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SPECT MPI

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https://www.readbyqxmd.com/read/28439760/prognostic-study-of-cardiac-events-in-japanese-patients-with-chronic-kidney-disease-using-ecg-gated-myocardial-perfusion-imaging-final-3-year-report-of-the-j-access-3-study
#1
Satoko Nakamura, Yuhei Kawano, Kenichi Nakajima, Hiroki Hase, Nobuhiko Joki, Tsuguru Hatta, Shigeyuki Nishimura, Masao Moroi, Susumu Nakagawa, Tokuo Kasai, Hideo Kusuoka, Yasuchika Takeishi, Mitsuru Momose, Kazuya Takehana, Mamoru Nanasato, Syunichi Yoda, Hidetaka Nishina, Naoya Matsumoto, Tsunehiko Nishimura
BACKGROUND: Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media. METHODS AND RESULTS: The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients without a definitive coronary artery disease...
April 24, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28406042/attributes-of-nuclear-imaging-centers-impacting-physician-referrals-for-single-photon-emission-computed-tomography-myocardial-perfusion-imaging-tests
#2
Junlong Li, Christy R Houle, James R Spalding, Hongbo Yang, Cheryl Q Xiang, Therese M Kitt, Rita M Kristy, Eric Q Wu
AIM: To evaluate nuclear imaging center attributes that cardiologists and primary care physicians (PCPs) consider when referring patients for single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) tests, and how these attributes impact physician referral decisions in the United States. METHODS: A targeted literature review and seven one-to-one interviews with physicians and imaging center directors were conducted to identify attributes that could impact physicians' referral decisions...
April 13, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28405882/iq-spect-for-thallium-201-myocardial-perfusion-imaging-effect-of-normal-databases-on-quantification
#3
Takahiro Konishi, Kenichi Nakajima, Koichi Okuda, Hiroto Yoneyama, Shinro Matsuo, Takayuki Shibutani, Masahisa Onoguchi, Seigo Kinuya
OBJECTIVE: Although IQ-single-photon emission computed tomography (SPECT) provides rapid acquisition and attenuation-corrected images, the unique technology may create characteristic distribution different from the conventional imaging. This study aimed to compare the diagnostic performance of IQ-SPECT using Japanese normal databases (NDBs) with that of the conventional SPECT for thallium-201 ((201)Tl) myocardial perfusion imaging (MPI). METHODS: A total of 36 patients underwent 1-day (201)Tl adenosine stress-rest MPI...
April 12, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28400923/significance-of-inferior-wall-ischemia-in-non-dominant-right-coronary-artery-anatomy
#4
Ali Osama Malik, Oliver Abela, Subodh Devabhaktuni, Arhama Aftab Malik, Gayle Allenback, Chowdhury H Ahsan, Sanjay Malhotra, Jimmy Diep
AIM: To investigate the relationship of inferior wall ischemia on myocardial perfusion imaging in patients with non-dominant right coronary artery anatomy. METHODS: This was a retrospective observational analysis of consecutive patients who presented to the emergency department with primary complaint of chest pain. Only patients who underwent single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) were included. Patients who showed a reversible defect on SPECT MPI and had coronary angiography during the same hospitalization was analyzed...
March 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28377546/high-prevalence-of-coronary-artery-calcification-in-saudi-patients-with-normal-myocardial-perfusion
#5
Ahmed L Fathala, Salwa Q Bukhari, Mohamed Shoukri, Hani El Sergani, Bandar Al-Ghamdi, Abdulaziz Al-Sugair
BACKGROUND: Normal single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) has a high negative predictive value for ischemic heart disease. Thus, the presence of subclinical coronary atherosclerosis detected by coronary artery calcification (CAC) score in patients who have under-gone SPECT MPI is unknown. OBJECTIVES: Determine the prevalence of coronary artery calcification (CAC) in patients with normal SPECT MPI and examine the association of CAC with conventional coronary artery disease (CAD) risk factors...
