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https://www.readbyqxmd.com/read/29036459/the-multiple-facets-of-root-iron-reduction
#1
Louis Grillet, Wolfgang Schmidt
The biological significance of iron (Fe) is based on its propensity to oscillate between the ferric and ferrous forms, a transition that also affects its phyto-availability in soils. With the exception of grasses, Fe3+ is unavailable to plants. Most angiosperms employ a reduction-based Fe uptake mechanism, which relies on enzymatic reduction of ferric iron as an obligatory, rate-limiting step prior to uptake. This system functions optimally in acidic soils. Calcicole plants are, however, exposed to environments that are alkaline and/or have suboptimal availability of phosphorous, conditions under which the enzymatic reduction mechanism ceases to work effectively...
September 25, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29035073/contextual-cueing-of-tactile-search-is-coded-in-an-anatomical-reference-frame
#2
Leonardo Assumpção, Zhuanghua Shi, Xuelian Zang, Hermann J Müller, Thomas Geyer
This work investigates the reference frame(s) underlying tactile context memory, a form of statistical learning in a tactile (finger) search task. In this task, if a searched-for target object is repeatedly encountered within a stable spatial arrangement of task-irrelevant distractors, detecting the target becomes more efficient over time (relative to nonrepeated arrangements), as learned target-distractor spatial associations come to guide tactile search, thus cueing attention to the target location. Since tactile search displays can be represented in several reference frames, including multiple external and an anatomical frame, in Experiment 1 we asked whether repeated search displays are represented in tactile memory with reference to an environment-centered or anatomical reference frame...
October 16, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/29033929/immunity-and-fibrogenesis-the-role-of-th17-il-17-axis-in-hbv-and-hcv-induced-chronic-hepatitis-and-progression-to-cirrhosis
#3
REVIEW
Feliciano Chanana Paquissi
Cirrhosis is a common final pathway for most chronic liver diseases; representing an increasing burden worldwide and is associated with increased morbidity and mortality. Current evidence has shown that, after an initial injury, the immune response has a significant participation in the ongoing damage, and progression from chronic viral hepatitis (CVH) to cirrhosis, driving the activation and maintenance of main fibrogenic pathways. Among immune deregulations, those related to the subtype 17 of T helper lymphocytes (Th17)/interleukin-17 (IL-17) axis have been recognized as key immunopathological and prognostic elements in patients with CVH...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29033886/complex-problem-solving-in-teams-the-impact-of-collective-orientation-on-team-process-demands
#4
Vera Hagemann, Annette Kluge
Complex problem solving is challenging and a high-level cognitive process for individuals. When analyzing complex problem solving in teams, an additional, new dimension has to be considered, as teamwork processes increase the requirements already put on individual team members. After introducing an idealized teamwork process model, that complex problem solving teams pass through, and integrating the relevant teamwork skills for interdependently working teams into the model and combining it with the four kinds of team processes (transition, action, interpersonal, and learning processes), the paper demonstrates the importance of fulfilling team process demands for successful complex problem solving within teams...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29032292/glimpses-into-the-transition-world-new-graduate-nurses-written-reflections
#5
Jo Ann Walton, Natalie Lindsay, Caz Hales, Helen Rook
BACKGROUND: This study was born out of our reflections as educators responsible for helping new graduate nurses transition into their first year of professional practice through a formal education programme. Finding ourselves wondering about many of the questions the students raised with us, we set about looking more closely at what could be gleaned from the students' experience, captured in their written work over the course of a year. OBJECTIVES: To identify the challenges and learning experiences revealed in reflective assignments written by new graduate nurses undertaking a postgraduate course as part of their transition to registered nurse practice...
