keyword
https://read.qxmd.com/read/38627560/transparent-medical-image-ai-via-an-image-text-foundation-model-grounded-in-medical-literature
#1
JOURNAL ARTICLE
Chanwoo Kim, Soham U Gadgil, Alex J DeGrave, Jesutofunmi A Omiye, Zhuo Ran Cai, Roxana Daneshjou, Su-In Lee
Building trustworthy and transparent image-based medical artificial intelligence (AI) systems requires the ability to interrogate data and models at all stages of the development pipeline, from training models to post-deployment monitoring. Ideally, the data and associated AI systems could be described using terms already familiar to physicians, but this requires medical datasets densely annotated with semantically meaningful concepts. In the present study, we present a foundation model approach, named MONET (medical concept retriever), which learns how to connect medical images with text and densely scores images on concept presence to enable important tasks in medical AI development and deployment such as data auditing, model auditing and model interpretation...
April 16, 2024: Nature Medicine
https://read.qxmd.com/read/38624009/pet-ct-vs-brain-mri-for-the-detection-of-cerebral-metastases-of-melanoma-a-5-year-retrospective-study
#2
JOURNAL ARTICLE
Lisa Tutic-Sorrentino, Simone Cazzaniga, Laurence Feldmeyer, Michael Benzaquen
BACKGROUND: Melanoma patients present a high risk of developing extra cutaneous metastases. PET-CT is one of the preferred examinations for the staging of oncological patients. It is not the method of choice to detect brain metastases, but this technique has shown significant improvement and allows the detection of some of them, although it is unclear how it performs compared to the MRI, the current gold standard for diagnosing brain metastases. OBJECTIVE: To compare the accuracy of PET-CT and cerebral MRI to detect brain metastases in melanoma patients...
April 16, 2024: Clinical and Experimental Dermatology
https://read.qxmd.com/read/38606617/gender-equity-in-academic-dermatology-problems-aplenty-yet%C3%A2-paths-ahead
#3
REVIEW
Sophie Walter, Dedee F Murrell
Efforts to achieve gender equity of health professionals should be a priority in all fields of medicine, including academic dermatology. This review aimed, first, to summarize available evidence about the status of gender equity in various domains of academic dermatology-headship positions, salary, editor and editorial board appointments, publications, conference presentations, receipt of research grants and academic prizes-second, to identify challenges to achieving gender equity and, third, to articulate the components of a multifaceted strategy for gender parity...
April 12, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
https://read.qxmd.com/read/38572264/is-beauty-worth-the-risk-self-confidence-is-the-key-motivating-factor-driving-tanning-bed-use-among-undergraduate-students-at-south-dakota-universities
#4
JOURNAL ARTICLE
Jazmin Newton, Lauren Ochoa, Aly Reinschmidt, John Vassar, Allen Wellman, Minga Vargas, DenYelle Kenyon, Marcus Frohm
BACKGROUND: Exposure to ultraviolet radiation is a leading risk factor for developing all types of skin cancer. In the United States, an estimated 7.8 million young adults engage in indoor tanning. OBJECTIVE: Here, it is hypothesized that certain populations of students at undergraduate universities, namely sorority members, have a greater frequency of tanning bed usage than other groups of students and that regardless of sorority status, the most important motivating factor will be the intent to enhance one's appearance...
June 2024: International Journal of Women's Dermatology
https://read.qxmd.com/read/38549184/dermatology-residents-perspectives-on-virtual-dermatopathology-education
#5
JOURNAL ARTICLE
Tram B Ngo, Wei Niu, Zhide Fang, Logan Gold
BACKGROUND: Dermatopathology education accounts for 30% of U.S. dermatology residency training. The COVID-19 pandemic expedited the implementation of virtual dermatopathology in place of traditional microscopy for resident education. This study examined U.S. dermatology residents' perceptions of virtual dermatopathology, as research in this area is lacking. METHODS: An anonymous, confidential, institutional review board-approved survey was electronically distributed to U...
March 28, 2024: Journal of Cutaneous Pathology
https://read.qxmd.com/read/38546714/social-media-use-in-dermatology-in-turkey-challenges-and-tips-for-patient-health
#6
JOURNAL ARTICLE
Ayse Serap Karadag, Basak Kandi, Berna Sanlı, Hande Ulusal, Hasan Basusta, Seray Sener, Sinem Calıka
Social media has established its place in our daily lives, especially with the advent of the COVID-19 pandemic. It has become the leading source of information for dermatological literacy on various topics, ranging from skin diseases to everyday skincare and cosmetic purposes in the present digital era. Accumulated evidence indicates that accurate medical content constitutes only a tiny fraction of the exponentially growing dermatological information on digital platforms, highlighting an unmet patient need for access to evidence-based information on social media...