March 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28353213/development-and-validation-of-an-automatic-method-to-detect-the-latest-contracting-viable-left-ventricular-segments-to-assist-guide-crt-therapy-from-gated-spect-myocardial-perfusion-imaging
#6
Weihua Zhou, Ningchao Tao, Xiaofeng Hou, Yao Wang, Russell D Folks, David C Cooke, Valeria M Moncayo, Ernest V Garcia, Jiangang Zou
OBJECTIVES: The purpose of this study is to use ECG-gated SPECT MPI to detect the latest contracting viable left ventricular (LV) segments to help guide the LV probe placement used in CRT therapy and to validate segment selection against the visual integration method by experts. METHODS: For each patient, the resting ECG-gated SPECT MPI short-axis images were sampled in 3D to generate a polar map of the perfusion distribution used to determine LV myocardial viability, and to measure LV synchronicity using our phase analysis tool...
March 28, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28330657/diagnostic-accuracy-of-myocardial-perfusion-imaging-with-czt-technology-systemic-review-and-meta-analysis-of-comparison-with%C3%A2-invasive-coronary-angiography
#7
Francesco Nudi, Ami E Iskandrian, Orazio Schillaci, Mariangela Peruzzi, Giacomo Frati, Giuseppe Biondi-Zoccai
OBJECTIVES: This study sought to summarize the evidence on stress myocardial perfusion imaging (MPI) using cadmium-zinc-telluride (CZT) technology for the diagnosis of obstructive coronary artery disease (CAD). The CZT cameras are newly introduced, and comparative data with the conventional Anger technology (Anger-MPI) are lacking. BACKGROUND: The diagnostic accuracy of Anger-MPI for detection of angiographically significant CAD is well established; however, less evidence is available on the diagnostic accuracy of CZT-MPI...
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28290100/triage-of-patients-for-attenuation-corrected-stress-first-tc-99m-spect-mpi-using-a-simplified-clinical-pre-test-scoring-model
#8
Shreyas Gowdar, Waseem Chaudhry, Alan W Ahlberg, Milena J Henzlova, W Lane Duvall
BACKGROUND: Stress-only Tc-99m SPECT MPI saves time and reduces radiation exposure while a normal study has a benign prognosis. However, no guidelines exist as to which patients should undergo stress-first MPI. The purpose of this study was to validate a previously published pre-test prediction scoring model and refine the stress-first triage process further if possible. METHODS: We retrospectively reviewed all patients who underwent an attenuation-corrected Tc-99m SPECT MPI over a 39-month period...
March 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28290099/fully-automated-analysis-of-attenuation-corrected-spect-for-the-long-term-prediction-of-acute-myocardial-infarction
#9
Manish Motwani, William D Leslie, Andrew L Goertzen, Yuka Otaki, Guido Germano, Daniel S Berman, Piotr J Slomka
BACKGROUND: Most prior studies assessing the prognostic value of SPECT myocardial perfusion imaging (MPI) have used semi-quantitative visual analysis. We assessed the feasibility of large-scale fully automated quantitative analysis of SPECT MPI to predict acute myocardial infarction (AMI). Additionally, we examined the impact of attenuation correction (AC) in automated strategies. METHODS AND RESULTS: 5960 patients underwent rest/stress SPECT MPI with AC. Left ventricular (LV) segmentation, contour QC check, and quantitation of stress and ischemic total perfusion deficit (sTPD, iTPD) were performed...
March 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28281088/prognostic-impact-of-myocardial-perfusion-single-photon-emission-computed-tomography-in-patients-with-major-extracardiac-findings-by-computed-tomography-for-attenuation-correction
#10
Charline Zadro, Noé Roussel, Emmanuelle Cassol, Pierre Pascal, Antoine Petermann, Olivier Meyrignac, Marion Jaffro, Pauline Fournier, Maxime Cournot, Michel Galinier, Didier Carrié, Hervé Rousseau, Isabelle Berry, Olivier Lairez
BACKGROUND: Attenuation correction computed tomography (CT) contributes to an improvement in the diagnostic accuracy of myocardial perfusion imaging (MPI) by single photon emission tomography (SPECT). The aim of this study was to explore the prognosis of patients with major findings by CT according to the results of MPI. METHODS AND RESULTS: 1506 patients who underwent MPI by SPECT were retrospectively included. Attenuation correction CT images were systematically analyzed for major and minor abnormalities...
