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https://www.readbyqxmd.com/read/29774399/endothelial-dysfunction-following-coronary-artery-bypass-grafting-influence-of-patient-and-procedural-factors
#1
J Hadem, R Rossnick, B Hesse, M Herr, M Hansen, A Bergmann, G Kensah, C Maess, H Baraki, P Kümpers, A Lukasz, I Kutschka
BACKGROUND: Angiopoietin-2 (Angpt2) mediates endothelial dysfunction (ED) following coronary artery bypass grafting (CABG). Its triggers are, however, poorly understood. METHODS: We examined the time course of ED beyond the early phase of postoperative recovery in 75 patients following CABG with a special focus on different cardiopulmonary bypass (CPB) modes as potential triggers of Angpt2 release. RESULTS: Nine patients (12.0%) underwent off-pump coronary artery bypass (OPCAB), 31 patients (41...
May 17, 2018: Herz
https://www.readbyqxmd.com/read/29771744/sleep-quality-during-and-after-cardiothoracic-intensive-care-and-psychological-health-during-recovery
#2
Nittaya Caruana, Sharon McKinley, Rosalind Elliott, Leila Gholizadeh
BACKGROUND: Intensive care patients experience poor sleep quality. Psychological distress and diminished health-related quality of life (HRQOL) are also common among former intensive care unit (ICU) patients. Coronary artery bypass graft (CABG) surgery is a frequent reason adults require treatment in ICU. The effect of on- versus off-pump surgery on sleep and recovery has not been reported. OBJECTIVE: The aim of this study was to assess sleep quality of CABG patients during and after ICU, psychological well-being, HRQOL during recovery, and whether on- versus off-pump surgery affects sleep and recovery...
May 16, 2018: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29759732/thoracoscopic-off-pump-closure-of-a-large-left-circumflex-coronary-artery-fistula-a-novel-minimally-invasive-approach
#3
Ines Van Loo, Jeroen Sonck, Kaoru Tanaka, Mark La Meir
No abstract text is available yet for this article.
April 17, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29754654/dual-antiplatelet-therapy-for-perioperative-myocardial-infarction-following-cabg-surgery
#4
Alice Wang, Angie Wu, Daniel Wojdyla, Renato D Lopes, L Kristin Newby, Mark F Newman, Peter K Smith, John H Alexander
OBJECTIVES: Perioperative myocardial infarction (MI) after coronary artery bypass graft surgery (CABG) has been associated with adverse outcome. Whether perioperative MI should be treated with dual antiplatelet therapy (DAPT) is unknown. We compared the effect of DAPT versus aspirin alone on short-term outcomes among patients with perioperative MI following CABG. METHODS: We used data from 3 clinical trials that enrolled patients undergoing isolated CABG: PREVENT IV (2002-2003), MEND-CABG II (2004-2005), and RED-CABG (2009-2010) (n = 9117)...
May 2018: American Heart Journal
https://www.readbyqxmd.com/read/29753665/off-pump-versus-on-pump-coronary-artery-bypass-grafting-a-systematic-review-and-analysis-of-clinical-outcomes
#5
REVIEW
Shahzad Shaefi, Aaron Mittel, Dan Loberman, Harish Ramakrishna
Surgical coronary artery bypass grafting (CABG) is the standard of care for revascularization of left main or three-vessel coronary artery disease. The off-pump coronary artery bypass graft (OPCAB) procedure avoids the use of cardiopulmonary bypass. Theoretically, OPCAB may improve long-term outcomes by reducing the rates of perioperative myocardial injury, stroke, neurocognitive impairment, and cardiac-related mortality. Several high-quality clinical trials have been conducted since OPCAB became popular in the 1990s and have demonstrated no benefit of OPCAB over traditional CABG with respect to these outcomes despite favorable short-term reductions in transfusion requirements and other postoperative complications...
