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https://www.readbyqxmd.com/read/28807353/incidence-rates-correlates-and-prognosis-of-electrocardiographic-p-wave-abnormalities-a-nationwide-population-based-study
#1
Arttu O Lehtonen, Ville L Langén, Pauli J Puukka, Mika Kähönen, Markku S Nieminen, Antti M Jula, Teemu J Niiranen
BACKGROUND: Scant data exist on incidence rates, correlates, and prognosis of electrocardiographic P-wave abnormalities in the general population. METHODS: We recorded ECG and measured conventional cardiovascular risk factors in 5667 Finns who were followed up for incident atrial fibrillation (AF). We obtained repeat ECGs from 3089 individuals 11years later. RESULTS: The incidence rates of prolonged P-wave duration, abnormal P terminal force (PTF), left P-wave axis deviation, and right P-wave axis deviation were 16...
July 12, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28772106/frontal-plane-t-wave-axis-orientation-predicts-coronary-events-findings-from-the-moli-sani-study
#2
Licia Iacoviello, Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Livia Rago, Amalia De Curtis, Deodato Assanelli, Fabio Badilini, Martino Vaglio, Mariarosaria Persichillo, Peter W Macfarlane, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano
BACKGROUND AND AIMS: The orientation of the frontal plane T-wave axis (T axis) is a reliable measure of ventricular repolarisation. We investigated the association between T-axis and the risk of coronary heart disease (CHD), heart failure (HF), atrial fibrillation (AF), stroke and cardiovascular (CVD) mortality. METHODS: A sample of 21,287 Moli-sani participants randomly recruited from the general adult (≥35 y) Italian population, free of CVD disease, were followed for a median of 4...
July 22, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28738786/atrial-time-and-voltage-dispersion-are-both-needed-to-predict-new-onset-atrial-fibrillation-in-ischemic-stroke-patients
#3
Daniel Cortez, Maria Baturova, Arne Lindgren, Jonas Carlson, Yuri V Shubik, Bertil Olsson, Pyotr G Platonov
BACKGROUND: Atrial fibrillation (AF) is a known risk factor for ischemic stroke. Electrocardiographic predictors of AF in population studies such as the Framingham Heart Study, as well as in hypertensive patients have demonstrated a predictive value of the P-wave duration for development of AF. QRS vector magnitude has had a predictive value in ventricular arrhythmia development. We aimed to assess the value of the three-dimensional P-wave vector magnitude and its relationship to P-wave duration for prediction of new-onset AF after ischemic stroke...
July 24, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28730171/an-accuracy-study-of-the-intracavitary-electrocardiogram-ic-ecg-guided-peripherally-inserted-central-catheter-tip-placement-among-neonates
#4
Lian-Juan Zhou, Hong-Zhen Xua, Mei-Fang Xu, Yan Hu, Xiao-Fang Lou
OBJECTIVE: To explore the clinical application of the intracavitary electrocardiogram (IC-ECG) guided Peripherally Inserted Central Catheter (PICC) tip placement among neonates. BACKGROUND: the ECGs of neonates are difficult to perform and their wave shapes are of doubtful accuracy due to various interfering factors. METHOD: 115 neonates were admitted to perform PICC guided by IC-ECG. Logistic regression was performed to analyze all possible influencing factors of the accuracy from the tip placement...
2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28696573/prognostic-implications-of-q-waves-at-presentation-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention-an-analysis-of-the-horizons-ami-study
#5
Ioanna Kosmidou, Björn Redfors, Aaron Crowley, Bernard Gersh, Shmuel Chen, José M Dizon, Monica Embacher, Roxana Mehran, Ori Ben-Yehuda, Gary S Mintz, Gregg W Stone
BACKGROUND: Presence of Q waves on the presenting electrocardiogram (ECG) in patients with ST-segment elevation myocardial infarction (STEMI) has been associated with worse prognosis; however, whether the prognostic value of Q waves is influenced by baseline characteristics and/or rapidity of revascularization based on the guideline-based metric of door-to-balloon time remains unknown. HYPOTHESIS: We hypothesized that Q waves in the presenting ECG will be predictive of long term mortality regardless of time to reperfusion...
