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https://www.readbyqxmd.com/read/27893622/image-quality-and-artifacts-on-optical-coherence-tomography-angiography-comparison-of-pathologic-and-paired-fellow-eyes-in-65-patients-with-unilateral-choroidal-melanoma-treated-with-plaque-radiotherapy
#1
Emil A T Say, Sandor Ferenczy, George N Magrath, Wasim A Samara, Chloe T L Khoo, Carol L Shields
PURPOSE: To study image quality and artifacts seen on optical coherence tomography angiography (OCTA). METHODS: Sixty-five consecutive patients with unilateral posterior uveal melanoma treated with plaque radiotherapy had OCTA during follow-up. Optical coherence tomography angiography was performed on both the affected and fellow eye. Signal strength and frequency of image artifacts on en face images were compared between affected and fellow eyes. RESULTS: A total of 130 eyes in 65 patients were analyzed, the mean age at time of OCTA was 55 years (median: 56, range: 12-81 years), and 39 (39/65, 60%) were female...
November 23, 2016: Retina
https://www.readbyqxmd.com/read/27843899/dissecting-aortic-aneurysm-55-years-after-diagnosis-of-iris-flocculi
#2
Jerry A Shields, George N Magrath, Carol Shields, Richard Mackool, Ralph C Eagle, Hans E Grossniklaus
PURPOSE: The aim of this study is to report the clinical features, imaging studies, surgical removal, and pathology of congenital iris flocculi in a patient who developed a life-threatening dissecting aortic aneurysm after 55 years of follow-up. METHODS: Documentation with iris photography was performed from age 18 to 55 years, at which time anterior segment optical coherence tomography (OCT) was performed. At the time of subsequent cataract surgery, the iris flocculi were removed in each eye and submitted for light and electron microscopy...
October 2016: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27843235/flat-choroidal-melanoma-masquerading-as-central-serous-chorioretinopathy
#3
Timothy Patrick Higgins, Chloe T L Khoo, George Magrath, Carol L Shields
There are several mimickers of choroidal melanoma. We report a patient with recent family stress who developed blurred vision to 20/50 OD and was found to have unilateral central serous chorioretinopathy and a coincidental choroidal nevus. After 1 year without resolution of the subretinal fluid, the patient was referred for our opinion. On examination, visual acuity was 20/50 in the right eye and 20/20 in the left eye. The left eye was normal. Evaluation of the right eye showed a small, pigmented submacular choroidal lesion measuring 4 mm × 3 mm...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27797395/continuity-change-and-complexity-in-the-performance-of-masculinity-among-elite-young-footballers-in-england
#4
Steven Roberts, Eric Anderson, Rory Magrath
Following recent research evidencing that young men are redefining the essential components of what it is to be a man, this paper draws on qualitative interviews with 22 elite-level, English Premier League academy level football (soccer) players to investigate their performances and understandings of masculinity in relation to decreasing homohysteria. Even in this gender-segregated, near-total institution, these working-class, non-educationally aspiring adolescents evidence an attenuated performance of 'maleness' and improved attitudinal disposition toward homosexuality...
October 31, 2016: British Journal of Sociology
https://www.readbyqxmd.com/read/27232466/parafoveal-capillary-density-after-plaque-radiotherapy-for-choroidal-melanoma-analysis-of-eyes-without-radiation-maculopathy
#5
Emil Anthony T Say, Wasim A Samara, Chloe T L Khoo, George N Magrath, Priya Sharma, Sandor Ferenczy, Carol L Shields
PURPOSE: To study the parafoveal capillary density using optical coherence tomography angiography (OCTA) in eyes treated with plaque radiotherapy. RESEARCH DESIGN: Retrospective comparative case series. PARTICIPANTS: Ten patients treated with plaque radiotherapy for choroidal melanoma without evident radiation maculopathy on ophthalmoscopy or optical coherence tomography were imaged with OCTA. MAIN OUTCOME MEASURE: Comparison of the parafoveal capillary density in the superficial and deep capillary plexuses in the irradiated versus fellow nonirradiated eye...
