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Infective endocarditis

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https://www.readbyqxmd.com/read/29240776/microbiological-profile-and-risk-factors-for-in-hospital-mortality-of-infective-endocarditis-in-tertiary-care-hospitals-of-south-vietnam
#1
Hoang M Tran, Vien T Truong, Tam M N Ngo, Quoc P V Bui, Hoang C Nguyen, Trung T Q Le, Wojciech Mazur, Eugene Chung, John M Cafardi, Khanh P N Pham, Hoang H N Duong, Thach Nguyen, Vu T Nguyen, Vinh N Pham
OBJECTIVES: We aimed to evaluate the microbiological characteristics and risk factors for mortality of infective endocarditis in two tertiary hospitals in Ho Chi Minh City, south Vietnam. MATERIALS AND METHODS: A retrospective study of 189 patients (120 men, 69 women; mean age 38 ± 18 years) with the diagnosis of probable or definite infective endocarditis (IE) according to the modified Duke Criteria admitted to The Heart Institute or Tam Duc Hospital between January 2005 and December 2014...
2017: PloS One
https://www.readbyqxmd.com/read/29238620/angiovac-system-used-for-vegetation-debulking-in-a-patient-with-tricuspid-valve-endocarditis-a-case-report-and-review-of-the-literature
#2
Hossam Abubakar, Ahmed Rashed, Ahmed Subahi, Ahmed S Yassin, Mohamed Shokr, Mahir Elder
AngioVac is a vacuum-based device approved in 2014 for percutaneous removal of undesirable materials from the intravascular system. Although numerous reports exist with regard to the use of the AngioVac device in aspiration of iliocaval, pulmonary, upper extremity, and right-sided heart chamber thrombi, very few data are present demonstrating its use in treatment of right-sided endocarditis. In this case report, we describe the novel device used in debulking a large right-sided tricuspid valve vegetation reducing the occurrence of septic embolisation and enhancing the efficacy of antibiotics in clearance of bloodstream infection...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29238457/molecular-detection-of-bordetella-holmesii-in-two-infants-with-pertussis-like-syndrome-the-first-report-from-iran
#3
Masoumeh Nakhost Lotfi, Vajiheh Sadat Nikbin, Omid Nasiri, Farzad Badmasti, Fereshteh Shahcheraghi
Background and Objectives: Bordetella holmesii is associated with a pertussis-like respiratory syndrome in healthy individuals and also a rare cause of septicaemia, endocarditis, pneumonia, and septic arthritis, mostly in immunocompromised patients. Culture technique and real-time PCR are 2 methods used to detect Bordetella spp. Materials and Methods: In this study, 435 nasopharyngeal specimens of patients with suspected whooping cough were checked for the presence of B...
August 2017: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/29238455/in-vitro-activity-of-recombinant-lysostaphin-in-combination-with-linezolid-vancomycin-and-oxacillin-against-methicillin-resistant-staphylococcus-aureus
#4
Nagalakshmi Narasimhaswamy, Indira Bairy, Gautham Shenoy, Laxminarayana Bairy
Background and Objectives: The antimicrobial combination with synergistic mechanism is recommended to provide broad-spectrum coverage, and prevent the emergence of resistant mutants. In the present study, the synergistic activity of lysostaphin with linezolid, oxacillin and vancomycin, against methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates was determined. Materials and Methods: Seventy-three MRSA isolates collected from clinical specimens were tested, for in vitro synergistic activity of lysostaphin with linezolid, vancomycin and oxacillin, by checkerboard assay...
August 2017: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/29238103/clinical-features-of-patients-with-infective-endocarditis-presenting-to-the-emergency-department-a-retrospective-case-series
#5
Naruhiro Jingushi, Mitsunaga Iwata, Teruhiko Terasawa
Infective endocarditis (IE) is an uncommon clinical problem with diverse, nonspecific presentations. Therefore, information on the clinical features of IE patients presenting to emergency departments (EDs) is scarce. To descriptively analyze the pertinent data, we performed a retrospective chart review. We reviewed 15 consecutive IE patients admitted directly from ED in a university hospital in Japan between 2013 and 2015. We compared their clinical features with those of 14 IE patients admitted during the same period without ED presentations...
