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https://www.readbyqxmd.com/read/28930780/splinting-after-ear-reconstruction-a-stepwise-and-inexpensive-workflow-protocol
#1
Herman Vercruysse, James I J Green, Gaynor Osman, Brigitte Harrison, Kana Miyagi, Neil W Bulstrode
BACKGROUND: Long-term postoperative splinting plays a role in the prevention of contracture of the grafted skin after a second-stage ear reconstruction. The scar retraction could lead to an unfavorable aesthetic outcome. Splinting could play a role to overcome or prevent the loss of projection and the obliteration of the sulcus. MATERIAL AND METHODS: We have defined the characteristics of an ideal long-term splint and present a stepwise clinical protocol for the fabrication of an ethylene-vinyl acetate splint...
September 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28929069/our-experience-of-treating-wide-spectrum-of-external-ear-canal-atresia-of-different-etiologies-in-pediatric-patients
#2
Kranti Bhavana
External auditory canal atresia (EACA) is a common otologic condition. Etiology can vary from congenital to acquired causes. It causes considerable difficulty to the patient. Bilateral ear canal atresia in children can lead to speech delays due to hearing impairment caused by this condition. Though easily diagnosed it is one of the most difficult conditions to treat. Acquired conditions can affect any age group. Restenosis following treatment is very common. This article focuses on the treatment of EACA due to different etiologies and emphasizes on special points of surgical treatment and follow up...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28926877/-clinical-effects-of-repair-of-wounds-in-fingers-after-electrical-burn-with-wrist-perforator-free-flaps
#3
H P Di, C D Xia, P P Xing, Q Li, D W Han, J D Xue, D Y Cao
Objective: To explore the clinical effects of repair of wounds in the fingers after electrical burn with wrist perforator free flaps. Methods: Twelve patients (13 fingers) with electrical burn were hospitalized in our burn ward from January 2016 to January 2017. After radical debridement, the size of wounds ranged from 5.0 cm×2.0 cm to 10.0 cm×7.0 cm. Wounds with size below or equal to 6.0 cm ×2.5 cm were repaired with free flaps based on the superficial palmar branch of radial artery, with flap area ranging from 2...
September 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28926875/-effects-of-perforator-flaps-combined-with-muscle-flaps-for-repairing-grade-%C3%A2-pressure-ulcers-in-ischial-tuberosity-of-elderly-patients
#4
W G Su, D P Li, P P Xing, L G Xu, F C Shi, B Wen, X H Niu
Objective: To explore effects of perforator flaps combined with muscle flaps for repairing grade Ⅳ pressure ulcers in ischial tuberosity of elderly patients. Methods: Nine elderly patients with grade Ⅳ pressure ulcers in ischial tuberosity were hospitalized in our burn ward from April 2014 to April 2017. Size of wounds ranged from 5 cm×3 cm to 12 cm×7 cm, and depth of sinus ranged from 6 to 22 cm. After admission, emergency debridement or debridement in selective time was performed. After debridement, the wounds were treated with continuous vacuum assisted closure therapy...
September 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28926874/-multicenter-epidemiological-investigation-of-hospitalized-elderly-young-and-middle-aged-patients-with-severe-burn
#5
Y Tang, L X Wang, W G Xie, Z A Shen, G H Guo, J J Chen, C M Han, L C Ren, Z G Chu, M F Yin, Y Wang, D X Zhang, Y S Huang, J P Zhang
Objective: To compare and analyze the epidemiological characteristics of hospitalized elderly, young and middle-aged patients with severe burn in recent years, so as to provide reference for the prevention and treatment of elderly patients with severe burn. Methods: Relying on the entry system of epidemiological case data and biological sample of severe burn from multicenter in clinic, medical records of patients with severe burn, aged above 18, hospitalized in 8 burn wards from January 2012 to December 2015 were collected...
September 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28925493/repair-and-sensory-reconstruction-of-the-children-s-finger-pulp-defects-with-perforator-pedicled-propeller-flap-in-proper-digital-artery
#6
S-M Feng, A-G Wang, Z-Y Zhang, Q-Q Sun, Y-L Tao, M-M Zhou, Y-J Hao
OBJECTIVE: This study was designed to investigate the clinical effects of adopting perforator pedicled propeller flap in the proper digital artery for treatment and sensory reconstruction of finger pulp defects in children. PATIENTS AND METHODS: Perforator pedicled propeller flap of proper digital arteries in thirty-one fingers from twenty-three children patients were selected for repairing the pulp defects on the 2nd to the 5th fingers. All cases were treated from September 2012 to December 2013...
August 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28922518/accelerated-epithelialization-and-improved-wound-healing-metrics-in-porcine-full-thickness-wounds-transplanted-with-full-thickness-skin-micrografts
#7
Christina L Rettinger, John L Fletcher, Anders H Carlsson, Rodney K Chan
Split-thickness skin grafting (STSG) is the current gold standard for treatment of extensive burn and traumatic skin injuries. However, STSG is limited by donor-site morbidity and availability, and often leads to scarring and wound contracture. Furthermore, these thin grafts lack dermal elements such as nerves and adnexa which are important in recapitulating normal skin function. Methods of fractional skin replacement either as minced STSGs or microscopic skin tissue columns (MSTCs) have been proposed, though these techniques have not been fully-characterized and lack evidence of regenerated adnexal structures...
