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Infective endocarditis

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https://www.readbyqxmd.com/read/29452115/bioprosthetic-versus-mechanical-valve-replacement-for-infective-endocarditis-focus-on-recurrence-rates
#1
Nana Toyoda, Shinobu Itagaki, Henry Tannous, Natalia N Egorova, Joanna Chikwe
BACKGROUND: Consensus guidelines for prosthesis selection in infective endocarditis recommend bioprosthetic or mechanical valve replacement based on life expectancy and comorbidity. However, contemporary outcome data are limited to institution series. METHODS: The outcomes of 3,447 patients identified from mandatory discharge databases in California and New York states who had either primary isolated mitral (n=1603) or aortic (n=1,844) valve replacement for active endocarditis between 1998 and 2010, were compared according to whether they received bioprosthetic (n=1,673, 48...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29450741/utility-of-cardiac-computed-tomography-scanning-in-the-diagnosis-and-pre-operative-evaluation-of-patients-with-infective-endocarditis
#2
Jason R Sims, Nandan S Anavekar, Krishnaswamy Chandrasekaran, James M Steckelberg, Walter R Wilson, Bernard J Gersh, Larry M Baddour, Daniel C DeSimone
Transesophageal echocardiography (TEE) is the gold standard imaging study used in the diagnosis of infective endocarditis (IE). Computed tomography angiography (CTA) has undergone rapid advancement as a cardiac imaging technique and has previously shown promise in small non-randomized studies for evaluation of IE. We hypothesized that cardiac CTA would perform similarly to TEE in the detection of endocarditic lesions and that there would be no difference in clinical outcomes whether the coronary arteries were evaluated by CTA or invasive coronary angiography (ICA)...
February 15, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29448257/nonbacterial-thrombotic-endocarditis-presenting-with-leg-pain-and-a-left-atrial-mass-lesion
#3
Ahmed A Abouarab, Adham Elmously, Jeremy R Leonard, Mohammed J Arisha, Mario Gaudino, Naveent Narula, Arash Salemi
Systemic lupus erythematosus (SLE) is a major cause of nonbacterial thrombotic endocarditis (NBTE) associated with intracardiac sterile vegetations. It is rare for vegetations to present as an atrial tumor. This report describes a 48-year-old female with SLE and antiphospholipid syndrome complicated by recurrent thrombosis on anticoagulation. A large left atrial mass lesion was detected on echocardiography during a work-up for leg burning. Infective endocarditis could not be confirmed, and hence left atrial mass lesion was the most likely diagnosis...
February 15, 2018: Cardiology
https://www.readbyqxmd.com/read/29445480/hemolytic-anemia-due-to-native-valve-subacute-endocarditis-with-actinomyces-israelii-infection
#4
Sudhamshi Toom, Yiqing Xu
This case highlights the importance of considering infectious etiology in the management of hemolytic anemia. Hemolytic anemia associated with infectious endocarditis is rare. Actinomyces endocarditis is a rare occurrence and is very challenging to diagnose given the challenges to culture the organism.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29444729/gemella-bergeri-infective-endocarditis-a-case-report-and-brief-review-of-literature
#5
S Javed Zaidi, Tarek Husayni, Mary A Collins
Gemella is a genus of Gram-positive bacteria found in the digestive tract of humans. They rarely cause systemic illness but have been recently implicated in several serious infections. We report infective endocarditis caused by Gemella bergeri in a 23-year-old with a bicuspid aortic valve status post-intervention in infancy.
February 15, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29442340/aortic-valve-replacement-using-autologous-pericardium-single-centre-experience-with-the-ozaki-technique
#6
Oliver Reuthebuch, Luca Koechlin, Ulrich Schurr, Martin Grapow, Jens Fassl, Friedrich S Eckstein
OBJECTIVE: To assess the clinical implementation and report preliminary results of a novel technique called the Ozaki procedure for stentless aortic valve replacement through reconstruction of the valve leaflets from autologous pericardium. METHOD: Between September 2015 and May 2017 30 patients (20 males, mean ± standard deviation age 66.83 ± 10.55 years) suffering from aortic stenosis (AS, n = 7), aortic regurgitation (AR, n = 12), or a combination of both (AS/AR, n = 11) were assigned for an Ozaki procedure...