September 2016: Retina
https://www.readbyqxmd.com/read/26820991/scope-for-genetic-rescue-of-an-endangered-subspecies-though-re-establishing-natural-gene-flow-with-another-subspecies
#6
Katherine A Harrisson, Alexandra Pavlova, Anders Gonçalves da Silva, Rebecca Rose, James K Bull, Melanie L Lancaster, Neil Murray, Bruce Quin, Peter Menkhorst, Michael J L Magrath, Paul Sunnucks
Genetic diversity is positively linked to the viability and evolutionary potential of species but is often compromised in threatened taxa. Genetic rescue by gene flow from a more diverse or differentiated source population of the same species can be an effective strategy for alleviating inbreeding depression and boosting evolutionary potential. The helmeted honeyeater Lichenostomus melanops cassidix is a critically endangered subspecies of the common yellow-tufted honeyeater. Cassidix has declined to a single wild population of ~130 birds, despite being subject to intensive population management over recent decades...
March 2016: Molecular Ecology
https://www.readbyqxmd.com/read/26765038/unilateral-retinoblastoma-managed-with-intravenous-chemotherapy-versus-intra-arterial-chemotherapy-outcomes-based-on-the-international-classification-of-retinoblastoma
#7
Carol L Shields, Rodrigo Jorge, Emil Anthony T Say, George Magrath, Adel Alset, Emi Caywood, Ann M Leahey, Pascal Jabbour, Jerry A Shields
PURPOSE: The objective of this study was to compare outcomes after intravenous chemotherapy (IVC) versus intra-arterial chemotherapy (IAC) for unilateral retinoblastoma. DESIGN: A retrospective comparative interventional case series. METHODS: Patients with unilateral retinoblastoma managed with either IVC using vincristine, etoposide, and carboplatin or IAC using melphalan with or without topotecan with a minimum of 1-year follow-up were compared...
March 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/26679982/hearing-is-believing-birds-learn-fear
#8
Christopher B Sturdy, Darren S Proppe
Although it is known that animals attend to the vocalizations of others (referred to as eavesdropping), what has been missing, or at least left experimentally unproven, until now is whether animals can learn new associations between a signal and a threat. Here Magrath and colleagues (Current Biology, 25(15), 2047-2050, 2015) have for the first time conducted a field experiment that demonstrates just this: superb fairy-wrens learned to associate a novel vocalization with a predator.
September 2016: Learning & Behavior
https://www.readbyqxmd.com/read/26650557/-ssri-and-bone-metabolism-in-hiv-patients-with-antiretroviral-therapy
#9
Martín J Mazzoglio y Nabar, Milagros María Muñiz, Alexis A Mejías Delamano, Santiago Muñoz, Nahuel Magrath Guimet
We report a series of 9 male HIV + patients, average age of 41.2 years, viral load negative (<50 copies RNA/ml), treated with antiretroviral (nucleoside and non-nucleoside inhibitors of reverse transcriptase) without systemic infections, the CNS diseases or marker or corticoidoterapia in progress. Were evaluated and supported by their infectologists interconsultation during the period October 2008-October 2013 by depressive syndrome. Psychotherapeutic and psychiatric treatment was initiated with SSRIs and clonazepam; Neuroimaging control and biochemical laboratory studies at baseline and 2 months of treatment were conducted...
May 2015: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/26578618/structural-barriers-to-diagnosis-and-treatment-of-cancer-in-low-and-middle-income-countries-the-urgent-need-for-scaling-up
#10
REVIEW
Eduardo Cazap, Ian Magrath, T Peter Kingham, Ahmed Elzawawy
Noncommunicable diseases are now recognized by the United Nations and WHO as a major public health crisis. Cancer is a main part of this problem, and health care systems are facing a great challenge to improve cancer care, control costs, and increase systems efficiency. The disparity in access to care and outcomes between high-income countries and low- and middle-income countries is staggering. The reasons for this disparity include cost, access to care, manpower and training deficits, and a lack of awareness in the lay and medical communities...
