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https://www.readbyqxmd.com/read/29679599/mortality-in-pulmonary-arterial-hypertension-patients-treated-with-continuous-prostanoids
#1
S D Bartolome, N Sood, T S Shah, K Styrvoky, F T Torres, K M Chin
INTRODUCTION: Parenteral prostanoids are considered the treatment of choice for patients with severe pulmonary arterial hypertension (PAH). Prognostic studies for patients treated in the modern era are limited. METHODS: In this retrospective cohort study, patients initiating IV epoprostenol or IV or SC treprostinil therapy for PAH from 2007-2016 at UT Southwestern, Dallas, TX and Ohio State University, Columbus, OH were included. Transplant-free survival was assessed from the time of IV/SC initiation and from the time of first follow-up...
April 18, 2018: Chest
https://www.readbyqxmd.com/read/29667456/fertility-and-fertility-preservation-knowledge-awareness-and-attitudes-of-female-graduate-students
#2
Lisa C Hickman, Chelsea Fortin, Linnea Goodman, Xiaobo Liu, Rebecca Flyckt
PURPOSE: To evaluate the general knowledge of female graduate students on reproductive aging and fertility preservation options, as well as to investigate the perceptions, personal beliefs, and desires regarding fertility and preservation modalities. MATERIALS AND METHODS: A cross-sectional online survey study of female graduate students and medical trainees from academic institutions in Ohio was performed. Women were excluded if the online survey was incomplete or if they were >45 years...
April 18, 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/29658843/perceptions-of-midwestern-crop-advisors-and-growers-on-foliar-fungicide-adoption-and-use-in-maize
#3
Paul Esker, Denis Anthony Shah, Carl A Bradley, Shawn P Conley, Pierce A Paul, Alison Robertson
Foliar fungicide use in hybrid maize in the United States was rare before 2000. The decade from 2000 to 2010 saw foliar fungicides increasingly applied to maize in the absence of appreciable disease pressure, a practice seemingly at odds with integrated pest management philosophy. Yet, it is commonly believed that growers do not employ management strategies unless there are perceived benefits. Maize (corn) growers (CGs) and certified crop advisors (CCAs) across four Midwestern states (Iowa, Illinois, Ohio and Wisconsin) were surveyed to better understand their practices, values and perceptions concerning the use of foliar fungicides during 2005 to 2009...
April 16, 2018: Phytopathology
https://www.readbyqxmd.com/read/29653256/impact-of-presence-of-children-on-indoor-tobacco-restrictions-in-households-of-urban-and-rural-adult-tobacco-users
#4
Benjamin T Kopp, Alice Hinton, Rong Lu, Sarah Cooper, Haikady Nagaraja, Mary Ellen Wewers
OBJECTIVES: Secondhand smoke exposure (SHSe) in children is changing due to new public policy and electronic nicotine products (e-cigarettes). We examined factors related to self-imposed indoor household tobacco restrictions, with emphasis on children in the household and associations with combustible and non-combustible product use. METHODS: A cross-sectional survey of urban and rural Ohio adult tobacco users classified participants as exclusive combustible users, smokeless tobacco (SLT) users, e-cigarette users, or dual users...
April 10, 2018: Academic Pediatrics
https://www.readbyqxmd.com/read/29651918/updated-report-on-incidence-of-infusion-site-reactions-associated-with-peripheral-intravenous-administration-of-fosaprepitant
#5
Eric Chau, Jordan Lundberg, Gary Phillips, Michael Berger, Robert Wesolowski
Purpose Fosaprepitant (Emend®) is an antiemetic frequently used for the prevention of chemotherapy-induced nausea and vomiting. We previously documented an overall 28.7% incidence of infusion-site reactions in patients receiving fosaprepitant via peripheral venous access. These data resulted in a practice change within our institution; fosaprepitant is administered in more dilute concentrations over 30 min to prevent these adverse events. This retrospective study explored the impact of this practice change on the incidence of infusion-site reactions...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29627023/motor-and-non-motor-features-of-parkinson-s-disease-in-lrrk2-g2019s-carriers-versus-matched-controls
#6
Steven A Gunzler, David E Riley, Shu G Chen, Curtis M Tatsuoka, William M Johnson, John J Mieyal, Ellen M Walter, Christina M Whitney, I Jung Feng, Harry Owusu-Dapaah, Shivam O Mittal, Amy L Wilson-Delfosse
INTRODUCTION: LRRK2 G2019S mutation carriers with Parkinson's disease (PD) have been generally indistinguishable from those with idiopathic PD, with the exception of variable differences in some motor and non-motor domains, including cognition, gait, and balance. LRRK2 G2019S is amongst the most common genetic etiologies for PD, particularly in Ashkenazi Jewish (AJ) populations. METHODS: This cross-sectional data collection study sought to clarify the phenotype of LRRK2 G2019S mutation carriers with PD...
