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https://www.readbyqxmd.com/read/29786953/iatrogenic-botulism-outbreak-in-egypt-due-to-a-counterfeit-botulinum-toxin-a-preparation-a-descriptive-series-of-patient-features-and-outcome
#1
Eman Abdel Monaem Abdel Rashid, Nashwa Mohamed El-Mahdy, Huda Shehata Kharoub, Ahmed Salah Gouda, Naglaa Ahmed ElNabarawy, Bruno Mégarbane
Iatrogenic botulism resulting from the substantial increase in use of botulinum neurotoxin type-A (BoNT-A) treatment is rarely reported. We aimed to describe a large iatrogenic botulism outbreak in Egypt in June-July 2017. Nine patients developed botulism after receiving intramuscular injections of BoNT-A (dose: 200-300 IU) to treat cerebral palsy (N=7), spastic dystonia (N=1), and hyperhidrosis (N=1). Detailed findings were available in 5/9 cases. Patients were admitted to the hospital 5-10 days after the BoNT-A injection...
May 22, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29784606/associated-with-ischemic-stroke-risk-reduction-after-endoscopic-thoracic-sympathectomy-for-palmar-sweating
#2
Chun-Gu Cheng, Chun-An Cheng, Wu-Chien Chien, Chi-Hsiang Chung, Jiunn-Tay Lee
BACKGROUND: Endoscopic thoracic sympathectomy (ETS) was performed to cure palmar hyperhidrosis (PH). After ETS, blood pressure decreased, and cerebral flow velocity increased within 1 month. However, no studies distinguish between subsequent ischemic and hemorrhagic stroke following ETS for PH. The association between stroke type and PH after ETS must be evaluated. METHODS: We surveyed newly diagnosed patients with PH using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnostic code 708...
May 18, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29782305/tatami-mats-a-source-of-pitted-keratolysis-in-a-martial-arts-athlete
#3
Anamaria Balić, Zrinka Bukvić Mokos, Branka Marinović, Daniela Ledić Drvar
Dear Editor, Pitted keratolysis (PK), also known as keratosis plantaris sulcatum, is a non-inflammatory, bacterial, superficial cutaneous infection, characterized by many discrete superficial crateriform ''pits'' and erosions in the thickly keratinized skin of the weight-bearing regions of the soles of the feet (1). The disease often goes unnoticed by the patient, but when it is noticed it is because of the unbearable malodor and hyperhidrosis of the feet, which are socially unacceptable and cause great anxiety to many of the patients...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29776420/the-relationship-between-preoperative-psychological-evaluation-and-compensatory-sweating
#4
Huai-Yu Wang, Yan-Jun Zhu, Jie Liu, Li-Wei Li, Ying-Hui Liu
BACKGROUND: This study analyzes the relationship between preoperative psychological states of primary palmar hyperhidrosis patients and postoperative compensatory sweating. METHODS: We evaluated the psychological states of patients with primary palmar hyperhidrosis who received sympathectomy in our hospital from 2016 to 2017. The relationship between preoperative psychological states and postoperative compensatory sweating were assessed using Spearman's rank-order correlation...
May 18, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29771216/mindfulness-based-cognitive-hypnotherapy-and-skin-disorders
#5
Philip D Shenefelt
Mindfulness-based cognitive hypnotherapy integrates mindfulness, cognitive-behavioral therapy, and hypnotherapy to improve physical, emotional, mental, and/or spiritual aspects of skin disorders. Meditation, including mindfulness meditation, and hypnosis both utilize trance phenomena to help produce focalization and specific improvements in skin disorders through psycho-neuro-endocrine-immunologic mechanisms. Hypnosis, cognitive hypnotherapy, focused meditation, and mindfulness meditation are discussed with respect to improving various skin disorders including acne, acne excoriée, alopecia areata, atopic dermatitis, congenital ichthyosiform erythroderma, dyshidrotic dermatitis, erythema nodosum, erythromelalgia, furuncles, glossodynia, herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus, neurodermatitis, nummular dermatitis, postherpetic neuralgia, prurigo nodularis, pruritus, psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo...
