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https://www.readbyqxmd.com/read/28814035/decoding-of-individual-finger-movements-from-surface-emg-signals-using-vector-autoregressive-hierarchical-hidden-markov-models-varhhmm
#1
Nebojsa Malesevic, Dimitrije Markovic, Gunter Kanitz, Marco Controzzi, Christian Cipriani, Christian Antfolk
In this paper we present a novel method for predicting individual fingers movements from surface electromyography (EMG). The method is intended for real-time dexterous control of a multifunctional prosthetic hand device. The EMG data was recorded using 16 single-ended channels positioned on the forearm of healthy participants. Synchronously with the EMG recording, the subjects performed consecutive finger movements based on the visual cues. Our algorithm could be described in following steps: extracting mean average value (MAV) of the EMG to be used as the feature for classification, piece-wise linear modeling of EMG feature dynamics, implementation of hierarchical hidden Markov models (HHMM) to capture transitions between linear models, and implementation of Bayesian inference as the classifier...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28814031/evaluation-of-walking-smoothness-using-wearable-robotic-system-curara%C3%A2-for-spinocerebellar-degeneration-patients
#2
Atsushi Tsukahara, Kunihiro Yoshida, Akira Matsushima, Kumiko Ajima, Chika Kuroda, Noriaki Mizukami, Minoru Hashimoto
This paper aimed to verify the effectiveness of the wearable robotic system "curara" for patients with spinocerebellar degeneration (SCD) by evaluating walking smoothness. The curara system supports the wearer's gait using a synchronization control method that uses a neural oscillator based on a central pattern generator network. The system reflects the motional intention by adjusting the synchronization gains. This modifies the degree of interactive coordinated motion between the curara and the wearer. As a feasibility study, we evaluated the waking smoothness of 10 patients with SCD using three gain condition settings...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28814020/piecewise-and-unified-phase-variables-in-the-control-of-a-powered-prosthetic-leg
#3
Dario J Villarreal, David Quintero, Robert D Gregg
Many control methods have been proposed for powered prosthetic legs, ranging from finite state machines that switch between discrete phases of gait to unified controllers that have a continuous sense of phase. In particular, recent work has shown that a mechanical phase variable can parameterize the entire gait cycle for controlling a prosthetic leg during steady rhythmic locomotion. However, the unified approach does not provide voluntary control over non-rhythmic motions like stepping forward and back. In this paper we present a phasing algorithm that uses the amputee's hip angle to control both rhythmic and non-rhythmic motion through two modes: 1) a piecewise (PW) function that provides users voluntary control over stance and swing in a piecewise manner, and 2) a unified function that continuously synchronizes the motion of the prosthetic leg with the amputee user at different walking speeds...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813899/the-effects-of-auditory-and-visual-cues-on-timing-synchronicity-for-robotic-rehabilitation
#4
Brittney A English, Ayanna M Howard
In this paper, we explore how the integration of auditory and visual cues can help teach the timing of motor skills for the purpose of motor function rehabilitation. We conducted a study using Amazon's Mechanical Turk in which 106 participants played a virtual therapy game requiring wrist movements. To validate that our results would translate to trends that could also be observed during robotic rehabilitation sessions, we recreated this experiment with 11 participants using a robotic wrist rehabilitation system as means to control the therapy game...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813827/biomechanical-effects-of-robot-assisted-walking-on-knee-joint-kinematics-and-muscle-activation-pattern
#5
Pavithra Thangavel, S Vidhya, Junhua Li, Effie Chew, Anastasios Bezerianos, Haoyong Yu
Since manual rehabilitation therapy can be taxing for both the patient and the physiotherapist, a gait rehabilitation robot has been built to reduce the physical strain and increase the efficacy of the rehabilitation therapy. The prototype of the gait rehabilitation robot is designed to provide assistance while walking for patients with abnormal gait pattern and it can also be used for rehabilitation therapy to restore an individual's normal gait pattern by aiding motor recovery. The Gait Rehabilitation Robot uses gait event based synchronization, which enables the exoskeleton to provide synchronous assistance during walking that aims to reduce the lower-limb muscle activation...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813412/the-primed-snare-complexin-synaptotagmin-complex-for-neuronal-exocytosis
#6
Qiangjun Zhou, Peng Zhou, Austin L Wang, Dick Wu, Minglei Zhao, Thomas C Südhof, Axel T Brunger
Synaptotagmin, complexin, and neuronal SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) proteins mediate evoked synchronous neurotransmitter release, but the molecular mechanisms mediating the cooperation between these molecules remain unclear. Here we determine crystal structures of the primed pre-fusion SNARE-complexin-synaptotagmin-1 complex. These structures reveal an unexpected tripartite interface between synaptotagmin-1 and both the SNARE complex and complexin. Simultaneously, a second synaptotagmin-1 molecule interacts with the other side of the SNARE complex via the previously identified primary interface...
