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https://www.readbyqxmd.com/read/28110201/influence-of-soil-types-and-osmotic-pressure-on-growth-and-137-cs-accumulation-in-blackgram-vigna-mungo-l
#1
Khin Thuzar Win, Aung Zaw Oo, Sonoko Dorothea Bellingrath-Kimura
A pot experiment was conducted to study the effects of soil types and osmotic levels on growth and (137)Cs accumulation in two blackgram varieties differing in salinity tolerance grown in Fukushima contaminated soils. The contamination levels of the sandy clay loam and clay soil were 1084 and 2046 Bq kg(-1) DW, respectively. The (137)Cs activity was higher in both plants grown on the sandy clay loam than on the clay soil regardless of soil (137)Cs activity concentration. No significant differences were observed in all measured growth parameters between the two varieties under optimal water conditions for both types of soil...
January 19, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28110170/tailoring-polymeric-hybrid-micelles-with-lymph-node-targeting-ability-to-improve-the-potency-of-cancer-vaccines
#2
Qin Zeng, Hanmei Li, Hao Jiang, Jiao Yu, Ying Wang, Huan Ke, Tao Gong, Zhirong Zhang, Xun Sun
It has been widely accepted that lymph nodes (LNs) are critical targets of cancer vaccines and particles sized between 10 and 100 nm with a neutral or negative surface charge are preferred for lymphatic transfer after subcutaneous or intradermal injection. However their limited uptake by antigen presenting cells (APCs) and inadequate retention within LNs undoubtedly restrains their strength on activating T cell immunity. Here, we address this issue by tailoring the physicochemical properties of polymeric hybrid micelles (HMs), which are self-assembled from two amphiphilic diblock copolymers, poly-(ethylene glycol) phosphorethanolamine (PEG-PE) and polyethylenimine-stearic acid conjugate (PSA) via hydrophobic and electrostatic interactions...
January 11, 2017: Biomaterials
https://www.readbyqxmd.com/read/28109202/algoriphagus-resistens-sp-nov-isolated-from-marine-sediment
#3
Ji-Ru Han, Jin-Xin Zhao, Zong-Jie Wang, Guan-Jun Chen, Zong-Jun Du
Strain NH1T, a pink-pigmented, facultatively anaerobic, heterotrophic, catalase-positive and oxidase-negative, Gram-stain-negative marine bacterium, was isolated from marine sediment in the coast of Weihai, China. Cells of strain NH1T was rod-shaped, 0.8-2.0 µm in length and 0.5 µm in width. The strain able to grow at 13-37 °C, pH 5.5-8.5, in the presence of 0.0-8.0% (w/v) NaCl. Optimal growth was observed at 28 °C, with 3.0% (w/v) NaCl and pH 6.5-7.0. Nitrate was reduced. The G+C content of the DNA was 41...
January 19, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28108415/how-does-mindfulness-modulate-self-regulation-in-pre-adolescent-children-an-integrative-neurocognitive-review
#4
REVIEW
Rebekah Jane Kaunhoven, Dusana Dorjee
Pre-adolescence is a key developmental period in which complex intrinsic volitional methods of self-regulation are acquired as a result of rapid maturation within the brain networks underlying the self-regulatory processes of attention control and emotion regulation. Fostering adaptive self-regulation skills during this stage of development has strong implications for physical health, emotional and socio-economic outcomes during adulthood. There is a growing interest in mindfulness-based programmes for pre-adolescents with initial findings suggesting self-regulation improvements, however, neurodevelopmental studies on mindfulness with pre-adolescents are scarce...
January 17, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28108381/metabolomic-study-of-the-intervention-effects-of-shuihonghuazi-formula-a-traditional-chinese-medicinal-formulae-on-hepatocellular-carcinoma-hcc-rats-using-performance-hplc-esi-tof-ms
#5
Yongrui Bao, Shuai Wang, Xinxin Yang, Li Tianjiao, Mingyue Xia, Xiansheng Meng
ETHNOPHARMACOLOGICAL RELEVANCE: Metabolomics is the comprehensive assessment of endogenous metabolites of a biological system in a holistic context, and its property consists with the global view of Traditional Chinese Medicine (TCM). Shuihonghuazi Formula (SHHZF) has been used for liver cancer early treatment in clinical for more than thirty years, but its mechanism remains unclear completely. This paper was designed to explore the therapeutic effects of SHHZF on liver cancer and its metabolomic characters...