March 9, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28276752/new-solid-state-cadmium-zinc-telluride-technology-for-cardiac-single-photon-emission-computed-tomographic-myocardial-perfusion-imaging
#11
REVIEW
Ali B Alenazy, R Glenn Wells, Terrence D Ruddy
Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is well established as diagnostic test for patients with suspected or known coronary artery disease. New camera systems have been developed with cadmium-zinc-telluride (CZT) detectors, novel collimator designs and reconstruction software. Areas covered: We review the current state of cardiac SPECT, advances in conventional camera technology and the development and clinical validation of solid-state CZT cameras. Expert commentary: The development of CZT systems is timely and addresses current issues for clinical SPECT imaging...
March 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28224449/the-exerrt-trial-exercise-to-regadenoson-in-recovery-trial-a-phase-3b-open-label-parallel-group-randomized-multicenter-study-to-assess-regadenoson-administration-following-an-inadequate-exercise-stress-test-as-compared-to-regadenoson-without-exercise-for-myocardial
#12
Gregory S Thomas, S James Cullom, Therese M Kitt, Kathleen M Feaheny, Karthikeyan Ananthasubramaniam, Robert J Gropler, Diwakar Jain, Randall C Thompson
BACKGROUND: This study assessed the non-inferiority and safety of regadenoson administration during recovery from inadequate exercise compared with administration without exercise. METHODS: Patients unable to achieve adequate exercise stress were randomized to regadenoson 0.4 mg either during recovery (Ex-Reg) or 1 hour after inadequate exercise (Regadenoson) (MPI1). All patients also underwent non-exercise regadenoson MPI 1-14 days later (MPI2). The number of segments with reversible perfusion defects (RPDs) detected using single photon emission computerized tomography imaging was categorized...
February 21, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28194728/diagnostic-performance-of-the-quantification-of-myocardium-at-risk-from-mpi-spect-cta-2g-fusion-for-detecting-obstructive-coronary-disease-a-multicenter-trial
#13
Marina Piccinelli, Cesar Santana, Gopi Kiran R Sirineni, Russell D Folks, C David Cooke, Chesnal D Arepalli, Santiago Aguade-Bruix, Zohar Keidar, Alex Frenkel, Ora Israel, Jaume Candell-Riera, Ernest V Garcia
BACKGROUND: The effective non-invasive identification of coronary artery disease (CAD) and its proper referral for invasive treatment are still unresolved issues. We evaluated our quantification of myocardium at risk (MAR) from our second generation 3D MPI/CTA fusion framework for the detection and localization of obstructive coronary disease. METHODS: Studies from 48 patients who had rest/stress MPI, CTA, and ICA were analyzed from 3 different institutions. From the CTA, a 3D biventricular surface of the myocardium with superimposed coronaries was extracted and fused to the perfusion distribution...
February 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28181156/the-significance-of-post-stress-decrease-in-left-ventricular-ejection-fraction-in-patients-undergoing-regadenoson-stress-gated-spect-myocardial-perfusion-imaging
#14
Javier Gomez, Yasmeen Golzar, Ibtihaj Fughhi, Adebayo Olusanya, Rami Doukky
BACKGROUND: The significance of post-stress decrease in left ventricular ejection fraction (LVEF) with regadenoson stress gated SPECT (GSPECT) myocardial perfusion imaging (MPI) has not been studied. METHODS AND RESULTS: Consecutive patients who underwent rest/regadenoson stress GSPECT-MPI followed by coronary angiography within 6 months were analyzed. Change in LVEF by GSPECT-MPI was calculated as stress LVEF minus rest LVEF; a significant decrease was tested at 5% and 10% thresholds...
February 8, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28160264/impact-of-data-driven-cardiac-respiratory-motion-correction-on-the-extent-and-severity-of-myocardial-perfusion-defects-with-free-breathing-czt-spect
#15
Doumit Daou, Rémy Sabbah, Carlos Coaguila, Hatem Boulahdour
BACKGROUND: We previously reported the clinical feasibility and positive impact on image characteristics of a data-driven cardiac respiratory motion (RM) correction method (REGAT) applicable to CZT SPECT myocardial perfusion imaging (MPI). Here, we evaluate its impact on the extent and severity of myocardial perfusion defects (MPD). METHODS: We included 25 patients having a 1-day (99m)Tc-Tetrofosmin stress/rest MPI acquired with multi-pinhole CZT SPECT. Acquisitions were processed with REGAT to generate mean RM gated SPECT...