August 16, 2017: Nature
https://www.readbyqxmd.com/read/28813229/cortical-networks-for-correcting-errors-in-sensorimotor-synchronization-depend-on-the-direction-of-asynchrony
#7
K J Jantzen, Benjamin R Ratcliff, McNeel G Jantzen
Recent work provides clues that different cortical mechanisms may be employed when correcting for errors in sensorimotor synchronization that increase tap-tone asynchrony compared with those that decrease it. The authors tested this hypothesis by recording 64-channel electroencephalography while participants synchronized with an auditory metronome. We systematically introduced positive and negative phase-shift perturbations that were either liminal (10%) and subliminal (3%). We used a distributed source modeling approach to evaluate oscillatory activity and connectivity of discrete cortical sources...
August 16, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28812672/rapid-and-direct-recoveries-of-predators-and-prey-through-synchronized-ecosystem-management
#8
Jameal F Samhouri, Adrian C Stier, Shannon M Hennessey, Mark Novak, Benjamin S Halpern, Phillip S Levin
One of the twenty-first century's greatest environmental challenges is to recover and restore species, habitats and ecosystems. The decision about how to initiate restoration is best-informed by an understanding of the linkages between ecosystem components and, given these linkages, an appreciation of the consequences of choosing to recover one ecosystem component before another. However, it remains difficult to predict how the sequence of species' recoveries within food webs influences the speed and trajectory of restoration, and what that means for human well-being...
March 1, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28811821/prognostic-factors-affecting-long-term-survival-after-resection-for-noncolorectal-nonneuroendocrine-and-nonsarcoma-liver-metastases
#9
Fabio Uggeri, Enrico Pinotti, Marta Sandini, Luca Nespoli, Luca Gianotti, Fabrizio Romano
AIM: To evaluate feasibility and long-term outcome after hepatic resection for noncolorectal, nonneuroendocrine, and nonsarcoma (NCNNNS) liver metastases in a single center. METHODS: We retrospectively reviewed our experience on patients who underwent surgery for NCNNNS liver metastases from 1995 to 2015. Patient baseline characteristics, tumor features, treatment options, and postoperative outcome were retrieved. RESULTS: We included 47 patients...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28811195/epileptic-interictal-discharges-are-more-frequent-during-nrem-slow-wave-downstates
#10
Péter Przemyslaw Ujma, Péter Halász, Anna Kelemen, Dániel Fabó, Loránd Erőss
Epileptiform activity in various but not all epilepsy and recording types and cerebral areas is more frequent in NREM sleep, and especially during sleep periods with high-amplitude EEG slow waves. Slow waves synchronize high-frequency oscillations: physiological activity from the theta through the gamma band usually appears during scalp-positive upstates while epileptiform activity occurs at transitory phases and the scalp-negative downstate. It has been proposed that interictal discharges (IIDs) are facilitated by the high degree of neuronal firing synchrony during slow wave transitory and downstates...
