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Spinal fusion

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https://www.readbyqxmd.com/read/29028639/implications-of-mitochondrial-dysfunction-for-the-anesthetic-and-perioperative-management-a-case-report-of-spinal-fusion-genetic-confusion-and-a-patient-s-perspective
#1
Linda S Aglio, Brian T Lockhart, Jeantine E Lunshof, Christoph S Nabzdyk
We describe a patient's personal struggle with a symptom complex consisting of profound muscle weakness requiring pyridostigmine, and metabolic abnormalities suggestive of mitochondrial disease. This included a profound sensitivity to opioids, which in the past caused severe respiratory depression during a prior hospital admission. Interestingly, the patient herself is a professor of ethics in genomic sciences, and she and her medical team thus far have not been able to formally diagnose her with mitochondrial disease...
October 12, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29027895/changes-in-foraminal-area-with-anterior-decompression-versus-keyhole-foraminotomy-in-the-cervical-spine-a-biomechanical-investigation
#2
Jacqueline Nguyen, Bryant Chu, Calvin C Kuo, Jeremi M Leasure, Christopher Ames, Dimitriy Kondrashov
OBJECTIVE Anterior cervical discectomy and fusion (ACDF) with or without partial uncovertebral joint resection (UVR) and posterior keyhole foraminotomy are established operative procedures to treat cervical disc degeneration and radiculopathy. Studies have demonstrated reliable results with each procedure, but none have compared the change in neuroforaminal area between indirect and direct decompression techniques. The purpose of this study was to determine which cervical decompression method most consistently increases neuroforaminal area and how that area is affected by neck position...
October 13, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29026131/mechanical-stress-induces-elastic-fibre-disruption-and-cartilage-matrix-increase-in-ligamentum-flavum
#3
Kazunori Hayashi, Akinobu Suzuki, Sayed Abdullah Ahmadi, Hidetomi Terai, Kentaro Yamada, Masatoshi Hoshino, Hiromitsu Toyoda, Shinji Takahashi, Koji Tamai, Shoichiro Ohyama, Akgar Javid, Mohammad Suhrab Rahmani, Maruf Mohammad Hasib, Hiroaki Nakamura
Lumbar spinal stenosis (LSS) is one of the most frequent causes of low back pain and gait disturbance in the elderly. Ligamentum flavum (LF) hypertrophy is the main pathomechanism of LSS, but the reason for its occurrence is not clearly elucidated. In this study, we established a novel animal model of intervertebral mechanical stress concentration and investigated the biological property of the LF. The LF with mechanical stress concentration showed degeneration with elastic fibres disruption and cartilage matrix increase, which are similar to the findings in hypertrophied LF from patients with LSS...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29021683/aarskog-scott-syndrome-an-unusual-cause-of-scoliosis
#4
Kerim Sariyilmaz, Okan Ozkunt, Murat Korkmaz, Fatih Dikici, Unsal Domanic
A 16-year-old boy who had been diagnosed previously as Aarskog-Scott syndrome (AAS), referred to our clinic with shoulder asymmetry for 1 year. Results of spine examination showed a 52° right thoracic curve at T3-T11. Surgery was planned, and T1-L1 posterior instrumentation and fusion were performed. After surgery, satisfactory correction was achieved, and during 10 years follow-up, the patient had no complaints. AAS is a X-linked genetic disorder with facial, genital, and skeletal manifestations. Scoliosis is not reported as a typical finding of AAS, and there is no reported case in the English literature...
July 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29021678/surgical-planning-for-cervical-deformity-based-on-a-3d-model
#5
Juan Barges-Coll, Iulia Peciu-Florianu, Sébastien Martiniere, John Michael Duff
The treatment of fixed cervical deformity is complex, but the principles guiding its correction remain the same as in deformity of other spinal regions, with the goal of deformity correction that results in a solid fusion with adequate decompression of the neural elements. In these challenging cases, osteotomies are necessary to mobilize the rigid spine and to obtain the desired correction, but they can be associated with increased risk of complications. Therefore, careful preoperative planning and a complete understanding of the anatomic variations allow patient-tailored approaches with and case specific techniques for the optimal and safe treatment of a variety of complex cervical deformities...
