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https://www.readbyqxmd.com/read/29334213/conservative-management-of-ovarian-fibroma-in-a-case-of-gorlin-goltz-syndrome-comorbid-with-endometriosis
#1
Sepideh Khodaverdi, Leila Nazari, Abolfazl Mehdizadeh-Kashi, Mansoureh Vahdat, Samaneh Rokhgireh, Ali Farbod, Banafsheh Tajbakhsh
Ovarian fibromas are the most common benign solid ovarian tumors, which are often difficult to diagnose preoperatively. Ovarian fibromas, especially in bilateral cases, may be cases of Gorlin-Goltz syndrome (GGS), a rare autosomal dominant disorder with predisposition to basal cell carcinomas (BCCs) and other various benign and malignant tumors. This case report describes a 25 year-old female with GGS, bilateral ovarian fibroma, endometriosis and septated uterus, which was referred to the Gynecology Clinic of Rasoul-e-Akram Hospital in October 2016...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29332562/the-delicate-balance-between-the-good-and-the-bad-il-1-proinflammatory-effects-in-endometriosis
#2
Justyna Sikora, Simone Ferrero, Aleksandra Mielczarek-Palacz, Zdzislawa Kondera-Anasz
BACKGROUND: Endometriosis is an inflammatory gynaecological disease with an associated chronic inflammation. Interleukin(IL)-1 is one of the most important immune and proinflammatory factors, produced mainly by monocytes and macrophages. Studies indicate the role of the cytokine from IL-1 family in endometrium-related disorders, particularly in endometriosis. METHODS: The information about the impact of cytokine from IL-1 cytokine family on the pathogenesis and development of endometriosis was obtained with an electronic literature search based on the PubMed and Medline databases, spanning the period of January 1950 to July 2017 and includes associated references in the published studies...
January 10, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29332404/bowel-obstruction-secondary-to-deep-infiltrating-endometriosis-of-the-ileum
#3
Marco Antonio Ávila Vergara, Violeta Sánchez Carrillo, Felipe Peraza Garay
Deep infiltrating endometriosis (DIE) of the ileum is an uncommon lesion that may be severe in its clinical presentation. Its diagnosis is challenging in the absence of a gynecological history of endometriosis and because of its anatomical location. We read the article by Sánchez, Candel, and Albarracín, and now report an additional case that was managed urgently.
January 15, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29332362/association-of-non-hodgkin-s-lymphoma-with-advanced-endometriosis
#4
Michail Matalliotakis, Artemis Pontikaki, Athina E Patelarou, Stefanos Zervoudis, Aydin Arici
No abstract text is available yet for this article.
November 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29330150/dysfunctional-signaling-underlying-endometriosis-current-state-of-knowledge
#5
Yeon Jean Cho, Seung Hyun Lee, Jung Woo Park, Myoungseok Han, Mi Jin Park, Sang Jun Han
Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. It affects approximately 5-10% of women of reproductive age. Endometriosis is associated with dysmenorrhea, dyspareunia and, often, severe pelvic pain. In addition to pain, women with endometriosis often experience infertility. Defining the molecular etiology of endometriosis is a significant challenge for improving the quality of women's lives. Unfortunately, the pathophysiology of endometriosis is not well understood...
January 12, 2018: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/29328375/the-role-of-il%C3%A2-16-gene-polymorphisms-in-endometriosis
#6
Michail Matalliotakis, Maria I Zervou, Elias Eliopoulos, Charoula Matalliotaki, Nilufer Rahmioglu, Ioannis Kalogiannidis, Krina Zondervan, Demetrios A Spandidos, Ioannis Matalliotakis, George N Goulielmos
Endometriosis is one of the most common gynecological diseases affecting up to 10% of the female population of childbearing age and a major cause of pain and infertility. It is influenced by multiple genetic, epigenetic and environmental factors. Interleukin‑16 (IL‑16) is a proinflammatory cytokine playing a pivotal role in many inflammatory and autoimmune diseases as well as in the pathogenesis of endometriosis. The aim of the present study was to evaluate the association of two IL‑16 gene single nucleotide polymorphisms (SNPs), rs4072111 and rs11556218, with the risk of endometriosis in women from Greece as well as to gain insight about the structural consequences of these two exonic SNPs regarding development of the disease...
