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https://www.readbyqxmd.com/read/29146669/relationships-between-baseline-q-waves-time-from-symptom-onset-and-clinical-outcomes-in-st-segment-elevation-myocardial-infarction-patients-insights-from-the-vital-heart-response-registry
#1
Yinggan Zheng, Kevin R Bainey, Benjamin D Tyrrell, Neil Brass, Paul W Armstrong, Robert C Welsh
BACKGROUND: Using a comprehensive ST-segment-elevation myocardial infarction registry, we evaluated the relationships of baseline Q waves, time from symptom onset, and reperfusion strategy with in-hospital clinical outcomes. METHODS AND RESULTS: Consecutive ST-segment-elevation myocardial infarction patients from a defined health region were classified by the presence of baseline Q waves and additionally into primary percutaneous coronary intervention, fibrinolysis, or no reperfusion...
November 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29141844/architectural-t-wave-analysis-and-identification-of-on-therapy-breakthrough-arrhythmic-risk-in-type-1-and-type-2-long-qt-syndrome
#2
Alan Sugrue, Ram K Rohatgi, Peter A Noseworthy, Vaclav Kremen, J Martijn Bos, Bo Qiang, Yehu Sapir, Zachi I Attia, Christopher G Scott, Peter Brady, Samuel J Asirvatham, Paul A Friedman, Michael J Ackerman
BACKGROUND: Although the hallmark of long-QT syndrome (LQTS) is abnormal cardiac repolarization, there are varying degrees of phenotypic expression and arrhythmic risk. Our aim was to evaluate the performance of a morphological T-wave analysis program in defining breakthrough LQTS arrhythmic risk beyond the QTc value. METHODS AND RESULTS: We analyzed 407 genetically confirmed patients with LQT1 (n=246; 43% men) and LQT2 (n=161; 41% men) over the mean follow-up period of 6...
November 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29129560/the-role-of-holter-monitoring-in-the-diagnosis-of-early-repolarisation-pattern
#3
Cheng-Cheng Ji, Xu-Miao Chen, Yun-Jiu Cheng, Li-Juan Liu, Kai Tang, Wei-Qi Zhu, Ying Huang, Wei-Ying Chen, Wei-Ying Chen, Su-Hua Wu
BACKGROUND: A slower heart rate can exaggerate J-point elevation in a 12-lead ECG. This study examined the role of Holter monitoring in the diagnosis of early repolarisation pattern (ERP). METHODS: We examined 24-hour Holter recordings of 4000 consecutive patients seen at an outpatient clinic, and found 500 patients (12.5%) with ERP (based on J-point elevation magnitude maximum value≥0.1mV on the Holter recording). The highest magnitude of J-point elevation, R wave amplitude, the ratio between J-point elevation magnitude and R-wave amplitude on the same ECG lead (J/R ratio), QRS interval, and QT/QTc interval were measured on the Holter recording and on a surface 12-lead ECG of the 500 patients with ERP...
October 20, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29113641/a-simple-independent-prognostic-electrocardiography-parameter-in-first-acute-anterior-myocardial-infarction-precordial-total-q-wave-precordial-total-r-wave
#4
Mert İlker Hayıroğlu, Ahmet Okan Uzun, Muhammed Keskin, Edibe Betül Börklü, Ahmet İlker Tekkeşin, Ceyhan Türkkan, Ömer Kozan
BACKGROUND: We investigated the prognostic value of precordial total Q wave amplitude/precordial total R wave amplitude ratio (Q/R) in patients with first acute anterior MI treated with primary percutaneous coronary intervention (PPCI). METHODS: We evaluated the in-hospital prognostic impact of Q/R on 354 patients with first acute anterior MI. Patients were stratified by tertiles of admission Q/R, clinical outcomes were compared between those groups. RESULTS: In-hospital univariate analysis revealed notably higher rates of in-hospital death for patients in tertile 3, as compared to patients in tertile 1 (OR 9...
September 27, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29100617/relationship-between-frequency-spectrum-of-heart-rate-variability-and-autonomic-nervous-activities-during-sleep-in-newborns
#5
Tsunenori Takatani, Yukihiro Takahashi, Ryota Yoshida, Ryuko Imai, Takao Uchiike, Masaharu Yamazaki, Midori Shima, Toshiya Nishikubo, Yoshito Ikada, Shinichi Fujimoto
INTRODUCTION: We analyzed the frequency spectrum of two neonatal sleep stages, namely active sleep and quiet sleep, and the relationship between these sleep stages and autonomic nervous activity in 74 newborns and 16 adults as a comparison. METHOD: Active and quiet sleep were differentiated by electroencephalogram (EEG) patterns, eye movements, and respiratory wave patterns; autonomic activity was analyzed using the RR interval of simultaneously recorded electrocardiogram (ECG) signals...