January 17, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28107887/associations-between-positive-emotional-well-being-and-stress-induced-myocardial-ischemia-well-being-scores-predict-exercise-induced-ischemia
#6
Jacob P Feigal, Stephen H Boyle, Zainab Samad, Eric J Velazquez, Jennifer L Wilson, Richard C Becker, Redford B Williams, Cynthia M Kuhn, Thomas L Ortel, Joseph G Rogers, Christopher M O'Connor, Wei Jiang
OBJECTIVE: Depressive symptoms have been associated with myocardial ischemia induced by mental (MSIMI) and exercise (ESIMI) stress in clinically stable ischemic heart disease (IHD) patients, but the association between positive emotions and inducible ischemia is less well characterized. The objective of this study was to examine the associations between ratings of well-being and stress-induced ischemia. METHODS: Subjects were adult patients with documented IHD underwent mental and exercise stress testing for the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) trial...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107782/ultra-low-parasitic-energy-for-post-combustion-co2-capture-realized-in-a-nickel-isonicotinate-mof-with-excellent-moisture-stability
#7
Shyamapada Nandi, Sean P Collins, Debanjan Chakraborty, Debasis Banerjee, Praveen K Thallapally, Tom K Woo, Ramanathan Vaidhyanathan
MOFs have attracted significant attention as solid sorbents in gas separation processes for low-energy post-combustion CO2 capture. The parasitic energy (PE) has been put forward as a holistic parameter that measures how energy efficient (and therefore cost-effective) the CO2 capture process will be using the material. In this work, we present a nickel isonicotinate based ultra-microporous MOF, 1 [Ni-(4PyC)2⦁DMF], that has the lowest PE for post-combustion CO2 capture reported to date. We calculate a PE of 655 kJ/kg CO2, which is lower than that of the best performing material previously reported, Mg-MOF-74...
January 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28107698/the-natural-flavonoid-apigenin-sensitizes-human-cd44-prostate-cancer-stem-cells-to-cisplatin-therapy
#8
Suat Erdogan, Kader Turkekul, Rıza Serttas, Zeynep Erdogan
Prostate cancer (PCa) is the second most common type of cancer and the fifth leading cause of cancer-related death among men. Development of chemoresistance, tumor relapse and metastasis remain major barriers to effective treatment and all been identified to be associated with cancer stem cells (CSCs). Natural flavonoids such as apigenin have been shown to have the ability to improve the therapeutic efficacy of common chemotherapy agents through CSCs sensitization. Thus, the aim of this study was to evaluate the combination of apigenin with cisplatin on CD44(+) PCa stem cell growth and migration...
January 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28107468/micro-x-ray-computed-tomography-mass-loss-assessment-of-different-uhmwpe-a-hip-joint-simulator-study-on-standard-vs-cross-linked-polyethylene
#9
Saverio Affatato, Filippo Zanini, Simone Carmignato
More than 60.000 hip arthroplasty are performed every year in Italy. Although Ultra-High-Molecular-Weight-Polyethylene remains the most used material as acetabular cup, wear of this material induces over time in vivo a foreign-body response and consequently osteolysis, pain, and the need of implant revision. Furthermore, oxidative wear of the polyethylene provoke several and severe failures. To solve these problems, highly cross-linked polyethylene and Vitamin-E-stabilized polyethylene were introduced in the last years...
2017: PloS One
https://www.readbyqxmd.com/read/28106456/interplay-between-adsorption-and-hydrodynamics-in-nanochannels-towards-tunable-membranes
#10
Sela Samin, René van Roij
We study how the adsorption of a near-critical binary mixture in a nanopore is modified by flow inside the pore. We identify three types of steady states upon variation of the pore Péclet number (Pe_{p}), which can be reversibly accessed by the application of an external pressure. Interestingly, for small Pe_{p} the pore acts as a weakly selective membrane which separates the mixture. For intermediate Pe_{p}, the flow effectively shifts the adsorption in the pore, thereby opening possibilities for enhanced and tunable solute transport through the pore...
