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Transition to the work environment

Simone A Costa, Joseph R Simon, Miriam Amiram, Lei Tang, Stefan Zauscher, Eric M Brustad, Farren J Isaacs, Ashutosh Chilkoti
Hydrogel particles are versatile materials that provide exquisite, tunable control over the sequestration and delivery of materials in pharmaceutics, tissue engineering, and photonics. The favorable properties of hydrogel particles depend largely on their size, and particles ranging from nanometers to micrometers are used in different applications. Previous studies have only successfully fabricated these particles in one specific size regime and required a variety of materials and fabrication methods. A simple yet powerful system is developed to easily tune the size of polypeptide-based, thermoresponsive hydrogel particles, from the nano- to microscale, using a single starting material...
December 11, 2017: Advanced Materials
Kinga Gołąbek, Karolina A Tarach, Urszula Filek, Kinga Góra-Marek
In this work, the role of pore arrangement of 10-ring zeolites ZSM-5, TNU-9 and IM-5 on their catalytic properties in ethanol transformation were investigated. Among all the studied catalysts, the zeolite IM-5, characterized by limited 3-dimensionality, presented the highest conversion of ethanol and the highest yields of diethyl ether (DEE) and ethylene. The least active and selective to ethylene and C3+ products was zeolite TNU-9 with the largest cavities formed on the intersection of 10-ring channels. The catalysts varied, however, in lifetime, and their deactivation followed the order: IM-5>TNU-9>ZSM-5...
November 23, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Laura A Ridgley, Amy E Anderson, Arthur G Pratt
PURPOSE OF REVIEW: Rheumatoid arthritis is a systemic disease of evolving immune dysregulation that culminates in joint destruction and disability. The principle by which pro-inflammatory cytokines may be therapeutically targeted to abrogate disease is well established, but has yet to translate into reliable cures for patients. Emerging insights into cytokine-mediated pathobiology during rheumatoid arthritis development are reviewed, and their implications for future treatment strategies considered...
December 4, 2017: Current Opinion in Rheumatology
Susan Gilbert Hunt
BACKGROUND/AIM: Historically occupational therapy has evidenced a tenacity to adjust and adapt to societal changes. Currently in Australia we are in the midst of significant change in health, disability and aged care service delivery alongside increasing numbers of new graduates seeking employment. Both of these changes create challenges and opportunities for the profession. How the profession adjusts to new service delivery models and supports new graduates in this changing work environment will influence our future...
December 2017: Australian Occupational Therapy Journal
Marlène Karam, Isabelle Brault, Thérèse Van Durme, Jean Macq
BACKGROUND: Interprofessional and interorganizational collaboration have become important components of a well-functioning healthcare system, all the more so given limited financial resources, aging populations, and comorbid chronic diseases. The nursing role in working alongside other healthcare professionals is critical. By their leadership, nurses can create a culture that encourages values and role models that favour collaborative work within a team context. OBJECTIVES: To clarify the specific features of conceptual frameworks of interprofessional and interorganizational collaboration in the healthcare field...
November 11, 2017: International Journal of Nursing Studies
Tao Gao, Xiao Ji, Singyuk Hou, Xiulin Fan, Xiaogang Li, Chongying Yang, Fudong Han, Fei Wang, Jianjun Jiang, Kang Xu, Chunsheng Wang
Rechargeable magnesium/sulfur battery is of significant interest because its energy density (1700 Wh kg-1 and 3200 Wh L-1 ) is among the highest of all battery chemistries (lower than Li/O2 and Mg/O2 but comparable to Li/S), and Mg metal allows reversible operation (100% Coulombic efficiency) with no dendrite formation. This great promise is already justified in some early reports. However, lack of mechanistic study of sulfur reaction in the Mg cation environment has severely hindered our understanding and prevents effective measures for performance improvement...
November 30, 2017: Advanced Materials
Johan Tornmalm, Jerker Widengren
Transient state (TRAST) monitoring can determine population dynamics of long-lived, dark transient states of fluorescent molecules, detecting only the average fluorescence intensity from a sample, when subject to different excitation pulse trains. Like Fluorescence Correlation Spectroscopy (FCS), TRAST unites the detection sensitivity of fluorescence with the environmental sensitivity of long-lived non-fluorescent states, but does not rely on detection of stochastic fluorescence fluctuations from individual molecules...