October 31, 2017: Brain & Development
https://www.readbyqxmd.com/read/29067908/evaluation-of-baseline-ecg-in-patients-undergoing-oral-flecainide-challenge-test-for-suspected-brugada-syndrome-an-analysis-of-lead-ii
#6
Maneesh K Rai, Mukund A Prabhu, Jayaprakash Shenthar, Natarajan Kumaraswamy U, Ritesh Vekariya, Padmanabh Kamath, Narasimha Pai, Ramanath L Kamath, Vivek Pillai
BACKGROUND AND OBJECTIVES: We analyzed Lead II in patients undergoing an Oral Flecainide Challenge test (FCT), to identify any pointers that could predict a positive FCT and thereby help in recognition of latent BS. METHODS: The following parameters in lead II were retrospectively analyzed from the pre-test ECG in 62 patients undergoing FCT for suspected BS: The presence or absence of S waves, S wave amplitude, duration and upslope duration; J point parameters- Early repolarization, QRS notch, and QRS Slur; ST segment parameters-lack of isoelectric ST segment, ST duration and QT interval...
July 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29067654/cardiac-involvement-in-duchenne-muscular-dystrophy-and-related-dystrophinopathies
#7
Sophie I Mavrogeni, George Markousis-Mavrogenis, Antigoni Papavasiliou, George Papadopoulos, Genovefa Kolovou
Dystrophinopathies include Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), X-linked dilated cardiomyopathy (XLCM), and facioscapulohumeral muscular dystrophy (FSHD). DMD/BMD are X-linked recessive disorders, related to the synthesis of dystrophin. Most of DMD after the third decade of their age develop cardiomyopathy that remains silent, due to relative physical inactivity. Cardiac disease in female carriers presents with hypertrophy, arrhythmias or dilated cardiomyopathy, clinically overt by increasing age...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29059978/using-a-new-ppg-indicator-to-increase-the-accuracy-of-ptt-based-continuous-cuffless-blood-pressure-estimation
#8
Wan-Hua Lin, Hui Wang, Oluwarotimi Williams Samuel, Guanglin Li
Pulse transit time (PTT) has been identified as a potential indicator to estimate blood pressure (BP) continuously and cufflessly in the previous studies, but it is still unsatisfactory for clinical uses. In order to improve the BP estimation accuracy, another candidate signal, photoplethysmogram (PPG) has been used to estimate continuous BP. In this study, a new PPG indicator, the intensity ratio of the first derivative wave of PPG (1(st) dPIR), was proposed and a novel BP estimation algorithm by using both PTT and 1(st) dPIR was developed with an attempt to further increase the BP estimation accuracy...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059602/superovulatory-response-following-fsh-ecg-fsh-and-hmg-and-pregnancy-rates-following-transfer-of-hatched-blastocyst-embryos-with-different-diameter-and-shape-in-dromedary-camel
#9
Tahereh Ararooti, Amir Niasari-Naslaji, Behnam Asadi-Moghaddam, Kamal Razavi, Farnaz Panahi
The objectives of this study were to compare three superovulation protocols and to investigate the effect of embryo diameter and shape on pregnancy rates in dromedary camel. In Experiment 1, following follicular wave synchronization of donors using two injections of GnRH (25 μg, im), superovulation was initiated 2 days after the second GnRH (Day 0 of experiment). Then, donors were assigned into three groups (n = 5) and received 1) FSH alone (390 mg), 2) eCG (1000 IU; single dose on Day 0) and FSH (330 mg) and 3) hMG (17...
October 13, 2017: Theriogenology
https://www.readbyqxmd.com/read/29030380/association-between-qt-interval-components-and-sudden-cardiac-death-the-aric-study-atherosclerosis-risk-in-communities
#10
MULTICENTER STUDY
Wesley T O'Neal, Matthew J Singleton, Jason D Roberts, Larisa G Tereshchenko, Nona Sotoodehnia, Lin Y Chen, Gregory M Marcus, Elsayed Z Soliman
BACKGROUND: Several reports have demonstrated that prolongation of the QT interval is associated with sudden cardiac death (SCD). However, it is unknown whether any of the components within the QT interval are responsible for its association with SCD. METHODS AND RESULTS: We examined the association of the individual QT-interval components (R-wave onset to R-peak, R-peak to R-wave end, ST-segment, T-wave onset to T-peak, and T-peak to T-wave end) with SCD in 12 241 participants (54±5...