April 4, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29753505/off-pump-technique-reduces-surgical-mortality-after-elective-coronary-artery-bypass-grafting-in-patients-with-preoperative-renal-failure
#6
Chikara Ueki, Hiroaki Miyata, Noboru Motomura, Ryuzo Sakata, Genichi Sakaguchi, Takehide Akimoto, Shinichi Takamoto
OBJECTIVES: Most randomized controlled trials of off-pump versus on-pump coronary artery bypass grafting (CABG) have included limited numbers of patients with preoperative renal failure. This study was performed to evaluate the association between the clinical benefit of the off-pump technique and chronic kidney disease stage. METHODS: We analyzed 38,051 patients with chronic kidney disease who underwent primary nonemergent isolated CABG from 2013 to 2015 as reported in the Japan Cardiovascular Surgery Database-Adult section...
April 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29730107/on-pump-or-off-pump-right-debate-but-wrong-question
#7
EDITORIAL
Antonio M Calafiore, Michele Di Mauro
No abstract text is available yet for this article.
March 31, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29729267/good-five-year-durability-of-transapical-beating-heart-off-pump-mitral-valve-repair-with-neochordae
#8
Philipp Kiefer, Sabine Meier, Thilo Noack, Michael Andrew Borger, Joerg Ender, Alexandro Hoyer, Friedrich Wilhelm Mohr, Joerg Seeburger
BACKGROUND: Transapical, beating heart, off-pump implantation of neochordae for repair of mitral valve (MV) prolapse is of increasing interest. The aim of this study was to evaluate long term results for MV repair using the NeoChord system. METHODS: Six patients underwent treatment for severe primary mitral regurgitation (MR) using the NeoChord DS1000 system as part of the initial device safety and feasibility Transapical Artificial Chordae Tendinae (TACT) trial at our institution...
May 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29729266/good-five-year-durability-of-transapical-beating-heart-off-pump-mitral-valve-repair-with-neochordae-commentary
#9
Gino Gerosa
No abstract text is available yet for this article.
May 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29727155/reflectivity-effects-on-pump-probe-spectra-of-lead-halide-perovskites-comparing-thin-films-vs-nanocrystals
#10
Tufan Ghosh, Sigalit Aharon, Adva Shpatz, Lioz Etgar, Sanford Ruhman
Due to their sizable refractive index, reflectivity of visible light off the lead halide perovskite - air interface exceeds 15%. This has prompted a number of investigations into the prominence of photo-reflective contributions to pump-probe data in these materials, with conflicting results. Here we report experiments aimed at assessing this by comparing transient transmission from lead halide perovskite films and weakly quantum confined nanocrystals of cesium lead iodide (CsPbI3) perovskite. By analyzing how complex refractive index changes impact the two experiments, results demonstrate that changes in absorption and not reflection dominate transient transmission measurements in thin films of these materials...
May 4, 2018: ACS Nano
https://www.readbyqxmd.com/read/29726986/propensity-matched-analysis-of-a-side-clamp-versus-an-anastomosis-assist-device-in-cases-of-isolated-coronary-artery-bypass-grafting
#11
Aya Saito, Hiraku Kumamaru, Minoru Ono, Hiroaki Miyata, Noboru Motomura
OBJECTIVES: The use of an anastomosis assist device during coronary artery bypass grafting (CABG) is considered less invasive for the ascending aorta than the use of a side-biting clamp (Side-clamp) and to possibly be associated with a lower incidence of postoperative stroke. However, this benefit has not yet been clearly demonstrated. This study was to evaluate whether the use of an anastomosis assist device will minimize the postoperative stroke and other complications in patients undergoing off-pump CABG in comparison with the use of the Side-clamp...
