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Brachial neuropathy

A M Mahon, C MacGilchrist, C McIntosh, T O'Brien
BACKGROUND: Diabetes mellitus, coined the 'Black Death of the Twenty-First Century', is associated with complications, including foot ulceration with potential loss of limb. There is a need for development of new wound therapies through completion of robust clinical trials. AIMS: To profile demographics and wound characteristics of an Irish cohort with diabetes, forecast eligibility for entry to a clinical trial of advanced wound therapeutics, and adjust criteria to optimize eligibility for enrolment...
October 11, 2016: Irish Journal of Medical Science
Byung-Joon Jeon, Hwan Jun Choi, Jin Seok Kang, Min Sung Tak, Eun Soo Park
Diabetes mellitus is a common metabolic disorder. Among various complications, diabetic neuropathy and peripheral vascular disorders are closely associated with diabetic foot ulcers (DFUs). Lower extremity ulcers and amputations are ongoing problems among individuals with diabetes. There are several classification systems for DFUs; however, no prognostic system has to date been accepted as the gold standard or the optimum prediction tool for amputations. A retrospective study was designed. Demographic data and baseline laboratory data were gathered and scored or evaluated using five representative DFU classification systems...
October 10, 2016: International Wound Journal
Oscar H Del Brutto, Robertino M Mera, Nathan R King, Mauricio Zambrano, Lauren J Sullivan
BACKGROUND/OBJECTIVES: Prevalence of diabetes-related foot disorders (DRFD) in rural areas of developing countries is unknown. The burden of these conditions in Atahualpa, a rural Ecuadorian village, were assessed. METHODS: Using a population-based design, Atahualpa residents aged ≥40 years with diabetes mellitus were identified. Ankle brachial index determinations were used to assess presence of peripheral arterial disease, and the Michigan Neuropathy Screening Instrument was used to estimate peripheral neuropathy...
June 2, 2016: Foot
Brett M Morrison
Neuromuscular diseases are a broadly defined group of disorders that all involve injury or dysfunction of peripheral nerves or muscle. The site of injury can be in the cell bodies (i.e., amyotrophic lateral sclerosis [ALS] or sensory ganglionopathies), axons (i.e., axonal peripheral neuropathies or brachial plexopathies), Schwann cells (i.e., chronic inflammatory demyelinating polyradiculoneuropathy), neuromuscular junction (i.e., myasthenia gravis or Lambert-Eaton myasthenic syndrome), muscle (i.e., inflammatory myopathy or muscular dystrophy), or any combination of these sites...
October 2016: Seminars in Neurology
Sui-Whi Jane, Ming-Shyan Lin, Wen-Nan Chiu, Randal D Beaton, Mei-Yen Chen
OBJECTIVES: To explore the prevalence, discomfort, and self-relief behaviours of painful diabetic neuropathy (PDN) among rural community residents with type 2 diabetes. DESIGN: A community-based, cross-sectional study. SETTING: This study was part of a longitudinal cohort study of a nurse-led health promotion programme for preventing foot ulceration in Chiayi County, Taiwan. PARTICIPANTS: Six hundred and twenty-eight community adults with type 2 diabetes participated in this study...
October 3, 2016: BMJ Open
Hubert Lenoir, Louis Dagneaux, François Canovas, Thomas Waitzenegger, Thuy Trang Pham, Michel Chammas
BACKGROUND: Neurologic lesions are relatively common after total shoulder arthroplasty. These injuries are mostly due to traction. We aimed to identify the arm manipulations and steps during reverse total shoulder arthroplasty (RTSA) that affect nerve stress. METHODS: Stress was measured in 10 shoulders of 5 cadavers by use of a tensiometer on each nerve from the brachial plexus, with shoulders in different arm positions and during different surgical steps of RTSA...
September 30, 2016: Journal of Shoulder and Elbow Surgery
R Barigye, S Davis, R Hunt, N Hunt, S Walsh, N Elliott, C Burnup, S Aumann, C Day, K Dyrting, R Weir, L F Melville
OBJECTIVE: This study assessed the neurotropism of bovine ephemeral fever (BEF) virus (BEFV) and described histomorphological abnormalities of the brain, spinal cord and peripheral nerves that may causally contribute to paresis or paralysis in BEF. METHODS: Four paralysed and six asymptomatic but virus-infected cattle were monitored, and blood and serum samples screened by qRT-PCR, virus isolation and neutralisation tests. Fresh brain, spinal cord, peripheral nerve and other tissues were qRT-PCR-tested for viral RNA, while formalin-fixed specimens were processed routinely and immunohistochemically evaluated for histomorphological abnormalities and viral antigen distribution, respectively...