November 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29234970/aortic-valve-reconstruction-using-autologous-pericardium-ozaki-procedure-for-active-infective-endocarditis-a-case-report
#6
Kimiaki Okada, Yoshito Inoue, Hirofumi Haida, Satoru Suzuki
Approximately one-third of patients with infective endocarditis require surgical treatment, but the ideal procedure that prevents infection ensures long durability and maintains quality of life remains unclear. A 21-year-old man who was diagnosed with aortic active infective endocarditis was referred to our hospital for surgical treatment. Echocardiography showed bicuspid aortic valve, severe aortic regurgitation, a large vegetation, and a paravalvular abscess. We planned to perform elective surgical treatment after antibiotic therapy; however, progression to heart failure required urgent operation...
December 12, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29233766/use-of-the-perceval-sutureless-valve-in-active-prosthetic-aortic-valve-endocarditis
#7
Elena Roselló-Díez, Gregorio Cuerpo, Francisco Estévez, C Christian Muñoz-Guijosa, Manel Tauron, José J Cuenca, Ángel Pinto, Josep María Padró
BACKGROUND: Surgical treatment of active prosthetic aortic valve endocarditis presents a challenge for cardiac surgeons because of tissue friability and destruction caused by infection. Sutureless prostheses, such as the Perceval S® (LivaNova, Saluggia, Italy), have emerged as an option among the different surgical approaches for these complicated cases. METHODS: This study presents data from nine patients who underwent aortic valve re-replacement with the Perceval S® due to active prosthetic aortic valve endocarditis, between January 2014 and August 2016...
December 9, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29233359/supra-annular-mitral-valve-replacement-in-an-infant-with-infective-endocarditis
#8
Sanae Yamauchi, Shigemitsu Iwai, Yuji Tominaga, Yosuke Kugo, Moyu Hasegawa, Futoshi Kayatani, Kunihiko Takahashi, Hisaaki Aoki, Hiroaki Kawata
We report the case of a female neonate born at 40 weeks' gestation with no known risk factors. On postnatal day 27, she was transferred to the pediatric intensive care unit and intubated for cardiorespiratory failure; she was diagnosed with group B streptococcus infective endocarditis. Mitral valve vegetations did not improve with antibiotic therapy. Mitral valve surgery was performed on postnatal day 36. A mechanical mitral valve with short-segment polytetrafluoroethylene skirt was inserted into the supra-annular position; gentian violet was applied to the sewing ring and skirt...
January 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29233094/short-and-long-term-outcomes-in-infective-endocarditis-patients-a-systematic-review-and-meta-analysis
#9
Tadesse Melaku Abegaz, Akshaya Srikanth Bahagavathula, Eyob Alemayehu Gebreyohannes, Alemayehu B Mekonnen, Tamrat Befekadu Abebe
BACKGROUND: Despite advances in medical knowledge, technology and antimicrobial therapy, infective endocarditis (IE) is still associated with devastating outcomes. No reviews have yet assessed the outcomes of IE patients undergoing short- and long-term outcome evaluation, such as all-cause mortality and IE-related complications. We conducted a systematic review and meta-analysis to examine the short- and long-term mortality, as well as IE-related complications in patients with definite IE...
December 12, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29232248/endocarditis-in-the-setting-of-idu-multidisciplinary-management
#10
Bobby Yanagawa, Anees Bahji, Wiplove Lamba, Darrell H Tan, Asim Cheema, Ishba Syed, Subodh Verma
PURPOSE OF REVIEW: The purpose of this article is to provide a brief overview of the medical and surgical management of infective endocarditis secondary to IDU, with a focus on the underlying substance use disorder. RECENT FINDINGS: Patients with infective endocarditis secondary to IDU are often young with unique comorbidities including mental illness, chronic hepatitis C, HIV infection, which are often compounded by limited social and familial supports. The focus of management has been treatment of endocarditis using IV antibiotics alongside surgery...