March 28, 2024: JMIR dermatology
https://read.qxmd.com/read/38538768/screening-for-body-dysmorphic-disorder-in-plastic-surgery-patients
#7
JOURNAL ARTICLE
David R Thomson, Natasha E V Thomson, Graeme Southwick
INTRODUCTION: The Australian medical board, the Australian Health Practitioner Regulation Agency (AHPRA) has recently introduced new regulations mandating providers of cosmetic surgery undertake a clinical screen for body dysmorphic disorder (BDD) in all potential cosmetic surgery patients. The assessment must be conducted by the surgeon using a validated psychological screening tool. The aims of this paper are to discuss the key clinical characteristics of BDD before reviewing currently validated screening tools that would meet this new regulatory requirement, and which may be most applicable to a busy plastic surgery practice...
March 27, 2024: Aesthetic Plastic Surgery
https://read.qxmd.com/read/38521873/inconsistent-associations-between-risk-factor-profiles-and-adjuvant-radiation-therapy-art-treatment-in-patients-with-cutaneous-squamous-cell-carcinoma-and-utility-of-the-40-gene-expression-profile-to-refine-art-guidance
#8
JOURNAL ARTICLE
Brent R Moody, Aaron S Farberg, Ally-Khan Somani, Walton A Taylor
INTRODUCTION: National Comprehensive Cancer Network (NCCN) recommendations for adjuvant radiation therapy (ART) use are similar for High Risk and Very High Risk cutaneous squamous cell carcinoma (cSCC) with negative post-surgical margins. Although studies report reductions in disease progression following ART treatment, ART use is likely inconsistent when guided by available risk factors. This study evaluated the association of ART with clinical risk factors in ART-treated and untreated patients and showed the clinical utility of the 40-gene expression profile (40-GEP) for guiding ART...
March 23, 2024: Dermatology and Therapy
https://read.qxmd.com/read/38507330/can-dermatologists-reach-their-full-potential-in-teledermatology-a-validation-study-of-diagnostic-performance%C3%A2-of-skin-diseases-in-live-video-conferencing%C3%A2-teledermatology
#9
JOURNAL ARTICLE
Atsushi Fujimoto, Ryota Hayashi, Seitaro Iguchi, Riichiro Abe
The diagnostic accuracy rate of live videoconferencing (LVC) teledermatology, by board-certified dermatologists compared to non-dermatologists has not yet been fully investigated. The aim of this study was to compare the diagnostic accuracy of board-certified dermatologists, dermatology specialty trainees, and board-certified internists in LVC teledermatology. We examined the diagnostic accuracy of clinicians from different specialties in diagnosing the same group of patients. The clinicians were isolated from each other during the diagnosis process...
March 20, 2024: Journal of Dermatology
https://read.qxmd.com/read/38499181/executive-summary-from-the-medical-board-of-the-national-psoriasis-foundation-perioperative-management-of-immunomodulatory-agents-in-patients-with-psoriasis-and-psoriatic-arthritis
#10
JOURNAL ARTICLE
Warren A James, Angela L Rosenberg, Jashin J Wu, Sylvia Hsu, April Armstrong, Elizabeth B Wallace, Lara Wine Lee, Joseph Merola, Sergio Schwartzman, Dafna Gladman, Clive Liu, John Koo, Jason E Hawkes, Soumya Reddy, Ron Prussick, Paul Yamauchi, Michael Lewitt, Jennifer Soung, Jeffery Weinberg, Mark Lebwohl, Brad Glick, Leon Kircik, Seemal Desai, Steven R Feldman, Mallory L Zaino
No abstract text is available yet for this article.
March 16, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38493762/epidemiology-characteristics-of-disease-and-unmet-needs-of-patients-with-generalized-pustular-psoriasis-a-large-italian-delphi-consensus
#11
JOURNAL ARTICLE
Francesca Prignano, Laura Atzori, Francesco Bellinato, Giovanni Damiani, Carlotta Galeone, Paolo Mariani, Concetta Potenza, Annalisa Scopinaro, Stefano Piaserico, Gabriella Fabbrocini
INTRODUCTION: Generalized pustular psoriasis (GPP) is a rare and chronic, debilitating skin condition characterised, in its acute flare phase, by clinically severe and potentially life-threatening systemic manifestations. Data on GPP are still scanty, particularly in Europe and at a national level. To provide expert indications on several disease-related and patient-related aspects of GPP, with specific focus to the Italian context. METHODS: We conducted an iterative eDelphi study following the recommended criteria for reporting methods and results...