October 2016: Australian Veterinary Journal
Abhinitha Padavinangadi, Naveen Kumar, Mohandas Kg Rao, Satheesha B Nayak
Chondroepitrochlearis (CET) is an anomalous muscular slip that originates from the pectoralis major muscle and inserts into epicondyle of the humerus. The morphology of this variant form of pectoralis major can vary from slender to strong musculo-tendinous. In its course, it usually crosses the neurovascular structures of arm; their compression is a major complication that could be manifested by its persistence. In the present case, potentially anomalous CET muscle with the slender slip of origin, but strong tendinous insertion to the medial epicondyle of the humerus was found unilaterally...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
Bryan G Beutel, Scott D Lifchez, Eitan Melamed
BACKGROUND: Cardiovascular procedures are common and are trending toward endovascular interventions. With this increase in endovascular procedures, there is also increasing awareness of upper extremity morbidity resulting from treatment. METHODS: Articles indexed within PubMed between the years 1975 and 2015 that discussed such complications were reviewed. RESULTS: Percutaneous radial artery access can lead to nerve ischemia, especially in the setting of an incomplete arterial arch, whereas radial artery harvesting for bypass surgery more commonly causes frank tissue ischemia and radial neuropathy...
August 2016: Journal of Hand and Microsurgery
Stephen Fisher, Vibhor Wadhwa, Christine Manthuruthil, Jonathan Cheng, Avneesh Chhabra
OBJECTIVES: To study the impact of brachial plexus magnetic resonance neurography (MRN) in diagnostic thinking and therapeutic management of patients with suspected plexopathy. METHODS: MRN examinations of adult brachial plexuses over a period of 18 months were reviewed. Relevant data collection included - patient demographics, clinical history, pre-imaging diagnostic impression, pre-imaging treatment plan, post-imaging diagnosis, post-imaging treatment plan, surgical notes, and electrodiagnostic (ED) results...
August 25, 2016: British Journal of Radiology
James Prueter, Shawn M Stevens, Norberto Andaluz, Ravi N Samy
OBJECTIVE: In this patient report, Parsonage-Turner syndrome (acute brachial neuropathy) developed in our patient 1 day after resection of a vestibular schwannoma by a middle cranial fossa approach. Aiming to increase awareness of this rare disorder among neurotologists, we describe differential diagnoses, work-up, and management strategies. PATIENT: A 67-year-old man treated for vestibular schwannoma at a single tertiary referral center. INTERVENTION: Surgery for vestibular schwannoma, electromyography for confirmation of diagnosis, and physical therapy...
September 2016: Otology & Neurotology
Jin-Dan Wu, Sha Tao, Xing Jin, Lan-Lan Jiang, Yun Shen, Yong Luo, Peng Zhang, Kok-Onn Lee, Lei Ye, Jian-Hua Ma
BACKGROUND: Diabetic peripheral neuropathy (DPN) is the most common chronic complication of diabetes. We aim to investigate the efficacy of Prostaglandin E1 (PGE1) treatment in addition to intensive insulin therapy on DPN in patients with type 2 diabetes. METHODS: Seventy-seven patients with DPN received daily intravenous injection of Prostaglandin E1 (PGE1) in lipid microspheres (Lipo-PGE1) for 10days as an additional therapy to standard glucose control therapy (PGE1 group)...
July 12, 2016: Prostaglandins & Other Lipid Mediators
Matthieu Roustit, Jordan Loader, Carly Deusenbery, Dimitrios Baltzis, Aristidis Veves
CONTEXT: Cardiovascular risk factors are well-known predictors of the development of diabetic peripheral neuropathy (DPN), which has traditionally been considered as a manifestation of diabetes-associated microangiopathy. Because endothelial dysfunction is strongly associated with all cardiovascular risk factors, we hypothesized that it may be a link between cardiovascular risk factors and DPN. OBJECTIVE: The primary objective of this study was to test whether endothelial dysfunction is a predictor of DPN...
