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https://www.readbyqxmd.com/read/27912978/tap-water-iontophoresis-in-the-treatment-of-pediatric-hyperhidrosis
#1
Haitham Dagash, Sinead McCaffrey, Katie Mellor, Agnes Roycroft, Ingrid Helbling
AIM OF THE STUDY: The treatment options for localized hyperhidrosis include antiperspirants, anticholinergics, iontophoresis, botulinum toxin and surgery. Tap water iontophoresis (TWI) involves immersing the affected area in tap water and passing a small electrical current through the area. Our aim was to assess the success of this therapy in a pediatric cohort. METHODS: Retrospective case note review of all patients younger than 18years who underwent TWI between 2002 and 2015...
November 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27894764/thoracoscopic-bilateral-t3-sympathectomy-for-primary-focal-hyperhidrosis-in-children
#2
Pablo Laje, Kali Rhodes, Leanne Magee, Mary Kate Klarich
AIM OF THE STUDY: Present our experience in the surgical treatment of primary focal hyperhidrosis of the hands by thoracoscopic bilateral T3 sympathectomy in pediatric patients. METHODS: Retrospective chart review of all patients operated between 2013 and 2015. RESULTS: We operated and included in the study 28 patients, 22 females and 6 males. Mean age was 14 (6-21) years. All patients had previously tried at least one form of medical therapy with no success...
November 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27893541/treatment-of-palmar-hyperhidrosis-with-needle-injection-versus-low-pressure-needle-free-jet-injection-of-onabotulinumtoxina-an-open-label-prospective-study
#3
Sophie Vadeboncoeur, Vincent Richer, Mélissa Nantel-Battista, Antranik Benohanian
BACKGROUND: OnabotulinumtoxinA (OnabotA) injections are effective to treat palmar hyperhidrosis (HH) but are quite painful. OBJECTIVE: To evaluate efficacy and pain of OnabotA injection using a needle-free jet apparatus compared with the traditional needle injection to treat palmar HH. METHODS: Twenty patients were recruited for a prospective open-label study. Their right hand was injected with 1% lidocaine with a jet injector, after which OnabotA was injected with a needle...
November 23, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27889103/cardiac-autonomic-changes-after-thoracic-sympathectomy-a-prospective-randomized%C3%A2-study
#4
Alfonso Fiorelli, Giovanni Messina, Paolo Chiodini, Saveria Costanzo, Andrea Viggiano, Marcellino Monda, Giovanni Vicidomini, Mario Santini
BACKGROUND: We evaluated whether cardiac autonomic changes could be associated with different extent of sympathetic nerve resection in the management of essential palmar hyperhidrosis. METHODS: Sixty patients with essential palmar hyperhidrosis were randomly allocated to undergo excision of T3 ganglia (sympathicectomy group; n = 30) or to interruption of sympathetic chain at the T2 to T3 level with ganglion sparing (sympathicotomy group; n = 30). Time and frequency domains were measured with a 24-Holter monitor during daytime, nighttime, and 24-hour periods at different interval points (7 days before operation; 24 hours; and 1, 3, and 6 months later), and the differences were statistically compared...
November 23, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27881089/abnormal-primary-and-permanent-dentitions-with-ectodermal-symptoms-predict-wnt10a-deficiency
#5
Birgitta Bergendal, Johanna Norderyd, Xiaolei Zhou, Joakim Klar, Niklas Dahl
BACKGROUND: The WNT10A protein is critical for the development of ectodermal appendages. Variants in the WNT10A gene may be associated with a spectrum of ectodermal abnormalities including extensive tooth agenesis. METHODS: In seven patients with severe tooth agenesis we identified anomalies in primary dentition and additional ectodermal symptoms, and assessed WNT10A mutations by genetic analysis. RESULTS: Investigation of primary dentition revealed peg-shaped crowns of primary mandibular incisors and three individuals had agenesis of at least two primary teeth...
November 24, 2016: BMC Medical Genetics
https://www.readbyqxmd.com/read/27879523/prevalence-of-multifocal-primary-hyperhidrosis-and-symptom-severity-over-time-results-of-a-targeted-survey
#6
Dee Anna Glaser, Angela M Ballard, Niquette L Hunt, Lisa J Pieretti, David M Pariser
BACKGROUND: There is a paucity of data on the prevalence of multifocal primary hyperhidrosis and changes in hyperhidrosis severity over time. OBJECTIVE: The goal of this study was to better understand multifocal primary hyperhidrosis, prevalence and distribution of hyperhidrosis by focal site, age of onset of symptoms by focal area, and change in hyperhidrosis severity over time and with seasons. MATERIALS AND METHODS: The International Hyperhidrosis Society, through an unrestricted research grant from Revance Therapeutics, conducted an online survey of registered visitors to its Web site...
