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https://www.readbyqxmd.com/read/28732176/a-comprehensive-craniofacial-study-of-22q11-2-deletion-syndrome
#1
A Lewyllie, J Roosenboom, K Indencleef, P Claes, A Swillen, K Devriendt, C Carels, M Cadenas De Llano-Pérula, G Willems, G Hens, A Verdonck
The 22q11.2 deletion syndrome (22q11.2DS) is one of the most frequent microdeletion syndromes and presents with a highly variable phenotype. In most affected individuals, specific but subtle facial features can be seen. In this observational study, we aim to investigate the craniofacial and dental features of 20 children with a confirmed diagnosis of 22q11.2DS by analyzing 3-dimensional (3D) facial surface scans, 2-dimensional (2D) clinical photographs, panoramic and cephalometric radiographs, and dental casts...
July 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28730243/a-52-year-old-man-with-gouty-arthritis-and-erosive-lesion-in-the-hip
#2
Vitorino Modesto Dos Santos, Viviane Vieira Passini Soares, Priscilla Souza de Faria, Francisca Germanya Morais Borges Viana, Mayza Lemes Duarte
The case study of peripheral and axial gouty arthritis is described in a 52-year-old man without concomitant clinical evidence of tophaceus gout on physical evaluation on admission. Gout is a metabolic disorder related to excess of uric acid in the extracellular compartment, and deposition of monosodium urate crystals in the joints and other sites. Arthritis and tophi are major manifestations, which more often involve the peripheral joints asymmetrically. Chronic tophaceous gout commonly develops after a decade of recurrent polyarticular gout...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28730159/antibiotic-prescribing-for-adults-hospitalized-in-the-etiology-of-pneumonia-in-the-community-study
#3
Sara Tomczyk, Seema Jain, Anna M Bramley, Wesley H Self, Evan J Anderson, Chris Trabue, D Mark Courtney, Carlos G Grijalva, Grant W Waterer, Kathryn M Edwards, Richard G Wunderink, Lauri A Hicks
BACKGROUND: Community-acquired pneumonia (CAP) 2007 guidelines from the Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) recommend a respiratory fluoroquinolone or beta-lactam plus macrolide as first-line antibiotics for adults hospitalized with CAP. Few studies have assessed guideline-concordant antibiotic use for patients hospitalized with CAP after the 2007 IDSA/ATS guidelines. We examine antibiotics prescribed and associated factors in adults hospitalized with CAP...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28729795/cone-beam-computed-tomographic-evaluation-of-styloid-process-a-retrospective-study-of-1000-patients
#4
Merve Donmez, Ozlem Okumus, Filiz Namdar Pekiner
OBJECTIVE: The styloid process (SP) is a bony projection, located just anterior to the stylomastoid foramen, the normal length of which is approximately 20-30 mm. The length of SP when exceeds 30 mm it is said to "elongated." The purpose of this retrospective study was to assess the prevalence of elongated SP (ESP) by cone beam computed tomography (CBCT) examination in Turkish subpopulation and its relation to gender and age. MATERIALS AND METHODS: This study analyzed CBCT of 1000 patients who were randomly selected to participate and were aged from 14 to 78 years...
April 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28726127/clippers
#5
REVIEW
Nicholas L Zalewski, W Oliver Tobin
PURPOSE OF REVIEW: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently described treatable, inflammatory, brainstem predominant encephalomyelitis. The diagnosis of CLIPPERS is challenging without a specific biomarker, and thus it is important to consider if both the clinical and radiographic features are consistent with the diagnosis, or rather a disease mimicker. RECENT FINDINGS: Many patients with CLIPPERS-like lesions have been described in the literature with follow-up revealing a range of alternative diagnoses, such as malignancies, vasculitis, and other specific inflammatory diseases...