August 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28810958/multispecialty-synchronous-telehealth-utilization-and-patient-satisfaction-within-regional-health-command-europe-a-readiness-and-recapture-system-for-health
#11
Kirk H Waibel, Steven M Cain, Todd E Hall, Ronald S Keen
BACKGROUND: Telehealth implementation within the Military Healthcare System continues to advance toward the goal of a mature regional health platform; however, specialty-specific usage or patient satisfaction regarding synchronous or "real-time" telehealth at the regional military hospital level has not been described. METHODS: A retrospective review of synchronous telehealth encounters and patient satisfaction surveys from Landstuhl Regional Medical Center (LRMC) specialty clinics engaging in synchronous telehealth to regional Army Health Clinics (AHCs) during 2015 was conducted...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810889/dehydroepiandrosterone-sulfate-and-dehydroepiandrosterone-sulfate-cortisol-ratio-in-cirrhotic-patients-with-septic-shock-another-sign-of-hepatoadrenal-syndrome
#12
Ming-Hung Tsai, Hui-Chun Huang, Yun-Shing Peng, Yung-Chang Chen, Ya-Chung Tian, Chih-Wei Yang, Jau-Min Lien, Ji-Tseng Fang, Cheng-Shyong Wu, Sen-Yung Hsieh, Fa-Yauh Lee
BACKGROUND: Cirrhotic patients are susceptible to sepsis and critical illness-related corticosteroid insufficiency (CIRCI). Dehydroepiandrosterone sulfate (DHEAS) is a corticotropin-dependent adrenal androgen, which has immunostimulating and antiglucocorticoid effects. Considering the synchronized synthesis of cortisol and DHEAS and their opposing effects to each other, investigators have proposed measuring these two hormones as a ratio. Severe sepsis has been associated with low DHEAS, especially relative to high cortisol...
August 15, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28810724/sympathetic-nerve-traffic-and-blood-pressure-changes-after-bilateral-renal-denervation-in-resistant-hypertension-a-time-integrated-analysis
#13
Gino Seravalle, Graziella D'Arrigo, Giovanni Tripepi, Francesca Mallamaci, Gianmaria Brambilla, Giuseppe Mancia, Guido Grassi, Carmine Zoccali
Background: Renal denervation reduces blood pressure (BP) and sympathetic drive in experimental animal models, but the effect of this intervention on sympathetic activity in patients with treatment-resistant hypertension is still unclear. Methods: In an incident series of 29 patients with treatment-resistant hypertension, we performed serial measurements (n = 123) of muscle sympathetic nerve activity (MSNA, microneurography) and standardized BP measurements. Data were analysed by mixed linear modelling (MLM) and by regression analysis of time-integrated changes of both MSNA and synchronous, standardized (in-lab) BP measurements...
August 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28810213/the-effect-of-circulating-progesterone-on-magnitude-of-the-gnrh-induced-lh-surge-are-there-any-differences-between-bos-indicus-and-bos-taurus-heifers
#14
E O S Batista, T A Del Valle, M D D V Ortolan, F P Rennó, G P Nogueira, A H Souza, P S Baruselli
This study evaluated the effects of differing circulating progesterone (P4) levels on the luteinizing hormone (LH) surge profile following treatment with gonadotropin releasing hormone (GnRH) in B. indicus (Nelore, n = 13) and B. taurus (Holstein, n = 16) heifers. All heifers were synchronized with a hormonal protocol to induce either a Low or High circulating P4 environment at the time of GnRH treatment. Heifers were randomly assigned to a 2 × 2 factorial design composed by two genetic groups (B. indicus and B...
August 5, 2017: Theriogenology
https://www.readbyqxmd.com/read/28809974/in-situ-generation-of-electrochemiluminescent-dna-nanoflowers-as-a-signal-tag-for-mucin-1-detection-based-on-a-strategy-of-target-and-mimic-target-synchronous-cycling-amplification
#15
Sheng-Kai Li, An-Yi Chen, Xiao-Xue Niu, Zhi-Ting Liu, Min Du, Ya-Qin Chai, Ruo Yuan, Ying Zhuo
A sensitive electrochemiluminescent (ECL) aptasensor consisting of a novel ECL signal tag of DNA nanoflowers (DNA NFs) and a highly efficient target conversion strategy for the MUC1 assay was developed, which not only increased the stability for luminophore loading, but also greatly improved the detection sensitivity.
