keyword
MENU ▼
Read by QxMD icon Read
search

Envenomation

keyword
https://www.readbyqxmd.com/read/28920799/presumptive-pit-viper-envenomation-in-psittacines-in-a-brazilian-zoo
#1
Mathias Dislich, Peter Wohlsein, Anna Sophie Croukamp, Ulrich Neumann
Snake bites represent a serious public health risk in many regions of the globe, especially in tropical areas. Clinical signs and postmortem changes are well described in human and other mammalian species. However, detailed case reports about venomous snake attacks in avian species are limited. This report describes presumptive fatal envenomations in three psittacines caused by pit vipers in a Brazilian zoo. In one case, a Brazilian lancehead (Bothrops moojeni) was captured in the aviary. In all three cases the dermis around the suspected snake bite area exhibited hemorrhages and edema...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28918605/food-or-threat-wild-capuchin-monkeys-sapajus-libidinosus-as-both-predators-and-prey-of-snakes
#2
Tiago Falótico, Michele P Verderane, Olívia Mendonça-Furtado, Noemi Spagnoletti, Eduardo B Ottoni, Elisabetta Visalberghi, Patrícia Izar
Snakes present a hazard to primates, both as active predators and by defensive envenomation. This risk might have been a selective pressure on the evolution of primate visual and cognitive systems, leading to several behavioral traits present in human and non-human primates, such as the ability to quickly learn to fear snakes. Primates seldom prey on snakes, and humans are one of the few primate species that do. We report here another case, the wild capuchin monkey (Sapajus libidinosus), which preys on snakes...
September 16, 2017: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/28918200/profiling-the-short-linear-non-disulfide-bond-containing-peptidome-from-the-venom-of-the-scorpion-tityus-obscurus
#3
Nathalia Baptista Dias, Bibiana Monson de Souza, Fernando Kamimura Cocchi, Hipócrates M Chalkidis, Valquíria Abrão Coronado Dorce, Mario Sergio Palma
Many scorpion accidents occur in the Brazilian Amazonian region and are frequently caused by Tityus obscurus. Approximately 5% of the crude venom of this species is composed of short linear, non-disulfide-bridged peptides, which have not been intensively investigated. As a consequence, only a few of these peptides have been structurally and functionally characterized to date. In the present paper, the peptide fraction of the venom was subjected to peptide profiling using an LCMS-IT-TOF/MS and MS(n) system. The analysis detected 320 non-disulfide bond-containing peptides (NDBPs), of which twenty-seven had their sequences assigned; among them, thirteen peptides were characterized, constituting novel toxins in T...
September 13, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28905944/snakebite-envenoming
#4
REVIEW
José María Gutiérrez, Juan J Calvete, Abdulrazaq G Habib, Robert A Harrison, David J Williams, David A Warrell
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty. Snake venoms are complex mixtures of proteins that exert a wide range of toxic actions. The high variability in snake venom composition is responsible for the various clinical manifestations in envenomings, ranging from local tissue damage to potentially life-threatening systemic effects...
September 14, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28905943/snakebite-envenoming
#5
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
September 14, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28905655/inverted-takotsubo-syndrome-in-androctonus-australis-scorpion-envenomation
#6
Fekri Abroug, Islem Ouanes, Mezri Maatouk, Mondher Golli, Lamia Ouanes-Besbes
CONTEXT: The nature of scorpion-related cardiomyopathy is still a matter of debate where specific toxin-induced cardiomyopathy, ischemic, or catecholaminergic cardiomyopathy is advocated as well. We report two cases of Takotsubo syndrome following envenomation by Androctonus australis, bringing new evidence for the fundamental role of catecholamines in the pathogenesis of this cardiomyopathy. Case 1: A woman aged 36 presented with pulmonary edema and shock following scorpion envenomation...
September 14, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28904556/medicinal-plants-for-the-treatment-of-local-tissue-damage-induced-by-snake-venoms-an-overview-from-traditional-use-to-pharmacological-evidence
#7
REVIEW
Juliana Félix-Silva, Arnóbio Antônio Silva-Junior, Silvana Maria Zucolotto, Matheus de Freitas Fernandes-Pedrosa
Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects. Thus, the search for complementary alternatives for snakebite treatment is relevant. There are several reports of the popular use of medicinal plants against snakebites worldwide. In recent years, many studies have been published giving pharmacological evidence of benefits of several vegetal species against local effects induced by a broad range of snake venoms, including inhibitory potential against hyaluronidase, phospholipase, proteolytic, hemorrhagic, myotoxic, and edematogenic activities...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28889321/effects-of-purified-human-fibrinogen-modified-with-carbon-monoxide-and-iron-on-coagulation-in-rabbits-injected-with-crotalus-atrox-venom
#8
Vance G Nielsen
While snake venom derived enzymes, such as the thrombin-like activity possessing ancrod, have been used to treat thrombotic disease by defibrinogenating patients, the therapeutic potential of fibrinogenolytic snake venom enzymes, such as those derived from Crotalus atrox, have not been fully explored. However, one of the potential risks of administering fibrinogenolytic enzymes to effect defibrinogenation is hemorrhage secondary to hypofibrinogenemia. The present investigation sought to determine if human fibrinogen modified with carbon monoxide (CO) and iron (Fe) could resist degradation by C...