May 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29621925/transport-kinetics-of-chromium-in-perfused-human-placental-lobule-in-late-gestation-in-vitro-study
#7
B Al-Sannan, M Nandakumaran, J Al-Harmi, M Al-Shammari, M Fouda
OBJECTIVE: Reports relating to maternal-fetal transport kinetics of chromium, an essential trace element in the human pregnancies are scanty. Hence, we thought it interesting to investigate the transport kinetics of this trace element in the human placenta in late gestation in vitro. METHODS: Human placentae were collected immediately after delivery from normal uncomplicated pregnancies. Chromium chloride solution (GFS Chem Inc, Ohio, USA) at 10 times the physiological concentrations and antipyrine (Sigma Chem Co...
April 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29620956/clinical-hormonal-and-metabolic-parameters-in-women-with-subclinical-hypothyroidism-and-polycystic-ovary-syndrome-a-cross-sectional-study
#8
Mohamed A Bedaiwy, Mohamed Y Abdel-Rahman, Justin Tan, Faten F AbdelHafez, Amr O Abdelkareem, Drisana Henry, Sarka Lisonkova, William W Hurd, James H Liu
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in reproductive age women, yet its clinical presentation shares similarities with several other endocrine disorders such as thyroid disease. Hence, the objective of this study was to further evaluate this association by investigating the clinical, hormonal, and metabolic parameters between subclinical hypothyroidism (SCH) and PCOS. METHODS: This is a cross-sectional study conducted in a tertiary care clinic at Cleveland, Ohio, USA...
April 5, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29618540/mental-condition-requirement-in-competency-to-stand-trial-assessments
#9
Andrew D Reisner, Jennifer L Piel
In Ohio, a criminal defendant is incompetent to stand trial only if "a present mental condition" renders him unable to understand the nature and objectives of the proceedings against him or to assist in his defense. Some forensic mental health evaluators have treated the mental-condition requirement as synonymous with, or similar to, the psychiatric condition required in the state's insanity criteria, which requires a "severe mental disease or defect." Yet the term mental condition does not appear in other areas of the state's criminal code or in the state's definition of a mental illness for purposes of civil commitment...
March 2018: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/29611769/predictors-of-complications-in-patients-receiving-head-and-neck-free-flap-reconstructive-procedures
#10
Antoine Eskander, Stephen Kang, Ben Tweel, Jigar Sitapara, Matthew Old, Enver Ozer, Amit Agrawal, Ricardo Carrau, James W Rocco, Theodoros N Teknos
Objective To (1) determine the overall complication rate, wound healing, and wound infection complications and (2) identify preoperative, intraoperative, and postoperative predictors of these complications. Study Design Case series with chart review. Setting Tertiary academic cancer hospital. Subjects and Methods All head and neck free flap patients at The Ohio State University (2006-2012) were assessed. Multivariable logistic regression assessed the impact of patient factors, flap and wound factors, and intraoperative factors on the aforementioned quality metric outcomes...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29611730/prevalence-of-human-noroviruses-in-commercial-food-establishment-bathrooms
#11
Cortney M Leone, Muthu Dharmasena, Chaoyi Tang, Erin DiCAPRIO, Yuanmei Ma, Elbashir Araud, Hannah Bolinger, Kitwadee Rupprom, Thomas Yeargin, Jianrong Li, Donald Schaffner, Xiuping Jiang, Julia Sharp, Jan Vinjé, Angela Fraser
Although transmission of human norovirus in food establishments is commonly attributed to consumption of contaminated food, transmission via contaminated environmental surfaces, such as those in bathrooms, may also play a role. Our aim was to determine the prevalence of human norovirus on bathroom surfaces in commercial food establishments in New Jersey, Ohio, and South Carolina under nonoutbreak conditions and to determine characteristics associated with the presence of human norovirus. Food establishments (751) were randomly selected from nine counties in each state...