October 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29029613/right-precordial-directed-electrocardiographical-markers-identify-arrhythmogenic-right-ventricular-cardiomyopathy-in-the-absence-of-conventional-depolarization-or-repolarization-abnormalities
#11
Daniel Cortez, Anneli Svensson, Jonas Carlson, Sharon Graw, Nandita Sharma, Francesca Brun, Anita Spezzacatene, Luisa Mestroni, Pyotr G Platonov
BACKGROUND: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) carries a risk of sudden death. We aimed to assess whether vectorcardiographic (VCG) parameters directed toward the right heart and a measured angle of the S-wave would help differentiate ARVD/C with otherwise normal electrocardiograms from controls. METHODS: Task Force 2010 definite ARVD/C criteria were met for all patients. Those who did not fulfill Task Force depolarization or repolarization criteria (-ECG) were compared with age and gender-matched control subjects...
October 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29020031/sudden-cardiac-death-and-pump-failure-death-prediction-in-chronic-heart-failure-by-combining-ecg-and-clinical-markers-in-an-integrated-risk-model
#12
Julia Ramírez, Michele Orini, Ana Mincholé, Violeta Monasterio, Iwona Cygankiewicz, Antonio Bayés de Luna, Juan Pablo Martínez, Pablo Laguna, Esther Pueyo
BACKGROUND: Sudden cardiac death (SCD) and pump failure death (PFD) are common endpoints in chronic heart failure (CHF) patients, but prevention strategies are different. Currently used tools to specifically predict these endpoints are limited. We developed risk models to specifically assess SCD and PFD risk in CHF by combining ECG markers and clinical variables. METHODS: The relation of clinical and ECG markers with SCD and PFD risk was assessed in 597 patients enrolled in the MUSIC (MUerte Súbita en Insuficiencia Cardiaca) study...
2017: PloS One
https://www.readbyqxmd.com/read/29019518/prevalence-and-predictive-value-of-electrocardiographic-abnormalities-in-pulmonary-hypertension-evidence-from-the-pan-african-pulmonary-hypertension-cohort-papuco-study
#13
Irina Balieva, Anastase Dzudie, Friedrich Thienemann, Ana O Mocumbi, Kamilu Karaye, Mahmoud U Sani, Okechukwu S Ogah, Adriaan A Voors, Andre Pascal Kengne, Karen Sliwa
BACKGROUND: Pulmonary hypertension (PH) is prevalent in Africa and is still often diagnosed only at an advanced stage, therefore it is associated with poor quality of life and survival rates. In resource-limited settings, we assessed the diagnostic utility of standard 12-lead electrocardiograms (ECG) to detect abnormalities indicating PH. METHODS: Sixty-five patients diagnosed with PH were compared with 285 heart disease-free subjects. The prevalence and diagnostic performance of ECG features indicative of PH and right heart strain were calculated...
October 11, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28991216/adaptive-integration-of-the-compressed-algorithm-of-cs-and-npc-for-the-ecg-signal-compressed-algorithm-in-vlsi-implementation
#14
Yun-Hua Tseng, Yuan-Ho Chen, Chih-Wen Lu
Compressed sensing (CS) is a promising approach to the compression and reconstruction of electrocardiogram (ECG) signals. It has been shown that following reconstruction, most of the changes between the original and reconstructed signals are distributed in the Q, R, and S waves (QRS) region. Furthermore, any increase in the compression ratio tends to increase the magnitude of the change. This paper presents a novel approach integrating the near-precise compressed (NPC) and CS algorithms. The simulation results presented notable improvements in signal-to-noise ratio (SNR) and compression ratio (CR)...
October 9, 2017: Sensors
https://www.readbyqxmd.com/read/28988456/electrocardiographic-features-of-failed-and-recurrent-right-ventricular-outflow-tract-catheter-ablation-of-idiopathic-ventricular-arrhythmias
#15
Shinya Yamada, Fa-Po Chung, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Chung-Hsing Lin, Chin-Yu Lin, Yao-Ting Chang, Ting-Yung Chang, Abigail Louise D Te, Shih-Ann Chen
INTRODUCTION: Various ECG algorithms have been proposed to identify the origin of idiopathic outflow tract (OT)-ventricular arrhythmia (VA). However, electrocardiographic features of failed and recurrent right ventricular outflow tract (RVOT) ablation of idiopathic OT-VAs have not been clearly elucidated. METHODS AND RESULTS: A total of 264 consecutive patients (mean age: 44.0±13.0 years, 96 male) undergoing RVOT ablation for OT-VAs with a transition ≥ V3 , including 241 patients (91...
