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https://www.readbyqxmd.com/read/28345243/dehiscence-of-a-pulmonary-bioprosthesis-with-a-focal-dissection-of-the-pulmonary-artery-in-a-patient-with-congenital-pulmonic-stenosis
#1
Evin Yucel, Ami Bhatt, Christos G Mihos, Brian B Ghoshhajra, Doreen DeFaria Yeh
Pulmonary valve replacement (PVR) is the most common adult congenital cardiac operation performed. Valve degeneration leading to prosthetic stenosis and/or regurgitation is a long-term risk in this population and may be associated with paravalvular leak (PVL). Complications involving the proximal pulmonary artery, including dissection, are less clearly defined. Herein, we report the case of a 30-year-old patient with a history of multiple pulmonary valve interventions secondary to congenital pulmonic stenosis, who developed dehiscence of a bioprosthetic PVR associated with significant paravalvular leak (PVL) and further complicated by a focal dissection of the proximal pulmonary artery...
March 27, 2017: Echocardiography
https://www.readbyqxmd.com/read/28329312/first-experience-with-transfemoral-transcatheter-aortic-valve-implantation-without-prior-balloon-pre-dilatation-using-a-latest-generation-repositionable-and-retrievable-transcatheter-heart-valve%C3%A2
#2
Andreas Schaefer, Eva Harmel, Moritz Seiffert, Daniel Reichart, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: : The aim of this study was to prove technical feasibility and document haemodynamic and clinical outcomes of transcatheter aortic valve implantation (TAVI) with the latest generation repositionable and retrievable Lotus™ transcatheter heart valve (THV) without prior balloon-aortic valvuloplasty (BAV). It has been demonstrated for self-expandable and balloon-expandable THV that implantation without prior BAV is not only feasible and safe but also results in lower fluoroscopy times and amounts of contrast agent while yielding non-inferior haemodynamic and clinical outcome...
February 6, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28322110/the-preferred-viewing-location-in-top-to-bottom-sentence-reading
#3
Rebecca L Johnson, Emma L Starr
The preferred viewing location (PVL) is a robust finding in research on reading that when fixating on a word during normal sentence reading, readers tend to land slightly to the left of the center of the word. This is in contrast to the optimal viewing location (OVL) in single word recognition, which falls at the center of the word. The current study outlines the history of the PVL in eye-tracking since Rayner's 1979 original study, documenting the origins of these conflicting theoretical explanations. In addition, a new study is reported examining whether the PVL can be attributed solely to oculomotor error or a processing advantage by using an experimental manipulation that separates tracking direction (left-to-right reading) and landing position (left-to-right within a word)...
March 21, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28299924/improvement-of-electrical-characteristics-and-stability-of-amorphous-indium-gallium-zinc-oxide-thin-film-transistors-using-nitrocellulose-passivation-layer
#4
Kwan Yup Shin, Young Jun Tak, Won-Gi Kim, Seonghwan Hong, Hyun Jae Kim
In this research, nitrocellulose is proposed as a new material for the passivation layers of amorphous indium gallium zinc oxide thin film transistors (a-IGZO TFTs). The a-IGZO TFTs with nitrocellulose passivation layers (NC-PVLs) demonstrate improved electrical characteristics and stability. The a-IGZO TFTs with NC-PVLs exhibit improvements in field-effect mobility (μFE) from 11.72 ± 1.14 to 20.68 ± 1.94 cm2/Vs, threshold voltage (Vth) from 1.85 ± 1.19 to 0.56 ± 0.35 V, and on/off current ratio (Ion/off) from (5...
March 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28296026/bioprosthetic-mitral-valve-paravalvular-leak-closure-using-intracardiac-echocardiography-guided-three-dimensional-electroanatomic-mapping
#5
Subhi J Al'Aref, Richard B Devereux, Jim W Cheung, Geoffrey Bergman
The development of paravalvular leak (PVL) following surgical replacement of an aortic or mitral valve is an uncommon complication with significant morbidity and mortality. Surgical or percutaneous repair of PVL can be technically challenging. We describe the application of intracardiac echocardiography guided 3-dimensional electroanatomic mapping to facilitate PVL closure in a symptomatic patient with a previously placed bioprosthetic mitral valve. © 2017 Wiley Periodicals, Inc.