December 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27878939/botulinum-toxin-a-for-palmar-hyperhidrosis-assessment-with-sympathetic-skin-responses-evoked-by-train-of-stimuli
#7
J Y Al-Hashel, D Youssry, H M Rashaed, T Shamov, R T Rousseff
Objective assessment of the effect of botulinum toxin A (BT) treatment in primary palmar hyperhidrosis (PH) is attempted by different methods. We decided to use for this purpose sympathetic skin responses evoked by train of stimuli (TSSR). Twenty patients with severe PH (five female, median age 24, range 18-36) were examined regularly over 3 months after receiving 50 UI BT in each palm. TSSR were recorded from the palms after sensory stimulation by a train of three supramaximal electric pulses 3 millisecond apart...
November 23, 2016: Autonomic & Autacoid Pharmacology
https://www.readbyqxmd.com/read/27865628/the-genesis-and-presentation-of-anxiety-in-disorders-of-autonomic-over-excitation
#8
Andrew P Owens, David A Low, Valeria Iodice, Hugo D Critchley, Christopher J Mathias
INTRODUCTION: We investigated the genesis and presentation of previously-reported anxiety in disorders of autonomic overexcitation in relation to interoception, body vigilance and trauma to test our hypothesis that patients with the postural tachycardia syndrome (PoTS), vasovagal syncope (VVS) and essential hyperhidrosis (EH) represent atypical anxiety phenotypes in whom affective symptoms are more related to apprehension and vigilance of physiological (interoceptive) feedback than neurotic or trauma-related factors...
October 19, 2016: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/27859607/a-new-method-for-evaluation-of-the-autonomic-nervous-system-in-patients-with-idiopathic-hyperhidrosis-systolic-blood-pressure-and-heart-rate-recovery-after-graded-exercise
#9
Y I Alihanoglu, B S Yildiz, I D Kilic, A Saricopur, M Oncu, I Buber, L Tasli, H Evrengul
BACKGROUND: Idiopathic hyperhidrosis (IH) is characterized by excessive and uncontrolled production of sweat, mainly localized to the soles, palms, axillae and craniofacial area. Although IH is a disease concerning the autonomic nervous system, it is not clear yet whether this dysfunction is local or systemic. OBJECTIVE: To evaluate the autonomic control of cardiovascular system by measuring values of heart rate recovery (HRR) and systolic blood pressure recovery (SBPR) obtained at various time intervals after maximal graded exercise treadmill testing in patients with IH compared with controls...
December 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27847661/thermoregulatory-instability-in-childhood-linking-the-normal-brain-to-hypothalamic-storm
#10
William Alves Martins, Rafael do Amaral Cristovam, Helena Fussiger, Viviane Maria Vedana, Marta Hemb
Central core temperature is tightly controlled by hypothalamic centers, a feature that makes sudden changes in body temperature very unusual. A dysfunction of these hypothalamic pathways leads to Shapiro's syndrome, comprising spontaneous hypothermia, hyperhidrosis, and corpus callosum dysgenesis. Although it may affect any age, usually it presents in childhood. Variants to this syndrome with completely normal brain anatomy have been consistently reported, expanding the clinical spectrum of the syndrome. Herein, we report the case of a 4-year-old girl with Shapiro's syndrome and unaffected corpus callosum...
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/27787745/current-and-emerging-medical-therapies-for-primary-hyperhidrosis
#11
REVIEW
Daniel A Grabell, Adelaide A Hebert
Hyperhidrosis is defined as the production of sweat beyond what is physiologically necessary to maintain thermal homeostasis. This disease state may (and typically does) have a significant impact on the patient's quality of life. Medications including antiperspirants, anticholinergics, and botulinum toxin have been shown to be effective in the management of hyperhidrosis. Several medical device technologies have also proven to be effective. This review article will explore the current and emerging pharmacological and medical device treatments for hyperhidrosis and provide a framework for treating patients who suffer with primary forms of hyperhidrosis...
October 27, 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27782761/comparison-of-microwave-ablation-botulinum-toxin-injection-and-liposuction-curettage-in-the-treatment-of-axillary-hyperhidrosis-a-systematic-review
#12
Marwan W Nasr, Samer F Jabbour, Roger N Haber, Elio G Kechichian, Lena El Hachem
BACKGROUND: Primary focal axillary hyperhidrosis is a disorder of excessive sweating that can strongly impact quality of life. OBJECTIVE: To compare microwave ablation, botulinum toxin injection and liposuction-curettage in the treatment of primary axillary hyperhidrosis based on subjective and objective criteria. METHODS: A systematic review of the literature published in French or English between January 1(st) 1991 and February 1(st) 2015 was completed using PubMed and Embase databases...