April 3, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29610676/pregnant-or-recently-pregnant-opioid-users-contraception-decisions-perceptions-and-preferences
#12
Rebecca L Fischbein, Bethany G Lanese, Lynn Falletta, Kelsey Hamilton, Jennifer A King, Deric R Kenne
Background: Multiple factors are linked to extremely high unintended pregnancy rates among women who use opioids, including various barriers to contraception adherence. These include patient level barriers such as lack of knowledge and education about highly effective contraception, and potential provider barriers. Using a mixed-methods framework to examine the contraception-related perceptions and preferences of opioid using women is a necessary next step to understanding this phenomenon...
2018: Contraception and reproductive medicine
https://www.readbyqxmd.com/read/29608357/pervasive-income-based-disparities-in-inpatient-bed-day-rates-across-conditions-and-subspecialties
#13
Andrew F Beck, Carley L Riley, Stuart C Taylor, Cole Brokamp, Robert S Kahn
Building a culture of health in hospitals means more than participating in community partnerships. It also requires an enhanced capacity to recognize and respond to disparities in utilization patterns across populations. We identified all pediatric hospitalizations at Cincinnati Children's Hospital Medical Center, in the period 2011-16. Each hospitalized child's address was geocoded, allowing us to calculate inpatient bed-day rates for each census tract in Hamilton County, Ohio, across all causes and for specific conditions and pediatric subspecialties...
April 2018: Health Affairs
https://www.readbyqxmd.com/read/29606997/characterization-of-the-2016-2017-dermatology-standardized-letter-of-recommendation
#14
Rebecca F Wang, Myron Zhang, Allireza Alloo, Thomas Stasko, Jordan E Miller, Jessica A Kaffenberger
Objective: We aimed to analyze the reformatted standard letter of recommendation (SLOR) for dermatology residents to examine trends in grading and content based on the positions of the letter writers, their backgrounds, and their relationship with the applicant, as well as to evaluate the SLOR's ability to discriminate applicants. Design: This was a retrospective characterization study of dermatology SLORs from the 2016-17 application cycle. Setting: We examined SLORs received by The Ohio State University, the University of Oklahoma, and Hofstra University Northwell Health dermatology residency programs...
March 2018: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29606598/maternal-urinary-phthalate-metabolites-during-pregnancy-and-thyroid-hormone-concentrations-in-maternal-and-cord-sera-the-home-study
#15
Megan E Romano, Melissa N Eliot, R Thomas Zoeller, Andrew N Hoofnagle, Antonia M Calafat, Margaret R Karagas, Kimberly Yolton, Aimin Chen, Bruce P Lanphear, Joseph M Braun
BACKGROUND: Phthalates, endocrine-disrupting chemicals that are commonly found in consumer products, may adversely affect thyroid hormones, but findings from prior epidemiologic studies are inconsistent. OBJECTIVES: In a prospective cohort study, we investigated whether maternal urinary phthalate metabolite concentrations and phthalate mixtures measured during pregnancy were associated with thyroid hormones among pregnant women and newborns. METHODS: We measured nine phthalate metabolites [monoethyl phthalate (MEP), mono-n-butyl phthalate, mono-isobutyl phthalate, monobenzyl phthalate (MBzP), and four monoesthers of di(2-ethylhexyl) phthalate] in urine collected at approximately 16 and 26 weeks' gestation among women in the Health Outcomes and Measures of the Environment Study (2003-2006, Cincinnati, Ohio)...
