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https://www.readbyqxmd.com/read/28636832/nutrient-deficiencies-are-common-prior-to-bariatric-surgery
#1
Leigh A Frame-Peterson, Robin D Megill, Suzanne Carobrese, Michael Schweitzer
Obesity, defined as a body mass index >30 kg/m(2), is a growing worldwide epidemic currently effecting 1 in 10 adults, with rates as high as 40% in the United States. The only proven long-term treatment of severe obesity on a population level is surgical modification of the gastrointestinal anatomy to induce weight loss, termed bariatric surgery. With adequate physician guidance and appropriate candidate criteria, bariatric surgery is an option for effective long-term treatment of obesity and its related comorbidities...
June 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28631871/efficacy-of-percutaneous-endoscopic-gastro-jejunostomy-peg-j-decompression-therapy-for-patients-with-chronic-intestinal-pseudo-obstruction-cipo
#2
H Ohkubo, A Fuyuki, J Arimoto, T Higurashi, T Nonaka, Y Inoh, H Iida, M Inamori, T Kaneda, A Nakajima
BACKGROUNDS: Chronic intestinal pseudo-obstruction (CIPO) is an intractable rare digestive disease manifesting persistent small bowel distension without any mechanical cause. Intestinal decompression is a key treatment, but conventional method including a trans-nasal small intestinal tube is invasive and painful. Therefore, a less invasive and tolerable new decompression method is urgently desired. We conducted a pilot study and assessed the efficacy and safety of percutaneous endoscopic gastro-jejunostomy (PEG-J) decompression therapy in CIPO patients...
June 20, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28628496/proton-pump-inhibitor-and-selective-serotonin-reuptake-inhibitor-therapy-for-the-management-of-noncardiac-chest-pain
#3
Nikos Viazis, Konstantina Katopodi, George Karamanolis, Konstantinos Denaxas, Lazaros Varytimiadis, Michail Galanopoulos, Emmanouela Tsoukali, Dimitirs Kamberoglou, Angeliki Christidou, Dimitrios G Karamanolis, George Papatheodoridis, Gerasimos J Mantzaris
INTRODUCTION: Although gastroesophageal reflux disease is the main cause of noncardiac chest pain (NCCP), proton pump inhibitors (PPIs) benefit a minority of patients. Our prospective study evaluated the effect of PPI and selective serotonin reuptake inhibitors on the different subtypes of NCCP characterized by impedance-pH monitoring. METHODS: All NCCP patients underwent impedance-pH monitoring and on the basis of the results, those with abnormal distal esophageal acid exposure received PPIs twice daily (group A), those with a positive symptom index for chest pain received citalopram 20 mg and PPI once daily (group B), and those with a negative symptom index for chest pain received citalopram 20 mg once daily (group C)...
June 16, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28627413/modeling-esophagitis-using-human-three-dimensional-organotypic-culture-system
#4
Dorottya Laczkó, Fang Wang, F Bradley Johnson, Nirag Jhala, András Rosztóczy, Gregory G Ginsberg, Gary W Falk, Anil K Rustgi, John P Lynch
Esophagitis, whether caused by acid reflux, allergic responses, graft-versus-host disease, drugs, or infections, is a common condition of the gastrointestinal tract affecting nearly 20% of the US population. The instigating agent typically triggers an inflammatory response. The resulting inflammation is a risk factor for the development of esophageal strictures, Barrett esophagus, and esophageal adenocarcinoma. Research into the pathophysiology of these conditions has been limited by the availability of animal and human model systems...
June 13, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28626103/-study-on-lifestyle-in-patients-with-gastroesophageal-%C3%A2-reflux-disease
#5
Lingzhi Yuan, Dan Tang, Jin Peng, Nanfang Qu, Chun Yue, Fen Wang
To investigate the correlation between certain unhealthy lifestyles and the incidence of gastroesophageal reflux disease (GERD), thus to provide the lifestyle guidelines for GERD patients.
 Methods: Retrospective study were conducted for 402 GERD and 276 non-GERD out-patients in Department of Gastroenterology, Third Xiangya Hospital, Central South University from August, 2014 to August, 2015 based on questionnaire survey, then the correlation of unhealthy lifestyles with GERD were analyzed.