January 6, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28106343/net-clinical-benefit-of-hospitalization-versus-outpatient-management-of-patients-with-acute-pulmonary-embolism
#11
P-M Roy, D J Corsi, M Carrier, A Theogene, C de Wit, C Dennie, G Le Gal, A Delluc, T Moumneh, M Rodger, P Wells, E Gandara
BACKGROUND: The decision to hospitalize or not patients with acute pulmonary embolism (PE) is controversial. Despite the advantages of close monitoring, hospitalization by itself may lead to in-hospital complications and potentially worsen the prognosis of PE patients. OBJECTIVES: To determine the net clinical benefit of hospitalization versus outpatient management of normotensive patients with acute pulmonary embolism (PE). METHODS: Retrospective cohort propensity score analysis (radius marching with replacement)...
January 20, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28106338/the-original-and-simplified-wells-rules-and-age-adjusted-d-dimer-testing-to-rule-out-pulmonary-embolism-an-individual-patient-data-meta-analysis
#12
Nick van Es, Noémie Kraaijpoel, Frederikus A Klok, Menno V Huisman, Paul L Den Exter, Inge C M Mos, Javier Galipienzo, Harry R Büller, Patrick M Bossuyt
BACKGROUND: The Wells score and D-dimer testing can safely rule out pulmonary embolism (PE). A simplification of the Wells score has been proposed to improve clinical applicability, but evidence on its performance is scarce. OBJECTIVES: To compare the performance of the original and simplified Wells scores alone and in combination with age-adjusted D-dimer testing. METHODS: Individual patient data from 7,268 patients with suspected PE enrolled in 6 management studies were used to evaluate the discriminatory performance of the original and simplified Wells scores...
January 20, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28105904/increasing-use-of-ctpa-for-the-investigation-of-suspected-pulmonary-embolism
#13
Sidharth Sharma, Christopher D Lucas
OBJECTIVES: Pulmonary embolism (PE) is a frequently suspected life-threatening condition that often presents with non-specific signs and symptoms. There is concern that increased availability of computerized tomography pulmonary angiogram (CTPA) is resulting in overuse in the diagnostic workup of patients presenting with cardio-respiratory symptoms. We therefore aimed to determine whether use of CTPA was increasing over time within our institution, with a consequent decrease in the diagnostic yield of PE...
January 20, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28105830/improving-performance-metrics-of-ultraviolet-photodissociation-mass-spectrometry-by-selective-precursor-ejection
#14
Dustin D Holden, Jennifer S Brodbelt
Confident protein identifications derived from high-throughput bottom-up and top-down proteomics workflows depend on acquisition of thousands of tandem mass spectrometry (MS/MS) spectra with adequate signal-to-noise and accurate mass assignments of the fragment ions. Ultraviolet photodissociation (UVPD) using 193 nm photons has proven to be well-suited for activation and fragmentation of peptides and proteins in ion trap mass spectrometers, but the spectral signal-to-noise ratio (S/N) is typically lower than that obtained from collisional activation methods...
January 3, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28105336/dysregulated-circulating-mirnas-in-preeclampsia
#15
Carine Munaut, Linda Tebache, Silvia Blacher, Agnès Noël, Michelle Nisolle, Frédéric Chantraine
Preeclampsia (PE) is a pregnancy-related disease with potentially severe consequences with respect to foeto-maternal morbidity and mortality. However, the molecular pathogenesis of PE remains largely unknown. Recent reports have shown that microRNAs (miRNAs or miRs) may play important roles in the development of PE. Analysing the miRNAs in sera from preeclamptic women may improve our understanding of the pathophysiological mechanisms of the disease. The aim of this retrospective study was to identify whether circulating miRNAs were differentially expressed in PE patients compared with controls...