February 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28155191/left-ventricular-functional-parameters-by-gated-spect-myocardial-perfusion-imaging-in-a-latin-american-country
#16
Miguel Kapitan, Alvaro Beltran, Mario Beretta, Fernando Mut
BACKGROUND: There is paucity of data on left ventricular (LV) functional parameters using gated SPECT myocardial perfusion imaging (MPI) from the Latin American region. This study provides detailed information in low-risk patients both at rest and during exercise. METHODS AND RESULTS: We studied 90 patients (50 men) with a very low likelihood of coronary artery disease. Gated-SPECT MPI was performed with Tc-99m MIBI using a 2-day protocol, with 16 frames/R-R cycle...
February 2, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28144811/influence-of-acquisition-orbit-on-phase-analysis-of-gated-single-photon-emission-computed-tomography-myocardial-perfusion-imaging-for-assessment-of-left-ventricular-mechanical-dyssynchrony
#17
Tomofumi Misaka, Makoto Hosono, Takashi Kudo, Takamichi Ito, Tsutomu Syomura, Masanobu Uemura, Kaoru Okajima
OBJECTIVE: The association between left ventricular (LV) dyssynchrony parameters, given by phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI), and acquisition orbits is unclear. The aim of this study was to assess the dependence of LV dyssynchrony parameters on acquisition orbits. METHODS: Ninety-nine patients who underwent (201)Tl-gated SPECT MPI were categorized into minor hypoperfusion or major hypoperfusion groups...
April 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28138354/normal-databases-for-the-relative-quantification-of-myocardial-perfusion
#18
Mathieu Rubeaux, Yuan Xu, Guido Germano, Daniel S Berman, Piotr J Slomka
PURPOSE OF REVIEW: Myocardial perfusion imaging (MPI) with SPECT is performed clinically worldwide to detect and monitor coronary artery disease (CAD). MPI allows an objective quantification of myocardial perfusion at stress and rest. This established technique relies on normal databases to compare patient scans against reference normal limits. In this review, we aim to introduce the process of MPI quantification with normal databases and describe the associated perfusion quantitative measures that are used...
August 2016: Current Cardiovascular Imaging Reports
https://www.readbyqxmd.com/read/28077904/regadenoson-in-myocardial-perfusion-study-first-institutional-experiences-in-bosnia-and-herzegovina
#19
Nermina Beslic, Renata Milardovic, Amera Sadija, Sejla Ceric, Zeljka Raic
INTRODUCTION: Myocardial perfusion imaging (MPI) is widely used in the evaluation of known and suspected coronary artery disease (CAD). Imaging of heart in stress and rest enables the comparison of myocardial uptake of radiotracer in proportion to the needs and coronary flow, which is used for detection of perfusion defects. Exercise stress and pharmacologic agents are used for the stressing purpose. Novel pharmacologic stressor regadenoson is A2A selective adenosine agonist, which selectively binds to the adenosine receptors in coronary arteries causing coronary dilatation...
December 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28050863/incremental-prognostic-value-of-spect-mpi-in-chronic-kidney-disease-a-reclassification-analysis
#20
Amjad M Ahmed, Waqas T Qureshi, Wesley T O'Neal, Fatima Khalid, Mouaz H Al-Mallah
BACKGROUND: Traditional cardiovascular (CV) risk factors have limited predictive value of CV mortality in patients with chronic kidney disease (CKD, creatinine clearance less than 60 mL/minute per 1.73 m(2)). The aim of this study was to evaluate incremental and independent prognostic value of single-photon emission computerized tomography-myocardial perfusion imaging (SPECT-MPI) across continuum of renal function. METHODS: We retrospectively studied 11,518 (mean age, 65 ± 12 years; 52% were men) patients referred for a clinical indication of SPECT-MPI between April 2004 and May 2009...
January 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
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