Antonio Luca Spiezia, Fabrizia Falco, Andrea Manganelli, Antonio Carotenuto, Maria Petracca, Federica Novarella, Carmine Iacovazzo, Giuseppe Servillo, Roberta Lanzillo, Vincenzo Brescia Morra, Marcello Moccia
BACKGROUND: Cognitive impairment frequently affects people with multiple sclerosis (MS). Low vitamin D has been associated with cognitive dysfunction in different neurodegenerative diseases, and, in MS, with motor disability and disease activity. We aim to investigate associations between vitamin D and cognitive status in MS. METHODS: In this cross-sectional study, we included 181 MS patients, recruited consecutively at the MS Unit of the Policlinico Federico II University Hospital of Naples, Italy, between January and April 2022, with serum 25‑hydroxy (25-OH) vitamin D measurements using Chemiluminescence-ImmunoAssay, and cognitive assessment using the Brief International Cognitive Assessment for MS (BICAMS), which includes Symbol Digit Modalities Test (SDMT), California Verbal Learning Test-II (CVLT-II) and Brief Visuospatial Memory Test-Revised (BVMT-R)...
November 2023: Multiple Sclerosis and related Disorders