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https://www.readbyqxmd.com/read/28446868/triggering-avoidance-dissociable-influences-of-aversive-pavlovian-conditioned-stimuli-on-human-instrumental-behavior
#1
Sara Garofalo, Trevor W Robbins
The present study investigates human aversive Pavlovian-to-Instrumental Transfer (PIT) and possible influences of outcome devaluation and instrumental overtraining on this effect. PIT measures the extent to which a Pavlovian conditioned stimulus (CS) can increase instrumental responses independently paired with the same (outcome-specific transfer) or a different (general transfer) reinforcer. Two measures of PIT were obtained: the percentage of instrumental responses and the vigor of such responses. Thirty-eight volunteers performed a standard PIT task sequence...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28422588/alterations-in-redox-homeostasis-during-recovery-from-unexplained-underperformance-syndrome-in-an-elite-international-rower
#2
Nathan A Lewis, Ann Redgrave, Mark Homer, Richard Burden, Wendy Martinson, Brian Moore, Charles R Pedlar
PURPOSE: This case study of an international rower examines a diagnosis of Unexplained Under Performance Syndrome (UUPS or Overtraining Syndrome) describing a full recovery and return to elite competition the same year. METHODS: On diagnosis and 4 and 14 months post-diagnosis, detailed assessments including physiological, nutritional, and biomarkers were made. RESULTS: Clinical examination and laboratory results for haematology, biochemistry, thyroid function, immunology, vitamins and minerals were unremarkable and did not explain the presentation and diagnosis...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28408889/effects-of-sesame-sesamum-indicum-l-supplementation-on-creatine-kinase-lactate-dehydrogenase-oxidative-stress-markers-and-aerobic-capacity-in-semi-professional-soccer-players
#3
Carlos V da Silva Barbosa, Alexandre S Silva, Caio V C de Oliveira, Nayara M L Massa, Yasmim R F de Sousa, Whyara K A da Costa, Ayice C Silva, Plínio Delatorre, Rhayane Carvalho, Valdir de Andrade Braga, Marciane Magnani
Nutritional intervention with antioxidants rich foods has been considered a strategy to minimize the effects of overtraining in athletes. This experimental, randomized, and placebo-controlled study evaluated the effects of consumption of sesame (Sesamum indicum L.) on muscle damage markers, oxidative stress, systemic inflammation, and aerobic performance in male semi-professional soccer players. Twenty athletes were randomly assigned to groups that received 40 g (two tablespoons) per day of sesame or a placebo during 28 days of regular training (exposed to routine training that includes loads of heavy training in the final half of the season)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28342242/a-systematic-analysis-of-scoring-functions-in-rigid-body-protein-docking-the-delicate-balance-between-the-predictive-rate-improvement-and-the-risk-of-overtraining
#4
Didier Barradas-Bautista, Iain H Moal, Juan Fernández-Recio
Protein-protein interactions play fundamental roles in biological processes including signaling, metabolism and trafficking. While the structure of a protein complex reveals crucial details about the interaction, it is often difficult to acquire this information experimentally. As the number of interactions discovered increases faster than they can be characterized, protein-protein docking calculations may be able to reduce this disparity by providing models of the interacting proteins. Rigid-body docking is a widely used docking approach, and is often capable of generating a pool of models within which a near-native structure can be found...