October 8, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28972986/ecg-data-compression-using-a-neural-network-model-based-on-multi-objective-optimization
#16
Bo Zhang, Jiasheng Zhao, Xiao Chen, Jianhuang Wu
Electrocardiogram (ECG) data analysis is of great significance to the diagnosis of cardiovascular disease. ECG compression should be processed in real time, and the data should be based on lossless compression and have high predictability. In terms of the real time aspect, short-time Fourier transformation is applied to the processing of signal wave for reducing computational time. For the lossless compression requirement, wavelet-transformation that is a coding algorithm can be used to avoid loss of data. In practice, compression is required to avoid storing redundant recording data that are not useful in the diagnosis platform...
2017: PloS One
https://www.readbyqxmd.com/read/28965260/the-t-peak-to-t-end-interval-a-novel-ecg-marker-for-ventricular-arrhythmia-and-appropriate-icd-therapy-in-patients-with-hypertrophic-cardiomyopathy
#17
Leon Dinshaw, Julia Münch, Jannis Dickow, Susanne Lezius, Stephan Willems, Boris A Hoffmann, Monica Patten
INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is associated with an increased risk of sudden cardiac death (SCD) primarily due to ventricular arrhythmia (VA). In patients (pts.) with a high risk of SCD, the implantation of an intracardiac cardioverter defibrillator (ICD) is thus indicated. Previous studies suggest that a prolonged interval between the peak and the end of the T wave, T-peak to T-end (TpTe), is associated with an elevated risk of VA and SCD in various clinical settings...
September 30, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28952588/a-proof-of-concept-study-simple-and-effective-detection-of-p-and-t-waves-in-arrhythmic-ecg-signals
#18
Mohamed Elgendi, Marianna Meo, Derek Abbott
A robust and numerically-efficient method based on two moving average filters, followed by a dynamic event-related threshold, has been developed to detect P and T waves in electrocardiogram (ECG) signals as a proof-of-concept. Detection of P and T waves is affected by the quality and abnormalities in ECG recordings; the proposed method can detect P and T waves simultaneously through a unique algorithm despite these challenges. The algorithm was tested on arrhythmic ECG signals extracted from the MIT-BIH arrhythmia database with 21,702 beats...
October 17, 2016: Bioengineering
https://www.readbyqxmd.com/read/28947311/six-year-outcome-of-subjects-without-overt-heart-disease-with-an-early-repolarization-j-wave-electrocardiographic-pattern
#19
Gaetano Antonio Lanza, Alessia Argirò, Roberto Mollo, Antonio De Vita, Francesco Spera, Michele Golino, Elisabetta Rota, Monica Filice, Filippo Crea
"Early repolarization" (ER) is a frequent finding at standard electrocardiogram (ECG). In this study we assessed whether ER is associated with an increased risk of events, as recently suggested by some studies. We prospectively enrolled 4,176 consecutive subjects without any heart disease who underwent routine ECG recording. ER was diagnosed in case of typical concave ST-segment elevation ≥0.1 mV; a J wave was diagnosed when the QRS showed a notch or a slur in its terminal part. In this study we compared the 6-year outcome of all 687 subjects with ER/J wave and 687 matched subjects without ER/J wave (controls)...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28892227/dynamic-changes-of-qtc-interval-and-prognostic-significance-in-takotsubo-stress-cardiomyopathy
#20
Francesco Santoro, Natale Daniele Brunetti, Nicola Tarantino, Jorge Romero, Francesca Guastafierro, Armando Ferraretti, Luigi F M Di Martino, Riccardo Ieva, Pier Luigi Pellegrino, Matteo Di Biase, Luigi Di Biase
BACKGROUND: Prolonged QT corrected (QTc) intervals are associated with adverse cardiovascular outcomes both in healthy and high-risk populations. Our objective was to evaluate the QTc intervals during a takotsubo cardiomyopathy (TTC) episodes and their potential prognostic role. HYPOTHESIS: Dynamic changes of QTc interval during hospitalization for TTC could be associated with outcome at follow-up. METHODS: Fifty-two consecutive patients hospitalized for TTC were enrolled...
September 11, 2017: Clinical Cardiology
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