March 17, 2024: Dermatology: International Journal for Clinical and Investigative Dermatology
https://read.qxmd.com/read/38483008/308-nm-excimer-light-is-effective-for-palmoplantar-pustulosis-regardless-of-the-presence-or-absence-of-focal-infection-single-center-real-world-experience-of-treatment-for-palmoplantar-pustulosis
#12
JOURNAL ARTICLE
Yoshiko Niimura, Masahiro Kamata, Takeko Ishikawa, Mayumi Nagata, Makoto Ito, Ayu Watanabe, Shota Egawa, Hideaki Uchida, Azusa Hiura, Saki Fukaya, Kotaro Hayashi, Atsuko Fukuyasu, Takamitsu Tanaka, Yayoi Tada
Palmoplantar pustulosis (PPP) is relatively rare and recognition of PPP is different in different countries. Therefore, real-world data are limited. Local phototherapy for the palms and the soles is commonly used to treat PPP due to tolerable safety. However, data on the effectiveness of 308-nm excimer light are limited. In our study, we retrospectively investigated the effectiveness of treatments for PPP, especially phototherapy (308-nm excimer light), in our department. In addition, we examined whether smoking status and focal infection affected responsiveness to treatment of PPP...
March 14, 2024: Journal of Dermatology
https://read.qxmd.com/read/38460193/a-15-trichloroacetic-acid-3-glycolic-acid-chemical-peel-series-improves-appearance-of-hand-lentigines-an-evaluator-blinded-split-hand-prospective-trial
#13
JOURNAL ARTICLE
Ali Alajmi, Ghassan Niaz, Christine Chen, Kachiu Lee
BACKGROUND: Improving the appearance of lentigines on the hands is a key component to hand rejuvenation. Soft tissue fillers revolumize hands, but do not address pigmentary changes. OBJECTIVE: This study investigated the effiacy of a 15% trichloroacetic acid (TCA) + 3% glycolic acid (GA) combination peel in improvement of appearance of hand lentigines. METHODS: A prospective evaluator-blinded, split-hand study was performed using a 15% TCA + 3% GA peel to treat patients with hand lentigines...
March 8, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://read.qxmd.com/read/38440960/sequential-combination-of-sonic-hedgehog-inhibitors-followed-by-consolidation-radiotherapy-in-locally-advanced-basal-cell-carcinoma
#14
JOURNAL ARTICLE
Marie Boileau, Manon Dubois, Clément Pruvot, Eve Desmedt, Carole Templier, Nicolas Meyer, Xavier Mirabel, Laurent Mortier
BACKGROUND: Sonic Hedgehog inhibitors (SHHis) are an effective treatment in locally advanced basal cell carcinoma (laBCC), but the use of these drugs is limited by adverse events and relapse at discontinuation in around half of patients. A few cases of patients treated concomitantly by radiotherapy (RT) and SHHis have been reported in the literature, suggesting that the combination results in an improved overall response. Maintaining complete response after stopping treatment is a concern, especially since resuming treatment in the case of relapse does not guarantee a new therapeutic response...
March 5, 2024: Clinical and Experimental Dermatology
https://read.qxmd.com/read/38439727/merkel-cell-carcinoma-of-unknown-primary-origin
#15
JOURNAL ARTICLE
Helena Francetić, Luka Simetić, Čedna Tomasović Lončarić, Daška Štulhofer Buzina, Romana Čeović
Merkel cell carcinoma (MCC) is a rare and highly aggressive primary cutaneous neuroendocrine carcinoma most often occurring in the elderly. Risk factors include chronic sun exposure and immunosuppression (1). MCC is associated with frequent recurrences and a high metastatic potential and mortality rate (1). It is the second most common cause of skin-cancer-related death after melanoma. At primary diagnosis with an apparent cutaneous tumor, loco-regional metastases are present in up to 30% of patients, and 6-12% have distant metastatic disease (2-3)...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38422368/bone-and-skin-subcutaneous-tissue-concentrations-of-cefiderocol-during-treatment-of-extensively-drug-resistant-pseudomonas-aeruginosa
#16
JOURNAL ARTICLE
Scott W Mueller, Kyle C Molina, Brittany Blass, Cameron Gibson, Amber D Kohler, Martin Krsak, Arek J Wiktor
Pyoderma gangrenosum is a rare dermatologic disorder that disrupts the skin barrier, requiring immunosuppressive therapy. We successfully used cefiderocol for the treatment of an extensively drug-resistant Pseudomonas aeruginosa bacteremia, and presumed osteomyelitis in a patient with severe pyoderma gangrenosum and associated immunosuppressive therapy while being medically optimized for skin grafting. We obtained bone and skin / subcutaneous tissue while the patient was on cefiderocol under an institutional review board approved biologic waste recovery protocol...