September 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28724867/evaluation-of-the-patient-exposure-in-general-radiography-for-some-facilities-comparison-with-drl-and-evaluation-of-the-difference-among-facilities
#6
Koji Ono, Yuya Kondo, Takuma Ichikawa, Yasuki Asada
The first diagnostic reference levels (DRLs 2015) in Japan were published in June 2015. The purpose of this study was to compare the calculated entrance surface doses with the values of DRLs 2015, and evaluate differences in patient exposure among facilities. Semiconductor dosimeter was installed, and dosimetry was performed using equipment and radiographic condition of each facility. As a result, a dose higher than the value of DRLs 2015 was used in 12 kinds of examination. In child chest examination, the doses of the three facilities (0...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28723521/bone-scan-index-and-progression-free-survival-data-for-progressive-metastatic-castration-resistant-prostate-cancer-patients-who-received-odm-201-in-the-arades-multicentre-study
#7
Mariana Reza, Robert Jones, John Aspegren, Christophe Massard, Leena Mattila, Mika Mustonen, Per Wollmer, Elin Trägårdh, Eva Bondesson, Lars Edenbrandt, Karim Fizazi, Anders Bjartell
BACKGROUND: ODM-201, a new-generation androgen receptor inhibitor, has shown clinical efficacy in prostate cancer (PCa). Quantitative methods are needed to accurately assess changes in bone as a measurement of treatment response. The Bone Scan Index (BSI) reflects the percentage of skeletal mass a given tumour affects. OBJECTIVE: To evaluate the predictive value of the BSI in metastatic castration-resistant PCa (mCRPC) patients undergoing treatment with ODM-201...
December 2016: European Urology Focus
https://www.readbyqxmd.com/read/28721354/diagnostic-outcomes-after-chest-radiograph-interpretation-in-patients-with-suspected-tuberculosis-and-negative-sputum-smears-in-a-high-burden-human-immunodeficiency-virus-and-tuberculosis-setting
#8
Patrick G T Cudahy, Rodney Dawson, Brian W Allwood, Gary Maartens, Douglas Wilson
BACKGROUND: Evaluation of patients with suspected tuberculosis and negative sputum smears for acid-fast bacilli (AFB) is challenging, especially in high human immunodeficiency virus coinfection settings where sputum smears have lower sensitivity for detecting AFB. METHODS: We examined the utility of chest radiographs for detecting smear-negative pulmonary tuberculosis. Three hundred sixty sputum smear-negative patients who were referred from primary care clinics in the KwaZulu-Natal province of South Africa were evaluated...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28721303/value-of-99m-tc-mdp-spect-ct-and-18-f-fdg-pet-ct-scanning-in-the-evaluation-of-malignantly-transformed-fibrous-dysplasia
#9
Wei-Jun Wei, Zhen-Kui Sun, Chen-Tian Shen, Xin-Yun Zhang, Juan Tang, Hong-Jun Song, Zhong-Ling Qiu, Quan-Yong Luo
Although fibrous dysplasia is not considered a potentially premalignant disorder, malignant transformation occurs. Because of its rarity, radiographic features of malignantly transformed fibrous dysplasia on cross-sectional imaging modalities are less recognized, making diagnosis and differential diagnosis of the disease quite difficult in clinical practice. In this study, we analyzed the clinical characteristics, imaging features, pathology findings and surgery strategies of 19 malignantly transformed fibrous dysplasia...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28716100/quality-of-life-and-clinical-radiological-long-term-results-after-implant-associated-infections-in-patients-with-ankle-fracture-a-retrospective-matched-pair-study
#10
Patrick Ziegler, Donat Schlemer, Ingo Flesch, Sonja Bahrs, Ulrich Stoeckle, Sebastian Werner, Christian Bahrs
BACKGROUND: Ankle fractures are frequently occurring injuries. Despite the relatively simple operative technique, patients often suffer from postoperative complications. Little is known about postoperative treatment of implant-associated infections of the ankle. Therefore, this study shows and evaluates a treatment algorithm in long- and short-term outcomes compared to infection-free patients. METHODS: Data from patients of over 20 years of a level 1 trauma center and university hospital was retrospectively analyzed including age, gender, comorbidities, smoking status, fracture classification, number of revisions, length of in-patient stay due to fracture and infection, and results of microbiological specimen with the length of antibiotic treatment...
