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https://www.readbyqxmd.com/read/28422886/comparison-of-t2-and-t3-sympathectomy-for-compensatory-sweating-on-palmar-hyperhidrosis
#1
Atila Turkyilmaz, Sami Karapolat, Kubra Nur Seyis, Celal Tekinbas
BACKGROUND: An otherwise successfully performed endoscopic thoracic sympathectomy (ETS) to treat palmar hyperhidrosis (PH) often has a serious side effect: compensatory sweating (CS). This side effect occurs in other parts of the body to a disturbing extent. The objective of this study is to determine whether there is a relationship between the level of ETS performed on patients with PH, and the occurrence and severity of postoperational CS. METHODS: Between January 2014 and January 2015, ETS procedures were performed on 25 randomly selected consecutive subjects (group A) at T2 level, and on another 25 subjects (group B) at T3 level, who all felt severely handicapped due to PH...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28421149/eccrine-nevus-presenting-with-umbilical-discharge-a-case-report-and-review-of-the-literature
#2
Farahnaz Bidari-Zerehpoosh, Shahram Sabeti, Farid Arman, Hania Shakeri
Eccrine nevus is a rare skin lesion with protean manifestations like hyperhidrosis, discolored nodules, papules, and so forth, which has been reported in various anatomic parts of the body including the forearm, leg, thigh, back, and coccyx. Our patient was a 26-year-old male, who presented with increasing colorless and odorless episodic umbilical discharge. First impression for the patient was an umbilical sinus and the patient underwent surgery. Histopathological study revealed the lesion to be an eccrine nevus of the umbilicus...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/28401702/confirmatory-factor-analysis-of-the-sleep-disturbance-scale-for-children-sdsc-in-a-clinical-sample-of-children-and-adolescents
#3
Angela M Marriner, Carmela Pestell, Donna M Bayliss, Marie McCann, Romola S Bucks
The Sleep Disturbance Scale for Children was developed as a parent-report measure to screen for sleep disturbances within the preceding 6 months. Notably, the scale was developed using a sample of typically developing children and children with sleep disorders. The aim of this study was to factor analyse the Sleep Disturbance Scale for Children using a clinical sample of children with a range of neuropsychological conditions and co-morbidities, and determine whether the original six-factor structure was retained...
April 12, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28389800/optimal-targeting-of-sympathetic-chain-levels-for-treatment-of-palmar-hyperhidrosis-an-updated-systematic-review
#4
Hai-Wei Sang, Guo-Liang Li, Peng Xiong, Ming-Chuang Zhu, Min Zhu
BACKGROUND: Palmar hyperhidrosis involves excessive sweating of the palms, with no known etiology. Endoscopic thoracic sympathectomy (ETS) is a safe and effective treatment for palmar hyperhidrosis, but compensatory hyperhidrosis is a common complication after ETS, leading to reduced patient satisfaction and postoperative quality of life. However, the appropriate level of the sympathetic chain to target with ETS to achieve maximum efficacy and reduce the risk of compensatory hyperhidrosis (CH) is controversial...
April 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28388990/oral-oxybutynin-for-local-and-multifocal-hyperhidrosis-a-multicenter-study
#5
T Toledo-Pastrana, J Márquez-Enríquez, J F Millán-Cayetano
No abstract text is available yet for this article.
April 4, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28388720/new-uses-of-abobotulinumtoxina-in-aesthetics
#6
Joel Schlessinger, Erin Gilbert, Joel L Cohen, Joely Kaufman
BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance...
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28366656/percutaneous-ct-guided-sympathicolysis-with-radiofrequency-for-the-treatment-of-palmar-hyperhidrosis
#7
Paula García-Barquín, Jesús Dámaso Aquerreta Beola, José María Bondía Gracía, Agustín España Alonso, Juan Pérez Cajaraville, Pablo Bartolomé Leal, Gorka Bastarrika
PURPOSE: To evaluate the benefits of computed tomography (CT)-guided percutaneous sympathicolysis with radiofrequency in patients with primary palmar hyperhidrosis (PPHH) in terms of safety, patient satisfaction, and short- and long-term efficacy. MATERIALS AND METHODS: A total of 139 procedures in 108 patients (mean age, 29.89 y ± 10.94), including 50 men and 58 women, with PPHH and therapy-resistance of nonsurgical treatments were retrospectively analyzed. Treatment was performed bilaterally at T2, T3, and T4 levels, reaching 90°C during 8 minutes...