December 2016: Biomedical Reports
https://www.readbyqxmd.com/read/28105119/clinical-observation-on-the-treatment-of-acute-liver-failure-by-combined-non-biological-artificial-liver
#16
Maoqin Li, Jingxi Sun, Jiaqiong Li, Zaixiang Shi, Jiyuan Xu, Bo Lu, Shuli Cheng, Yanjun Xu, Xiaomeng Wang, Xianjiang Zhang
The clinical efficacy and safety of different combinations of non-bio artificial liver in the treatment of acute liver failure was examined. A total of 61 cases were selected under blood purification treatment from the patients with severe acute liver failure admitted to the severe disease department of the hospital from December, 2010 to December, 2015. Three types of artificial liver combinations were observed, i.e., plasma exchange plus hemoperfusion plus continuous venovenous hemodiafiltration (PE+HP+CVVHDF), PE+CVVHDF and HP+CVVHDF...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28103790/microrna-146a-rs2910164-is-associated-with-severe-preeclampsia-in-black-south-african-women-on-haart
#17
Niren Ray Maharaj, Prithiksha Ramkaran, Siddharthiya Pillay, Anil Amichund Chuturgoon
BACKGROUND: South African (SA) Black women have a high prevalence of preeclampsia and HIV, both conditions associated with increased inflammation. miR-146a is an inflammatory-associated miR and a common single nucleotide polymorphism (rs2910164) has been associated with several disease conditions. To date, this SNP has not been investigated in SA Black women. We therefore aimed to investigate the miR-146a G > C SNP in SA Blacks with preeclampsia, and further examine possible association among preeclamptic (PE) women with HIV infection on HAART...
January 19, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28103401/maintenance-and-reach-of-exposure-psychotherapy-for-posttraumatic-stress-disorder-18-months-after-training
#18
Craig S Rosen, Afsoon Eftekhari, Jill J Crowley, Brandy N Smith, Eric Kuhn, Lindsay Trent, Nicole Martin, Thuy Tran, Josef I Ruzek
This study examined aspects of clinicians' work environment that facilitated sustained use of prolonged exposure (PE) therapy. Surveys were completed by 566 U.S. Department of Veterans Affairs clinicians 6 and 18 months after intensive training in PE. The number of patients treated with PE at 18 months (reach) was modeled as a function of clinician demographics, clinician beliefs about PE, and work context factors. There were 342 clinicians (60.4%) who used PE at 6 and 18 months after training, 58 (10.2%) who used PE at 18 but not 6 months, 95 (16...
January 19, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28102332/dynamic-modeling-of-uteroplacental-blood-flow-in-iugr-indicates-vortices-and-elevated-pressure-in-the-intervillous-space-a-pilot-study
#19
Christian J Roth, Eva Haeussner, Tanja Ruebelmann, Franz V Koch, Christoph Schmitz, Hans-Georg Frank, Wolfgang A Wall
Ischemic placental disease is a concept that links intrauterine growth retardation (IUGR) and preeclampsia (PE) back to insufficient remodeling of uterine spiral arteries. The rheological consequences of insufficient remodeling of uterine spiral arteries were hypothesized to mediate the considerably later manifestation of obstetric disease. However, the micro-rheology in the intervillous space (IVS) cannot be examined clinically and rheological animal models of the human IVS do not exist. Thus, an in silico approach was implemented to provide in vivo inaccessible data...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28101835/relationships-between-perceived-family-gambling-and-peer-gambling-and-adolescent-problem-gambling-and-binge-drinking
#20
Zu Wei Zhai, Sarah W Yip, Marvin A Steinberg, Jeremy Wampler, Rani A Hoff, Suchitra Krishnan-Sarin, Marc N Potenza
The study systematically examined the relative relationships between perceived family and peer gambling and adolescent at-risk/problem gambling and binge-drinking. It also determined the likelihood of at-risk/problem gambling and binge-drinking as a function of the number of different social groups with perceived gambling. A multi-site high-school survey assessed gambling, alcohol use, presence of perceived excessive peer gambling (peer excess-PE), and family gambling prompting concern (family concern-FC) in 2750 high-school students...
January 18, 2017: Journal of Gambling Studies
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