November 24, 2017: Methods: a Companion to Methods in Enzymology
Cláudia Correia, Alexey Koshkin, Patrícia Duarte, Dongjian Hu, Madalena Carido, Maria J Sebastião, Patrícia Gomes-Alves, David A Elliott, Ibrahim Domian, Ana P Teixeira, Paula M Alves, Margarida Serra
Three-dimensional (3D) cultures of human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) hold great promise for drug discovery, providing a better approximation to the in vivo physiology over standard two-dimensional (2D) monolayer cultures. However, the transition of CM differentiation protocols from 2D to 3D cultures is not straightforward. In this work, we relied on the aggregation of hPSC-derived cardiac progenitors and their culture under agitated conditions to generate highly pure cardiomyocyte aggregates...
November 27, 2017: Biotechnology and Bioengineering
M S Santini, M S Fernández, R Cavia, O D Salomón
The aim of this work was to study the distribution of Phlebotominae (Diptera: Psycodidade) abundance in time and space in an area in northeastern Argentina with vector transmission of visceral and tegumentary leishmaniasis. For this, 51 households were selected using a 'worst scenario' criterion where one light trap was set during two consecutive nights in peridomiciles in the transitions between the four seasons, and the environment was surveyed simultaneously. The relationships of phlebotomine assemblage structure and the most abundant species with seasonality and environmental variables were evaluated using a canonical correspondence analysis and generalized linear mixed models, respectively...
November 27, 2017: Medical and Veterinary Entomology
Sven Karsten, Sergey I Bokarev, Saadullah G Aziz, Sergei D Ivanov, Oliver Kühn
Modern X-ray spectroscopy has proven itself as a robust tool for probing the electronic structure of atoms in complex environments. Despite working on energy scales that are much larger than those corresponding to nuclear motions, taking nuclear dynamics and the associated nuclear correlations into account may be of importance for X-ray spectroscopy. Recently, we have developed an efficient protocol to account for nuclear dynamics in X-ray absorption and resonant inelastic X-ray scattering spectra [Karsten et al...
June 14, 2017: Journal of Chemical Physics
M-N Vacheron, H Veyrat-Masson, E Wehbe
Psychiatric disorders (more specifically mood disorders and psychosis) represent the 1st cause of disability among young people. Unemployment rate between 75 to 95% for the person with schizophrenia. It is correlated to poor social integration and bad economic status, worse symptomatology loss of autonomy as well as global bad functioning. It is responsible of more than half of the overall cost of psychosis. The onset of most of psychiatric disorders occur between the age of 25 and 35 years old, a critical time in young adult life when they should build their professional as well as social future...
November 8, 2017: L'Encéphale
Yang Wang, Zhiwen Liu, Shaodong Ma
This paper proposes an unobtrusive blood pressure (BP) measurement system design with motion artifact (MA) compensation strategy as a potential surrogate to the traditional cuff-based sphygmomanometer for self-monitoring in less restricted environment. Approach: A dual-channel photoplethysmographic signal acquisition system is designed and implemented for the cuff-less BP measurement based on peripheral pulse transit time (PPTT) acquired from the forearm and wrist. Comprised of motion decision, singular spectrum analysis, PPTT calculation and BP measurement, a novel approach is proposed to realize BP measurement with suppressing MA interference...
November 9, 2017: Physiological Measurement
Jakub Kaminský, Jakub Chalupský, Petr Štěpánek, Jan Kříž, Petr Bouř
Absorption and magnetic circular dichroism (MCD) spectroscopies are powerful and simple methods to discriminate among various compounds. Polycyclic aromatic hydrocarbons provide particularly strong signal, which, for example, facilitates their detection in the environment. However, interpretation of the spectra is often based on quantum-chemical simulations, providing a limited precision only. In the present work, we use time-dependent density functional theory and complete active space second-order perturbation theories to understand spectral features observed in a series of naphthalene, anthracene, phenanthrene, and three larger compounds...