 Results: The top 10 common symptoms for GERD were as follows: reflux, acid regurgitation, postprandial fullness, heartburn, swallow obstruction or pain, epigastric burning sensation, paraesthesia pharynges, poststernal pain, chronic laryngopharyngitis, and chronic cough...
May 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28621269/tooth-wear-patterns-among-khat-and-shammah-users-in-jazan-city-kingdom-of-saudi-arabia-a-cross-sectional-survey
#6
Mohammed E Sayed, Ammar D Hamdi, Bassam M Hakami, Maryam H Mugri, Shilpa H Bhandi
AIM: The effect of Khat and Shammah habits, with the para-functional jaw activities that accompany them, on the structure and integrity of the natural dentition has not yet been investigated. The literature lacks studies that identify the patterns of tooth wear among Khat and Shammah users. Therefore, this study is the first attempt to address this concern in Jazan City population, Kingdom of Saudi Arabia. MATERIALS AND METHODS: A cross-sectional survey study was conducted among 300 recruits among dental clinics in Jazan City, Kingdom of Saudi Arabia from October 1, 2015, to April 30, 2016...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28612059/endoscopic-injection-therapy
#7
REVIEW
Sang Woon Kim, Yong Seung Lee, Sang Won Han
Since the U.S. Food and Drug Administration approved dextranomer/hyaluronic acid copolymer (Deflux) for the treatment of vesicoureteral reflux, endoscopic injection therapy using Deflux has become a popular alternative to open surgery and continuous antibiotic prophylaxis. Endoscopic correction with Deflux is minimally invasive, well tolerated, and provides cure rates approaching those of open surgery (i.e., approximately 80% in several studies). However, in recent years a less stringent approach to evaluating urinary tract infections (UTIs) and concerns about long-term efficacy and complications associated with endoscopic injection have limited the use of this therapy...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28612057/imaging-studies-and-biomarkers-to-detect-clinically-meaningful-vesicoureteral-reflux
#8
REVIEW
Michaella Maloney Prasad, Earl Y Cheng
The work-up of a febrile urinary tract infection is generally performed to detect vesicoureteral reflux (VUR) and its possible complications. The imaging modalities most commonly used for this purpose are renal-bladder ultrasound, voiding cystourethrogram and dimercapto-succinic acid scan. These studies each contribute valuable information, but carry individual benefits and limitations that may impact their efficacy. Biochemical markers are not commonly used in pediatric urology to diagnose or differentiate high-risk disease, but this is the emerging frontier, which will hopefully change our approach to VUR in the future...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28612056/critical-appraisal-of-the-top-down-approach-for-vesicoureteral-reflux
#9
REVIEW
Ahmed Abdelhalim, Antoine E Khoury
Vesicoureteral reflux (VUR) has been linked to recurrent urinary tract infections (UTIs), renal scarring, hypertension, renal insufficiency and end-stage kidney disease. Different imaging strategies have been proposed to approach children presenting with UTI to sort out patients with significant VUR while minimizing patient morbidity, radiation exposure and financial burden. None of these imaging strategies is universally accepted. The"top-down approach" (TDA) aims at restricting the number of voiding cystourethrograms (VCUGs) and its associated morbidity while identifying patients with clinically-significant reflux...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28607648/the-treatment-of-vesicoureteral-reflux-in-children-by-endoscopic-sub-mucosal-intra-ureteral-injection-of-dextranomer-hyaluronic-acid-a-case-series-multi-centre-study
#10
Osama Bawazir
BACKGROUND: Vesicoureteral reflux is a risk factor for progressive renal damage. In addition to long-term antibiotic prophylaxis and open surgical re-implantation, endoscopic sub-mucosal intra-ureteral injection of implant material is a therapeutic alternative that gained a world-wide preference. OBJECTIVE: The aim of this study was to determine the effectiveness and safety of the implant material, dextranomer/hyaluronic acid, in a cohort of Saudi children with vesicoureteral reflux...