May 2, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29721424/nir-triggered-crystal-phase-transformation-of-niti-layered-double-hydroxides-films-for-localized-chemothermal-tumor-therapy
#12
Donghui Wang, Naijian Ge, Tingting Yang, Feng Peng, Yuqin Qiao, Qianwen Li, Xuanyong Liu
Construction of localized drug-eluting systems with synergistic chemothermal tumor-killing abilities is promising for biomedical implants directly contacting with tumor tissues. In this study, an intelligent and biocompatible drug-loading platform, based on a gold nanorods-modified butyrate-inserted NiTi-layered double hydroxides film (Au@LDH/B), is prepared on the surface of nitinol alloy. The prepared films function as drug-loading "sponges," which pump butyrate out under near-infrared (NIR) irradiation and resorb drugs in water when the NIR laser is shut off...
April 2018: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/29707327/the-curative-effect-of-synthetic-treatment-for-refractory-acute-myocardial-infarction
#13
Jing Xie, Ding-Xiong Xie, Yi-Rong Gan, Jiong Li, Yan-Zhen Wang, Zong-Ke Kou, Rui Mao, Tian-Xiang Liang, Yun-Long Zhang
Background: This study aims to investigate the curative effect of synthetic treatment for refractory acute myocardial infarction (AMI). Methods: A total of 76 patients with coronary AMI accompanied by shock, who were treated with combined therapy from August 1999 to April 2017, were included into this study. Sixty patients received emergency percutaneous coronary intervention (PCI). Among these patients, 39 patients received intra-aortic balloon counterpulsation (IABP), eight patients had failed PCI underwent emergency off-pump coronary artery bypass (E-OPCAB), and eight patients were treated by hybrid cardiac surgery...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29701336/cabg-to-cbp-or-not-to-cbp-a-propensity-score-matched-survival
#14
Pedro Magro, Sérgio Boshoff, José Calquinha, Miguel Sousa Uva, José Neves
INTRODUCTION: Over the past 3 decades two main strategies have been employed for surgical coronary revascularization (CABG): on- pump CABG with cardioplegia (ONCAB) and off-pump CABG (OPCAB). The objective of this study is to evaluate the short-term and long-term survival of the two strategies. METHODS: This study consists of 8-year cohort, retrospective single-center analysis with an intention-to-treat design. 2954 patients underwent CABG (OPCAB n=2123; ONCAB= 831) for CAD...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29695870/an-optical-frequency-synthesizer-using-integrated-photonics
#15
Daryl T Spencer, Tara Drake, Travis C Briles, Jordan Stone, Laura C Sinclair, Connor Fredrick, Qing Li, Daron Westly, B Robert Ilic, Aaron Bluestone, Nicolas Volet, Tin Komljenovic, Lin Chang, Seung Hoon Lee, Dong Yoon Oh, Myoung-Gyun Suh, Ki Youl Yang, Martin H P Pfeiffer, Tobias J Kippenberg, Erik Norberg, Luke Theogarajan, Kerry Vahala, Nathan R Newbury, Kartik Srinivasan, John E Bowers, Scott A Diddams, Scott B Papp
Optical-frequency synthesizers, which generate frequency-stable light from a single microwave-frequency reference, are revolutionizing ultrafast science and metrology, but their size, power requirement and cost need to be reduced if they are to be more widely used. Integrated-photonics microchips can be used in high-coherence applications, such as data transmission 1 , highly optimized physical sensors 2 and harnessing quantum states 3 , to lower cost and increase efficiency and portability. Here we describe a method for synthesizing the absolute frequency of a lightwave signal, using integrated photonics to create a phase-coherent microwave-to-optical link...
April 25, 2018: Nature
https://www.readbyqxmd.com/read/29693223/off-pump-hemostasis-for-left-ventricular-rupture-after-myocardial-infarction-with-hydrofit-%C3%A2-and-surgicel-%C3%A2
#16
Hikaru Ishii, Hidehito Endo, Hiroshi Tsuchiya, Yusuke Inaba, Katsunari Terakawa, Hiroshi Kubota
Left ventricular free wall rupture (LVFWR) is a catastrophic complication of myocardial infarction. In these cases, cardiopulmonary bypass (CPB) should be performed for left ventricular repair, but can impact hemodynamic stability. An 87-year-old man presented with acute shock. He was diagnosed with LVFWR after myocardial infarction. We describe a simple, effective, and reproducible technique to achieve hemostasis at the LVFWR site during emergency operation using Hydrofit® and Surgicel® surgical hemostatic agents...