January 1, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/26469536/correlation-of-foveal-avascular-zone-size-with-foveal-morphology-in-normal-eyes-using-optical-coherence-tomography-angiography
#11
Wasim A Samara, Emil A T Say, Chloe T L Khoo, Timothy P Higgins, George Magrath, Sandor Ferenczy, Carol L Shields
PURPOSE: To analyze the foveal avascular zone (FAZ) in normal eyes using optical coherence tomography angiography. METHODS: Prospective noncomparative case series. The parafoveal region of 70 eyes from 67 healthy subjects was imaged using optical coherence tomography angiography to visualize the superficial and deep capillary plexuses and correlated with standard macular volume scans using spectral domain optical coherence tomography to determine foveal morphology...
November 2015: Retina
https://www.readbyqxmd.com/read/26416376/the-utility-of-radiological-upper-gastrointestinal-series-and-clinical-indicators-in-detecting-leaks-after-laparoscopic-sleeve-gastrectomy-a-case-controlled-study
#12
Monica Sethi, Melissa Magrath, Eduardo Somoza, Manish Parikh, John Saunders, Aku Ude-Welcome, Bradley Schwack, Marina Kurian, George Fielding, Christine Ren-Fielding
BACKGROUND: Leak after laparoscopic sleeve gastrectomy (LSG) often presents after hospital discharge, making timely diagnosis difficult. This study evaluates the utility of radiological upper gastrointestinal (UGI) series and clinical indicators in detecting leak after LSG. METHODS: A retrospective case-controlled study of 1762 patients who underwent LSG from 2006 to 2014 was performed. All patients with radiographically confirmed leaks were included. Controls consisted of patients who underwent LSG without leak, selected using a 10:1 case-match...
June 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26205561/previous-weight-loss-as-a-predictor-of-weight-loss-outcomes-after-laparoscopic-adjustable-gastric-banding
#13
Monica Sethi, Melissa Beitner, Melissa Magrath, Bradley Schwack, Marina Kurian, George Fielding, Christine Ren-Fielding
INTRODUCTION: Weight loss after laparoscopic adjustable gastric banding (LAGB) can be influenced by a variety of factors. The objective of this study is to investigate whether the maximum amount of previous weight loss with diet and exercise, prior to evaluation for bariatric surgery, is predictive of postoperative weight loss success among primary LAGB patients. METHODS: A retrospective cohort study was designed from a prospectively collected database at a single institution...
May 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26190077/wild-birds-learn-to-eavesdrop-on-heterospecific-alarm-calls
#14
Robert D Magrath, Tonya M Haff, Jessica R McLachlan, Branislav Igic
Many vertebrates gain critical information about danger by eavesdropping on other species' alarm calls [1], providing an excellent context in which to study information flow among species in animal communities [2-4]. A fundamental but unresolved question is how individuals recognize other species' alarm calls. Although individuals respond to heterospecific calls that are acoustically similar to their own, alarms vary greatly among species, and eavesdropping probably also requires learning [1]. Surprisingly, however, we lack studies demonstrating such learning...
August 3, 2015: Current Biology: CB
https://www.readbyqxmd.com/read/26176229/mini-and-maxi-peaks-of-combined-hamartoma-on-enhanced-depth-imaging-optical-coherence-tomography
#15
Chloe T L Khoo, George Magrath, Carol L Shields
A 17-year-old asymptomatic boy with a referral diagnosis of "macular gliosis" was found to have a combined hamartoma of the retina and retinal pigment epithelium. Enhanced depth imaging optical coherence tomography showed characteristic features of mini- and maxi-peaks from vitreoretinal traction.