July 2018: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/29765968/histopathological-evidence-of-the-efficacy-of-percutaneous-ethanol-injection-in-the-treatment-of-axillary-osmidrosis-a-promising-new-procedure
#6
Ali Asilian, Bahareh Abtahi-Naeini, Masoom Shahbazi
Axillary osmidrosis (AO) is a common disease, affecting patients psychologically and influencing their quality of life. The medical approach to AO remains controversial, ranging from conservative medical to surgical choices. We describe the successful treatment of AO and axillary hyperhidrosis (AH) using percutaneous ethanol injection (PEI) in a 30-year-old patient with AO and AH who did not respond to topical and systemic medication. We also describe the clinical efficacy of PEI by presenting our experience with histopathological evidence of necrosis of the sweat glands...
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29760304/metyrapone-responsive-ectopic-acth-secreting-pheochromocytoma-with-a-vicious-cycle-via-a-glucocorticoid-driven-positive-feedback-mechanism
#7
Minako Inoue, Ken Okamura, Chie Kitaoka, Fumio Kinoshita, Ryo Namitome, Udai Nakamura, Masaki Shiota, Kenichi Goto, Toshio Ohtsubo, Kiyoshi Matsumura, Yoshinao Oda, Masatoshi Eto, Takanari Kitazono
In ectopic ACTH-secreting pheochromocytoma, combined ACTH-driven hypercortisolemia and hyper-catecholaminemia are serious conditions, which can be fatal if not diagnosed and managed appropriately, especially when glucocorticoid-driven positive feedback is suggested with a high ACTH/cortisol ratio. A 46-year-old man presented with headache, rapid weight loss, hyperhidrosis, severe hypertension and hyperglycemia without typical Cushingoid appearance. Endocrinological examinations demonstrated elevated plasma and urine catecholamines, serum cortisol and plasma ACTH...
May 15, 2018: Endocrine Journal
https://www.readbyqxmd.com/read/29740900/adjusting-oral-oxybutynin-medication-for-hyperhidrosis-to-reflect-seasonal-temperature-variations
#8
Javier Del Boz, José Francisco Millán-Cayetano, Pablo García-Montero, Cristina García-Harana, Francisco Rivas-Ruiz, Magdalena de Troya-Martín
Most studies of oral oxybutynin (OOx) for the treatment of hyperhidrosis (HH) have assumed a stable treatment protocol, without taking into account adverse effects (AE) or seasonal variations in temperature. The objective is to evaluate adjusting the dose of OOx according to the time of year. Prospective study of patients who began OOx for HH between 2007 and 2017, and maintained treatment for at least 1 year, with a progressively increasing dose was performed. All patients were recommended to vary the dose of medication according to the time of year...
May 8, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29739022/efficacy-of-miniuniportal-video-assisted-thoracoscopic-selective-sympathectomy-ramicotomy-for-the-treatment-of-severe-palmar-and-axillar-hyperhidrosis
#9
Ali Akil, Michael Semik, Stefan Fischer
BACKGROUND:  Video-assisted thoracoscopic surgery (VATS) clipping of the sympathetic branch has become the standard approach for the treatment of essential hyperhidrosis when conservative treatment failed. However, this is associated with relevant potential complications such as postoperative compensatory sweating and recurrent sweating. We report the outcome after selective sympathectomy (ramicotomy) through a miniuniportal VATS approach in patients with therapy-refractory palmar and/or axillary hyperhidrosis...
May 8, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29715706/needlescopic-video-assisted-thoracic-bilateral-t4-sympathicotomy-for-the-treatment-of-primary-palmar-hyperhidrosis-an-analysis-of-200-cases
#10
Xing Feng, Xiaoling Xiong, Er Jin, Wen Meng
BACKGROUND:  Primary palmar hyperhidrosis (PPH) is featured by aberrantly perspiration of the hands, which may bring a lot of inconvenience to patient's daily life and work. The purpose of this study is to summarize the clinical effect of needlescopic video-assisted thoracic bilateral T4 sympathicotomy for the treatment of PPH. PATIENTS AND METHODS:  Between January 2009 and March 2014, 200 patients received needlescopic video-assisted thoracic bilateral T4 sympathicotomy...