April 24, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29682761/in-vitro-hemodynamic-evaluation-of-ecg-synchronized-pulsatile-flow-using-i-cor-pump-as-short-term-cardiac-assist-device-for-neonatal-and-pediatric-population
#17
Madison Force, Morgan Moroi, Shigang Wang, Allen R Kunselman, Akif Ündar
The objective of this study was to assess the hemodynamic properties of the i-cor ECG-synchronized cardiac assist system for off-label use as a short-term cardiac assist device for neonatal and pediatric patients and compare nonpulsatile to pulsatile flow with different amplitudes. The circuit consisted of the i-cor diagonal pump with 3 feet of ¼ inch arterial and venous tubing and a soft-shell reservoir, primed with lactated Ringer's solution and human packed red blood cells (hematocrit 42%). Trials were conducted with three different sets of cannulas (8-Fr arterial 10-Fr venous, 10-Fr arterial 12 Fr-venous, and 12-Fr arterial 14-Fr venous) with increasing flow rates at varying pseudo-patient pressures (40, 60, 80, and 100 mm Hg) and under nonpulsatile mode and pulsatile mode with pulsatile amplitudes 2000, 2500, and 3000 rpm at 36°C...
April 22, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29681623/lack-of-improvement-of-impaired-chemical-clearance-characterizes-ppi-refractory-reflux-related-heartburn
#18
Marzio Frazzoni, Leonardo Frazzoni, Salvatore Tolone, Nicola De Bortoli, Vincenzo Savarino, Edoardo Savarino
OBJECTIVE: Heartburn is the most specific symptom of reflux disease and is highly responsive to proton pump inhibitor (PPI) therapy. Some patients do not respond to PPIs, but mechanisms of refractoriness have not yet been fully elucidated. Impedance-pH monitoring, allowing comprehensive on-therapy assessment of reflux, represents a valuable test to investigate PPI refractoriness. METHODS: Prospective multicenter study comparing endoscopy-negative patients with PPI-refractory and PPI-responsive heartburn...
April 23, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29681566/off-pump-coronary-artery-bypass-grafting-with-mini-sternotomy-in-the-treatment-of-triple-vessel-coronary-artery-disease
#19
Pixiong Su, Song Gu, Yan Liu, Xitao Zhang, Jun Yan, Xiangguang An, Jie Gao, Yue Xin, Jian Zhou
We have developed off-pump coronary artery bypass approach with lower distal mini-sternotomy (TM-OPCAB) for multivessel coronary revascularization. The aim of this retrospective study is to provide evidence for the feasibility and safety of this technique in the treatment of triple-vessel diseases.Two hundred eighty-eight patients with triple-vessel coronary artery disease who underwent TM-OPCAB or standard off-pump coronary artery bypass surgery (S-OPCAB) were included in this study after propensity-score matching...
April 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29666009/in-vitro-validation-of-a-self-driving-aortic-turbine-venous-assist-device-for-fontan-patients
#20
Kerem Pekkan, Ibrahim Basar Aka, Ece Tutsak, Erhan Ermek, Haldun Balim, Ismail Lazoglu, Riza Turkoz
BACKGROUND: Palliative repair of single ventricle defects involve a series of open-heart surgeries where a single-ventricle (Fontan) circulation is established. As the patient ages, this paradoxical circulation gradually fails, because of its high venous pressure levels. Reversal of the Fontan paradox requires an extra subpulmonic energy that can be provided through mechanical assist devices. The objective of this study was to evaluate the hemodynamic performance of a totally implantable integrated aortic-turbine venous-assist (iATVA) system, which does not need an external drive power and maintains low venous pressure chronically, for the Fontan circulation...
March 11, 2018: Journal of Thoracic and Cardiovascular Surgery
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