Rin Yamaguchi, Maki Tanaka, Keiko Kondo, Toshiro Yokoyama, Ichiro Maeda, Shin-Ichi Tsuchiya, Miki Yamaguchi, Ryuji Takahashi, Yutaka Ogata, Hideyuki Abe, Jun Akiba, Osamu Nakashima, Masayoshi Kage, Hirohisa Yano
Metaplastic breast cancers (MBCs) [spindle cell carcinoma (SpCC), squamous cell carcinoma (SCC), and matrix-producing carcinoma (MPC)] and invasive carcinomas with central acellular zones (CACs) were analyzed with respect to biological potential by immunohistochemical analyses. Specimens from 40 patients [20 with MBCs (7 with SCC, 6 with SpCC, 5 with MPC, and 2 with mixed type)] and 20 with CACs were analyzed using antibodies to cytokeratin (CK) 8, 5/6, 14, AE1/AE3, 34αE12, involucrin, c-kit, vimentin (VIM), alpha-smooth muscle actin, p63, epidermal growth factor receptor, epithelial cell adhesion molecule, and estrogen receptor (ER)/progesterone receptor (PR)/HER2...
December 2012: Medical Molecular Morphology