March 30, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28329602/glycopyrrolate-induced-craniofacial-compensatory-hyperhidrosis-successfully-treated-with-oxybutynin-report-of-a-novel-adverse-effect-and-subsequent-successful-treatment
#8
Megan E Prouty, Ryan Fischer, Deede Liu
Hyperhidrosis, or abnormally increased sweating, is a condition that may have a primary or secondary cause. Usually medication- induced secondary hyperhidrosis manifests with generalized, rather than focal sweating. We report a 32-year-old woman with a history of palmoplantar hyperhidrosis for 15 years who presented for treatment and was prescribed oral glycopyrrolate. One month later, the palmoplantar hyperhidrosis had resolved, but she developed new persistent craniofacial sweating. After an unsuccessful trial of clonidine, oxybutynin resolved the craniofacial hyperhidrosis...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28318360/axillary-hyperhidrosis-a-focused-review
#9
Jason E Sammons, Amor Khachemoune
Axillary hyperhidrosis is characterized by an increased amount of sweat production, localized to the armpits, to compensate for environmental conditions and to control thermoregulation. It affects about 3.12% of the US population. It has a significant effect on one's psychological and physical health, as well as one's occupational life. The objective of this paper is to review the epidemiology, clinical presentation, pathophysiology, histology, and genetics, and management and treatment of axillary hyperhidrosis...
March 20, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28314788/the-parp-inhibitor-veliparib-can-be-safely-added-to-bendamustine-and-rituximab-and-has-preliminary-evidence-of-activity-in-b-cell-lymphoma
#10
Jacob D Soumerai, Andrew D Zelenetz, Craig Moskowitz, M Lia Palomba, Paul A Hamlin, Ariela Noy, David J Straus, Alison J Moskowitz, Anas Younes, Matthew J Matasar, Steven Horwitz, Carol Portlock, Jason Konner, Mrinal M Gounder, David M Hyman, Martin H Voss, Matthew G Fury, Devika Gajria, Richard D Carvajal, Alan L Ho, Jan H Beumer, Brian Kiesel, Zhigang Zhang, Alice Chen, Richard F Little, Christine Jarjies, Thu O Dang, Fallon France, Nishant Mishra, John F Gerecitano
PURPOSE: The PARP inhibitor veliparib enhances the cytotoxicity of alkylating agents. This phase 1 study evaluated veliparib with the bifunctional alkylator bendamustine (VB) in patients with relapsed/refractory lymphoma, multiple myeloma, and solid malignancies, with a cohort expansion of VB with rituximab (VBR) in patients with B-cell lymphomas. EXPERIMENTAL DESIGN: This dose-escalation study evaluated safety, pharmacokinetics and preliminary efficacy of veliparib (20-400 mg BID, days 1-7 of 28-day cycle) and bendamustine (70 and 90 mg/m2 IV, days 1 and 2)...
March 17, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28300854/randomized-placebo-and-active-controlled-crossover-study-of-the-safety-and-efficacy-of-thvd-102-a-fixed-dose-combination-of-oxybutynin-and-pilocarpine-in-subjects-with-primary-focal-hyperhidrosis
#11
David M Pariser, Janakan Krishnaraja, Thomas M Tremblay, R Michael Rubison, Ted W Love, Benjamin F McGraw
BACKGROUND: While muscarinic antagonists (anticholinergics) have shown efficacy in treating primary focal hyperhidrosis (PFH), side effects - most commonly dry mouth - are intolerable for most patients. THVD-102, a fixed-dose combination product has been developed combining oxybutynin, a muscarinic antagonist, and pilocarpine, a muscarinic agonist. The pilocarpine is at a dose level and release profile optimized to correct salivary flow impaired by oxybutynin yet not interfere with the therapeutic muscarinic antagonist effect of oxybutynin upon the sweat glands...
February 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28299626/efficacy-and-safety-of-escitalopram-in-treatment-of-severe-depression-in-chinese-population
#12
Tianmei Si, Gang Wang, Fude Yang, Yiru Fang, Maosheng Fang, Jijun Li, Jicheng Dong, Xinhua Shen, Jianmin Zhuo, Qing Rui, Jinan Wang, Hu Cuili
Severe depression accounts for one-third of depressed patients. Increasing severity of depression usually hinders patients from achieving remission. This study evaluated the efficacy and safety of escitalopram in acute-phase treatment of severe major depressive disorder (MDD). A total of 225 participants with severe MDD (Diagnostic and Statistical Manual of Mental Disorders, 4th Edition criteria), with a current depressive episode and Montgomery-Asberg Depression Rating Scale (MADRS) score of ≥30 were enrolled...
March 15, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28295246/pourfour-du-petit-syndrome-associated-with-right-eye-pressure
#13
Randolph W Evans, Adam Garibay, Rod Foroozan
Pourfour du Petit (PDP) syndrome is a rare disorder characterized by ipsilateral mydriasis, eyelid retraction, and hemifacial hyperhidrosis caused by hyperactivity of the ipsilateral oculosympathetic pathway. A case is presented of PDP syndrome associated with likely ipsilateral occipital neuralgia. We review the causes and co-morbidities and the clinical features of PDP.
March 13, 2017: Headache
https://www.readbyqxmd.com/read/28284421/microwave-treatment-for-axillary-hyperhidrosis-and-bromhidrosis
#14
I Sánchez-Carpintero, A Martín-Gorgojo, R Ruiz-Rodríguez
Axillary hyperhidrosis (AH) and bromhidrosis are common causes of consultation in dermatology. Currently, the most widely prescribed treatment for AH is botulinum toxin, a very effective but temporary option; it is totally ineffective in bromhidrosis. Sympathectomy is an increasingly infrequent choice of treatment due to the high incidence of compensatory hyperhidrosis. We describe the treatment of AH and bromhidrosis with a novel microwave device that can fibrose eccrine and apocrine glands, achieving possibly permanent results...