July 11, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28694394/assessment-of-electrocardiographic-parameters-in-adult-patients-undergoing-extracorporeal-shockwave-lithotripsy
#6
Gündüz Durmuş, Muhsin Kalyoncuoğlu, Mehmet Baran Karataş, Yiğit Çanga, Semi Öztürk, Ender Özal, Yasin Çakıllı, Tuncay Kırış, Barış Güngör, Ahmet Taha Alper, Mehmet Mustafa Can, Osman Bolca
OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) is a safe and effective treatment for urinary tract calculi. While serious side effects are rare, transient cardiac arrhythmias may occur. New electrocardiographic (ECG) parameters, such as P wave dispersion (PWD), QT dispersion (QTd), T peak to T end (Tp-e) interval, Tp-e interval/QT ratio, and Tp-e interval/corrected QT ratio have been defined to help predict atrial and ventricular arrhythmias. However, effect of ESWL on these ECG parameters has not been previously investigated...
July 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28670363/verapamil-suppresses-cardiac-alternans-and-ventricular-arrhythmias-in-acute-myocardial-ischemia-via-ryanodine-receptor-inhibition
#7
Yu-Lei Deng, Jun-Yan Zhao, Ji-Hua Yao, Qiang Tang, Le Zhang, Hong-Lian Zhou, Cun-Tai Zhang, Jia-Gao Lv, Xiao-Qing Quan
T-wave alternans (TWA) is a potent arrhythmia substrate under the conditions of acute myocardial ischemia. Abnormal intracellular calcium cycling contributes to the genesis of cardiac alternans. Ryanodine receptor (RyR) is a pivotal Ca(2+) cycling protein central to Ca(2+) signaling in the heart. Here, we investigated the potential role of RyR in cardiac alternans and ventricular arrhythmias in acute myocardial ischemia. Transmembrane action potentials were simultaneously recorded from epicardium and endocardium together with a transmural ECG and isometric contraction force in the arterially perfused left ventricular wedge preparations...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28657357/ecg-markers-associated-with-ischemic-stroke-at-young-age-a-case-control-study
#8
Jani Pirinen, Antti Eranti, Paul Knekt, Mika Lehto, Nicolas Martinez-Majander, Aapo L Aro, Harri Rissanen, Markku Heliövaara, Markku Kaste, Turgut Tatlisumak, Heikki Huikuri, Jukka Putaala
INTRODUCTION: Certain electrocardiographic (ECG) abnormalities are associated with ischemic stroke (IS), especially cardioembolic subtype. Besides atrial fibrillation, markers of left ventricular hypertrophy (LVH) or atrial pathology also reflect elevated risk. We studied the association of ECG markers with IS in young adults. METHODS: We performed a case-control study including 567 consecutive IS patients aged 15-49 years (inclusion period: 1994-2007) and one or two age- and sex-matched control subjects enrolled during 1978-1980 (n = 1033), and investigated also the stroke aetiologic subgroups...
July 14, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28628659/wave-intensity-of-aortic-root-pressure-as-diagnostic-marker-of-left-ventricular-systolic-dysfunction
#9
Bernhard Hametner, Stephanie Parragh, Thomas Weber, Siegfried Wassertheurer
BACKGROUND: Systolic left ventricular function strongly influences the blood pressure waveform. Therefore, pressure-derived parameters might potentially be used as non-invasive, diagnostic markers of left ventricular impairment. The aim of this study was to investigate the performance of pressure-based parameters in combination with electrocardiography (ECG) for the detection of left ventricular systolic dysfunction defined as severely reduced ejection fraction (EF). METHODS AND RESULTS: Two populations, each comprising patients with reduced EF and pressure-matched controls, were included for the main analysis (51/102 patients) and model testing (44/88 patients)...
2017: PloS One
https://www.readbyqxmd.com/read/28628222/the-value-of-electrocardiography-in-prognosticating-clinical-deterioration-and-mortality-in-acute-pulmonary-embolism-a-systematic-review-and-meta-analysis
#10
REVIEW
Amro Qaddoura, Geneviève C Digby, Conrad Kabali, Piotr Kukla, Zhong-Qun Zhan, Adrian M Baranchuk
The role of electrocardiography (ECG) in prognosticating pulmonary embolism (PE) is increasingly recognized. ECG is quickly interpretable, noninvasive, inexpensive, and available in remote areas. We hypothesized that ECG can provide useful information about PE prognostication. We searched MEDLINE, EMBASE, Google Scholar, Web of Science, abstracts, conference proceedings, and reference lists through February 2017. Eligible studies used ECG to prognosticate for the main outcomes of death and clinical deterioration or escalation of therapy...