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28290167/simple-interrupted-suturing-for-redo-mitral-valve-replacement
#6
Hiroshi Furukawa, Taishi Tamura, Takeshi Honda, Hiroki Takiuchi, Masahiko Kuinose, Kazuo Tanemoto
BACKGROUND: An evaluation was made of the early clinical outcomes and efficacies of simple interrupted suturing (SIS) for redo mitral valve replacement (MVR). METHODS: Among 336 mitral valve surgery patients at the authors' institution between April 2000 and May 2014, a total of 21 redo MVR using SIS (12 women, nine men; mean age 67±11 years; range 32-80 years) participated in the study. Surgical indications for redo MVR were paravalvular leakage (PVL) in 10 patients, prosthetic valve endocarditis in five, mechanical valve thrombosis in three, and structural valve deterioration (SVD) of the bioprosthesis in three...
November 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28283923/characterization-of-staphylococcus-aureus-in-goose-feces-from-state-parks-in-northeast-ohio
#7
Dipendra Thapaliya, Mark Dalman, Jhalka Kadariya, Katie Little, Victoria Mansell, Mohammed Y Taha, Dylan Grenier, Tara C Smith
Staphylococcus aureus can colonize a range of species. Although numerous studies have isolated pathogenic bacteria from wild birds, very little is known regarding S. aureus and their potential to spread methicillin-resistant (MRSA) strains. The objective of this study was to determine the presence and molecular characteristics of S. aureus in geese fecal samples collected from ten state parks across Northeast Ohio (NEO). A total of 182 fecal samples from Canada geese (Branta canadensis) were collected in April 2015...
March 10, 2017: EcoHealth
https://www.readbyqxmd.com/read/28279317/outcomes-after-paravalvular-leak-closure-transcatheter-versus-surgical-approaches
#8
John A Wells, Jose F Condado, Norihiko Kamioka, Andy Dong, Andrew Ritter, Stamatios Lerakis, Stephen Clements, James Stewart, Bradley Leshnower, Robert Guyton, Jessica Forcillo, Ateet Patel, Vinod H Thourani, Peter C Block, Vasilis Babaliaros
OBJECTIVES: The aim of this study was to compare outcomes of transcatheter intervention (TI) versus surgical intervention (SI) for paravalvular leak (PVL). BACKGROUND: Data comparing the treatment of PVL with TI and SI are limited. METHODS: A retrospective cohort study was conducted comparing baseline characteristics, procedural details, and 1-year survival in consecutive patients who underwent TI or SI for moderate or greater PVL from 2007 to 2016...
March 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28275460/reactivation-of-hiv-1-proviruses-in-immune-compromised-mice-engrafted-with-human-voa-negative-cd4-t-cells
#9
EDITORIAL
Zhe Yuan, Guobin Kang, Wuxun Lu, Qingsheng Li
BACKGROUND: HIV-1 infection remains incurable on antiretroviral therapy (ART) due to virus latency. To date, enhanced co-culture assays, including viral outgrowth assays (VOA), are commonly used to measure HIV-1 latent reservoirs and evaluate latency-reversing agents (LRAs). However, VOA can only reactivate a small fraction of intact proviruses. METHODS: To explore the utility of NOD scid gamma (NSG) mice as an in vivo model to reactivate HIV-1 proviruses from VOA-negative CD4+ T cells, resting CD4+ T cells from an HIV-1 latently infected individual were isolated and the human CD4+ T cells corresponding to VOA-positive and VOA-negative CD4+ T cells were engrafted into NSG mice...
January 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28267444/a-multicenter-prospective-study-of-neonatal-outcomes-at-less-than-32-weeks-associated-with-indications-for-maternal-admission-and-delivery
#10
Thomas J Garite, C Andrew Combs, Kimberly Maurel, Anita Das, Kevin Huls, Richard Porreco, Dale Reisner, George Lu, Melissa Bush, Bruce Morris, April Bleich
BACKGROUND: Counseling for patients with impending premature delivery has been traditionally based primarily on the projected gestational age at delivery. There are limited data regarding how the indications for the preterm birth affect the neonatal outcome and whether this issue should be taken into account in decisions regarding management and patient counseling. OBJECTIVE: We performed a prospective study of pregnancies resulting in premature delivery at less than 32 weeks to determine the influence of both the Indications for Admission and their associated Indications for Delivery on neonatal mortality and complications of prematurity...