December 11, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29231915/lactobacillus-gasseri-endocarditis-on-the-aortic-valve-bioprosthesis-a-case-report
#11
Waldemar Elikowski, Małgorzata Małek-Elikowska, Monika Lisiecka, Anna Bodora, Katarzyna Wiśniewska, Zofia Oko-Sarnowska
Lactobacillus is a genus of Gram-positive, facultative anaerobic/ microaerophilic, rod-shaped bacteria. Lactobacilli constitute a significant component of the human microbiota in the oral cavity, gastrointestinal tract and female urogenital tract. They are also widely used as probiotics. Rarely, especially in patients with impaired immunity or with structural heart disease, do Lactobacilli become the pathogen responsible for serious infections, e.g. infective endocarditis (IE). CASE REPORT: The authors describe a case of an 80-year-old female with a past history of aortic valve replacement, mitral annuloplasty and pacemaker implantation admitted to hospital due to weakening, subfebrile state and chills...
November 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29229737/the-superantigen-toxic-shock-syndrome-toxin-1-alters-human-aortic-endothelial-cell-function
#12
Katarina Kulhankova, Kyle J Kinney, Jessica M Stach, Françoise A Gourronc, Isabella M Grumbach, Aloysius J Klingelhutz, Wilmara Salgado-Pabón
Staphylococcus aureus infective endocarditis (IE) is a fast-progressing and tissue destructive infection of the cardiac endothelium. The superantigens (SAgs) toxic shock syndrome toxin-1 (TSST-1), staphylococcal enterotoxin C (SEC), and the enterotoxin gene cluster (egc) play a novel and essential role in the etiology of S. aureus IE. Recent studies indicate that SAgs act at the infection site to cause tissue pathology and promote vegetation growth. The underlying mechanism of SAg involvement has not been clearly defined...
December 11, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/29229734/macrophage-polarization-alters-post-phagocytosis-survivability-of-the-commensal-streptococcus-gordonii
#13
Andrew J Croft, Sarah Metcalfe, Kiyonobu Honma, Jason G Kay
Oral streptococci are generally considered commensal organisms; however, they are becoming recognized as important associate pathogens during the development of periodontal disease as well as being associated with several systemic diseases, including as a causative agent of infective endocarditis. An important virulence determinant of these bacteria is an ability to evade destruction by phagocytic cells, yet how this subversion occurs is mostly unknown. Using Streptococcus gordonii as a model commensal oral streptococcus that is also associated with disease, we find resistance to reactive oxygen species (ROS) with an active ability to damage phagosomes allows the bacterium to avoid destruction within macrophages...
December 11, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/29229070/infective-endocarditis-an-update-for-dental-surgeons
#14
REVIEW
Andrew Narendran Robinson, Paul Anantharajah Tambyah
Infective endocarditis (IE) is associated with significant morbidity and mortality. The prevention of infective endocarditis, for many years, has involved the identification of at risk patients undergoing medical or dental procedures and the use of pre-procedural antibiotic prophylaxis. However, evidence regarding the effectiveness of such measures is lacking while evidence is mounting for the adverse effects of inappropriate antibiotic use. International guidelines for antibiotic prophylaxis were amended, radically in some cases to reflect this...
December 2017: Singapore Dental Journal
https://www.readbyqxmd.com/read/29228242/mortality-risk-prediction-in-infective-endocarditis-surgery-reliability-analysis-of-specific-scores
#15
Laura Varela, Jose López-Menéndez, Ana Redondo, Edmundo Ricardo Fajardo, Javier Miguelena, Tomasa Centella, Miren Martín, Rafael Muñoz, Enrique Navas, Jose Luis Moya, Jorge Rodríguez-Roda
OBJECTIVES: We assessed the prognostic utility of risk scores in surgery for infective endocarditis (IE) to evaluate their reliability in mortality risk prediction. METHODS: An observational retrospective study was developed to include all patients who underwent surgery for active IE from 2002 to 2016. Classical and endocarditis-specific risk scores were calculated. RESULTS: A total of 180 patients were included in the study. The 30-day mortality rate was 26...