October 6, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29031469/gunslingers-poker-players-and-chickens-2-decision-making-under-physical-performance-pressure-in-subelite-athletes
#6
Beth L Parkin, Vincent Walsh
BACKGROUND: Having investigated the influence of acute physical exhaustion on decision-making in world-class elite athletes in Parkin et al. (2017), here a similar method is applied to subelite athletes. These subelite athletes were enrolled on a Team GB talent development program and were undergoing training for possible Olympic competition in 4-8 years. They differ from elite athletes examined previously according to expertise and age. While considered elite (Swann et al., 2015), the subelite athletes had approximately 8 years fewer sporting experience and were yet to obtain sustained success on the international stage...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29021552/lifshitz-transition-from-valence-fluctuations-in-ybal3
#7
Shouvik Chatterjee, Jacob P Ruf, Haofei I Wei, Kenneth D Finkelstein, Darrell G Schlom, Kyle M Shen
In mixed-valent Kondo lattice systems, such as YbAl3, interactions between localized and delocalized electrons can lead to fluctuations between two different valence configurations with changing temperature or pressure. The impact of this change on the momentum-space electronic structure is essential for understanding their emergent properties, but has remained enigmatic. Here, by employing a combination of molecular beam epitaxy and in situ angle-resolved photoemission spectroscopy we show that valence fluctuations can lead to dramatic changes in the Fermi surface topology, even resulting in a Lifshitz transition...
October 11, 2017: Nature Communications
https://www.readbyqxmd.com/read/28976238/the-response-of-soil-arthrobacter-agilis-lush13-to-changing-conditions-transition-between-vegetative-and-dormant-state
#8
Inna P Solyanikova, Nataliya E Suzina, Nataliya S Egozarian, Valentina N Polivtseva, Nataliya V Prisyazhnaya, Galina I El-Registan, Andrey L Mulyukin, Ludmila A Golovleva
This work was aimed at studying the response of soil non-spore-forming actinobacterial strain Arthrobacter agilis Lush 13 to changing natural conditions, such as nutrient availability and the presence of degradable and recalcitrant aliphatic and aromatic substrates. The A. agilis strain Lush13 was able to degrade octane, nonane, hexadecane, benzoate, phenol, and 2,3-, 2,4-, 2,5-, 2,6-dichlorophenols, but not grew on 3,4-dichlorophenol, 2,3,4-, 2,4,5-, 2,4,6-trichlorophenol (TCP), pentachlorophenol (PCP), 2-chlorobenzoate, 3-chlorobenzoate, 3,5-dichlorobenzoate, 2,4-dichlorobenzoate...
October 4, 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/28973181/scholar-7-the-development-of-regional-community-hospitals-scholastic-environment
#9
Brian P Peppers, Priya Varma, Yoon Mi Kim, Robert W Hostoffer, Michael P Rowane
The importance of increasing scholarly activity has been highlighted among residency programs currently accredited by the American Osteopathic Association (AOA) to ensure a smooth transition to the single accreditation system. The Scholar 7 program, a series of seven 2-hour sessions, was created to aid faculty and residents in the pursuit of scholarly work and to facilitate change in an entire community hospital system's environment by creating a self-replicating scholarly culture in a timely and cost-efficient manner...
October 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28954184/long-term-care-nurse-residency-program-evaluation-of-new-nurse-experiences-and-lessons-learned
#10
Susan W Salmond, Edna Cadmus, Katherine Kuren Black, Nancy Bohnarczyk, Linda Hassler
Transitioning to long-term care environments presents a significant challenge for new nurses and their directors of nursing. The complexity of this environment, instability of the workforce, and the lack of support structures frequently affect a new nurse's decision not to apply to long-term care, but to look for positions in acute care hospitals. To address these issues, a long-term care new nurse residency program was developed, implemented, and evaluated in New Jersey through the work of the New Jersey Action Coalition...
October 1, 2017: Journal of Continuing Education in Nursing
https://www.readbyqxmd.com/read/28954049/knowledge-attitudes-and-practices-of-women-farmers-concerning-tobacco-agriculture-in-a-municipality-in-southern-brazil
#11
Marcelo Moreno Dos Reis, Ana Paula Natividade de Oliveira, Silvana Rubano Barretto Turci, Renato Maciel Dantas, Valéria Dos Santos Pinto da Silva, Cátia Gross, Teresinha Jensen, Vera Luiza da Costa E Silva
The study aimed to explore the knowledge, attitudes, and practices of women farmers working in tobacco production concerning the social, environmental, and health impacts of this economic activity. Focus groups were used in this qualitative study, and themes were explored until reaching saturation. The study was conducted in a municipality (county) in southern Brazil in 2013 and included 64 women farmers. The discussions revealed participants' familiarity with health problems associated with workloads in tobacco production: green tobacco sickness, pesticide poisoning, musculoskeletal disorders, and others...