January 9, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29328022/-endometriosis-a-new-approach-to-etiology-and-pathogenesis-review
#7
A Solopova, A Makacarya, E Chukanova
Endometriosis is a dyshormonal immune-dependent genetically determined disease, which appears as an endometrioid tissue that grows outside the uterine. Endometriosis is one of the most urgent problems of medicine. To date, new concepts of the endometriosis etiology and pathogenesis have been developed, but, despite their abundance, there is no unified theory. Genetic and epigenetic factors result in changes in an expression of aromatase, steroidogenic factor 1, and estrogen receptors are suggested to be the main cause of endometriosis...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29327861/prognostic-factors-in-intrauterine-insemination-cycles
#8
Fernanda Sicchieri, Aline Bomfim Silva, Ana Carolina Japur de Sá Rosa E Silva, Paula Andrea de Albuquerque Sales Navarro, Rui Alberto Ferriani, Rosana Maria Dos Reis
OBJECTIVE: This study aimed to evaluate the clinical pregnancy rate of intrauterine insemination cycles in relation to patient age, cause of infertility, ovulation induction method, number of mature follicles and sperm with progressive motility. METHODS: This retrospective observational study included 237 intrauterine insemination cycles performed from 2011 to 2015 at the Assisted Reproduction Service of the Hospital das Clínicas of the Ribeirão Preto Medical School, University of São Paulo...
January 12, 2018: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29325269/-research-progress-of-brain-derived-neurotrophic-factor-in-the-pain-of-endometriosis
#9
(no author information available yet)
No abstract text is available yet for this article.
December 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29320955/therapeutic-roles-of-statins-in-gynecology-and-obstetrics-the-current-evidence
#10
Burak Zeybek, Maged Costantine, Gokhan S Kilic, Mostafa A Borahay
INTRODUCTION: Statins are a class of drugs, which act by inhibiting the rate-limiting enzyme of cholesterol biosynthesis (3-hydroxy-3-methyl-glutaryl-CoA reductase). The inhibition of mevalonate synthesis leads to subsequent inhibition of downstream products of this pathway, which explains the pleiotropic effects of these agents in addition to their well-known lipid-lowering effects. Accumulating evidence suggests that statins might be beneficial in various obstetric and gynecologic conditions...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29320327/atypical-sites-of-deeply-infiltrative-endometriosis-clinical-characteristics-and-imaging-findings
#11
Luciana P Chamié, Duarte Miguel Ferreira Rodrigues Ribeiro, Dario A Tiferes, Augusto Cesar de Macedo Neto, Paulo C Serafini
Endometriosis is defined as the presence of endometrial tissue that is located outside the uterine cavity and associated with fibrosis and inflammatory reaction. It is a polymorphic and multifocal disease with no known cure or preventive mechanisms. Patients may be asymptomatic or may experience chronic pelvic pain, dysmenorrhea, dyspareunia, or infertility. The pelvic cavity is the most common location for endometriotic implants, which usually affect the retrocervical space, ovaries, vagina, rectosigmoid colon, bladder dome, and round ligaments...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29318892/transplantation-of-cryopreserved-ovarian-tissue-in-a-patient-affected-by-metastatic-struma-ovarii-and-endometriosis
#12
Raffaella Fabbri, Rossella Vicenti, Roberto Paradisi, Stefania Rossi, Lucia De Meis, Renato Seracchioli, Maria Macciocca
In this case report, the outcomes of cryopreserved ovarian tissue transplantation performed in a patient affected by struma-ovarii associated with mature cystic teratoma, recurrent endometriotic cysts and diffuse peritoneal malignant struma-ovarii implants were described. Before cryopreservation, the patient underwent two left ovarian surgeries for enucleation cysts 8 years after righ salpingo-oophorectomy for struma-ovarii. Ovarian biopsy was collected in another hospital and transported to our laboratory for cryopreservation...
January 10, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29318645/endometriosis-increased-the-risk-of-bladder-pain-syndrome-interstitial-cystitis-a-population-based-study
#13
Chia-Chang Wu, Shiu-Dong Chung, Herng-Ching Lin
OBJECTIVE: Previous studies have suggested an association between bladder pain syndrome/interstitial cystitis (BPS/IC) and endometriosis. However, no nation-wide population study has yet reported an association between them. In this study, we examined the risk of BPS/IC among subjects with endometriosis during a 3-year follow-up in Taiwan using a population-based dataset. STUDY DESIGN: This study comprised 9191 subjects with endometriosis, and 27 573 subjects randomly selected as controls...
January 10, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29317075/the-origin-of-endometriosis-associated-ovarian-cancer-from-uterine-neoplastic-lesions
#14
Elisabetta Garavaglia, Cristina Sigismondi, Stefano Ferrari, Massimo Candiani
Endometriosis is a risk factor for type I epithelial ovarian cancer but an issue to be clarified is the site of origin of endometriosis associated ovarian cancer. Here we proposed that the uterus may be the organ of origin of ovarian endometrioid cancer associated with endometriosis. Thus, the first neoplastic transformation would characterize the uterine cells migrating in the pelvis via retrograde menstruation and they would implant secondarily on the ovary. Supporting this hypothesis, an higher incidence of synchronous precancerous and cancerous endometrial pathology in patients affected by ovarian endometrioid cancer associated with endometriosis was showed...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29316321/the-role-of-peritoneal-washings-in-the-diagnosis-of-endometriosis
#15
Richard L Cantley, Lorene Yoxtheimer, Stacy Molnar
Endometriosis, the presence of endometrial tissue outside the uterine corpus, is a common finding in reproductive age women. It is classically diagnosed based on the presence of at least two of the following elements: endometrial glands, endometrial stroma, and hemosiderin-laden macrophages (HLMs). Although a common finding in surgical pathology specimens at the time of gynecologic surgery, there is little literature on the role of pelvic washings in diagnosing endometriosis. Our study aimed to examine the characteristics of endometriosis in pelvic washings at the time of gynecologic surgery...