2015: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/26170046/prediction-of-response-to-cardiac-resynchronization-therapy-using-left-ventricular-pacing-lead-position-and-cardiovascular-magnetic-resonance-derived-wall-motion-patterns-a-prospective-cohort-study
#16
Gregory R Hartlage, Jonathan D Suever, Stephanie Clement-Guinaudeau, Patrick T Strickland, Nima Ghasemzadeh, R Patrick Magrath, Ankit Parikh, Stamatios Lerakis, Michael H Hoskins, Angel R Leon, Michael S Lloyd, John N Oshinski
BACKGROUND: Despite marked benefits in many heart failure patients, a considerable proportion of patients treated with cardiac resynchronization therapy (CRT) fail to respond appropriately. Recently, a "U-shaped" (type II) wall motion pattern identified by cardiovascular magnetic resonance (CMR) has been associated with improved CRT response compared to a homogenous (type I) wall motion pattern. There is also evidence that a left ventricular (LV) lead localized to the latest contracting LV site predicts superior response, compared to an LV lead localized remotely from the latest contracting LV site...
2015: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/26092015/intraoperative-leak-testing-has-no-correlation-with-leak-after-laparoscopic-sleeve-gastrectomy
#17
Monica Sethi, Jonathan Zagzag, Karan Patel, Melissa Magrath, Eduardo Somoza, Manish S Parikh, John K Saunders, Aku Ude-Welcome, Bradley F Schwack, Marina S Kurian, George A Fielding, Christine J Ren-Fielding
BACKGROUND: Staple line leak is a serious complication of sleeve gastrectomy. Intraoperative methylene blue and air leak tests are routinely used to evaluate for leak; however, the utility of these tests is controversial. We hypothesize that the practice of routine intraoperative leak testing is unnecessary during sleeve gastrectomy. METHODS: A retrospective cohort study was designed using a prospectively collected database of seven bariatric surgeons from two institutions...
March 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26041353/crying-wolf-to-a-predator-deceptive-vocal-mimicry-by-a-bird-protecting-young
#18
Branislav Igic, Jessica McLachlan, Inkeri Lehtinen, Robert D Magrath
Animals often mimic dangerous or toxic species to deter predators; however, mimicry of such species may not always be possible and mimicry of benign species seems unlikely to confer anti-predator benefits. We reveal a system in which a bird mimics the alarm calls of harmless species to fool a predator 40 times its size and protect its offspring against attack. Our experiments revealed that brown thornbills (Acanthiza pusilla) mimic a chorus of other species' aerial alarm calls, a cue of an Accipiter hawk in flight, when predators attack their nest...
June 22, 2015: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/26036594/impacts-of-visitor-number-on-kangaroos-housed-in-free-range-exhibits
#19
Sally L Sherwen, Paul H Hemsworth, Kym L Butler, Kerry V Fanson, Michael J L Magrath
Free range exhibits are becoming increasingly popular in zoos as a means to enhance interaction between visitors and animals. However very little research exists on the impacts of visitors on animal behaviour and stress in free range exhibits. We investigated the effects of visitor number on the behaviour and stress physiology of Kangaroo Island (KI) Kangaroos, Macropus fuliginosus fuliginosus, and Red Kangaroos, Macropus rufus, housed in two free range exhibits in Australian zoos. Behavioural observations were conducted on individual kangaroos at each site using instantaneous scan sampling to record activity (e...
July 2015: Zoo Biology
https://www.readbyqxmd.com/read/25992541/multimodal-imaging-for-detection-of-clinically-inapparent-diffuse-iris-juvenile-xanthogranuloma
#20
Wasim A Samara, Chloe T L Khoo, George Magrath, Carol L Shields
A 6-month-old female infant was referred following three episodes of spontaneous hyphema. Iris juvenile xanthogranuloma was suspected but not clinically visible. Multimodal imaging with fluorescein angiography, anterior segment optical coherence tomography, and ultrasound biomicroscopy were used to detect the flat, transparent lesion and cytopathology confirmed juvenile xanthogranuloma.
2015: Journal of Pediatric Ophthalmology and Strabismus
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