September 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28953056/how-nurse-work-environments-relate-to-the-presence-of-parents-in-neonatal-intensive-care
#12
Sunny G Hallowell, Jeannette A Rogowski, Eileen T Lake
BACKGROUND: Parental presence in the neonatal intensive care unit (NICU) is essential for families to participate in infant care and prepare them to transition from hospital to home. Nurses are the principal caregivers in the NICU. The nurse work environment may influence whether parents spend time with their hospitalized infants. PURPOSE: To examine the relationship between the NICU work environment and parental presence in the NICU using a national data set. METHODS: We conducted a cross-sectional, observational study of a national sample of 104 NICUs, where 6060 nurses reported on 15,233 infants cared for...
September 25, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28952626/aqueous-chemistry-of-ce-iv-estimations-using-actinide-analogues
#13
Rémi Marsac, Florent Réal, Nidhu Lal Banik, Mathieu Pédrot, Olivier Pourret, Valérie Vallet
The prediction of cerium (Ce) aqueous speciation is relevant in many research fields. Indeed, Ce compounds are used for many industrial applications, which may require the control of Ce aqueous chemistry for their synthesis. The aquatic geochemistry of Ce is also of interest. Due to its growing industrial use and its release into the environment, Ce is now considered as an emerging contaminant. Cerium is also used as a proxy of (paleo)redox conditions due to the Ce(iv)/Ce(iii) redox transition. Finally, Ce(iv) is often presented as a relevant analogue of tetravalent actinides (An(iv))...
October 10, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28951887/proteomes-of-lactobacillus-delbrueckii-subsp-bulgaricus-lbb-b5-incubated-in-milk-at-optimal-and-low-temperatures
#14
Xiaochen Yin, Michelle R Salemi, Brett S Phinney, Velitchka Gotcheva, Angel Angelov, Maria L Marco
We identified the proteins synthesized by Lactobacillus delbrueckii subsp. bulgaricus strain LBB.B5 in laboratory culture medium (MRS) at 37°C and milk at 37 and 4°C. Cell-associated proteins were measured by gel-free, shotgun proteomics using high-performance liquid chromatography coupled with tandem mass spectrophotometry. A total of 635 proteins were recovered from all cultures, among which 72 proteins were milk associated (unique or significantly more abundant in milk). LBB.B5 responded to milk by increasing the production of proteins required for purine biosynthesis, carbohydrate metabolism (LacZ and ManM), energy metabolism (TpiA, PgK, Eno, SdhA, and GapN), amino acid synthesis (MetE, CysK, LBU0412, and AspC) and transport (GlnM and GlnP), and stress response (Trx, MsrA, MecA, and SmpB)...
September 2017: MSystems
https://www.readbyqxmd.com/read/28934270/assessment-of-the-trophic-state-of-a-hypersaline-carbonatic-environment-vermelha-lagoon-brazil
#15
Lazaro Laut, Maria Virginia Alves Martins, Fabrizio Frontalini, João M Ballalai, Pierre Belart, Renan Habib, Luiz F Fontana, Iara M M M Clemente, Maria Lucia Lorini, João G Mendonça Filho, Vanessa M Laut, Marcos de Souza Lima Figueiredo
Vermelha Lagoon is a hypersaline shallow transitional ecosystem in the state of Rio de Janeiro (Brazil). This lagoon is located in the protected area of Massambaba, between the cities of Araruama and Saquarema (Brazil), and displays two quite uncommon particularities: it exhibits carbonate sedimentation and displays the development of Holocene stromatolites. Due to both particularities, the salt industry and property speculation have been, increasingly, generating anthropic pressures on this ecosystem. This study aims to apply a multiproxy approach to evaluate the trophic state of Vermelha Lagoon based on physicochemical parameters and geochemical data for the quantification and qualification of organic matter (OM), namely total organic carbon (TOC), total sulfur (TS), total phosphorus (TP) and biopolymeric carbon (BPC), including carbohydrates (CHO), lipids (LIP) and proteins (PTN)...