March 8, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28282662/r3-versus-r4-thoracoscopic-sympathectomy-for-severe-palmar-hyperhidrosis
#15
Wenxiong Zhang, Yiping Wei, Han Jiang, Jianjun Xu, Dongliang Yu
Background Thoracoscopic sympathectomy (TS) was the preferred surgical treatment for palmar hyperhidrosis (PH), but postoperative complications such as compensatory sweating (CS) were common. This study was projected to compare R3 versus R4 TS for treating severe PH. Methods From April 2009 and March 2015, 106 consecutive patients with severe PH underwent bilateral R3 (n = 62) or R4 (n = 44) TS at The Second Affiliated Hospital of Nanchang University. The patients were followed up to evaluate symptom resolution, postoperative complications, satisfaction level, and severity of CS...
March 10, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28282661/influence-of-body-mass-index-on-compensatory-sweating-in-patients-after-thoracic-sympathectomy-due-to-palmar-hyperhidrosis
#16
Lukasz Dobosz, Natalia Cwalina, Tomasz Stefaniak
Background Thoracic sympathectomy (TS) is one of the most effective methods of treatment of primary hyperhidrosis. One of the side effects of this procedure is compensatory sweating (CS). Objective The aim of our study was to evaluate the influence of body mass index (BMI) on CS in patients after TS due to palmar hyperhidrosis. Methods Data from 157 patients with palmar hyperhidrosis who underwent TS were collected. The patients were subsequently divided in two groups according to their initial BMI: group A, BMI < 25 kg/m(2), and group B, BMI ≥ 25 kg/m(2)...
March 10, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28281850/a-systematic-review-of-microwave-based-therapy-for-axillary-hyperhidrosis
#17
Tzu-Herng Hsu, Yu-Tsung Chen, Yu-Kang Tu, Chien-Nien Li
OBJECTIVE: To systematically analyse the literature on the use of the microwave-based device for subdermal thermolysis of the axilla and its efficacy for the treatment of axillary hyperhidrosis. MATERIALS AND METHODS: A systematic review was conducted using PubMed, Embase, SCOPUS and Cochrane databases on 2 June 2016. The inclusion criteria including: (1) studies with human subjects, (2) full-text articles published in English, (3) a microwave-based device used to treat axillary hyperhidrosis and (4) trials that precisely evaluated axillary hyperhidrosis...
March 10, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28273934/a-systematic-review-and-meta-analysis-of-t2-t3-or-t4-to-evaluate-the-best-denervation-level-for-palmar-hyperhidrosis
#18
Wenxiong Zhang, Dongliang Yu, Yiping Wei, Jianjun Xu, Xiaoqiang Zhang
We systematically reviewed and compared the clinical outcomes of thoracoscopic sympathectomy (TS) at different denervation levels for palmar hyperhidrosis. We searched PubMed, Ovid MEDLINE, EMBASE, Web of Science, ScienceDirect, the Cochrane Library, Scopus and Google Scholar for relevant studies published during 1990-2016. Symptom resolution, patient satisfaction, compensatory sweating (CS), recurrence, dry hands and gustatory sweating were assessed. We selected 13 studies from 2228 for the final analysis...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28273218/comparison-between-high-and-low-levels-thoracic-sympathectomy-for-the-treatment-of-palmar-and-axillary-primary-hyperhidrosis-systematic-review-and-meta-analysis
#19
Gilmar Felisberto Júnior, Cláudio José Rubira, João Paulo Sanches Berumudes, Salum Bueno DA-Silveira-Júnior
Primary hyperhidrosis (PH) is a condition that has a great impact on affected individuals' quality of life, regardless of its location. Its surgical treatment is done through thoracic sympathectomy performed by videothoracoscopy. Standardization of the technique includes section of the sympathetic trunk at different levels, according to the site of symptoms. The aim of this review is to evaluate the efficacy of thoracic sympathectomy through a systematic literature review comparing sympathectomy at different levels of the sympathetic chain...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28244893/methadone-induced-hyperhidrosis-treated-with-oxybutynin
#20
Joe Hong, Jooyeon Lee, Holly Totouom-Tangho, Norma Ramos Dunn, Ronnie Gorman Swift
OBJECTIVES: This case report aims to help healthcare providers and methadone clinic patients to recognize one of the less recognized adverse effects of methadone, hyperhidrosis, and to suggest oxybutynin as a possible solution. METHODS: A 35-year-old man on methadone maintenance therapy presented with excessive sweating, which began promptly after methadone was introduced. Urine toxicology was conducted every 2 weeks to rule out other illicit substances that may have contributed to the sweating...
February 27, 2017: Journal of Addiction Medicine
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