March 25, 2017: Proteins
https://www.readbyqxmd.com/read/28306393/circannual-rhythm-of-plasmatic-vitamin-d-levels-and-the-association-with-markers-of-psychophysical-stress-in-a-cohort-of-italian-professional-soccer-players
#5
Giovanni Lombardi, Jacopo Antonino Vitale, Sergio Logoluso, Giovanni Logoluso, Nino Cocco, Giulio Cocco, Antonino Cocco, Giuseppe Banfi
Adequate plasmatic Vitamin D levels are crucial to maintain calcium homeostasis and bone metabolism both in the general population and in athletes. Correct dietary supply and a regular sun exposure are fundamental for allowing the desired and effective fitness level. Past studies highlighted a scenario of Vitamin D insufficiency among professional soccer players in several countries, especially in North Europe, whilst a real deficiency in athletes is rare. The typical seasonal fluctuations of Vitamin D are wrongly described transversally in athletes belonging to teams that play at different latitudes and a chronobiologic approach studying the Vitamin D circannual rhythm in soccer players has not been described yet...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28265245/passion-and-pacing-in-endurance-performance
#6
Lieke Schiphof-Godart, Florentina J Hettinga
Endurance sports are booming, with sports passionates of varying skills and expertise battering city streets and back roads on their weekly or daily exercise rounds. The investments required for performing in endurance exercise are nevertheless considerable, and passion for their sport might explain the efforts endurance athletes are willing to make. Passion may be defined as a strong motivational force and as such might be related to the neurophysiological basis underlying the drive to exercise. A complex relationship between the brain and other systems is responsible for athletes' exercise behavior and thus performance in sports...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28240299/identification-of-an-unconventional-process-of-instrumental-learning-characteristically-initiated-with-outcome-devaluation-insensitivity-and-generalized-action-selection
#7
Yoshio Iguchi, Ziqiao Lin, Hiromi Nishikawa, Yoshio Minabe, Shigenobu Toda
The distinction between goal-directed action and habitual response, particularly with respect to moderate or extended appetitive instrumental training, is well documented; however, the propensity toward instrumental behavior in the early training stage has not been elucidated. In this study, we trained Sprague Dawley rats to press a lever to obtain food as an outcome for various time periods and monitored the changes in their sensitivity to outcome devaluation and choice between the levers they had been trained with and unfamiliar levers...
February 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28177743/excessive-training-is-associated-with-endoplasmic-reticulum-stress-but-not-apoptosis-in-the-hypothalamus-of-mice
#8
Ana Paula Pinto, Alisson Luiz da Rocha, Bruno Cesar Pereira, Luciana da Costa Oliveira, Gustavo Paroschi Morais, Leandro Pereira Moura, Eduardo Rochete Ropelle, José Rodrigo Pauli, Adelino Sanchez Ramos da Silva
Downhill running-based overtraining model increases the hypothalamic levels of IL-1β, TNF-α, SOCS3, and pSAPK-JNK. The aim of the present study was to verify the effects of 3 overtraining protocols on the levels of BiP, pIRE-1 (Ser724), pPERK (Thr981), pelF2α (Ser52), ATF-6, GRP-94, caspase 4, caspase 12, pAKT (Ser473), pmTOR (Ser2448), and pAMPK (Thr172) proteins in the mouse hypothalamus. The mice were randomized into the control, overtrained by downhill running (OTR/down), overtrained by uphill running (OTR/up), and overtrained by running without inclination (OTR) groups...
December 5, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27966392/changes-in-cytokines-leptin-and-igf-1-levels-in-overtrained-athletes-during-a-prolonged-recovery-phase-a-case-control-study
#9
Raimo Joro, Arja Uusitalo, Keith C DeRuisseau, Mustafa Atalay
We investigated how cytokines are implicated with overtraining syndrome (OTS) in athletes during a prolonged period of recovery. Plasma IL-6, IL-10, TNF-α, IL-1β, adipokine leptin, and insulin like growth factor-1 (IGF-1) concentrations were measured in overtrained (OA: 5 men, 2 women) and healthy control athletes (CA: 5 men, 5 women) before and after exercise to volitional exhaustion. Measurements were conducted at baseline and after 6 and 12 months. Inflammatory cytokines did not differ between groups at rest...
December 14, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27941492/effects-of-a-modified-german-volume-training-program-on-muscular-hypertrophy-and-strength
#10
Theban Amirthalingam, Yorgi Mavros, Guy C Wilson, Jillian L Clarke, Lachlan Mitchell, Daniel A Hackett
German Volume Training (GVT), or the 10 sets method, has been used for decades by weightlifters to increase muscle mass. To date, no study has directly examined the training adaptations following GVT. The purpose of this study was to investigate the effect of a modified GVT intervention on muscular hypertrophy and strength. Nineteen healthy males were randomly assign to 6 weeks of 10 or 5 sets of 10 repetitions for specific compound resistance exercises included in a split-routine performed 3 times per week...