July 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29021673/risk-factors-for-30-day-outcomes-in-elective-anterior-versus-posterior-cervical-fusion-a-matched-cohort-analysis
#6
John K Yue, Pavan S Upadhyayula, Hansen Deng, David C Sing, Joseph D Ciacci
OBJECTIVE: Cervical spine fusion is the preferred treatment modality for a variety of degenerative and/or myelopathic disorders. Surgeons select between two approaches (anterior or posterior cervical fusion [ACF; PCF]) based on pathoanatomical features and spinal levels involved. Complications and outcome profiles between the approaches following elective surgery have not been systematically investigated. METHODS: Adult patients undergoing elective ACF or PCF were extracted from the American College of Surgeons National Surgical Quality Improvement Program years 2011-2014...
July 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29019902/in-vitro-biomechanical-comparison-after-fixed-and-mobile-core-artificial-cervical-disc-replacement-versus-fusion
#7
Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Tingkui Wu, Hao Liu
In vitro biomechanical analysis after cervical disc replacement (CDR) with a novel artificial disc prosthesis (mobile core) was conducted and compared with the intact model, simulated fusion, and CDR with a fixed-core prosthesis. The purpose of this experimental study was to analyze the biomechanical changes after CDR with a novel prosthesis and the differences between fixed- and mobile-core prostheses.Six human cadaveric C2-C7 specimens were biomechanically tested sequentially in 4 different spinal models: intact specimens, simulated fusion, CDR with a fixed-core prosthesis (Discover, DePuy), and CDR with a mobile-core prosthesis (Pretic-I, Trauson)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29019805/do-obese-and-extremely-obese-patients-lose-weight-after-lumbar-spine-fusions-analysis-of-a-cohort-of-7303-patients-from-the-kaiser-national-spine-registry
#8
Paul T Akins, Maria Cs Inacio, Johannas A Bernbeck, Jessica Harris, Yuexin X Chen, Heather A Prentice, Kern H Guppy
STUDY DESIGN: A retrospective cohort study from the Kaiser Permanente Spine Registry OBJECTIVE.: Determine whether obese and extremely obese patients with lumbar spine fusions lost a clinically significant amount of weight (> 5%) 1 year after their surgery SUMMARY OF BACKGROUND DATA.: Obesity in the United States has a prevalence of 35% and is a global health issue. Obesity is associated with lumbar spine disease. There is limited evidence regarding post-surgical weight loss after spine surgery...
October 10, 2017: Spine
https://www.readbyqxmd.com/read/29019641/spine-conditions-lumbar-spinal-stenosis
#9
Steven D Trigg, Zachary Devilbiss
Lumbar spinal stenosis (LSS) is a frequent cause of chronic low back and lower extremity pain in older patients. Symptomatic LSS typically is described as neurogenic claudication consisting of pain, weakness, numbness, and/or fatigue arising in the back and radiating into the buttock, thigh, or lower leg. The diagnosis is complicated by lack of reliable clinical or x-ray criteria. North American Spine Society guidelines recommend magnetic resonance imaging study without contrast to confirm anatomic narrowing of the spinal canal or nerve root impingement...
October 2017: FP Essentials
https://www.readbyqxmd.com/read/29018937/local-effect-of-zoledronic-acid-on-new-bone-formation-in-posterolateral-spinal-fusion-with-demineralized-bone-matrix-in-a-murine-model
#10
Pawel Zwolak, Jan Farei-Campagna, Thorsten Jentzsch, Brigitte von Rechenberg, Clément M Werner
BACKGROUND: Posterolateral spinal fusion is a common orthopaedic surgery performed to treat degenerative and traumatic deformities of the spinal column. In posteriolateral spinal fusion, different osteoinductive demineralized bone matrix products have been previously investigated. We evaluated the effect of locally applied zoledronic acid in combination with commercially available demineralized bone matrix putty on new bone formation in posterolateral spinal fusion in a murine in vivo model...