March 3, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28260753/molecular-characterization-of-methicillin-resistance-staphylococcus-aureus-mrsa-from-different-tertiary-care-hospitals-in-bangladesh
#11
S Roy, T K Barman, M A Hossain, S K Paul, N Haque, S Ahmed, S A Nasreen, M S Hossain, S R Sarkar, N Kubayashi, N Laskar
Infections caused by Staphylococcus aureus were treated by methicillin, but about 95% of S. aureus has been resistance to methicillin, both in the community and hospitals and are increasing day by day. MRSA produces altered penicillin binding protein, PBP2a, due to the expression of mecA gene. Some strains of both the MRSA and MSSA carry PVL gene. This cross sectional observational study was conducted to detect the molecular-characterization of methicillin resistant Staphylococcus aureus (MRSA) and carried out in the Department of Microbiology, Mymensingh Medical College from July 2014 to December 2015...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28259072/a-rare-case-of-acute-osteomyelitis-due-to-panton-valentine-leukocidin-positive-community-acquired-methicillin-resistant-staphylococcus-aureus-in-a-young-healthy-adult
#12
Toshiyuki Takemori, Osamu Nakamura, Yoshiki Yamagami, Hideki Nishimura, Teruya Kawamoto, Toshihiro Akisue, Tetsuji Yamamoto
INTRODUCTION: Most community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections affect skin or soft tissues, while invasive and life-threatening illnesses including osteomyelitis are less common. CA-MRSA infections occur especially in the pediatric age group, while the occurrence of CA-MRSA osteomyelitis in adults is uncommonly reported. PRESENTATION OF CASES: A rare case of acute osteomyelitis of the femur caused by Panton-Valentine leukocidin (PVL)-positive CA-MRSA in a 37-year-old man in good health is presented...
February 17, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28252206/analysis-of-htlv-1-proviral-load-pvl-and-antibody-detected-with-various-kinds-of-tests-in-japanese-blood-donors-to-understand-the-relationship-between-pvl-and-antibody-level-and-to-gain-insights-towards-better-antibody-testing
#13
Chieko Matsumoto, Yasuko Sagara, Rieko Sobata, Yukiko Inoue, Maiko Morita, Shigeharu Uchida, Hiroyuki Kiyokawa, Masahiro Satake, Kenji Tadokoro
Adult T-cell leukemia/lymphoma (ATL) occurs in approximately 5% of individuals infected with human T-cell leukemia virus type 1 (HTLV-1). A high proviral load (PVL; more than 4 copies per 100 peripheral blood mononuclear cells (PBMCs) or 1.6 copies per 100 blood leukocytes) and being male are risk factors for ATL development. Whether anti-HTLV-1 antibody level is related to such risk is unknown. Here, PVL and antibody levels were examined using real-time PCR and other tests in 600 HTLV-1 positive screened Japanese blood donors to understand the relationship between PVL and antibody level in asymptomatic carriers and to gain insights towards better antibody testing for HTLV-1 infection...
March 2, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28251179/fluorocycline-tp-271-is-potent-against-complicated-community-acquired-bacterial-pneumonia-pathogens
#14
Trudy H Grossman, Corey Fyfe, William O'Brien, Meredith Hackel, Mary Beth Minyard, Ken B Waites, Jacques Dubois, Timothy M Murphy, Andrew M Slee, William J Weiss, Joyce A Sutcliffe
TP-271 is a novel, fully synthetic fluorocycline antibiotic in clinical development for the treatment of respiratory infections caused by susceptible and multidrug-resistant pathogens. TP-271 was active in MIC assays against key community respiratory Gram-positive and Gram-negative pathogens, including Streptococcus pneumoniae (MIC90 = 0.03 µg/ml), methicillin-sensitive Staphylococcus aureus (MSSA; MIC90 = 0.25 µg/ml), methicillin-resistant S. aureus (MRSA; MIC90 = 0.12 µg/ml), Streptococcus pyogenes (MIC90 = 0...
January 2017: MSphere
https://www.readbyqxmd.com/read/28250256/antimicrobial-resistance-and-molecular-characteristics-of-methicillin-resistant-staphylococcus-aureus-isolates-from-child-patients-of-high-risk-wards-in-shenzhen-china
#15
Yang Qin, Feiqiu Wen, Yuejie Zheng, Ruizhen Zhao, Qinghua Hu, Renli Zhang
Methicillin-resistant Staphylococcus aureus (MRSA) causes high rates of mortality and a substantial burden to health systems worldwide. Here, we investigated the antimicrobial susceptibility and molecular characteristics of MRSA isolated from children treated at Shenzhen Children's Hospital. 140 MRSA strains were characterized by antimicrobial susceptibility testing. We further performed spa typing, multilocus sequence typing (MLST), staphylococcal cassette chromosome mec (SCCmec), pvl gene and pulsed-field gel electrophoresis (PFGE)...