September 18, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28922244/fibular-graft-effective-panorama-for-prosthetic-rehabilitation-of-resected-mandible
#8
Pankaj Kharade, Saidul Islam, Mahesh Verma, Swati Sharma, Ranjeet Bodh
Surgical management of extensive tumors in the mandibular region leads to massive disfigurement of the face. Also the prosthetic outcome of such patients rehabilitated with free soft tissue flaps is very poor. Reconstruction of extensive defects to overcome the disfigurement is a challenging procedure and can be achieved with free fibula flap. Free fibula graft provides sufficient length of bone for the reconstruction of the postsurgical defects. Excellent vascularity of fibula flap allows for easy uptake of the graft and osseointegration of the dental implants...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28918934/reconstructive-microsurgical-approach-for-the-treatment-of-pyoderma-gangrenosum
#9
Karl Schwaiger, Elisabeth Russe, Hassan Kholosy, Michaela Hladik, Klemens Heinrich, Laurenz Weitgasser, Thomas Schoeller, Gottfried Wechselberger
INTRODUCTION: Pyoderma gangrenosum (PG) is a rare type of autoimmune disease that results in progressive ulcers with or without previous trauma. However, PG is not well understood to date, and its treatment therefore remains a challenge. Because of the disease's systemic characteristic and the unpredictability of the clinical course, no gold standard treatment is available, especially concerning the surgical procedures to treat pyodermic lesions. Often, PG is not recognized during routine clinical practice, and standard ulcer treatment (conservative wound care, debridement, skin grafting, and local flap coverage) is initiated; this induces an autoinflammatory response, resulting in disastrous ulcers, thereby making free flap coverage necessary...
August 16, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28917923/effect-of-carboxymethylation-on-rheological-and-drug-release-characteristics-of-terminalia-catappa-gum
#10
Radhika Sharma, Vikas Rana
The carboxymethylation of galactomannans, arabinogalactans, arbinoxylan, etc is known to modify solubility, swelling index, rheological behaviour, powder characteristics, etc. Therefore, an attempt had been made to study the effect of carboxymethylation on Terminalia catappa (TC) gum. For this, modified Williamson synthesis reaction was utilized employing Quality by Design (QbD) approach. Grafting of carboxymethyl group on Terminalia catappa was confirmed by ATR-FTIR, H(1)NMR and DSC analyses. The rheological attributes revealed that the carboxymethylation of TC lowers the viscosity, enhance thermal stability (high activation energy), disentanglement was near to re-entanglement, and weak gelling characteristic...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28915833/deltopectoral-flap-revisited-for-reconstruction-surgery-in-patients-with-advanced-thyroid-cancer-a-case-report
#11
Taro Mikami, Shintaro Kagimoto, Yuichiro Yabuki, Kazunori Yasumura, Toshinori Iwai, Jiro Maegawa, Nobuyasu Suganuma, Shohei Hirakawa, Katsuhiko Masudo
BACKGROUND: We present the cases of 2 patients with invasive thyroid cancer, who underwent reconstructive surgery using a deltopectoral flap. Although the overall rate of extrathyroidal extension in patients with thyroid cancer is quite low, skin invasion is the most common pattern observed. Reconstructive surgery, involving local skin flaps, is required in these patients. The deltopectoral flap relies on the blood supply from intercostal perforators of the internal thoracic artery and usually requires skin grafting to the donor site...
September 15, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28914704/rectoneovaginal-fistula-in-a-transgender-woman-successfully-repaired-using-a-buccal-mucosa-graft
#12
Molly Abbott Elmer-DeWitt, Hadley M Wood, Tracy Hull, Cecile A Unger
BACKGROUND: Rectoneovaginal fistulae (RnVFs) are abnormal connections between the rectum and a surgically created neovagina. Although very uncommon, they confer significant morbidity in patients and may require a multidisciplinary team approach to the repair. Risk factors for RnVF include rectal injury at the time of neovaginoplasty, malignancy in the neovagina, trauma (iatrogenic or otherwise), radiation, and neovaginal revision surgery. CASE DESCRIPTION: The patient is a 64-year-old transgender woman with recurrent RnVF following penile skin inversion neovaginoplasty, which was complicated by an intraoperative rectal injury...
September 13, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28913317/reconstruction-of-a-complex-scalp-defect-after-the-failure-of-free-flaps-changing-plans-and-strategy
#13
Youn Hwan Kim, Gyeong Hoe Kim, Sang Wha Kim
The ideal scalp reconstruction involves closure of the defect with similar hair-bearing local tissue in a single step. Various reconstructions can be used including primary closure, secondary healing, skin grafts, local flaps, and microvascular tissue transfer. A 53-year-old female patient suffered glioblastoma, which had recurred for the second time. The neurosurgeons performed radial debridement and an additional resection of the tumor, followed by reconstruction using a serratus anterior muscle flap with a split-thickness skin graft...