April 2017: Electronic Physician
https://www.readbyqxmd.com/read/28605121/do-laryngoscopic-findings-reflect-the-characteristics-of-reflux-in-patients-with-laryngopharyngeal-reflux
#11
Y C Lee, O E Kwon, J M Park, Y G Eun
OBJECTIVE: To analyze the association between 24-hour multichannel intraluminal impedance-pH (24h MII-pH) parameters and each item of the reflux finding score (RFS) to determine whether the laryngoscopic findings of the RFS could reflect the characteristics of reflux in patients with laryngopharyngeal reflux (LPR). STUDY DESIGN: Prospective cohort study. SETTINGS: Tertiary care referral medical center. PARTICIPANTS: Patients complaining of LPR symptoms were evaluated via a 24h MII-pH...
June 12, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28604876/topotactic-conversion-of-layered-silicate-rub-15-to-silica-sodalite-through-interlayer-condensation-in-n-methylformamide
#12
Masakazu Koike, Yusuke Asakura, Megumi Sugihara, Yoshiyuki Kuroda, Hidehiro Tsuzura, Hiroaki Wada, Atsushi Shimojima, Kazuyuki Kuroda
Silica sodalite was obtained using topotactic conversion of layered silicate RUB-15 through stepwise processes that consisted of the control of stacking sequence of the layers, interlayer condensation by refluxing, and elimination of intercalated guest species. The interlayer condensation of RUB-15, in which acetic acid was pre-intercalated between the layers to control the stacking sequence, afforded a sodalite framework containing organic guest species by refluxing in N-methylformamide (NMF). The pre-intercalated acetic acid molecules were largely replaced with NMF...
June 12, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28596691/nissen-fundoplication-vs-proton-pump-inhibitors-for-laryngopharyngeal-reflux-based-on-ph-monitoring-and-symptom-scale
#13
Chao Zhang, Zhi-Wei Hu, Chao Yan, Qiong Wu, Ji-Min Wu, Xing Du, Dian-Gang Liu, Tao Luo, Fei Li, Zhong-Gao Wang
AIM: To compare the outcomes between laparoscopic Nissen fundoplication (LNF) and proton pump inhibitors (PPIs) therapy in patients with laryngopharyngeal reflux (LPR) and type I hiatal hernia diagnosed by oropharyngeal pH-monitoring and symptom-scale assessment. METHODS: From February 2014 to January 2015, 70 patients who were diagnosed with LPR and type I hiatal hernia and referred for symptomatic assessment, oropharyngeal pH-monitoring, manometry, and gastrointestinal endoscopy were enrolled in this study...
May 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28596098/acoustic-analysis-of-voice-and-electroglottography-in-patients-with-laryngopharyngeal-reflux
#14
Daphne Anahit Morales Ramírez, Víctor Manuel Valadez Jiménez, Xochiquetzal Hernández López, Pablo Antonio Ysunza
BACKGROUND: Laryngopharyngeal reflux (LPR) refers to the flow of gastric acid content into the laryngopharynx. It has been reported that 10% of the patients consulting an otolaryngologist present with this condition. Signs of LPR can be identified during flexible or rigid laryngoscopy. The Voice Handicap Index (VHI) is a reliable tool for detecting the impact of voice disorders, and acoustic assessment of voice including acoustic analysis of voice (AAV) and electroglottography (EGG) provide objective data of voice production and voice disorders...
June 5, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28593183/columnar-metaplasia-in-three-types-of-surgical-mouse-models-of-esophageal-reflux
#15
Fabio Terabe, Susumu Aikou, Junko Aida, Nobutake Yamamichi, Michio Kaminishi, Kaiyo Takubo, Yasuyuki Seto, Sachiyo Nomura
BACKGROUND AND AIMS: Esophageal adenocarcinoma develops in the setting of gastroesophageal reflux and columnar metaplasia in distal esophagus. Columnar metaplasia arising in gastroesophageal reflux models has developed in rat; however, gastroesophageal reflux models in mice have not been well-characterized. METHODS: One hundred thirty-five C57Bl/6J mice aged 8 weeks old were divided into the following operations: esophagogastrojejunostomy (side-to-side) (EGJ), esophageal separation and esophagojejunostomy (end-to-side) (EJ), and EJ and gastrectomy (end-to-side) (EJ/TG)...