November 25, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27920726/hrvanalysis-a-free-software-for-analyzing-cardiac-autonomic-activity
#11
Vincent Pichot, Frédéric Roche, Sébastien Celle, Jean-Claude Barthélémy, Florian Chouchou
Since the pioneering studies of the 1960s, heart rate variability (HRV) has become an increasingly used non-invasive tool for examining cardiac autonomic functions and dysfunctions in various populations and conditions. Many calculation methods have been developed to address these issues, each with their strengths and weaknesses. Although, its interpretation may remain difficult, this technique provides, from a non-invasive approach, reliable physiological information that was previously inaccessible, in many fields including death and health prediction, training and overtraining, cardiac and respiratory rehabilitation, sleep-disordered breathing, large cohort follow-ups, children's autonomic status, anesthesia, or neurophysiological studies...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27918673/predictive-indicators-of-overuse-injuries-in-adolescent-endurance-athletes
#12
Daniel Martínez-Silván, Jaime Díaz-Ocejo, Andrew Murray
PURPOSE: To analyse the influence of training exposure and the utility of self-report questionnaires on predicting overuse injuries in adolescent endurance athletes. METHODS: 5 adolescent male endurance athletes (15.7 ± 1.4 yr) from a full-time sports academy answered 2 questionnaires (Recovery Cue; RC-q & Oslo Sports Trauma Research questionnaire; OSTRC-q) on a weekly basis for one season (37 wks) in order to detect (1) signs of overtraining and under-recovery (RC-q) and (2) early symptoms of lower limb injuries (OSTRC-q)...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27918270/interaction-of-inhibitory-and-facilitatory-effects-of-conditioning-trials-on-long-term-memory-formation
#13
Shouhei Hosono, Yukihisa Matsumoto, Makoto Mizunami
Animals learn through experience and consolidate the memories into long-time storage. Conditioning parameters to induce protein synthesis-dependent long-term memory (LTM) have been the subject of extensive studies in many animals. Here we found a case in which a conditioning trial inhibits or facilitates LTM formation depending on the intervals from preceding trials. We studied the effects of conditioning parameters on LTM formation in olfactory conditioning of maxillary-palpi extension response with sucrose reward in the cockroach Periplaneta americana We found, at first, that translation- and transcription-dependent LTM forms 1 h after training, the fastest so far reported in insects...
December 2016: Learning & Memory
https://www.readbyqxmd.com/read/27889430/classification-of-teeth-in-cone-beam-ct-using-deep-convolutional-neural-network
#14
Yuma Miki, Chisako Muramatsu, Tatsuro Hayashi, Xiangrong Zhou, Takeshi Hara, Akitoshi Katsumata, Hiroshi Fujita
Dental records play an important role in forensic identification. To this end, postmortem dental findings and teeth conditions are recorded in a dental chart and compared with those of antemortem records. However, most dentists are inexperienced at recording the dental chart for corpses, and it is a physically and mentally laborious task, especially in large scale disasters. Our goal is to automate the dental filing process by using dental x-ray images. In this study, we investigated the application of a deep convolutional neural network (DCNN) for classifying tooth types on dental cone-beam computed tomography (CT) images...
November 12, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27845474/risk-of-infectious-mononucleosis-among-agonistic-swimmers-a-cross-sectional-study
#15
M S Gallone, L Astuto, G Mastrorilli, R Tamma, L Ascatigno, D Sinesi, A Notarnicola, S Tafuri
BACKGROUND: The risk of infectious mononucleosis among athletes is quite debated. Some personal observations seem to suggest an increase risk of mononucleosis among athletes, because they attend always close settings with an high probability of respiratory pathogens transmission; overtraining has been also proposed as risk factor. STUDY DESIGN: Cross-sectional study in a group of swimmers (aged 11-14 years) of the University Sport Centre of Bari. METHODS: 40 swimmers were interviewed by healthcare personnel at the end of training courses; demographic characteristics, personal habits, information about sport training and diagnosis of mononucleosis were analysed...