June 19, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28626854/spatial-indices-of-repolarization-correlate-with-non-st-elevation-myocardial-ischemia-in-patients-with-chest-pain
#11
Salah Al-Zaiti, Ervin Sejdić, Jan Nemec, Clifton Callaway, Prem Soman, Robert Lux
Mild-to-moderate ischemia does not result in ST segment elevation on the electrocardiogram (ECG), but rather non-specific changes in the T wave, which are frequently labeled as non-diagnostic for ischemia. Robust methods to quantify such T wave heterogeneity can have immediate clinical applications. We sought to evaluate the effects of spontaneous ischemia on the evolution of spatial T wave changes, based on the eigenvalues of the spatial correlation matrix of the ECG, in patients undergoing nuclear cardiac imaging for evaluating intermittent chest pain...
June 19, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28626057/abnormal-p-wave-axis-and-ischemic-stroke-the-aric-study-atherosclerosis-risk-in-communities
#12
Ankit Maheshwari, Faye L Norby, Elsayed Z Soliman, Ryan J Koene, Mary R Rooney, Wesley T O'Neal, Alvaro Alonso, Lin Y Chen
BACKGROUND AND PURPOSE: Abnormal P-wave axis (aPWA) has been linked to incident atrial fibrillation and mortality; however, the relationship between aPWA and stroke has not been reported. We hypothesized that aPWA is associated with ischemic stroke independent of atrial fibrillation and other stroke risk factors and tested our hypothesis in the ARIC study (Atherosclerosis Risk In Communities), a community-based prospective cohort study. METHODS: We included 15 102 participants (aged 54...
August 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28625376/electrocardiographic-abnormalities-and-mortality-in-aging-survivors-of-childhood-cancer-a-report-from-the-st-jude-lifetime-cohort-study
#13
Daniel A Mulrooney, Elsayed Z Soliman, Matthew J Ehrhardt, Lu Lu, Daniel A Duprez, Russell V Luepker, Gregory T Armstrong, Vijaya M Joshi, Daniel M Green, Deokumar Srivastava, Matthew J Krasin, G Stephen Morris, Leslie L Robison, Melissa M Hudson, Kirsten K Ness
BACKGROUND: Electrocardiography (ECG), predictive of adverse outcomes in the general population, has not been studied in cancer survivors. We evaluated the prevalence of ECG abnormalities and associations with mortality among childhood cancer survivors. METHODS: Major and minor abnormalities were coded per the Minnesota Classification system for participants in the St Jude Lifetime Cohort Study (n = 2,715) and community controls (n = 268). Odds ratios (ORs) and 95% CIs were calculated using multivariable logistic regression; and hazard ratios, using Cox proportional hazards regression...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28546456/electrocardiographic-predictors-of-heart-failure-with-reduced-versus-preserved-ejection-fraction-the-multi-ethnic-study-of-atherosclerosis
#14
Wesley T O'Neal, Matylda Mazur, Alain G Bertoni, David A Bluemke, Mouaz H Al-Mallah, Joao A C Lima, Dalane Kitzman, Elsayed Z Soliman
BACKGROUND: Several markers detected on the routine 12-lead ECG are associated with future heart failure events. We examined whether these markers are able to separate the risk of heart failure with reduced ejection fraction (HFrEF) from heart failure with preserved ejection fraction (HFpEF). METHODS AND RESULTS: We analyzed data of 6664 participants (53% female; mean age 62±10 years) from MESA (Multi-Ethnic Study of Atherosclerosis) who were free of cardiovascular disease at baseline (2000-2002)...
May 25, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28526702/t-wave-morphology-restitution-predicts-sudden-cardiac-death-in-patients-with-chronic-heart-failure
#15
Julia Ramírez, Michele Orini, Ana Mincholé, Violeta Monasterio, Iwona Cygankiewicz, Antonio Bayés de Luna, Juan Pablo Martínez, Esther Pueyo, Pablo Laguna
BACKGROUND: Patients with chronic heart failure are at high risk of sudden cardiac death (SCD). Increased dispersion of repolarization restitution has been associated with SCD, and we hypothesize that this should be reflected in the morphology of the T-wave and its variations with heart rate. The aim of this study is to propose an electrocardiogram (ECG)-based index characterizing T-wave morphology restitution (TMR), and to assess its association with SCD risk in a population of chronic heart failure patients...