February 14, 2018: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29440841/acquired-ventricular-septal-defect-due-to-infective-endocarditis
#7
Randi E Durden, Joseph W Turek, Benjamin E Reinking, Manish Bansal
Acquired intracardiac left-to-right shunts are rare occurrences. Chest trauma and myocardial infection are well-known causes of acquired ventricular septal defect (VSD). There have been several case reports describing left ventricle to right atrium shunt after infective endocarditis (IE). We present here a patient found to have an acquired VSD secondary to IE of the aortic and tricuspid valves in the setting of a known bicuspid aortic valve. This is the first case reported of acquired VSD in a pediatric patient in the setting of IE along with literature review of acquired left-to-right shunts...
January 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29438479/novel-tn916-like-elements-confer-aminoglycoside-macrolide-co-resistance-in-clinical-isolates-of-streptococcus-gallolyticus-ssp-gallolyticus
#8
Stanimir Kambarev, Frédéric Pecorari, Stéphane Corvec
Background: Streptococcus gallolyticus ssp. gallolyticus (Sgg) is a commensal bacterium and an opportunistic pathogen. In humans it has been clinically associated with the incidence of colorectal cancer (CRC) and epidemiologically recognized as an emerging cause of infective endocarditis (IE). The standard therapy of Sgg includes the administration of a penicillin in combination with an aminoglycoside. Even though penicillin-resistant isolates have still not been reported, epidemiological studies have shown that this microbe is a reservoir of multiple acquired genes, conferring resistance to tetracyclines, aminoglycosides, macrolides and glycopeptides...
February 9, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29435864/current-knowledge-among-japanese-experienced-general-dentists-regarding-prevention-of-infective-endocarditis
#9
Ryota Nomura, Kazuma Kokomoto, Takahiro Ohara, Satoshi Nakatani, Takashi Ooshima, Kazuhiko Nakano
Infective endocarditis (IE), a life-threatening condition predominantly occurring in patients with underlying heart disease, is mainly caused by bacteremia induced by invasive dental treatment. However, the amount of related information shared between cardiologists and dentists appears to be inadequate. In the present study, a survey regarding prevention of IE, composed of 13 major questions, 2 of which also allowed free comments, was sent to approximately 3000 dentists belonging to a prefectural dental association in Japan...
February 12, 2018: Odontology
https://www.readbyqxmd.com/read/29430138/relative-presence-of-streptococcus-mutans-veillonella-atypica-and-granulicatella-adiacens-in-biofilm-of-complete-dentures
#10
Binoy Mathews Nedumgottil
Aims and Objective: Oral biofilms in denture wearers are populated with a large number of bacteria, a few of which have been associated with medical conditions such as sepsis and infective endocarditis (IE). The present study was designed to investigate the relative presence of pathogenic bacteria in biofilms of denture wearers specifically those that are associated with IE. Methods: Biofilm samples from 88 denture wearers were collected and processed to extract total genomic DNA...
January 2018: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/29429763/a-broad-range-pcr-technique-for-the-diagnosis-of-infective-endocarditis
#11
Ines Boujelben, Radhouane Gdoura, Adnane Hammami
Infective endocarditis (IE) remains a severe and potentially fatal disease demanding sophisticated diagnostic strategies for detection of the causative microorganisms. The aim of the present study was to develop a broad-range 16S ribosomal RNA gene polymerase chain reaction in the routine diagnostic of IE for the early diagnosis of fatal disease. A broad-range PCR technique was selected and evaluated in terms of its efficiency in the diagnosis of endocarditis using 19 heart valves from patients undergoing cardiovascular surgeries at the Habib Bourguiba Hospital of Sfax, Tunisia, on the grounds of suspected IE...