August 15, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28809943/genetic-evidence-for-subspecies-differentiation-of-the-himalayan-marmot-marmota-himalayana-in-the-qinghai-tibet-plateau
#16
Jingyan Yan, Hongjian Chen, Gonghua Lin, Qian Li, Jiarui Chen, Wen Qin, Jianping Su, Tongzuo Zhang
The primary host of plague in the Qinghai-Tibet Plateau (QTP), China, is Marmota himalayana, which plays an essential role in the maintenance, transmission, and prevalence of plague. To achieve a more clear insight into the differentiation of M. himalayana, complete cytochrome b (cyt b) gene and 11 microsatellite loci were analyzed for a total of 423 individuals from 43 localities in the northeast of the QTP. Phylogenetic analyses with maximum likelihood and Bayesian inference methods showed that all derived haplotypes diverged into two primary well-supported monophyletic lineages, I and II, which corresponded to the referential sequences of two recognized subspecies, M...
2017: PloS One
https://www.readbyqxmd.com/read/28809793/the-degree-of-temporal-synchronization-of-the-pulse-oscillations-from-a-gain-switched-multimode-semiconductor-laser
#17
Kenji Wada, Naoaki Kitagawa, Tetsuya Matsuyama
Langevin noise leads to inhibition of the temporal synchronization of the pulse oscillations from a gain-switched multimode semiconductor laser, resulting in the power reduction in optical beat detection. In this paper, the degree of the temporal synchronization of the pulse oscillations was examined by numerically estimating the output energy in THz time-domain spectroscopy (THz-TDS) using multimode semiconductor laser rate equations that include Langevin noise. The degree was estimated to be 95.5% from the ratio of the averaged THz-TDS output energy for the case where Langevin noise was included to that for when Langevin noise was excluded...
August 15, 2017: Materials
https://www.readbyqxmd.com/read/28809706/cluster-synchronization-of-coupled-genetic-regulatory-networks-with-delays-via-aperiodically-adaptive-intermittent-control
#18
Zhi-Hong Guan, Dandan Yue, Bin Hu, Tao Li, Feng Liu
In this paper, we study the cluster synchronization of coupled genetic regulatory networks with time-varying delays via aperiodically adaptive intermittent control on some nodes. The network is intermittently coupled and the intra-cluster coupling strength is adaptively adjusted. The graph of the coupling topology of each cluster is only required to have a directed spanning tree. Two cases of delays are considered. In the first case, by using the switching Lyapunov-based function and Razumikhintype technique, the cluster synchronization criterion is presented which indicates that the cluster synchronization is realized via the aperiodically adaptive intermittent control...
August 10, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28809158/germ-cell-connectivity-enhances-cell-death-in-response-to-dna-damage-in-the-drosophila-testis
#19
Kevin L Lu, Yukiko M Yamashita
Two broadly known characteristics of germ cells in many organisms are their development as a 'cyst' of interconnected cells and their high sensitivity to DNA damage. Here we provide evidence that in the Drosophila testis, connectivity serves as a mechanism that confers to spermatogonia a high sensitivity to DNA damage. We show that all spermatogonia within a cyst die synchronously even when only a subset of them exhibit detectable DNA damage. Mutants of the fusome, an organelle that is known to facilitate intracyst communication, compromise synchronous spermatogonial death and reduces overall germ cell death...
August 15, 2017: ELife
https://www.readbyqxmd.com/read/28808559/reproductive-cycles-in-tropical-intertidal-gastropods-are-timed-around-tidal-amplitude-cycles
#20
Rachel Collin, Kecia Kerr, Gina Contolini, Isis Ochoa
Reproduction in iteroparous marine organisms is often timed with abiotic cycles and may follow lunar, tidal amplitude, or daily cycles. Among intertidal marine invertebrates, decapods are well known to time larval release to coincide with large amplitude nighttime tides, which minimizes the risk of predation. Such bimonthly cycles have been reported for few other intertidal invertebrates. We documented the reproduction of 6 gastropod species from Panama to determine whether they demonstrate reproductive cycles, whether these cycles follow a 2-week cycle, and whether cycles are timed so that larval release occurs during large amplitude tides...
August 2017: Ecology and Evolution
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