January 8, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29316073/involvement-of-immune-cells-in-the-pathogenesis-of-endometriosis
#16
Gentaro Izumi, Kaori Koga, Masashi Takamura, Tomoko Makabe, Erina Satake, Arisa Takeuchi, Ayumi Taguchi, Yoko Urata, Tomoyuki Fujii, Yutaka Osuga
Endometriosis is characterized by the implantation and growth of endometriotic tissues outside the uterus. It is widely accepted the theory that endometriosis is caused by the implantation of endometrial tissue from retrograde menstruation; however, retrograde menstruation occurs in almost all women and other factors are required for the establishment of endometriosis, such as cell survival, cell invasion, angiogenesis, and cell growth. Immune factors in the local environment may, therefore, contribute to the formation and progression of endometriosis...
January 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29316041/bilateral-tubo-ovarian-abscesses-presenting-with-huge-pelvic-mass-after-repeated-intrauterine-inseminations-in-a-woman-with-severe-endometriosis
#17
Patsama Vichinsartvichai
A 32-year-old woman consulted for an evaluation of pelvic pain following intrauterine insemination (IUI). Vaginal and abdominal sonography, septic workup were performed and laparoscopic surgery was scheduled after failure to respond to a course of antibiotics. During laparoscopic surgery, bilateral tubo-ovarian abscesses arising on the endometriotic cysts of both ovaries were identified with a vast amount of brownish peritoneal fluid under the adhesion of the greater omentum. Bilateral ovarian cystectomy, right salpingectomy and lysis adhesion were performed...
January 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29315418/fertility-outcomes-in-women-experiencing-severe-complications-after-surgery-for-colorectal-endometriosis
#18
C Ferrier, H Roman, Y Alzahrani, E Mathieu d'Argent, S Bendifallah, N Marty, M Perez, C Rubod, P Collinet, E Daraï, M Ballester
STUDY QUESTION: What are the fertility outcomes in women wishing to conceive after experiencing a severe complication from surgical removal of colorectal endometriosis? SUMMARY ANSWER: The pregnancy rate (PR) among women who wished to conceive after a severe complication of surgery for colorectal endometriosis was 41.2% (spontaneously for 80%, after ART procedure for 20%). WHAT IS KNOWN ALREADY: While the long-term benefit of surgery on pain and quality of life is well documented for women with colorectal endometriosis, it exposes women to the risk of severe complications...
January 5, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29313088/urodynamic-observations-and-lower-urinary-tract-symptoms-associated-with-endometriosis-a-prospective-cross-sectional-observational-study-assessing-women-with-deep-infiltrating-disease
#19
José Anacleto Dutra de Resende Júnior, Claudio Peixoto Crispi, Leon Cardeman, Renata Teles Buere, Márlon de Freitas Fonseca
INTRODUCTION AND HYPOTHESIS: The objective was to assess the association between lower urinary tract disease (LUTD) and the presence of endometriosis at different anatomical sites. METHODS: Our prospective cross-sectional observational study evaluated 138 women with deep infiltrating endometriosis who had undergone preoperative evaluation of urodynamics and detailed assessment of lower urinary tract symptoms between August 2013 and May 2016. After laparoscopy, the anatomical sites of histologically confirmed endometriosis lesions were mapped...
January 8, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29310043/cutaneous-endometriosis-presentation-of-33-cases-and-literature-review
#20
Alvaro Lopez-Soto, Maria Isabel Sanchez-Zapata, Juan Pedro Martinez-Cendan, Sebastian Ortiz Reina, Carmen Maria Bernal Mañas, Manuel Remezal Solano
OBJECTIVE: Cutaneous endometriosis is a rare condition that usually affects the abdominal wall in women with a history of open abdominal surgery. It has a characteristic clinical picture of a mass and pain associated with menstruation. The diagnosis is difficult on being an uncommon and little known condition. Once there is suspicion, a correct anamnesis and examination is usually sufficient. The treatment is normally surgery. STUDY DESIGN: The study included all women identified with a diagnosis of cutaneous endometriosis over a period of 20 years...
December 7, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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