July 17, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28713620/supernumerary-lumbar-ribs-a-rare-occurrence-on-an-adult-african-male-skeleton
#11
Samson Chengetanai, Elsie K Nchabeleng, Nicholas Bacci, Brendon K Billings, Pedzisai Mazengenya
Supernumerary lumbar ribs are usually asymptomatic and discovered incidentally during routine diagnostic radiography. During a routine inventory of the research skeletal repository at the University of the Witwatersrand, a rare case of bilateral supernumerary ribs on the first lumbar vertebra was observed. The skeletal specimen belonged to a 70-year-old African male whose recorded cause of death was esophageal carcinoma. Plain radiography revealed bilateral joint cavities between the transverse processes of the first lumbar vertebra and the supernumerary ribs...
June 2017: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/28713106/prevalence-of-dental-anomalies-in-odisha-population-a-panoramic-radiographic-study
#12
Balasubramanya Goutham, Lipsa Bhuyan, Sangamesh N Chinnannavar, Madhurima Kundu, Kunal Jha, Shyam S Behura
AIM: The aim of this study was to evaluate the prevalence of dental anomalies (DAs) in Odisha population using panoramic radiographs. MATERIALS AND METHODS: In this study, 1,080 panoramic radiographs were evaluated for DAs. Dental records were reviewed for diagnostic confirmation. Anomalies related to the shape, size, position of teeth, and number of roots (supernumerary roots) were evaluated. RESULTS: The study results showed the prevalence of DAs to be 35...
July 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28712699/ct-scout-based-semi-automated-vertebral-morphometry-after-digital-image-enhancement
#13
Wojciech M Glinkowski, Jerzy Narloch
INTRODUCTION: Radiographic diagnosis of osteoporotic vertebral fracture is necessary to reduce its substantial associated morbidity. Computed tomography (CT) scout has recently been demonstrated as a reliable technique for vertebral fracture diagnosis. Software assistance may help to overcome some limitations of that diagnostics. We aimed to evaluate whether digital image enhancement improved the capacity of one of the existing software to detect fractures semi-automatically. METHODS: CT scanograms of patients suffering from osteoporosis, with or without vertebral fractures were analyzed...
June 29, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28709793/dorsal-scaphoid-subluxation-on-sagittal-magnetic-resonance-imaging-as-a-marker-for-scapholunate-ligament-tear
#14
David W Meister, Krystle A Hearns, Michelle G Carlson
PURPOSE: To evaluate the diagnostic utility of scaphoid dorsal subluxation on magnetic resonance imaging (MRI) as a predictor of scapholunate interosseous ligament (SLIL) tears and compare this with radiographic findings. METHODS: Thirty-six MRIs were retrospectively reviewed: 18 with known operative findings of complete Geissler IV SLIL tears that were surgically repaired, and 18 MRIs performed for ulnar-sided wrist pain but no SLIL tear. Dorsal subluxation of the scaphoid was measured on the sagittal MRI cut, which demonstrated the maximum subluxation...
July 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28708778/radiographic-investigation-of-the-distal-extension-of-fractures-into-the-articular-surface-of-the-tibia-the-ridefast-study
#15
Lucas S Marchand, Ajinkya A Rane, Zachary M Working, Lance G Jacobson, Erik N Kubiak, Thomas F Higgins, David L Rothberg
OBJECTIVE: To determine whether radiographic measurements are predictive of involvement of the distal tibia articular surface in tibial shaft fractures. DESIGN: Retrospective review. SETTING: Academic level-I trauma hospital. PATIENTS: Two-hundred seventeen patients with tibial shaft fractures distal to the isthmus (AO/OTA: 42-A1-3;42-B1-3;42-C1-3;43-A1-3). INTERVENTION: Analysis of AP and lateral radiographs...
June 22, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28707526/diagnostic-validity-of-periapical-radiography-and-cbct-for-assessing-periapical-lesions-that-persist-after-endodontic-surgery
#16
Casper Kruse, Rubens Spin-Neto, Jesper Reibel, Ann Wenzel, Lise-Lotte Kirkevang
OBJECTIVES: Traditionally, healing after surgical endodontic retreatment (SER); i.e. apicectomy with or without a retrograde filling, is assessed in periapical radiographs (PR). Recently, the use of Cone Beam CT (CBCT) has increased within endodontics. Generally, CBCT detects more periapical lesions than PR, but basic research on the true nature of these lesions is missing. The objective was to assess the diagnostic validity of PR and CBCT for determining inflammation in SER-cases that were re-operated (SER-R) due to unsuccessful healing, using histology of the periapical lesion as reference for inflammation...