September 2016: Journal of Clinical Endocrinology and Metabolism
Cristiane M Ida, Peter J Dyck, P James B Dyck, Janean K Engelstad, Wei Wang, Duygu Selcen, John B Bodensteiner, Michelle L Mauermann, Christopher J Klein
BACKGROUND: Pediatric neuropathies are both unique and similar to their adult counterparts, with genetic varieties thought to be more common. The objective of this work was to assess the utility of nerve biopsy in children at a tertiary referral center in light of availability of current genetic testing. METHODS: We retrospectively reviewed the clinical, nerve biopsy, and genetic testing findings of 316 pediatric (age ≤18 years) patients. RESULTS: Median age at diagnosis was 9...
May 2016: Pediatric Neurology
H L Codjo, T A Adoukonou, A Wanvoegbe, H Dohou, C Bankolé, A Alassani, C A Dovonou, D M Houénassi
We aimed to determine the prevalence of peripheral artery disease and its associated factors among diabetics. The cross-sectional study was conducted and included all diabetics admitted to the diabetic clinic at the Parakou University hospital during the period of 1st February and 31st July 2013. The diagnosis of peripheral artery disease was based on the Ankle Brachial Index (ABI)<0.9. The socio-demographics data, the data concerning the diabetes and its complications were recorded in each patient. They were 401 diabetics and 59...
September 2016: Annales de Cardiologie et D'angéiologie
Jodi M Carter, Benjamin M Howe, John R Hawse, Caterina Giannini, Robert J Spinner, Karen J Fritchie
Neuromuscular choristoma (NMC) is a very rare, developmental malformation characterized by the endoneurial intercalation of mature muscle fibers among peripheral nerve fibers. NMC typically arises in the major proximal peripheral nerves, most commonly the sciatic nerve, and may involve the lumbosacral and brachial plexus. Patients present clinically with progressive neuropathy or plexopathy. NMC is strongly associated with development of a fibromatosis, histologically identical to conventional desmoid-type fibromatosis (NMC-fibromatosis)...
October 2016: American Journal of Surgical Pathology
Rinko Kokubo, Kyongsong Kim, Toyohiko Isu, Daijiro Morimoto, Naotaka Iwamoto, Shiro Kobayashi, Akio Morita
OBJECTIVE: Tarsal tunnel syndrome (TTS) is an entrapment neuropathy of the posterior tibial nerve in the tarsal tunnel. It is not known whether vascular or neuropathic factors are implicated in the cause of a cold sensation experienced by patients. Therefore, we studied the cold sensation in the pedal extremities of patients who did or did not undergo TTS surgery. METHODS: Our study population comprised 20 patients with TTS (38 feet); 1 foot was affected in 2 patients and both feet in 18 patients...
August 2016: World Neurosurgery
Avneesh Chhabra, John A Carrino, Sahar J Farahani, Gaurav K Thawait, Charlotte J Sumner, Vibhor Wadhwa, Vinay Chaudhary, Thomas E Lloyd
PURPOSE: To evaluate the feasibility of whole-body magnetic resonance neurography (WBMRN) in polyneuropathy for technical feasibility, distribution of nerve abnormalities, and differentiation. MATERIALS AND METHODS: Twenty WBMRN examinations were performed on a 3T scanner over 2 years. Patient demographics including history of hereditary and acquired neuropathy were recorded. The images were evaluated by two independent readers with nerve imaging experience for quality...
April 29, 2016: Journal of Magnetic Resonance Imaging: JMRI
Slavisa Ninkovic, Chan Y Cheah, Arian Lasocki, Simon James Harrison
No abstract text is available yet for this article.
April 27, 2016: Leukemia & Lymphoma
Alhasan Elghouche, Tom Shokri, Yewen Qin, Susannah Wargo, Deborah Citrin, Carter Van Waes
We report a constellation of cervical polyneuropathies in a patient treated with concurrent bortezomib, cetuximab, and cisplatin alongside intensity modulated radiotherapy for carcinoma of the tonsil with neck metastasis. The described deficits include brachial plexopathy, cervical sensory neuropathy, and oculosympathetic, recurrent laryngeal, and phrenic nerve palsies within the ipsilateral radiation field. Radiation neuropathy involving the brachial plexus is typically associated with treatment of breast or lung cancer; however, increased awareness of this entity in the context of investigational agents with potential neuropathic effects in head and neck cancer has recently emerged...
2016: Case Reports in Otolaryngology
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