, David A Richards, Marieke J Schuurmans
BACKGROUND: In recent years there has been much emphasis on 'research waste' caused by poor question selection, insufficient attention to previous research results, and avoidable weakness in research design, conduct and analysis. Little attention has been paid to the effect of inadequate development of interventions before proceeding to a full clinical trial. OBJECTIVE: We therefore propose to enrich the development phase of the MRC Framework by adding crucial elements to improve the likelihood of success and enhance the fit with clinical practice METHODS: Based on existing intervention development guidance and synthesis, a comprehensive iterative intervention development approach is proposed...
December 5, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29219757/spinal-accessory-nerve-to-triceps-muscle-transfer-using-long-autologous-nerve-grafts-for-recovery-of-elbow-extension-in-traumatic-brachial-plexus-injuries
#19
Liselotte F Bulstra, Nadia Rbia, Michelle F Kircher, Robert J Spinner, Allen T Bishop, Alexander Y Shin
OBJECTIVE Reconstructive options for brachial plexus lesions continue to expand and improve. The purpose of this study was to evaluate the prevalence and quality of restored elbow extension in patients with brachial plexus injuries who underwent transfer of the spinal accessory nerve to the motor branch of the radial nerve to the long head of the triceps muscle with an intervening autologous nerve graft and to identify patient and injury factors that influence functional triceps outcome. METHODS A total of 42 patients were included in this retrospective review...
December 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29218359/-significance-of-the-doctorate-in-scientific-medical-education
#20
Matthias Frosch
According to European and German law, the medical education of physicians must take place in a scientific degree program at a university or under the supervision of a university. To keep up the ideal of a scientific degree program, various organizations and associations, such as the German Research Foundation, the German Council of Science and Humanities and the German Medical Faculty Association, see the need for an even stronger anchoring of academic learning content in the course of study. Traditionally, a scientific project, which is carried out during the studies, provides the basis for the Doctor of Medicine (Dr...
December 7, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
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