September 9, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28887121/discovery-of-human-scfvs-that-cross-neutralize-the-toxic-effects-of-b-jararacussu-and-c-d-terrificus-venoms
#9
Luciano C Silva, Manuela B Pucca, Gabriela Pessenda, Lucas B Campos, Edson Z Martinez, Felipe A Cerni, José E Barbosa
Accidents involving venomous snakes are a public health problem worldwide, causing a large number of deaths per year. In Brazil, the majority of accidents are caused by the Bothrops and Crotalus genera, which are responsible for approximately 80% of severe envenoming cases. The cross-neutralization of snake venoms by antibodies is an important issue for development of more effective treatments. Our group has previously reported the construction of human monoclonal antibody fragments towards Bothrops jararacussu and Crotalus durissus terrificus' venoms...
September 5, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28885114/clinical-predictors-of-tissue-necrosis-following-rattlesnake-envenomation
#10
C William Heise, Anne-Michelle Ruha, Angela Padilla-Jones, Carrie Truitt Hayek, Richard D Gerkin
BACKGROUND: Rattlesnake envenomation (RSE) causes edema, hemotoxicity and tissue necrosis. Necrosis may result in permanent disability. OBJECTIVE: To study patient-related factors associated with tissue necrosis after Crotalus envenomation. METHODS: Prospective cohort study of patients admitted to the Medical Toxicology service with diagnosis of RSE between April 2011 and November 2014. Inclusion criteria were age ≥18 years and upper extremity (UE) envenomation site...
September 8, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28884031/a-case-of-lionfish-envenomation-presenting-to-an-inland-emergency-department
#11
Rachel F Schult, Nicole M Acquisto, Crystal K Stair, Timothy J Wiegand
Lionfish envenomation can cause erythema, edema, necrosis, and severe pain at the exposed site. Treatment often includes supportive wound care, pain management, and hot water immersion. We report a case of lionfish exposure presenting to an inland emergency department treated successfully with these measures.
2017: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/28878435/assessment-of-knowledge-about-snakebite-management-amongst-healthcare-providers-in-the-provincial-and-two-district-hospitals-in-savannakhet-province-lao-pdr
#12
Vongphoumy Inthanomchanh, Joshua A Reyer, Joerg Blessmen, Ketkesone Phrasisombath, Eiko Yamamoto, Nobuyuki Hamajima
Snakebite is a neglected condition and a common public health problem in Lao People's Democratic Republic (Lao PDR), with a high incidence of up to 1,105 cases per 100,000 persons per year. Snakebite patients with systemic envenoming do not receive effective treatment at local health facilities. Healthcare providers have only limited knowledge in assessing and providing the correct treatment for venomous snakebites. A cross-sectional study was conducted among 119 healthcare providers in Savannakhet Province, Lao PDR, with respect to their socio-demographic characteristics, knowledge of snake identification, and management of snakebite...
August 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28877511/severe-neurotoxicity-requiring-mechanical-ventilation-in-a-dog-envenomed-by-a-red-bellied-black-snake-pseudechis-porphyriacus-and-successful-treatment-with-an-experimental-bivalent-whole-equine-igg-antivenom
#13
A M Padula, E M Leister
Snakebite in dogs from Pseudechis porphyriacus (red-bellied black snake; RBBS) is a common envenomation treated by veterinarians in Australia where this snake occurs. This case report describes the successful treatment of a clinically severe RBBS envenomation in a dog with an experimental bivalent equine whole IgG antivenom and mechanical ventilation, following its presentation in a cyanotic state. The cause of the cyanosis and respiratory distress was considered due to paralysis from neurotoxins in RBBS venom...
September 4, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28873251/imported-fire-ant-envenomation-a-clinicopathologic-study-of-a-recognizable-form-of-arthropod-assault-reaction
#14
Gabriel Villada, Farhaan Hafeez, Jose Ollague, Carlos H Nousari, George W Elgart
BACKGROUND: Skin reactions to the sting of the imported fire ant have characteristic clinicopathological features. METHODS: One case of experimental envenomation was prospectively followed during 48 hours, with biopsies. In addition, six cases from our laboratory were retrospectively evaluated histopathologically for the following features: spongiosis, exocytosis (and type of cells), pustule formation, erosion/ulceration, epidermal necrosis, scale/crust, papillary dermal edema, inflammatory dermal infiltrate (cell type, density, depth, distribution, shape), red blood cell extravasation, vasculopathy, vasculitis...