July 14, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28707523/strut-analyses-for-detecting-osteoporosis-using-dental-panoramic-radiography
#17
Jae Joon Hwang, Jeong-Hee Lee, Young Hyun Kim, Ho-Gul Jeong, Yoon Jeong Choi, Wonse Park, Sang-Sun Han
OBJECTIVES: The aim of this study was to identify variables that can be used for osteoporosis detection using strut analysis, fractal dimension (FD), and the gray level co-occurrence matrix (GLCM) using multiple regions of interest (ROIs) and to develop an osteoporosis detection model based on panoramic radiography. METHODS: A total of 454 panoramic radiographs from oral examinations in our dental hospital from 2012 to 2015 were randomly selected, equally distributed among osteoporotic and non-osteoporotic patients (n=227 in each group)...
July 14, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28706752/rationale-of-using-dynamic-imaging-for-characterization-of-suspicious-lung-masses-into-benign-or-malignant-on-contrast-enhanced-multi-detector-computed-tomography
#18
Sachin Khanduri, Saurav Bhagat, Parul Shokeen, Girjesh Kumar, Shobha Khanduri, Bhumika Singh
OBJECTIVES: To assess the utility of dynamic imaging namely, wash-in and wash-out characteristics through multidetector contrast-enhanced computed tomography in differentiating benign and malignant pulmonary masses. MATERIALS AND METHODS: Seventy-three patients who were suspected to have malignant pulmonary mass on the basis of clinical symptoms and chest radiograph were included in the study. All the patients underwent multidetector computed tomography scanning, and three series of images were obtained for each patient-noncontrast, early enhanced, and 15 min delayed enhanced scans...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28704644/amide-proton-transfer-weighted-magnetic-resonance-image-guided-stereotactic-biopsy-in-patients-with-newly-diagnosed-gliomas
#19
Shanshan Jiang, Charles G Eberhart, Yi Zhang, Hye-Young Heo, Zhibo Wen, Lindsay Blair, Huamin Qin, Michael Lim, Alfredo Quinones-Hinojosa, Jon D Weingart, Peter B Barker, Martin G Pomper, John Laterra, Peter C M van Zijl, Jaishri O Blakeley, Jinyuan Zhou
PURPOSE: Pathological assessment using World Health Organization (WHO) criteria is the gold standard for diagnosis of gliomas. However, the accuracy of diagnosis is limited by tissue sampling, particularly for infiltrating, heterogeneous tumours. We assessed the accuracy of amide proton transfer-weighted (APTw) magnetic resonance imaging (MRI)-guided tissue sampling to identify regions of high-grade glioma via radiographic-histopathologic correlation in patients with newly suspected glioma...
July 10, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28700444/multi-institutional-validation-study-of-pancreatic-cyst-fluid-protein-analysis-for-prediction-of-high-risk-intraductal-papillary-mucinous-neoplasms-of-the-pancreas
#20
Mohammad A Al Efishat, Marc F Attiyeh, Anne A Eaton, Mithat Gönen, Denise Prosser, Anna E Lokshin, Carlos Fernández-Del Castillo, Keith D Lillemoe, Cristina R Ferrone, Ilaria Pergolini, Mari Mino-Kenudson, Neda Rezaee, Marco Dal Molin, Matthew J Weiss, John L Cameron, Ralph H Hruban, Michael I D'Angelica, T Peter Kingham, Ronald P DeMatteo, William R Jarnagin, Christopher L Wolfgang, Peter J Allen
OBJECTIVE: Preliminary work by our group suggested that proteins within the pancreatic cyst fluid (CF) may discriminate degree of IPMN dysplasia. We sought to externally validate these markers and determine whether their inclusion in a preoperative clinical nomogram could increase diagnostic accuracy. SUMMARY BACKGROUND DATA: IPMN is the most common radiographically identifiable precursor to pancreatic cancer; however, the timing and frequency of its malignant progression are unknown, and there are currently no reliable preoperative tests that can determine the grade of dysplasia in IPMN...
July 11, 2017: Annals of Surgery
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