November 2016: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/27782053/circulating-micrornas-as-potential-biomarkers-of-exercise-response
#16
REVIEW
Mája Polakovičová, Peter Musil, Eugen Laczo, Dušan Hamar, Ján Kyselovič
Systematic physical activity increases physical fitness and exercise capacity that lead to the improvement of health status and athletic performance. Considerable effort is devoted to identifying new biomarkers capable of evaluating exercise performance capacity and progress in training, early detection of overtraining, and monitoring health-related adaptation changes. Recent advances in OMICS technologies have opened new opportunities in the detection of genetic, epigenetic and transcriptomic biomarkers. Very promising are mainly small non-coding microRNAs (miRNAs)...
October 5, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27771800/changes-in-resting-mitogen-activated-protein-kinases-following-resistance-exercise-overreaching-and-overtraining
#17
Justin X Nicoll, Andrew C Fry, Andrew J Galpin, Adam J Sterczala, Donald B Thomason, Christopher A Moore, Lawrence W Weiss, Loren Z F Chiu
PURPOSE: Many physiological maladaptations persist after overreaching and overtraining resistance exercise (RE). However, no studies have investigated changes in mitogen-activated protein kinases (MAPK) after overtraining in humans, despite their critical role regulating exercise-induced muscular adaptations. The purpose of this study was to describe the changes in total and resting phosphorylation status of extracellular signal-regulated kinase 1/2 (ERK1/2), c-Jun NH2-terminal kinase (JNK) and p38-MAPK following a period of RE overreaching or overtraining...
December 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27767967/one-year-follow-up-of-blood-viscosity-factors-and-hematocrit-viscosity-ratio-in%C3%A2-elite-soccer-players
#18
Jean-Frédéric Brun, Emmanuelle Varlet-Marie, Christine Fédou, Eric Raynaud de Mauverger
We investigated to what extent a prediction of the 'ideal' hematocrit based on individual hemorheological profile with an equation of viscosity is relevant in trained athletes, and how the agreement between theoretical and actual values is modified by changes in training volume and performance. Elite soccer players (national level: 18-32 yr, weight 61-83 kg, body mass index 20.9-25.8 kg/m2) were seen twice at one year interval. Hemorheologic parameters were measured with the MT90 viscometer and the Myrenne aggregometer the theoretical bell-shaped curve of hematocrit/viscosity ratio as a function of hematocrit was reconstructed with Quemada's equation using actual plasma viscosity and red cell rigidity to predict hematocrit/viscosity at various hematocrit levels...
2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27767965/hematocrit-and-hematocrit-viscosity-ratio-during-exercise-in-athletes-even-closer-to-predicted-optimal-values
#19
Jean-Frédéric Brun, Emmanuelle Varlet-Marie, Eric Raynaud de Mauverger
The hemorheological theory of optimal hematocrit suggests that the best value of hematocrit (hct) should be that which results in the highest value of the hematocrit/viscosity (h/η) ratio. Trained athletes compared to sedentary subjects have a lower hct, but a higher h/η, and endurance training reduces the discrepancy between the actual hct and the ⪡ideal⪢ hct that can be predicted with a theoretical curve of h/η vs hct constructed with Quemada's model. In this study we investigated what becomes this homeostasis of h/η and hct during acute exercise in 19 athletes performing a 25 min exercise test...
2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27751748/-intensive-training-and-menstrual-disorders-in-young-female-impact-on-bone-mass
#20
L Maïmoun, F Paris, O Coste, C Sultan
Participation in recreational physical activity is widely acknowledged to provide significant health benefits. Conversely, intense training imposes several constraints, such as intermittent or chronic metabolic and psychogenic training stressors and maintenance of very low body fat to maximize performance. Adolescent and adult athletic women are therefore at risk of overtraining and/or poor dietary intake, which may have several consequences for endocrine function particularly on hypothalamic-pituitary-gonadal axis...
November 2016: Gynécologie, Obstétrique & Fertilité
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