February 8, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29428976/spa-type-distribution-in-mrsa-and-mssa-bacteremias-and-association-of-spa-clonal-complexes-with-the-clinical-characteristics-of-bacteremia
#12
Elina Jokinen, Laura Lindholm, Reetta Huttunen, Heini Huhtala, Risto Vuento, Jaana Vuopio, Jaana Syrjänen
The genetic distribution of invasive methicillin-susceptible (MSSA) and resistant S. aureus (MRSA) strains has to be addressed in order to target infection control strategies. A large MRSA epidemic caused by a certain MRSA strain (spa type 067) broke out in 2001 in our health district. We wanted to investigate the current spa type distribution in MRSA and MSSA bacteremias and assess the potential association of spa clonal complexes (spaCC) with the clinical characteristics of S. aureus bacteremia. One hundred nine invasive MRSA isolates and 353 invasive MSSA isolates were spa typed and grouped into clonal complexes (spaCC)...
February 10, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29426281/primary-percutaneous-coronary-intervention-during-st-elevation-myocardial-infarction-in-prosthetic-valve-endocarditis-a-case-report
#13
Alfonso Campanile, Guido Tavazzi, Francesco Caprioglio, Fausto Rigo
BACKGROUND: Infective endocarditis (IE) is still a condition with high mortality and morbidity, especially in the elderly, and in patients with prosthetic valves. The concept of "time-to-therapy" plays a key role for the prompt management of IE and related complications, and the currently available multimodality imaging may play a key role in this setting. Myocardial ischemia due to extrinsic coronary compression from an aortic abscess is an extremely rare condition where the optimal therapeutic strategy has not been defined yet...
February 9, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29423161/infective-endocarditis-embolic-stroke-and-splenic-abscess-a-case-report
#14
Megan E Lindsey, Christopher T Holley, Archana Ramaswamy, Rosemary F Kelly
We present the case of a patient presenting with embolic stroke secondary to aortic valve endocarditis, additionally complicated by splenic abscess, successfully treated by emergent valve replacement followed by delayed, robotic splenectomy.
September 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29419663/emphysematous-endocarditis-caused-by-ampc-beta-lactamase-producing-escherichia-coli-a-case-report
#15
Chung-Jong Kim, Jeong-Eun Yi, Yookyung Kim, Hee Jung Choi
RATIONALE: Infective endocarditis (IE) is a life-threatening disease, mostly caused by gram-positive bacteria. Gram-negative bacteria were identified as a causative organism in relatively small number of cases. Although, antibiotic-resistant Escherichia coli is common cause of gram-negative endocarditis, AmpC beta-lactamase (BL)-harboring E coli is very rare cause of IE. Furthermore, emphysematous endocarditis is also a very rare manifestation of E coli infection. PATIENT CONCERNS: We report a case of 80-year-old female patient presenting with dizziness, fever, and altered mental status, who was finally diagnosed with emphysematous endocarditis caused by E coli harboring an AmpC BL gene...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29417312/lessons-learned-from-splenic-infarcts-with-fever-of-unknown-origin-fuo-culture-negative-endocarditis-cne-or-malignancy
#16
REVIEW
Burke A Cunha, Bertamaria Dieguez, Alena Varantsova
Culture negative endocarditis (CNE) is a common concern in patients with fever, heart murmur, cardiac vegetation, and negative blood cultures. The diagnosis of CNE is not based only on negative blood cultures and a cardiac vegetation. The clinical definition of CNE is based on negative blood cultures plus the findings of culture positive infective endocarditis (IE), e.g., fever, cardiac vegetation, splenomegaly, peripheral manifestations. Because embolic splenic infarcts may occur with culture positive IE, some may assume that splenic infarcts are a sign of CNE...