March 23, 2018: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29602844/impact-of-gestational-weight-gain-and-prepregnancy-body-mass-index-on-the-prevalence-of-large-for-gestational-age-infants-in-two-cohorts-of-women-with-type-1-insulin-dependent-diabetes-a-cross-sectional-population-study
#16
Ketrell L McWhorter, Katherine Bowers, Lawrence M Dolan, Ranjan Deka, Chandra L Jackson, Jane C Khoury
OBJECTIVES: Despite improvements in treatment modalities, large-for-gestational age (LGA) prevalence has remained between 30% and 40% among infants of mothers with type 1 insulin-dependent diabetes mellitus (TIDM). Our objective was to estimate LGA prevalence and examine the association between gestational weight gain (GWG) and prepregnancy body mass index (BMI) with LGA among mothers with TIDM. DESIGN: Cross-sectional study. SETTING: Regional data in Cincinnati, Ohio, from the Diabetes in Pregnancy Program Project (PPG), a prospective cohort for the period 1978-1993; national data from Consortium on Safe Labor (CSL), a multicentre cross-sectional study for the period 2002-2008...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29601613/an-acne-survey-from-the-world-s-largest-annual-gathering-of-twins
#17
Amanda Suggs, Mathew Loesch, Harib Ezaldein, Luisa Christensen, Danyelle Dawes, Elma Baron
IMPORTANCE: Surveying identical twins allows us to qualitatively separate genetic and environmental factors that may contribute to acne severity. OBJECTIVE: To study a cohort of identical and fraternal twins to identify environmental factors that may influence acne severity. DESIGN, SETTING, PARTICIPANTS: A survey was administered to 139 identical and fraternal twin multiples (279 subjects) at the Annual Twins Day Festival in Twinsburg, Ohio on August 6-7, 2016...
April 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29596708/health-benefits-and-risks-of-pets-in-nursing-homes-a-survey-of-facilities-in-ohio
#18
Jason W Stull, Cydney C Hoffman, Timothy Landers
Pets are encountered in nursing homes and although they provide health benefits to individuals, they are also a source of health risks. The current study aimed to determine the frequency and types of animals in nursing homes, perceived benefits, and content of policies addressing health risks. Ninety-five administrators from unique nursing homes in Ohio completed an online survey addressing perceived benefits and risks of animals and policies in place. Animals were permitted in 99% of nursing homes, with dogs (95%), cats (85%), birds (71%), fish (55%), and farm animals (40%) most frequently reported...
March 29, 2018: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/29596542/assessment-of-tumor-sequencing-as-a-replacement-for-lynch-syndrome-screening-and-current-molecular-tests-for-patients-with-colorectal-cancer
#19
Heather Hampel, Rachel Pearlman, Mallory Beightol, Weiqiang Zhao, Daniel Jones, Wendy L Frankel, Paul J Goodfellow, Ahmet Yilmaz, Kristin Miller, Jason Bacher, Angela Jacobson, Electra Paskett, Peter G Shields, Richard M Goldberg, Albert de la Chapelle, Brian H Shirts, Colin C Pritchard
Importance: Universal tumor screening for Lynch syndrome (LS) in colorectal cancer (CRC) is recommended and involves up to 6 sequential tests. Somatic gene testing is performed on stage IV CRCs for treatment determination. The diagnostic workup for patients with CRC could be simplified and improved using a single up-front tumor next-generation sequencing test if it has higher sensitivity and specificity than the current screening protocol. Objective: To determine whether up-front tumor sequencing (TS) could replace the current multiple sequential test approach for universal tumor screening for LS...
March 29, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29595603/ohio-statewide-efforts-to-align-public-health-health-care-population-health-planning
#20
Susan Tilgner, Lance Himes, Terry Allan, Krista Wasowski, Beth Bickford, Wally Burden
No abstract text is available yet for this article.
May 2018: Journal of Public Health Management and Practice: JPHMP
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