July 2017: Cellular and Molecular Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28581835/development-and-gamma-scintigraphy-evaluation-of-gastro-retentive-calcium-ion-based-oral-formulation-an-innovative-approach-for-the-management-of-gastro-oesophageal-reflux-disease-gerd
#16
Braj Gaurav Sharma, Kushagra Khanna, Neeraj Kumar, Dhruv K Nishad, Mitra Basu, Aseem Bhatnagar
Calcium chloride is an essential calcium channel agonist which plays an important role in the contraction of muscles by triggering calcium channel. First time hypothesized about its role in the treatment of GER (gastro-oesophageal reflux) and vomiting disorder due to its local action. There are two objectives covered in the present study as first, the development & optimization of floating formulation of calcium chloride and another objective was to evaluated optimized formulation through gamma scintigraphy in human subjects...
June 5, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28573368/how-common-is-depression-in-patients-with-polymyalgia-rheumatica
#17
Arani Vivekanantham, Milica Blagojevic-Bucknall, Kris Clarkson, John Belcher, Christian D Mallen, Samantha L Hider
Depression is common in inflammatory disorders such as rheumatoid arthritis and systemic lupus erythematosus and negatively impacts on outcomes. Given the long-term nature of polymyalgia rheumatica (PMR) and its glucocorticoid treatment, these patients may be at an increased risk of depression, although few studies exist to date. This study aimed to investigate the prevalence of, and factors associated with, depression in PMR patients. Prevalent PMR patients (with a first diagnostic code for PMR in the last 3 years) were mailed a postal questionnaire (n = 704) examining PMR symptoms, glucocorticoid use and patient reported comorbidities...
June 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28571591/dietary-inflammatory-index-and-risk-of-reflux-oesophagitis-barrett-s-oesophagus-and-oesophageal-adenocarcinoma-a-population-based-case-control-study
#18
Nitin Shivappa, James R Hebert, Lesley A Anderson, Martha J Shrubsole, Liam J Murray, Lauren B Getty, Helen G Coleman
The dietary inflammatory index (DIITM) is a novel composite score based on a range of nutrients and foods known to be associated with inflammation. DII scores have been linked to the risk of a number of cancers, including oesophageal squamous cell cancer and oesophageal adenocarcinoma (OAC). Given that OAC stems from acid reflux and that the oesophageal epithelium undergoes a metaplasia-dysplasia transition from the resulting inflammation, it is plausible that a high DII score (indicating a pro-inflammatory diet) may exacerbate risk of OAC and its precursor conditions...
June 2, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28571180/gastroesophageal-reflux-disease-and-its-association-with-body-mass-index-clinical-and-endoscopic-study
#19
Bhumika Vaishnav, Arvind Bamanikar, Pragati Maske, Anudeep Reddy, Sukanya Dasgupta
INTRODUCTION: Obesity is rapidly becoming a pandemic and poses a serious health risk to the individuals. Abdominal obesity is quite common in India and is a prime risk factor for diseases like diabetes, coronary artery disease, Gastroesophageal Reflux Disease (GERD), osteoarthritis etc. A complex and multifactorial aetiopathogenesis of GERD exists in presence of obesity. The current study focuses on high Body Mass Index (BMI), a marker of obesity, as a risk factor for GERD and aims for a better understanding of their complex association...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28569739/endoscopic-guided-measurement-of-mucosal-admittance-can-discriminate-gastroesophageal-reflux-disease-from-functional-heartburn
#20
Tomoaki Matsumura, Hideaki Ishigami, Mai Fujie, Takashi Taida, Shingo Kasamatsu, Kenichiro Okimoto, Keiko Saito, Daisuke Maruoka, Tomoo Nakagawa, Takeshi Suzuki, Tatsuro Katsuno, Makoto Arai
OBJECTIVES: A novel catheter that can measure mucosal admittance (MA), the inverse of impedance, was developed recently. In this pilot study, we aimed to clarify the usefulness of measuring MA for diagnosing gastroesophageal reflux disease (GERD). METHODS: We conducted two prospective studies. In the first study, esophageal MA was evaluated in 120 participants (24 with erosive esophagitis, 82 with heartburn but non-erosive esophagitis, and 14 healthy volunteers) and compared with the endoscopic findings...
June 1, 2017: Clinical and Translational Gastroenterology
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