October 10, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29018650/surgical-treatment-of-rotational-vertebral-artery-syndrome-induced-by-spinal-tumor-a-case-report-and-literature-review
#11
Shoichi Haimoto, Yusuke Nishimura, Masahito Hara, Yuu Yamamoto, Toshiki Fukuoka, Ryuichi Fukuyama, Toshihiko Wakabayashi, Howard J Ginsberg
Vertebrobasilar insufficiency (VBI) provoked by physiological head rotation is known as rotational vertebral artery syndrome (RVAS) or Bow Hunter syndrome. RVAS most often occurs at C1-2 level with head rotation and presents with symptoms of VBI. Several previously published studies have reported RVAS at subaxial sites (V2 segment), however, tumor-induced RVAS has never been reported. The authors report the first case of RVAS at V2 segment due to compression from a spinal tumor. A 71-year-old man presented with symptoms of dizziness provoked by head rotation or neck extension...
October 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/29017980/predisposing-factors-of-fracture-nonunion-after-posterior-c1-lateral-mass-screws-combined-with-c2-pedicle-laminar-screws-fixation-for-type-ii-odontoid-fracture
#12
Hui Wang
INTRODUCTION: The aim of this study was to explore the predisposing factors for fracture nonunion after C1 lateral screw combined with C2 pedicle/laminar screw for type II odontoid fracture, and hope to provide references in decision making and surgical planning for spinal surgeons. METHODS: This is a retrospective study. By retrieving the medical records from January 2010 to July 2015 in our hospital, 117 type II odontoid fracture patients were reviewed. According to the occurrence of fracture union at the final follow up, patients were divided into two groups: Union group and Non-union group...
October 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29017299/variation-of-c-reactive-protein-and-white-blood-cell-counts-in-spinal-operation-primary-fusion-surgery-versus-revision-fusion-surgery
#13
Kyung Tag Kang, Dong Wuk Son, Su Hun Lee, Geun Seong Song, Soon Ki Sung, Sang Weon Lee
OBJECTIVE: Serum C-reactive protein (CRP) concentrations and white blood cell (WBC) count are commonly used to identify postoperative wound infections. We investigated whether changes in serum CRP levels and WBC counts actually differed between patients undergoing revision spinal fusion surgery and those undergoing a primary fusion. METHODS: Patients who underwent posterolateral fusion (PLF) surgery at Pusan National University Yangsan Hospital between October 2013 and April 2015 were considered for this study...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29016446/incidence-and-risk-factors-of-acute-pancreatitis-following-scoliosis-surgery-a-prospective-study
#14
Fan Feng, Haining Tan, Xingye Li, Yi Qiao, Chong Chen, Youxi Lin, Zheng Li, Jianxiong Shen
STUDY DESIGN: A prospective study. OBJECTIVE: To investigate the incidence and risk factors of acute pancreatitis after scoliosis surgery. SUMMARY OF BACKGROUND DATA: Pancreatitis has been recognized as a possible complication of extra-abdominal surgeries. However, there were few reports on the incidence and risk factors of acute pancreatitis following scoliosis surgery. METHODS: A prospective clinical study was performed at our center from September 2014 to October 2015...
October 9, 2017: Spine
https://www.readbyqxmd.com/read/29016438/ono-1301-enhances-in-vitro-osteoblast-differentiation-and-in-vivo-bone-formation-induced-by-bone-morphogenetic-protein
#15
Sadaaki Kanayama, Takashi Kaito, Kazuma Kitaguchi, Hiroyuki Ishiguro, Kunihiko Hashimoto, Ryota Chijimatsu, Satoru Otsuru, Shota Takenaka, Takahiro Makino, Yusuke Sakai, Akira Myoui, Hideki Yoshikawa
STUDY DESIGN: In vitro and in vivo assessment of osteogenic effect by prostacyclin agonist (ONO-1301) OBJECTIVE.: To investigate the effects of ONO-1301 on in vitro osteoblastic differentiation and in vivo bone formation induced by bone morphogenetic protein (BMP). SUMMARY OF BACKGROUND DATA: Among prostaglandins (PGs), PGE2 is the most abundant in bone tissue and its effects on bone formation have been well studied. PGI2 (prostacyclin) is the second most abundant PG in bone tissue and plays important roles in hemodynamics...