May 19, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28522299/most-advisable-strategy-in-search-of-asymptomatic-target-organ-damage-in-hypertensive-patients
#16
J Abellán-Huerta, L Prieto-Valiente, L Consuegra-Sánchez, S Montoro-García, A B Salguero-Merino, R Morales-López, J Abellán-Alemán, F Soria-Arcos
OBJECTIVE: To evaluate the diagnostic potential of seven examinations in order to define the most suitable strategy for target organ damage (TOD) search in hypertensive patients. METHODS: This is a descriptive, cross-sectional study. 153 consecutive treated and essential hypertensive patients were enrolled. Patients with established cardiovascular or chronic renal disease (stage ≥4) were excluded. TOD search was assessed by: glomerular filtration rate (GFR), albumin/creatinine ratio (ACR), electrocardiogram (ECG), echocardiogram (ECO), ankle-brachial index (ABI), pulse wave velocity (PWV), and carotid ultrasound (intima media thickness and presence of plaques)...
May 15, 2017: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/28520655/effectiveness-of-intracavitary-electrocardiogram-guidance-in-peripherally-inserted-central-catheter-tip-placement-in-neonates
#17
Lianjuan Zhou, Hongzhen Xu, Jianfeng Liang, Meifang Xu, Jun Yu
Correct tip location is crucial for a peripherally inserted central catheter (PICC) to maximize the effects of central venous infusion. However, it is difficult to place the tip in a correct location in neonates because of the unreliable estimated length by surface landmark. Therefore, we evaluated the feasibility and safety of an improved intracavitary electrocardiogram (IC-ECG) technique in guiding PICC placement in neonates based on the ratios of P/R wave amplitudes on IC-ECG. The results showed that all of the 32 neonates whose PICCs had been successfully placed and correct tip position verified by chest radiography acquired qualified P wave on IC-ECG...
May 17, 2017: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/28465114/heart-failure-in-patients-with-arrhythmogenic-right-ventricular-cardiomyopathy-what-are-the-risk-factors
#18
Yoshitaka Kimura, Takashi Noda, Taka-Aki Matsuyama, Yosuke Otsuka, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Yuko Inoue, Koji Miyamoto, Hideo Okamura, Satoshi Nagase, Takeshi Aiba, Shiro Kamakura, Teruo Noguchi, Toshihisa Anzai, Kazuhiro Satomi, Yuko Wada, Seiko Ohno, Minoru Horie, Wataru Shimizu, Satoshi Yasuda, Hiroaki Shimokawa, Kengo Kusano
BACKGROUND: We previously demonstrated that heart failure (HF) was one of the major causes of death in arrhythmogenic right ventricular cardiomyopathy (ARVC). The purpose of this study was to elucidate the clinical impact and risk factors of HF in patients with ARVC. METHODS AND RESULTS: We evaluated cardiac adverse outcomes including HF in 113 consecutive patients with ARVC (85 men, mean age: 44±15years). During a median follow-up of 10.0years (interquartile range: 5...
April 21, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28460689/a-new-4-variable-formula-to-differentiate-normal-variant-st-segment-elevation-in-v2-v4-early-repolarization-from-subtle-left-anterior-descending-coronary-occlusion-adding-qrs-amplitude-of-v2-improves-the-model
#19
Brian E Driver, Ayesha Khalil, Timothy Henry, Faraz Kazmi, Amina Adil, Stephen W Smith
INTRODUCTION: Precordial normal variant ST elevation (NV-STE), previously often called "early repolarization," may be difficult to differentiate from subtle ischemic STE due to left anterior descending (LAD) occlusion. We previously derived and validated a logistic regression formula that was far superior to STE alone for differentiating the two entities on the ECG. The tool uses R-wave amplitude in lead V4 (RAV4), ST elevation at 60 ms after the J-point in lead V3 (STE60V3) and the computerized Bazett-corrected QT interval (QTc-B)...
April 19, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28453441/fetal-cardiac-time-intervals-in-healthy-pregnancies-an-observational-study-by-fetal-ecg-monica-healthcare-system
#20
Annette Wacker-Gussmann, Cordula Plankl, Maria Sewald, Karl-Theo Maria Schneider, Renate Oberhoffer, Silvia M Lobmaier
BACKGROUND: Fetal electrocardiogram (fECG) can detect QRS signals in fetuses from as early as 17 weeks' gestation; however, the technique is limited by the minute size of the fetal signal relative to noise ratio. The aim of this study was to evaluate precise fetal cardiac time intervals (fCTIs) with the help of a newly developed fetal ECG device (Monica Healthcare System). METHODS: In a prospective manner we included 15-18 healthy fetuses per gestational week from 32 weeks onwards...
April 28, 2017: Journal of Perinatal Medicine
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