February 7, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29413230/the-diagnosis-of-microorganism-involved-in-infective-endocarditis-ie-by-polymerase-chain-reaction-pcr-and-real-time-pcr-a-systematic-review
#17
REVIEW
Reza Faraji, Mostafa Behjati-Ardakani, Seyed Mohammad Moshtaghioun, Seyed Mehdi Kalantar, Seyedeh Mahdieh Namayandeh, Mohammadhossien Soltani, Mahmood Emami, Hengameh Zandi, Ali Dehghani Firoozabadi, Mahmood Kazeminasab, Nastaran Ahmadi, Mohammadtaghi Sarebanhassanabadi
Broad-range bacterial rDNA polymerase chain reaction (PCR) followed by sequencing may be identified as the etiology of infective endocarditis (IE) from surgically removed valve tissue; therefore, we reviewed the value of molecular testing in identifying organisms' DNA in the studies conducted until 2016. We searched Google Scholar, Scopus, ScienceDirect, Cochrane, PubMed, and Medline electronic databases without any time limitations up to December 2016 for English studies reporting microorganisms involved in infective endocarditis microbiology using PCR and real-time PCR...
February 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/29409744/prognostic-implications-of-a-negative-echocardiography-in-patients-with-infective-endocarditis
#18
Lourdes Vicent, Hugo González Saldivar, Emilio Bouza, Patricia Muñoz, Gregorio Cuerpo, Aristides de Alarcón, Bárbara Vidal, Manuel Cobo, Miguel Ángel Goenaga, Fernando Carrasco-Chinchilla, Miguel Montejo, Juan Gálvez-Acebal, Carmen Hidalgo-Tenorio, David Vinuesa-García, Manuel Martínez-Sellés
BACKGROUND: Echocardiography plays an important role in infective endocarditis (IE) diagnosis according with the modified Duke criteria. We evaluated the implications of a positive echocardiography in the prognosis of a cohort of patients with IE. METHODS: Prospective multicentre study in 31 Spanish centres. From January 2008 to September 2016, 3467 patients were included (2765 definite IE, 702 possible IE). The main outcome was in-hospital mortality. Echocardiography diagnosis was based on modified Duke criteria for the diagnosis of IE...
February 3, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29408674/incidence-of-hacek-bacteraemia-in-denmark-a-6-year-population-based-study
#19
Lisbeth Lützen, Bente Olesen, Marianne Voldstedlund, Jens J Christensen, Claus Moser, Jenny D Knudsen, Kurt Fuursted, Gitte N Hartmeyer, Ming Chen, Turid S Søndergaard, Flemming S Rosenvinge, Esad Dzajic, Henrik C Schønheyder, Niels Nørskov-Lauritsen
OBJECTIVES: Bacteria with common microbiological and clinical characteristics are often recognized as a particular group. The acronym HACEK stands for five fastidious genera associated with infective endocarditis. Data on the epidemiology of HACEK are sparse and therefore we report a six-year nationwide study of HACEK bacteraemia in Denmark. METHODS: Cases of HACEK bacteraemia 2010 through 2015 were retrieved from the national Danish Microbiology Database covering an average surveillance population of 5...
January 31, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29408350/a-pragmatic-approach-for-mortality-prediction-after-surgery-in-infective-endocarditis-optimizing-and-refining-euroscore
#20
Nuria Fernández-Hidalgo, Ignacio Ferreria-González, Josep R Marsal, Aida Ribera, María L Aznar, Arístides de Alarcón, Emilio García-Cabrera, Juan Gálvez-Acebal, Gemma Sánchez-Espín, José M Reguera-Iglesias, Javier De La Torre-Lima, José M Lomas, Carmen Hidalgo-Tenorio, Nuria Vallejo, Berta Miranda, Alba Santos-Ortega, Miguel A Castro, Pilar Tornos, David García-Dorado, Benito Almirante
OBJECTIVE: To simplify and optimize EuroSCORE I and II ability to predict early mortality after surgery of infective endocarditis (IE). METHODS: Multicenter retrospective study (n=775). Simplified scores, eliminating irrelevant variables, and new specific scores, adding specific IE variables, were created. The performance of the original, recalibrated and specific EuroSCOREs was assessed by Brier score, C-statistic, and calibration plot in bootstrap samples. The Net Reclassification Index (NRI) was quantified...
February 2, 2018: Clinical Microbiology and Infection
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