May 1, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29707303/a-long-term-evaluation-of-postoperative-moist-hands-after-r4-r4-5-sympathectomy-for-primary-palmar-hyperhidrosis
#11
Wenhan Weng, Yanguo Liu, Jianfeng Li, Guanchao Jiang, Jun Liu, Jun Wang
Background: Thoracoscopic R4 sympathectomy has been recommended as a safe and effective surgical treatment procedure for primary palmar hyperhidrosis (PPH). However, approximately half of patients presented postoperative moist hands (PMH), and recurrence occurred individually. Therefore, more thorough long-term results should be evaluated. Methods: Between January 2005 and December 2014, 506 consecutive patients with palmar hyperhidrosis treated with either R4 or R4+5 were retrospectively reviewed and followed-up...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29702200/long-term-neurological-and-neuropsychological-complications-of-sulfur-mustard-and-lewisite-mixture-poisoning-in-chinese-victims-exposed-to-chemical-warfare-agents-abandoned-at-the-end-of-wwii
#12
O Isono, A Kituda, M Fujii, T Yoshinaka, G Nakagawa, Y Suzuki
In August 2003, 44 victims were poisoned by chemical warfare agents (CWAs) leaked from five drums that were excavated at a construction site in Qiqihar, Northeast China. The drums were abandoned by the former Japanese imperial army during World War II and contained a mixture of Sulfur mustard (SM) and Lewisite. We carried out a total of six regular check-ups between 2006 and 2014, and from 2008 we added neurological evaluations including neuropsychological test and autonomic nervous function test in parallel with medical follow-up as much as was possible...
April 24, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29701620/use-of-nitrous-oxide-in-dermatology-a-systematic-review
#13
Erica A Brotzman, Laura F Sandoval, Jonathan Crane
BACKGROUND: Many dermatologic procedures are painful and can be distressing to patients. OBJECTIVE: To determine whether nitrous oxide has been used in dermatology and whether literature supports its use in terms of providing analgesia and anxiety associated with dermatologic procedures. METHODS: A search of PubMed and Cochrane databases was conducted through July 15, 2016, to identify studies involving nitrous oxide use in dermatology. RESULTS: Eight studies were identified and reviewed...
May 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29686808/effects-of-warmed-carrier-fluid-on-nefopam-injection-induced-pain
#14
Hyung Rae Cho, Seon Hwan Kim, Jin A Kim, Jin Hye Min, Yong Kyung Lee
Background: Nefopam is a non-opioid, non-steroidal analgesic drug with fewer adverse effects than narcotic analgesics and nonsteroidal anti-inflammatory drugs, and is widely used for postoperative pain control. Because nefopam sometimes causes side effects such as nausea, vomiting, somnolence, hyperhidrosis and injection-related pain, manufacturers are advised to infuse it slowly, over a duration of 15 minutes. Nevertheless, pain at the injection site is very common. Therefore, we investigated the effect of warmed carrier fluid on nefopam injection-induced pain...
April 2018: Korean Journal of Pain
https://www.readbyqxmd.com/read/29681465/botulinum-neurotoxin-a-injection-for-the-treatment-of-epiphora-with-patent-lacrymal-ducts
#15
B Girard, J-M Piaton, P Keller, T H Nguyen
HEADINGS: Retrospective longitudinal study to evaluate the efficacy of botulinum neurotoxin A (BoNT/A) therapy for epiphora with patent lacrimal ducts. BACKGROUND/PURPOSE: BoNT/A has been used since 2000 in axillary hyperhidrosis to reduce sweat secretion. Some isolated cases of hyperlacrimation or crocodile tear syndrome have been treated with BoNT/A on this basis. We report our experience in the treatment of tearing despite patent lacrimal ducts by BoNT/A injection into the lacrimal gland...