November 17, 2017: Journal of Physical Chemistry. A
Zijun Wang, Tim Senden, Andries Meijerink
The radiative transition probability is a fundamental property for optical transitions. Extensive research, theoretical and experimental, has been conducted to establish the relation between the photonic environment and electric dipole (ED) transition probabilities. Recent work shows that the nanocrystal (NC)-cavity model accurately describes the influence of the refractive index n on ED transition rates for emitters in NCs. For magnetic dipole (MD) transitions, theory predicts a simple n(3) dependence. However, experimental evidence is sparse and difficult to obtain...
November 8, 2017: Journal of Physical Chemistry Letters
Annamaria Di Fabio, Letizia Palazzeschi, Ornella Bucci
The twenty-first century is characterized by an unpredictable and challenging work environment, and the Intrapreneurial Self-Capital (ISC) career and life construct can be seen as a core of individual intrapreneurial resources that enables people to cope with ongoing challenges, changes, and transitions founding innovative solutions when confronted with the constraints imposed by such an environment. The ISC is a challenging construct since it can enhance behavior and attitudes through specific training, unlike personality traits, which are considered substantially stable in the literature...
2017: Frontiers in Psychology
W Michael Hooten, Chad M Brummett, Mark D Sullivan, Jenna Goesling, Jon C Tilburt, Jessica S Merlin, Jennifer L St Sauver, Ajay D Wasan, Daniel J Clauw, David O Warner
An urgent need exists to better understand the transition from short-term opioid use to unintended prolonged opioid use (UPOU). The purpose of this work is to propose a conceptual framework for understanding UPOU that posits the influence of 3 principal domains that include the characteristics of (1) individual patients, (2) the practice environment, and (3) opioid prescribers. Although no standardized method exists for developing a conceptual framework, the process often involves identifying corroborative evidence, leveraging expert opinion to identify factors for inclusion in the framework, and developing a graphic depiction of the relationships between the various factors and the clinical problem of interest...
December 2017: Mayo Clinic Proceedings
Ian S Barton, Clay Fuqua, Thomas G Platt
Many important pathogens maintain significant populations in highly disparate disease and non-disease environments. The consequences of this environmental heterogeneity in shaping the ecological and evolutionary dynamics of these facultative pathogens are incompletely understood. Agrobacterium tumefaciens, the causative agent for crown gall disease of plants has proven a productive model for many aspects of interactions between pathogens and their hosts and with other microbes. In this review, we highlight how this past work provides valuable context for the use of this system to examine how heterogeneity and transitions between disease and non-disease environments influence the ecology and evolution of facultative pathogens...
November 3, 2017: Environmental Microbiology
Frances E Hauser, Belinda Sw Chang
Sensory systems provide valuable insight into the evolution of molecular mechanisms underlying organismal anatomy, physiology, and behaviour. Visual pigments, which mediate the first step in visual transduction, offer a unique window into the relationship between molecular variation and visual performance, and enhance our understanding of how ecology, life history, and physiology may shape genetic variation across a variety of organisms. Here we review recent work investigating vertebrate visual pigments from a number of perspectives...
November 2, 2017: Current Opinion in Genetics & Development
Knut Rudi, Inga Leena Angell, Phillip B Pope, Jon Olav Vik, Simen Rød Sandve, Lars-Gustav Snipen
Gut microbiota associations through habitat transitions are fundamentally important, yet poorly understood. One such habitat transition is the migration from fresh to salt water for anadromous fish such as salmon. The aim of the current work was therefore to determine the fresh- to saltwater impact on the gut microbiota in farmed Atlantic salmon, with dietary interventions resembling that of fresh- and salt water diets with respect to fatty acid composition. Using deep 16S rRNA gene sequencing, and quantitative PCR, we found that the fresh- to salt water transition both had a major association with the microbiota composition and quantity, while diet did not show significantly associations with the microbiota...
November 3, 2017: Applied and Environmental Microbiology
Stijn Wielandt, Lieven De Strycker
Indoor radio frequency positioning systems enable a broad range of location aware applications. However, the localization accuracy is often impaired by Non-Line-Of-Sight (NLOS) connections and indoor multipath effects. An interesting evolution in widely deployed communication systems is the transition to multi-antenna devices with beamforming capabilities. These properties form an opportunity for localization methods based on Angle of Arrival (AoA) estimation. This work investigates how multipath propagation can be exploited to enhance the accuracy of AoA localization systems...
November 2, 2017: Sensors
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