September 5, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28871821/centruroides-sculpturatus-envenomation-in-three-adult-patients-requiring-treatment-with-antivenom
#15
Nicholas B Hurst, Demis N Lipe, Stephen R Karpen, Asad E Patanwala, Ann M Taylor, Keith J Boesen, F Mazda Shirazi
CONTEXT: Envenomation by Centruroides sculpturatus can manifest with cranial nerve dysfunction and neuromuscular hyperactivity. While these symptoms are most commonly seen in young children, they may also be seen in adults. CASE DETAILS: Three cases of adult patients are presented with grades III & IV scorpion envenomation. They reported symptoms including disconjugate, roving eye movements, and motor involvement. Also reported were hyposmia, difficulty with fine motor movements, and dysgeusia...
September 5, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28866287/dangerous-arachnids-fake-news-or-reality
#16
REVIEW
Tobias J Hauke, Volker Herzig
The public perception of spiders and scorpions is skewed towards the potential harm they can inflict in humans, despite recent scientific evidence that arachnid venom components might be useful as bioinsecticides or even human therapeutics. Nevertheless, arachnids are becoming more popular as pets in Europe, America and Asia, raising the question for regulatory agencies in these regions as to whether they need to take measurements to protect their citizens. In order to decide upon the necessary regulatory steps, they first need to determine which arachnids are actually dangerous to humans...
September 1, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28855813/saudi-medicinal-plants-for-the-treatment-of-scorpion-sting-envenomation
#17
REVIEW
Abdulrahman Al-Asmari, Rajamohamed Abbas Manthiri, Nasreddien Abdo, Fawzi Abdullah Al-Duaiji, Haseeb Ahmad Khan
Scorpion sting envenoming poses major public health problems. The treatment modalities include antivenoms, chemical antidotes and phytotherapy, with varying degrees of effectiveness and side effects. In this investigation, we reviewed the use of Saudi medicinal plants for the treatment of scorpion sting patients. The relevant literature was collected using the online search engines including Science Direct, Google and PubMed with the help of specific keywords. We also used the printed and online resources at our institutional library to gather the relevant information on the use of medicinal plants for the treatment of scorpion sting patients...
September 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28850773/a-synthetic-biology-approach-for-consistent-production-of-plant-made-recombinant-polyclonal-antibodies-against-snake-venom-toxins
#18
J M Julve Parreño, E Huet, A Fernández-Del-Carmen, A Segura, M Venturi, A Gandía, W-S Pan, I Albaladejo, J Forment, D Pla, A Wigdorovitz, J J Calvete, C Gutiérrez, J M Gutiérrez, A Granell, D Orzáez
Antivenoms developed from the plasma of hyper-immunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease. We describe a synthetic biology approach to affordable and cost-effective antivenom production based on plant-made recombinant polyclonal antibodies (termed pluribodies). The strategy takes advantage of virus superinfection exclusion to induce the formation of somatic expression mosaics in agroinfiltrated plants, which enables the expression of complex antibody repertoires in a highly reproducible manner...
August 29, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28847707/updating-knowledge-on-new-medically-important-scorpion-species-in-mexico
#19
Lidia Riaño-Umbarila, Everardo R Rodríguez-Rodríguez, Carlos E Santibañez-López, Leopoldo Güereca, Selene J Uribe-Romero, Ilse V Gómez-Ramírez, Edson N Cárcamo-Noriega, Lourival D Possani, Baltazar Becerril
The increment in the number of scorpion envenoming cases in Mexico is mainly associated to the rapid growth of the urban areas, and consequently, to the invasion of natural habitats of these arachnids. On the other hand, there is a great diversity of scorpion species, so it is indispensable to identify those of medical importance, which we now know are many more than the 7-8 previously reported as dangerous to humans. Because different LD50 values have been reported for the venom of the same species, probably due to variations in the experimental conditions used, in this work we determined the LD50 values for the venoms of 13 different species of scorpions using simple but systematic procedures...
August 25, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28847519/differential-procoagulant-effects-of-saw-scaled-viper-serpentes-viperidae-echis-snake-venoms-on-human-plasma-and-the-narrow-taxonomic-ranges-of-antivenom-efficacies
#20
Aymeric Rogalski, Christoffer Soerensen, Bianca Op den Brouw, Callum Lister, Daniel Dashevsky, Kevin Arbuckle, Alexandra Gloria, Christina N Zdenek, Nicholas R Casewell, José María Gutiérrez, Wolfgang Wüster, Syed A Ali, Paul Masci, Paul Rowley, Nathaniel Frank, Bryan G Fry
Saw-scaled vipers (genus Echis) are one of the leading causes of snakebite morbidity and mortality in parts of Sub-Saharan Africa, the Middle East, and vast regions of Asia, constituting a public health burden exceeding that of almost any other snake genus globally. Venom-induced consumption coagulopathy, owing to the action of potent procoagulant toxins, is one of the most relevant clinical manifestations of envenomings by Echis spp. Clinical experience and prior studies examining a limited range of venoms and restricted antivenoms have demonstrated for some antivenoms an extreme lack of antivenom cross-reactivity between different species of this genus, sometimes resulting in catastrophic treatment failure...
August 25, 2017: Toxicology Letters
keyword
keyword
1550
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"