April 19, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29681086/a-novel-homozygous-mutation-in-the-slco2a1-gene-causing-pachydermoperiostosis-efficacy-of-hydroxychloroquine-treatment
#16
Annalisa Alessandrella, Roberto Della Casa, Maria Alessio, Jorge Puente Prieto, Pietro Strisciuglio, Daniela Melis
Pachydermoperiostosis (PDP), otherwise known as primary hypertrophic osteoarthropathy, is characterized by digital clubbing, pachydermia and subperiosteal new bone formation. Joint pain, polyarthritis, cutis verticis gyrata, seborrhea, and hyperhidrosis are frequently associated to this condition. We report a 17-year-old boy presented with pain and swelling of knees and ankles, and progressive thickening of skin face with seborrhea from about 4 years. At the admission he also showed digital clubbing of both hands and feet and palmoplantar hyperhidrosis...
May 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29672816/evaluation-of-quality-of-life-functional-assessment-of-chronic-illness-therapy-after-thoracic-sympathectomy-for-palmar-hyperhidrosis
#17
Lukasz Dobosz, Tomasz Stefaniak
BACKGROUND:  Primary hyperhidrosis is a condition that significantly decreases the quality of life (QOL). Thoracic sympathectomy is safe and efficient method of treatment in palmar hyperhidrosis. OBJECTIVE:  The aim of the study was to evaluate the change in QOL in patients with palmar hyperhidrosis who underwent thoracic sympathectomy. METHODS:  The study includes 149 patients (37 men and 112 women) who were treated with bilateral thoracoscopic sympathectomy for primary palmar hyperhidrosis...
April 19, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29669433/investigation-on-aetiological-factors-in-patients-with-hyperhidrosis
#18
Ayşe Akbaş, Fadime Kilinç
BACKGROUND: Hyperhidrosis is a condition where the amount of sweat released to skin surface increases due to the over-active eccrine sweat glands. Hyperhidrosis causes considerable psychosocial distress in affected people. It affects the quality of life and leads to social anxiety disorders. AIMS: No study has been conducted in our country to investigate the epidemiological, clinical and laboratory data of patients with hyperhidrosis. In this study, we aimed to retrospectively investigate the clinical and demographic characteristics, causes of sweating and laboratory findings in patients treated for hyperhidrosis at our outpatient clinic and to compare these data with the literature data...
April 18, 2018: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29665592/-videothoracoscopic-sympathetic-clipping-in-a-patient-with-azygos-lobe-intraoperative-management-to-avoid-potential-complications
#19
Waldemar Schreiner, Iurii Mykoliuk, Wojciech Dudek, Horia Sirbu
INTRODUCTION: Sympathetic clipping in the presence of an azygos lobe is a rare combination. Anatomical relations between the sympathetic trunk and the mesoazygos impede surgical handling and can be associated with potential complications. INDICATION: We report the case of a 25-year old woman with grade III palmoplantar and axillary hyperhidrosis with azygos lobe incidentally found on preoperative chest X-ray. METHOD: Our intraoperative video shows a step-by-step approach to the sympathetic trunk in the presence of the azygos lobe, involving thoracoscopic looping and precise clip application onto the sympathetic trunk...
April 17, 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29662322/a-comparative-trial-of-ice-application-versus-emla-cream-in-alleviation-of-pain-during-botulinum-toxin-injections-for-palmar-hyperhidrosis
#20
Adel Alsantali
Background: Botulinum toxin is a safe and effective therapy for palmar hyperhidrosis, but the associated pain from injections limits the usefulness of this method of treatment. Purpose: To evaluate the efficacy of Eutectic Mixture of Local Anesthetics (EMLA) cream versus ice application in alleviation of pain during botulinum toxin injections for palmar hyperhidrosis. Methods: In this prospective study, 23 patients underwent palm Botox injections to treat their excessive sweating...
2018: Clinical, Cosmetic and Investigational Dermatology
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