June 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28913304/trichilemmal-carcinoma-from-proliferating-trichilemmal-cyst-on-the-posterior-neck
#14
Ui Geon Kim, Dong Bee Kook, Tae Hun Kim, Chung Hun Kim
Trichilemmal cysts are common fluid-filled growths that arise from the isthmus of the hair follicle. They can form rapidly multiplying trichilemmal tumors-, also called proliferating trichilemmal cysts, which are typically benign. Rarely, proliferating trichilemmal cysts can become cancerous. Here we report the case of a patient who experienced this series of changes. The 27-year-old male patient had been observed to have a 1×1 cm cyst 7 years ago. Eight months prior to presentation at our institution, incision and drainage was performed at his local clinic...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28913291/immediate-near-total-scalp-reconstruction-with-artificial-dermis-on-exposed-calvarium
#15
Sooyeon Park, Ki Taik Han, Min Cheol Kim, Jin Soo Lim
Scalp defect management is complicated secondary to reduced laxity in the scalp and forehead area. For reconstruction of larger defects with exposed bone and loss of the periosteal layer, free flap reconstruction is one option for single-stage surgery, although the procedure is lengthy and includes the possibility of flap loss. We successfully performed a single-stage reconstruction of a large scalp defect using a combination of artificial dermis, split-thickness skin graft, and full-thickness skin graft following wide excision of a cutaneous angiosarcoma, and present our method as one option for the treatment of large oncologic surgical defects in patients who are poor candidates for free flap surgery...
December 2016: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28913282/the-versatility-of-cheek-rotation-flaps
#16
Kyung Pil Kim, Ho Seup Sim, Jun Ho Choi, Sam Yong Lee, Do Hun Lee, Seong Hwan Kim, Hong Min Kim, Jae Ha Hwang, Kwang Seog Kim
BACKGROUND: The cheek rotation flap has sufficient blood flow and large flap size and it is also flexible and easy to manipulate. It has been used for reconstruction of defects on cheek, lower eyelid, or medial and lateral canthus. For the large defects on central nose, paramedian forehead flap has been used, but patients were reluctant despite the remaining same skin tone on damaged area because of remaining scars on forehead. However, the cheek flap is cosmetically superior as it uses the adjacent large flap...
December 2016: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28912844/triptolide-inhibits-cd4-memory-t-cell-mediated-acute-rejection-and-prolongs-cardiac-allograft-survival-in-mice
#17
Shuiwei Qiu, Dingliang Lv
There have been numerous investigations into the immunosuppressive effects of triptolide; however, its inhibitory effects on memory T cells remain to be elucidated. Using a cluster of differentiation (CD)4(+) memory T-cell transfer model, the aim of the present study was to determine the inhibitory effects of triptolide on CD4(+) memory T cell-mediated acute rejection and to determine the potential underlying mechanisms. At 4 weeks after skin transplantation, mouse cervical heart transplantation was performed following the transfer of CD4(+) memory T cells...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28912374/collagen-embedded-tumor-transplantations-in-xenopus-laevis-tadpoles
#18
Maureen Banach, Jacques Robert
The Xenopus laevis tadpole provides a valuable model for studying tumorigenesis and tumor immunity by intravital real-time microscopy. Using well-characterized thymic lymphoid tumor lines (15/0 and ff-2) that are transplantable into their compatible hosts (LG-15 isogenic clones and the F inbred strain, respectively), a system of semisolid tumor engraftment has been designed. Because these lymphoid tumor cell lines are not adherent and grow in suspension, they are first immobilized in a matrix of type I rat tail collagen before transplantation as a semisolid tumor graft under the transparent dorsal skin in the head region of a tadpole...
September 14, 2017: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/28906595/superiority-of-occipital-donor-sites-for-split-thickness-skin-grafting-in-dermatosurgery-results-of-a-prospective-randomized-controlled-study
#19
Maximilian Kovacs, Syrus Karsai, Maurizio Podda
BACKGROUND: Split-thickness skin grafts are commonly used in dermatosurgery. For occipital donor sites, retrospective studies have shown good results with respect to graft take and healing rates. Nevertheless, the majority of grafts in dermatosurgery are harvested from the thigh. To date, there has been no prospective randomized controlled study comparing occipital versus femoral donor sites. PATIENTS AND METHODS: Following micrographically controlled R0 tumor resection, 108 patients were randomized prior to undergoing split-thickness skin grafting (donor site: occiput vs...
September 14, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28906302/chemotherapy-extravasation-management-21-year-experience
#20
Maria Giuseppina Onesti, Sara Carella, Paolo Fioramonti, Nicolò Scuderi
Chemotherapy extravasation may result in serious damage to patients, with irreversible local injures and disability. Evidence-based standardization on extravasation management is lacking and many institutions do not practice adequate procedures to prevent the severer damages. Our aim was to explore the prevention and treatment of extravasation injuries, proposing a standard therapeutic protocol together with a review of the literature. From January 1994 to December 2015, 545 cases were reviewed (age range, 5-87 years; 282 men and 263 women)...
September 12, 2017: Annals of Plastic Surgery
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