October 26, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27781949/current-and-future-perspectives-on-the-major-depressive-disorder-focus-on-the-new-multimodal-antidepressant-vortioxetine
#13
Laura Orsolini, Carmine Tomasetti, Alessandro Valchera, Felice Iasevoli, Elisabetta Filomena Buonaguro, Michele Fornaro, Annastasia L C Fiengo, Giovanni Martinotti, Federica Vellante, Ilaria Matarazzo, Roberta Vecchiotti, Giampaolo Perna, Marco Di Nicola, Alessandro Carano, Andrea de Bartolomeis, Massimo Di Giannantonio, Domenico De Berardis
BACKGROUND: Vortioxetine (VRX) is a multimodal antidepressant that acts as serotonin (5¬HT) transporter inhibitor as well as 5¬HT3A and 5¬HT7 receptors antagonist, 5¬HT1A and 5¬HT1B receptors partial agonist. It was recently approved in the US and the EU for the treatment of adult patients with Major Depressive Disorder (MDD). OBJECTIVE: The present article aims at systematically reviewing findings of the published and unpublished research on the pharmacological properties, efficacy, safety and tolerability of oral VRX in the treatment of major depressive disorder (MDD)...
October 25, 2016: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/27780770/residual-limb-hyperhidrosis-managed-by-botulinum-toxin-injections-enhanced-by-the-iodine-starch-test-a-case-report
#14
Colby R Hansen, Bradeigh Godfrey
: Hyperhidrosis of the residual limb is a common condition affecting patients with amputations. The iodine-starch test is used by dermatologists to identify focal areas of hyperhidrosis before treatment with botulinum toxin. Here, we describe a case of a patient with a transtibial amputation with moderate-to-severe hyperhidrosis who received intradermal botulinum toxin injections to treat residual limb hyperhidrosis, with particular emphasis given to the utility of the iodine-starch test in managing this common condition...
October 22, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27755171/microneedling-a-comprehensive-review
#15
Angela Hou, Brandon Cohen, Adele Haimovic, Nada Elbuluk
BACKGROUND: Microneedling is a minimally invasive procedure that uses fine needles to puncture the epidermis. The microwounds created stimulate the release of growth factors and induce collagen production. The epidermis remains relatively intact, therefore helping to limit adverse events. The indications for microneedling therapy have grown significantly, and it is becoming a more widely used treatment in dermatology. OBJECTIVE: A comprehensive review of microneedling in human subjects and its applications in dermatology...
October 13, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27744497/hyperhidrosis-an-update-on-prevalence-and-severity-in-the-united-states
#16
James Doolittle, Patricia Walker, Thomas Mills, Jane Thurston
Current published estimates of the prevalence of hyperhidrosis in the United States are outdated and underestimate the true prevalence of the condition. The objectives of this study are to provide an updated estimate of the prevalence of hyperhidrosis in the US population and to further assess the severity and impact of sweating on those affected by the condition. For the purposes of obtaining prevalence, a nationally representative sample of 8160 individuals were selected using an online panel, and information as to whether or not they experience hyperhidrosis was obtained...
December 2016: Archives of Dermatological Research
https://www.readbyqxmd.com/read/27692207/hyperhidrosis
#17
Peter B Licht
No abstract text is available yet for this article.
November 2016: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/27692206/management-of-plantar-hyperhidrosis-with-endoscopic-lumbar-sympathectomy
#18
Roman Rieger
Primary plantar hyperhidrosis is defined as excessive secretion of the sweat glands of the feet and may lead to significant limitations in private and professional lifestyle and reduction of health-related quality of life. Conservative therapy measures usually fail to provide sufficient relieve of symptoms and do not allow long-lasting elimination of hyperhidrosis. Endoscopic lumbar sympathectomy appears to be a safe and effective procedure for eliminating excessive sweating of the feet and improves quality of life of patients with severe plantar hyperhidrosis...
November 2016: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/27692204/less-common-side-effects-of-sympathetic-surgery
#19
Lyall A Gorenstein, Mark J Krasna
Because of video-assisted thoracic technology and increased patient awareness of treatment options for palmar hyperhidrosis, endoscopic thoracic sympathectomy (ETS) has become a well-accepted treatment for this disorder. Video assistance affords excellent visualization of thoracic anatomy, which allows the procedure to be done quickly with few complications. However, despite the ease of performing ETS, complications can occur unless thoracic anatomy and physiology are well-understood. Awareness of possible intraoperative and postoperative complications is essential if this procedure is gong to be performed safely...
November 2016: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/27692203/management-of-compensatory-sweating-after-sympathetic-surgery
#20
Nelson Wolosker, José Ribas Milanez de Campos, Juliana Maria Fukuda
Compensatory hyperhidrosis (HH) is the most common and feared side effect of thoracic sympathectomy, because patients with severe forms have their quality of life greatly impaired. The most well-known factors associated with compensatory HH are extension of manipulation of the sympathetic chain, level of sympathetic denervation, and body mass index. Technical developments as well as the proper selection of patients for surgery have been crucial in reducing the occurrence of severe forms of compensatory HH. Therapeutic options include topical agents, botulinum toxin, systemic anticholinergics, clip removal, and sympathetic chain reconstruction, although the efficacy is not well-established for all the methods...
November 2016: Thoracic Surgery Clinics
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