2017: PloS One
https://www.readbyqxmd.com/read/28924965/comparative-studies-of-cellular-viability-levels-on-2d-and-3d-in-vitro-culture-matrices
#16
M Gargotti, U Lopez-Gonzalez, H J Byrne, A Casey
In this study, the cellular viability and function of immortalized human cervical and dermal cells are monitored and compared in conventional 2D and two commercial 3D membranes, Collagen and Geltrex, of varying working concentration and volume. Viability was monitored with the aid of the Alamar Blue assay, cellular morphology was monitored with confocal microscopy, and cell cycle studies and cell death mechanism studies were performed with flow cytometry. The viability studies showed apparent differences between the 2D and 3D culture systems, the differences attributed in part to the physical transition from 2D to 3D environment causing alterations to effective resazurin concentration, uptake and conversion rates, which was dependent on exposure time, but also due to the effect of the membrane itself on cellular function...
September 18, 2017: Cytotechnology
https://www.readbyqxmd.com/read/28921049/the-association-between-exposure-to-psychosocial-work-factors-and-mental-health-in-older-employees-a-3-year-follow-up-study
#17
Bo M Havermans, Cécile R L Boot, Trynke Hoekstra, Irene L D Houtman, Evelien P M Brouwers, Johannes R Anema, Allard J van der Beek
PURPOSE: Unfavourable exposure to psychosocial work factors threatens older employees' mental health, and their sustained employment. This study assesses whether an improved compared to stable unfavourable and stable favourable exposure to psychosocial work factors is associated with a change in mental health in older employees at 3-year follow-up. METHODS: The current study used data from the Study on Transitions in Employment, Ability and Motivation (STREAM), in workers aged 45-65 years (n = 5249)...
September 18, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28912886/the-ph-triggered-triblock-nanocarrier-enabled-highly-efficient-sirna-delivery-for-cancer-therapy
#18
Lili Du, Junhui Zhou, Lingwei Meng, Xiaoxia Wang, Changrong Wang, Yuanyu Huang, Shuquan Zheng, Liandong Deng, Huiqing Cao, Zicai Liang, Anjie Dong, Qiang Cheng
Small interfering RNA (siRNA) therapies have been hampered by lack of delivery systems in the past decades. Nowadays, a few promising vehicles for siRNA delivery have been developed and it is gradually revealed that enhancing siRNA release from endosomes into cytosol is a very important factor for successful delivery. Here, we designed a novel pH-sensitive nanomicelle, PEG-PTTMA-P(GMA-S-DMA) (PTMS), for siRNA delivery. Owing to rapid hydrolysis in acidic environment, PTMS NPs underwent hydrophobic-to-hydrophilic transition in endosomes that enabled combination of proton sponge effect and raised osmotic pressure in endosomes, resulting in vigorous release of siRNAs from endosomes into cytosol...
2017: Theranostics
https://www.readbyqxmd.com/read/28895722/dielectric-sphere-clusters-as-a-model-to-understand-infrared-spectroscopic-imaging-data-recorded-from-complex-samples
#19
Ilia L Rasskazov, Nicolas Spegazzini, P Scott Carney, Rohit Bhargava
Understanding the infrared (IR) spectral response of materials as a function of their morphology is not only of fundamental importance but also of contemporary practical need in the analysis of biological and synthetic materials. While significant work has recently been reported in understanding the spectra of particles with well-defined geometries, we report here on samples that consist of collections of particles. First, we theoretically model the importance of multiple scattering effects and computationally predict the impact of local particles' environment on the recorded IR spectra...
October 17, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28894935/tissue-compartmentalization-of-t-cell-responses-during-early-life
#20
REVIEW
Kyra D Zens, Thomas Connors, Donna L Farber
The immune system in early life is tasked with transitioning from a relatively protected environment to one in which it encounters a wide variety of innocuous antigens and dangerous pathogens. The immaturity of the developing immune system, and particularly the distinct functionality of T lymphocytes in early life, has been implicated in increased susceptibility to infection. Previous work has demonstrated that immune responses in early life are skewed toward limited inflammation and atopy; however, there is mounting evidence that such responses are context- and tissue-dependent...
September 11, 2017: Seminars in Immunopathology
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