December 8, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29225626/hemothorax-due-to-ruptured-mycotic-aneurysm-of-intercostal-arteries-associated-with-infective-endocarditis
#16
Eddie Y Liu, Jennifer Crawford, Haissam Haddad
We present a case of hemothorax due to ruptured mycotic aneurysm in three intercostal arteries in a 40-year-old male with methicillin-resistant Staphylococcus aureus infective endocarditis (IE) due to intravenous drug use. Microcoil embolization and thoracotomy successfully achieved hemostasis. Mycotic aneurysm is a rare complication of IE and is usually found in the intracranial vessels. Ruptured mycotic aneurysm in the intercostal arteries can be associated with IE and can present as acute hemothorax.
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/29225261/a-case-of-isolated-left-atrial-infective-mural-endocarditis
#17
Saki Hosokawa, Hideki Okayama, Go Hiasa, Go Kawamura, Tatsuya Shigematsu, Tatsunori Takahashi, Yoshitaka Kawada, Tadakatsu Yamada, Hiroshi Matsuoka, Yukio Kazatani
A 52-year-old man presented with a fever and malaise. Transthoracic echocardiogram was performed because of a holosystolic murmur, which showed mitral valve prolapse and a regurgitation jet toward the posterior wall of the left atrium. There was no apparent vegetation at any valves. Blood cultures were positive for Streptococcus mitis/oralis. Transesophageal echocardiogram revealed vegetation only at the posterior wall of the left atrium exposed to the mitral regurgitant jet. We diagnosed this condition as infective mural endocarditis...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29225254/observational-study-of-infective-endocarditis-at-a-community-based-hospital-dominance-of-elderly-patients-with-comorbidity
#18
Tomoo Nagai, Yoshiyuki Takase, Akira Hamabe, Hirotsugu Tabata
Objective The purpose of this study was to present the recent clinical profiles and the real-world management of infective endocarditis (IE). Methods All medical records of patients with IE were reviewed retrospectively for their clinical data, including clinical presentation, laboratory results, blood cultures, echocardiographic findings, treatments and complications. Using the clinical data collected, we calculated the EuroSCORE II, the European risk score for adult cardiac surgery, the Charlson Comorbidity Index as a surrogate of comordibity, and the Katz Index as a surrogate of frailty...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29224640/return-to-the-workforce-following-infective-endocarditis-a-nationwide-cohort-study
#19
Jawad H Butt, Kristian Kragholm, Michael Dalager-Pedersen, Rasmus Rørth, Søren L Kristensen, Mavish S Chaudry, Nana Valeur, Lauge Østergaard, Christian Torp-Pedersen, Gunnar H Gislason, Lars Køber, Emil L Fosbøl
BACKGROUND: The ability to return to work after infective endocarditis (IE) holds important socioeconomic consequences for both patients and society, yet data on this issue are sparse. We examined return to the workforce and associated factors in IE patients of working age. METHODS: Using Danish nationwide registries, we identified 1,065 patients aged 18-60 years with a first-time diagnosis of IE (1996-2013) who were part of the workforce prior to admission and alive at discharge...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29211885/outcome-of-surgical-intervention-for-aortic-root-abscess-a-meta-analysis
#20
Guan-Jhou Chen, Wei-Cheng Lo, Hsien-Wei Tseng, Sung-Ching Pan, Yih-Sharng Chen, Shan-Chwen Chang
OBJECTIVES: Aortic root abscess (ARA) is a catastrophic complication of aortic root endocarditis, involving both native and prosthetic valves, which often warrants surgical intervention. Currently, aortic valve replacement (AVR) and aortic root replacement (ARR) are the most widely employed techniques. However, evidence that directly compares these methods is scarce. In this meta-analysis, we aimed to describe the surgical outcome of ARA when using different surgical methods. METHODS: In this meta-analysis, we performed literature searches in the EMBASE and PubMed databases and reviewed articles describing postoperative results of ARA that were published before 30 June 2016...
December 2, 2017: European Journal of Cardio-thoracic Surgery
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