February 28, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28248407/hemodynamic-changes-after-transcatheter-aortic-valve-implantation-during-sequential-follow-ups-in-patients-with-bicuspid-aortic-valve-compared-with-tricuspid-aortic-valve
#16
Tian-Yuan Xiong, Ming-Xia Zheng, Xin Wei, Yi-Jian Li, Yan-Biao Liao, Zhen-Gang Zhao, Yuan-Ning Xu, Hong Tang, Yuan Feng, Mao Chen
BACKGROUND: To investigate the individual sequential hemodynamic changes after transcatheter aortic valve implantation (TAVI), especially for patients with bicuspid aortic valve (BAV), in comparison with tricuspid aortic valve (TAV). METHODS: The study population comprised 85 patients with severe aortic stenosis who underwent TAVI for BAV (n = 49) or TAV (n = 36) with at least two serial echocardiographic follow-ups. Doppler echocardiography was scheduled to be performed at discharge and 1, 3, 6 months and 1 year after the procedure...
March 1, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28223977/staphylococcal-aureus-enterotoxin-c-and-enterotoxin-like-l-associated-with-post-partum-mastitis
#17
Kristina T Franck, Heidi Gumpert, Bente Olesen, Anders R Larsen, Andreas Petersen, Jette Bangsborg, Per Albertsen, Henrik Westh, Mette D Bartels
Denmark is a low prevalence country with regard to methicillin resistant Staphylococcus aureus (MRSA). In 2008 and 2014, two neonatal wards in the Copenhagen area experienced outbreaks with a typical community acquired MRSA belonging to the same spa type and sequence type (t015:ST45) and both were PVL and ACME negative. In outbreak 1, the isolates harbored SCCmec IVa and in outbreak 2 SCCmec V. The clinical presentation differed between the two outbreaks, as none of five MRSA positive mothers in outbreak 1 had mastitis vs...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28210352/risk-of-skin-and-soft-tissue-infections-among-children-found-to-be-staphylococcus-aureus-mrsa-usa300-carriers
#18
Lilly Cheng Immergluck, Shabnam Jain, Susan M Ray, Robert Mayberry, Sarah Satola, Trisha Chan Parker, Keming Yuan, Anaam Mohammed, Robert C Jerris
INTRODUCTION: The purpose of this study was to examine community-associated methicillin resistant Staphylococcus aureus (CA-MRSA) carriage and infections and determine risk factors associated specifically with MRSA USA300. METHODS: We conducted a case control study in a pediatric emergency department. Nasal and axillary swabs were collected, and participants were interviewed for risk factors. The primary outcome was the proportion of S. aureus carriers among those presenting with and without a skin and soft tissue infection (SSTI)...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28209261/the-feasibility-of-transcatheter-aortic-valve-implantation-using-the-edwards-sapien-3-for-patients-with-severe-bicuspid-aortic-stenosis
#19
Takahide Arai, Thierry Lefèvre, Thomas Hovasse, Marie-Claude Morice, Mauro Romano, Hakim Benamer, Philippe Garot, Kentaro Hayashida, Erik Bouvier, Bernard Chevalier
BACKGROUND: There are currently only limited data focusing on transcatheter aortic valve implantation (TAVI) for bicuspid aortic valves (BAV) patients using the Edwards SAPIEN (Irvine, CA, USA) 3 (S3) valve. The aim of this study was to evaluate the feasibility and efficacy of TAVI using the S3 in patients with BAV. METHODS: A total of 153 TAVI cases performed with the S3 were included. BAV was detected by multidetector computed tomography (MDCT) in 10 (7%) patients...
February 10, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28206670/altered-expression-of-cxcr3-and-ccr6-and-their-ligands-in-htlv-1-carriers-and-ham-tsp-patients
#20
Houshang Rafatpanah, Mehdi Felegari, Mahmoud Reza Azarpazhooh, Rosita Vakili, Taraneh Rajaei, Ian Hampson, Golmahossein Hassanshahi, Narges Valizadeh, Sina Gerayli, Farajifard Hamid, Shadi Zamanian, Farzad MollaHosseini, Seyed Abdolrahim Rezaee
Recruitment of leukocytes by chemokines and chemokine receptors to CNS plays a crucial role in the induction of inflammatory response in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). In the present study, chemokine and chemokine receptors involved in trafficking of lymphocytes to the CNS were measured in HAM/TSP patients, HTLV-1 asymptomatic carriers (ACs), and healthy controls. The PVL, CCR6, and CXCR3 mRNA expression, and CXCL9 and CXCL10 protein levels were measured in all subjects...
February 16, 2017: Journal of Medical Virology
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