February 29, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://read.qxmd.com/read/38387879/patients-and-caregivers-perspectives-of-the-atopic-dermatitis-journey
#17
JOURNAL ARTICLE
Steven R Feldman, Alson Wai Ming Chan, Alfred Ammoury, Jianzhong Zhang, Akio Tanaka, XingXiang Shi, Amy Cha, Helen Tran
BACKGROUND: Understanding the patient journey is important to optimize care for patients with atopic dermatitis (AD) and overcome challenges in diagnosis and management. OBJECTIVE: To explore patient and caregiver perspectives regarding their experience with AD. METHODS: Patients and caregivers of patients with AD completed a pre-meeting survey and were invited to join an advisory board meeting in their country (China, Hong Kong, Ireland, Japan and Lebanon) to discuss the survey results...
December 2024: Journal of Dermatological Treatment
https://read.qxmd.com/read/38331098/vaccination-recommendations-for-adults-receiving-biologics-and-oral-therapies-for-psoriasis-and-psoriatic-arthritis-delphi-consensus-from-the-medical-board-of-the-national-psoriasis-foundation
#18
JOURNAL ARTICLE
Vipawee S Chat, Christoph T Ellebrecht, Paige Kingston, George Gondo, Stacie Bell, Kelly M Cordoro, Seemal R Desai, Kristina C Duffin, Steven R Feldman, Amit Garg, Joel M Gelfand, Dafna Gladman, Lawrence J Green, Johann Gudjonsson, George Han, Jason E Hawkes, Leon Kircik, John Koo, Richard Langley, Mark Lebwohl, G Michael Lewitt, Wilson Liao, George Martin, Ana-Maria Orbai, Soumya M Reddy, Veronica Richardson, Christopher T Ritchlin, Sergio Schwartzman, Evan L Siegel, Abby S Van Voorhees, Elizabeth B Wallace, Jeffrey M Weinberg, Kevin L Winthrop, Paul Yamauchi, April W Armstrong
BACKGROUND: For psoriatic patients who need to receive nonlive or live vaccines, evidence-based recommendations are needed regarding whether to pause or continue systemic therapies for psoriasis and/or psoriatic arthritis. OBJECTIVE: To evaluate literature regarding vaccine efficacy and safety and to generate consensus-based recommendations for adults receiving systemic therapies for psoriasis and/or psoriatic arthritis receiving nonlive or live vaccines. METHODS: Using a modified Delphi process, 22 consensus statements were developed by the National Psoriasis Foundation Medical Board and COVID-19 Task Force, and infectious disease experts...
February 7, 2024: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/38327550/the-patient-journey-in-facial-aesthetics-findings-from-a-european-consensus-meeting-on-improving-the-quality-of-life-for-patients-receiving-botulinum-toxin-injections
#19
JOURNAL ARTICLE
Wolfgang G Philipp-Dormston, Koenraad De Boulle, Yoav Gronovich, Nick Lowe, Karim Sayed, Dimitrios Sykianakis, Serhan Tuncer
PURPOSE: Successful treatment of facial lines with botulinum toxin is largely dependent on patient satisfaction; thus, a structured treatment journey that uses patient-reported outcomes (PROs) is helpful for maximizing botulinum toxin results. To develop a patient-centric approach for botulinum toxin injections in facial aesthetics, a group of clinicians met to provide opinions on an optimal treatment journey that uses PROs to quantify treatment benefits on patient quality of life. PATIENTS AND METHODS: A multidisciplinary panel of 9 clinicians with expertise in facial aesthetic procedures convened for an advisory board that was preceded by and followed up with a structured, multistep consensus discussion...
2024: Clinical, Cosmetic and Investigational Dermatology
https://read.qxmd.com/read/38306177/themes-and-topics-on-diversity-equity-and-inclusion-in-jmir-dermatology-publications
#20
EDITORIAL
Ramiro Rodriguez, Karima M Osman, Lachlan Anderson, Micah Pascual, Robert P Dellavalle
Publications dealing with topics considered to be pertinent to diversity, equity, and inclusion are increasing. Due to the increasing trend, dermatology journals have started to implement ways to evaluate and understand these publications. Here, we discuss a keyword approach to identify and then categorize these publications. Keywords identified 43 manuscripts. Two reviewers screened the articles' titles and abstracts, and recommended a full manuscript review for 24 publications. Through the scope of definitions from the National Institutes of Health, an editorial board member performed a full-text review and assigned a primary theme to the publications...
February 2, 2024: JMIR dermatology
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