October 9, 2017: Spine
https://www.readbyqxmd.com/read/29016436/trends-and-disparities-in-cervical-spine-fusion-procedures-utilization-in-the-new-york-state
#16
Rui Feng, Mark Finkelstein, Khawaja Bilal, Eric K Oermann, Michael Palese, John Caridi
STUDY DESIGN: A retrospective review of the Statewide Planning and Research Cooperative System database of the New York State. OBJECTIVE: This study examined the rate of increase of cervical spine fusion procedures at low-, medium-, and high-volume hospitals, and analyzed racial and socioeconomic characteristics of the patient population treated at these three volume categories. SUMMARY OF BACKGROUND DATA: There has been a steady increase in spinal fusion procedures performed each year in the US, especially cervical and lumbar fusion...
October 9, 2017: Spine
https://www.readbyqxmd.com/read/28994028/treatment-for-degenerative-lumbar-spondylolisthesis-current-concepts-and-new-evidence
#17
REVIEW
Andre M Samuel, Harold G Moore, Matthew E Cunningham
PURPOSE OF REVIEW: Current guidelines for the optimal treatment degenerative spondylolisthesis are weak and based on limited high-quality evidence. RECENT FINDINGS: There is some moderate evidence that decompression alone may be a feasible treatment with lower surgical morbidity and similar outcomes to fusion when performed in a select population with a low-grade slip. Similarly, addition of interbody fusion may be best suited to a subset of patients with high-grade degenerative spondylolisthesis, although this remains controversial...
October 9, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28993889/recurrent-primary-osseous-hemangiopericytoma-in-the-thoracic-spine-a-case-report-and-literature-review
#18
Takahiro Onoki, Haruo Kanno, Toshimi Aizawa, Ko Hashimoto, Eiji Itoi, Hiroshi Ozawa
PURPOSE: Primary osseous hemangiopericytoma (HPC) of the spine is exceedingly rare. HPC has malignant potential and has the capacity for metastasis and local recurrence. We herein present the first case of recurrent primary osseous HPC in the thoracic spine that was successfully treated by total spondylectomy at three vertebral levels and spinal reconstruction. METHODS: We performed a two-stage operation for recurrent HPC using anterior and posterior approaches at the T5-T7 vertebrae...
October 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28993348/delayed-spinal-cord-infarction-following-anterior-cervical-surgical-decompression
#19
Muhammad Faheem Khan, Rashid Jooma, Fauzan Alam Hashmi, Muhammad Faraz Raghib
Anterior cervical discectomy and fusion (ACDF) for cord compression is a safe and effective procedure with good outcomes. However, worsening of myelopathy is the most feared adverse event of the surgery. We report the case of a 36-year-old male patient who presented with an acute non-traumatic C5-6 cervical disc herniation causing incomplete quadriparesis. He underwent an uncomplicated ACDF at C5-6, and after an initial period of improvement, he developed a delayed onset of an anterior cord syndrome on day 3, without any discerning cause...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28992848/the-first-report-of-human-primary-thoracic-spine-mast-cell-sarcoma-a-case-report
#20
Ali C Ravanpay, Jonathan R Fromm, Kerstin L Edlefsen, Paul Martin, Randal Chesnut
In this report, we present a 53-year-old woman with primary mast cell sarcoma of the thoracic spine vertebrae. Mast cell sarcoma is an aggressive and rare cancer. To date, no cases of primary mast cell sarcoma have been reported in the spinal vertebrae. The patient initially presented with a 1-month history of pelvic and abdominal pain. Inconclusive gynecological evaluation resulted in a CT of the abdomen and pelvis, demonstrating a destructive lesion centered at the 11th thoracic vertebral body. The patient underwent a two-stage spine operation for T11 corpectomy and T7-L3 posterior spinal fusion...
October 10, 2017: Clinical Neuropathology
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